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Items: 1 to 50 of 54

1.

Matrix-Assisted Laser Desorption Ionization Mapping of Lysophosphatidic Acid Changes after Traumatic Brain Injury and the Relationship to Cellular Pathology.

McDonald WS, Jones EE, Wojciak JM, Drake RR, Sabbadini RA, Harris NG.

Am J Pathol. 2018 Aug;188(8):1779-1793. doi: 10.1016/j.ajpath.2018.05.005. Epub 2018 Jul 16.

2.

Nervous system delivery of antilysophosphatidic acid antibody by nasal application attenuates mechanical allodynia after traumatic brain injury in rats.

Eisenried A, Meidahl ACN, Klukinov M, Tzabazis AZ, Sabbadini RA, Clark JD, Yeomans DC.

Pain. 2017 Nov;158(11):2181-2188. doi: 10.1097/j.pain.0000000000001019.

PMID:
29028747
3.

Acid ceramidase confers radioresistance to glioblastoma cells.

Doan NB, Nguyen HS, Al-Gizawiy MM, Mueller WM, Sabbadini RA, Rand SD, Connelly JM, Chitambar CR, Schmainda KM, Mirza SP.

Oncol Rep. 2017 Oct;38(4):1932-1940. doi: 10.3892/or.2017.5855. Epub 2017 Jul 28.

4.

Sphingosine 1-phosphate signaling through its receptor S1P5 promotes chromosome segregation and mitotic progression.

Andrieu G, Ledoux A, Branka S, Bocquet M, Gilhodes J, Walzer T, Kasahara K, Inagaki M, Sabbadini RA, Cuvillier O, Hatzoglou A.

Sci Signal. 2017 Mar 28;10(472). pii: eaah4007. doi: 10.1126/scisignal.aah4007.

PMID:
28351953
5.

Essential role for SphK1/S1P signaling to regulate hypoxia-inducible factor 2α expression and activity in cancer.

Bouquerel P, Gstalder C, Müller D, Laurent J, Brizuela L, Sabbadini RA, Malavaud B, Pyronnet S, Martineau Y, Ader I, Cuvillier O.

Oncogenesis. 2016 Mar 14;5:e209. doi: 10.1038/oncsis.2016.13.

6.

Neutralizing S1P inhibits intratumoral hypoxia, induces vascular remodelling and sensitizes to chemotherapy in prostate cancer.

Ader I, Gstalder C, Bouquerel P, Golzio M, Andrieu G, Zalvidea S, Richard S, Sabbadini RA, Malavaud B, Cuvillier O.

Oncotarget. 2015 May 30;6(15):13803-21.

7.

Anti-S1P Antibody as a Novel Therapeutic Strategy for VEGFR TKI-Resistant Renal Cancer.

Zhang L, Wang X, Bullock AJ, Callea M, Shah H, Song J, Moreno K, Visentin B, Deutschman D, Alsop DC, Atkins MB, Mier JW, Signoretti S, Bhasin M, Sabbadini RA, Bhatt RS.

Clin Cancer Res. 2015 Apr 15;21(8):1925-1934. doi: 10.1158/1078-0432.CCR-14-2031. Epub 2015 Jan 14.

8.

Osteoblast-derived sphingosine 1-phosphate to induce proliferation and confer resistance to therapeutics to bone metastasis-derived prostate cancer cells.

Brizuela L, Martin C, Jeannot P, Ader I, Gstalder C, Andrieu G, Bocquet M, Laffosse JM, Gomez-Brouchet A, Malavaud B, Sabbadini RA, Cuvillier O.

Mol Oncol. 2014 Oct;8(7):1181-95. doi: 10.1016/j.molonc.2014.04.001. Epub 2014 Apr 13.

9.

Anti-lysophosphatidic acid antibodies improve traumatic brain injury outcomes.

Crack PJ, Zhang M, Morganti-Kossmann MC, Morris AJ, Wojciak JM, Fleming JK, Karve I, Wright D, Sashindranath M, Goldshmit Y, Conquest A, Daglas M, Johnston LA, Medcalf RL, Sabbadini RA, Pébay A.

J Neuroinflammation. 2014 Feb 27;11:37. doi: 10.1186/1742-2094-11-37.

10.

Blockage of lysophosphatidic acid signaling improves spinal cord injury outcomes.

Goldshmit Y, Matteo R, Sztal T, Ellett F, Frisca F, Moreno K, Crombie D, Lieschke GJ, Currie PD, Sabbadini RA, Pébay A.

Am J Pathol. 2012 Sep;181(3):978-92. doi: 10.1016/j.ajpath.2012.06.007. Epub 2012 Jul 20.

11.

Biological effects of lysophosphatidic acid in the nervous system.

Frisca F, Sabbadini RA, Goldshmit Y, Pébay A.

Int Rev Cell Mol Biol. 2012;296:273-322. doi: 10.1016/B978-0-12-394307-1.00005-9. Review.

PMID:
22559941
12.

Intracellular S1P generation is essential for S1P-induced motility of human lung endothelial cells: role of sphingosine kinase 1 and S1P lyase.

Berdyshev EV, Gorshkova I, Usatyuk P, Kalari S, Zhao Y, Pyne NJ, Pyne S, Sabbadini RA, Garcia JG, Natarajan V.

PLoS One. 2011 Jan 31;6(1):e16571. doi: 10.1371/journal.pone.0016571.

13.

Sphingosine-1-phosphate antibodies as potential agents in the treatment of cancer and age-related macular degeneration.

Sabbadini RA.

Br J Pharmacol. 2011 Mar;162(6):1225-38. doi: 10.1111/j.1476-5381.2010.01118.x. Review.

14.

Sphingosine-1-phosphate and sphingosine kinase are critical for transforming growth factor-beta-stimulated collagen production by cardiac fibroblasts.

Gellings Lowe N, Swaney JS, Moreno KM, Sabbadini RA.

Cardiovasc Res. 2009 May 1;82(2):303-12. doi: 10.1093/cvr/cvp056. Epub 2009 Feb 19.

15.

Sphingosine-1-phosphate (S1P) is a novel fibrotic mediator in the eye.

Swaney JS, Moreno KM, Gentile AM, Sabbadini RA, Stoller GL.

Exp Eye Res. 2008 Oct;87(4):367-75. doi: 10.1016/j.exer.2008.07.005. Epub 2008 Jul 18.

PMID:
18687328
16.

Trophic action of sphingosine 1-phosphate in denervated rat soleus muscle.

Zanin M, Germinario E, Dalla Libera L, Sandonà D, Sabbadini RA, Betto R, Danieli-Betto D.

Am J Physiol Cell Physiol. 2008 Jan;294(1):C36-46. Epub 2007 Oct 17.

17.

Immunization with non-replicating E. coli minicells delivering both protein antigen and DNA protects mice from lethal challenge with lymphocytic choriomeningitis virus.

Giacalone MJ, Zapata JC, Berkley NL, Sabbadini RA, Chu YL, Salvato MS, McGuire KL.

Vaccine. 2007 Mar 8;25(12):2279-87. Epub 2006 Dec 26.

18.

Targeting sphingosine-1-phosphate for cancer therapy.

Sabbadini RA.

Br J Cancer. 2006 Nov 6;95(9):1131-5. Epub 2006 Oct 3. Review.

19.

The use of bacterial minicells to transfer plasmid DNA to eukaryotic cells.

Giacalone MJ, Gentile AM, Lovitt BT, Xu T, Surber MW, Sabbadini RA.

Cell Microbiol. 2006 Oct;8(10):1624-33.

PMID:
16984417
20.

Immune responses elicited by bacterial minicells capable of simultaneous DNA and protein antigen delivery.

Giacalone MJ, Sabbadini RA, Chambers AL, Pillai S, Berkley NL, Surber MW, McGuire KL.

Vaccine. 2006 Aug 14;24(33-34):6009-17. Epub 2006 May 9. Erratum in: Vaccine. 2007 Apr 30;25(17):3515. Berkley, Neil L [added]; Surber, Mark W [added].

PMID:
16806602
21.

Validation of an anti-sphingosine-1-phosphate antibody as a potential therapeutic in reducing growth, invasion, and angiogenesis in multiple tumor lineages.

Visentin B, Vekich JA, Sibbald BJ, Cavalli AL, Moreno KM, Matteo RG, Garland WA, Lu Y, Yu S, Hall HS, Kundra V, Mills GB, Sabbadini RA.

Cancer Cell. 2006 Mar;9(3):225-38.

22.

Sphingosine 1-phosphate protects mouse extensor digitorum longus skeletal muscle during fatigue.

Danieli-Betto D, Germinario E, Esposito A, Megighian A, Midrio M, Ravara B, Damiani E, Libera LD, Sabbadini RA, Betto R.

Am J Physiol Cell Physiol. 2005 Jun;288(6):C1367-73. Epub 2005 Jan 19.

23.

Predicting obstructive coronary artery disease with serum sphingosine-1-phosphate.

Deutschman DH, Carstens JS, Klepper RL, Smith WS, Page MT, Young TR, Gleason LA, Nakajima N, Sabbadini RA.

Am Heart J. 2003 Jul;146(1):62-8.

PMID:
12851609
24.

Factor associated with neutral sphingomyelinase activation and its role in cardiac cell death.

O'Brien NW, Gellings NM, Guo M, Barlow SB, Glembotski CC, Sabbadini RA.

Circ Res. 2003 Apr 4;92(6):589-91. Epub 2003 Mar 13.

PMID:
12637370
25.

Expression and functional characterization of SCaMPER: a sphingolipid-modulated calcium channel of cardiomyocytes.

Cavalli AL, O'Brien NW, Barlow SB, Betto R, Glembotski CC, Palade PT, Sabbadini RA.

Am J Physiol Cell Physiol. 2003 Mar;284(3):C780-90. Epub 2002 Nov 6.

26.

Expression and characterization of Edg-1 receptors in rat cardiomyocytes: calcium deregulation in response to sphingosine 1-phosphate.

Nakajima N, Cavalli AL, Biral D, Glembotski CC, McDonough PM, Ho PD, Betto R, Sandoná D, Palade PT, Dettbarn CA, Klepper RE, Sabbadini RA.

Eur J Biochem. 2000 Sep;267(18):5679-86.

27.

The role of sphingolipids in the control of skeletal muscle function: a review.

Sabbadini RA, Danieli-Betto D, Betto R.

Ital J Neurol Sci. 1999 Dec;20(6):423-30. Review.

PMID:
10937863
28.

Myocardial cells in culture to study effects of cytokines.

Krown KA, Sabbadini RA.

Methods Mol Med. 2000;36:181-8. doi: 10.1385/1-59259-216-3:181.

PMID:
21340974
29.

LPS-induced TNF-alpha release from and apoptosis in rat cardiomyocytes: obligatory role for CD14 in mediating the LPS response.

Comstock KL, Krown KA, Page MT, Martin D, Ho P, Pedraza M, Castro EN, Nakajima N, Glembotski CC, Quintana PJ, Sabbadini RA.

J Mol Cell Cardiol. 1998 Dec;30(12):2761-75.

PMID:
9990546
30.

MKK6 activates myocardial cell NF-kappaB and inhibits apoptosis in a p38 mitogen-activated protein kinase-dependent manner.

Zechner D, Craig R, Hanford DS, McDonough PM, Sabbadini RA, Glembotski CC.

J Biol Chem. 1998 Apr 3;273(14):8232-9.

31.

Sphingosylphosphocholine modulates the ryanodine receptor/calcium-release channel of cardiac sarcoplasmic reticulum membranes.

Betto R, Teresi A, Turcato F, Salviati G, Sabbadini RA, Krown K, Glembotski CC, Kindman LA, Dettbarn C, Pereon Y, Yasui K, Palade PT.

Biochem J. 1997 Feb 15;322 ( Pt 1):327-33.

32.

Tumor necrosis factor alpha-induced apoptosis in cardiac myocytes. Involvement of the sphingolipid signaling cascade in cardiac cell death.

Krown KA, Page MT, Nguyen C, Zechner D, Gutierrez V, Comstock KL, Glembotski CC, Quintana PJ, Sabbadini RA.

J Clin Invest. 1996 Dec 15;98(12):2854-65.

33.

TNF alpha receptor expression in rat cardiac myocytes: TNF alpha inhibition of L-type Ca2+ current and Ca2+ transients.

Krown KA, Yasui K, Brooker MJ, Dubin AE, Nguyen C, Harris GL, McDonough PM, Glembotski CC, Palade PT, Sabbadini RA.

FEBS Lett. 1995 Nov 27;376(1-2):24-30.

34.

Control of cardiac Ca2+ levels. Inhibitory actions of sphingosine on Ca2+ transients and L-type Ca2+ channel conductance.

McDonough PM, Yasui K, Betto R, Salviati G, Glembotski CC, Palade PT, Sabbadini RA.

Circ Res. 1994 Dec;75(6):981-9.

PMID:
7955152
35.

Sphingosine effects on the contractile behavior of skinned cardiac myocytes.

Webster RJ, Sabbadini RA, Dettbarn CA, Paolini PJ.

J Mol Cell Cardiol. 1994 Oct;26(10):1273-90.

PMID:
7869389
36.

Modulation of cardiac sarcoplasmic reticulum ryanodine receptor by sphingosine.

Dettbarn CA, Betto R, Salviati G, Palade P, Jenkins GM, Sabbadini RA.

J Mol Cell Cardiol. 1994 Feb;26(2):229-42.

PMID:
8006984
37.

Dystrophin is phosphorylated by endogenous protein kinases.

Luise M, Presotto C, Senter L, Betto R, Ceoldo S, Furlan S, Salvatori S, Sabbadini RA, Salviati G.

Biochem J. 1993 Jul 1;293 ( Pt 1):243-7.

38.

The skeletal muscle transverse tubular Mg-ATPase: identity with Mg-ATPases of smooth muscle and brain.

Cunningham HB, Yazaki PJ, Domingo RC, Oades KV, Bohlen H, Sabbadini RA, Dahms AS.

Arch Biochem Biophys. 1993 May 15;303(1):32-43.

PMID:
8489264
39.

The effects of sphingosine on sarcoplasmic reticulum membrane calcium release.

Sabbadini RA, Betto R, Teresi A, Fachechi-Cassano G, Salviati G.

J Biol Chem. 1992 Aug 5;267(22):15475-84.

40.

Sphingosine inhibits calcium release from sarcoplasmic reticulum membranes.

Betto R, Teresi A, Fachechi-Cassano G, Salviati G, Sabbadini RA.

Adv Exp Med Biol. 1992;311:403-4. No abstract available.

PMID:
1529777
41.

Characterization of a muscle membrane ATPase glycoprotein.

Yazaki PJ, Cunningham HB, Kang JJ, Jachec C, Hunt SA, Domingo RC, Sabbadini RA, Dahms AS.

Adv Exp Med Biol. 1992;311:425-6. No abstract available.

PMID:
1388317
42.

Direct effects of phorbol esters and diacylglycerols on the T-tubule Mg(2+)-ATPase.

Kang JJ, Cunningham HB, Jachec C, Priest A, Dahms AS, Sabbadini RA.

Arch Biochem Biophys. 1991 Oct;290(1):214-23.

PMID:
1832847
43.
44.

Biochemical properties of isolated transverse tubular membranes.

Sabbadini RA, Dahms AS.

J Bioenerg Biomembr. 1989 Apr;21(2):163-213. Review.

PMID:
2473982
45.

Common structural domains in the sarcoplasmic reticulum Ca-ATPase and the transverse tubule Mg-ATPase.

Damiani E, Margreth A, Furlan A, Dahms AS, Arnn J, Sabbadini RA.

J Cell Biol. 1987 Mar;104(3):461-72.

46.

Studies on the transverse tubule membrane Mg-ATPase. Lectin-induced alterations of kinetic behavior.

Moulton MP, Sabbadini RA, Norton KC, Dahms AS.

J Biol Chem. 1986 Sep 15;261(26):12244-51.

47.

Characterization of transverse tubule membrane proteins: tentative identification of the Mg-ATPase.

Okamoto VR, Moulton MP, Runte EM, Kent CD, Lebherz HG, Dahms AS, Sabbadini RA.

Arch Biochem Biophys. 1985 Feb 15;237(1):43-54.

PMID:
3155929
48.

The distribution of ATPase activities in purified transverse tubular membranes.

Sabbadini RA, Okamoto VR.

Arch Biochem Biophys. 1983 May;223(1):107-19. No abstract available.

PMID:
6305271
50.

Lipid composition of transverse tubular membranes from normal and dystrophic skeletal muscle.

Sumnicht GE, Sabbadini RA.

Arch Biochem Biophys. 1982 May;215(2):628-37. No abstract available.

PMID:
7092244

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