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Best matches for Südhof TC[au]:

Molecular Neuroscience in the 21<sup>st</sup> Century: A Personal Perspective. Südhof TC et al. Neuron. (2017)

Building Bridges through Science. Lissek T et al. Neuron. (2017)

Synaptic Neurexin Complexes: A Molecular Code for the Logic of Neural Circuits. Südhof TC et al. Cell. (2017)

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Items: 1 to 50 of 573


Towards an Understanding of Synapse Formation.

Südhof TC.

Neuron. 2018 Oct 24;100(2):276-293. doi: 10.1016/j.neuron.2018.09.040. Review.


Retinoic Acid Receptor RARα-Dependent Synaptic Signaling Mediates Homeostatic Synaptic Plasticity at the Inhibitory Synapses of Mouse Visual Cortex.

Zhong LR, Chen X, Park E, Südhof TC, Chen L.

J Neurosci. 2018 Dec 5;38(49):10454-10466. doi: 10.1523/JNEUROSCI.1133-18.2018. Epub 2018 Oct 24.


A central amygdala to zona incerta projection is required for acquisition and remote recall of conditioned fear memory.

Zhou M, Liu Z, Melin MD, Ng YH, Xu W, Südhof TC.

Nat Neurosci. 2018 Nov;21(11):1515-1519. doi: 10.1038/s41593-018-0248-4. Epub 2018 Oct 22.


Cbln2 and Cbln4 are expressed in distinct medial habenula-interpeduncular projections and contribute to different behavioral outputs.

Seigneur E, Polepalli JS, Südhof TC.

Proc Natl Acad Sci U S A. 2018 Oct 23;115(43):E10235-E10244. doi: 10.1073/pnas.1811086115. Epub 2018 Oct 4.


The fragile X mutation impairs homeostatic plasticity in human neurons by blocking synaptic retinoic acid signaling.

Zhang Z, Marro SG, Zhang Y, Arendt KL, Patzke C, Zhou B, Fair T, Yang N, Südhof TC, Wernig M, Chen L.

Sci Transl Med. 2018 Aug 1;10(452). pii: eaar4338. doi: 10.1126/scitranslmed.aar4338.


RIM-binding proteins recruit BK-channels to presynaptic release sites adjacent to voltage-gated Ca2+-channels.

Sclip A, Acuna C, Luo F, Südhof TC.

EMBO J. 2018 Aug 15;37(16). pii: e98637. doi: 10.15252/embj.201798637. Epub 2018 Jul 2.


Transdifferentiation of human adult peripheral blood T cells into neurons.

Tanabe K, Ang CE, Chanda S, Olmos VH, Haag D, Levinson DF, Südhof TC, Wernig M.

Proc Natl Acad Sci U S A. 2018 Jun 19;115(25):6470-6475. doi: 10.1073/pnas.1720273115. Epub 2018 Jun 4.


Deletion of LRRTM1 and LRRTM2 in adult mice impairs basal AMPA receptor transmission and LTP in hippocampal CA1 pyramidal neurons.

Bhouri M, Morishita W, Temkin P, Goswami D, Kawabe H, Brose N, Südhof TC, Craig AM, Siddiqui TJ, Malenka R.

Proc Natl Acad Sci U S A. 2018 Jun 5;115(23):E5382-E5389. doi: 10.1073/pnas.1803280115. Epub 2018 May 21.


Autism-associated neuroligin-4 mutation selectively impairs glycinergic synaptic transmission in mouse brainstem synapses.

Zhang B, Gokce O, Hale WD, Brose N, Südhof TC.

J Exp Med. 2018 Jun 4;215(6):1543-1553. doi: 10.1084/jem.20172162. Epub 2018 May 3.


The Neurobiology of Opioid Addiction and the Potential for Prevention Strategies.

Peltz G, Südhof TC.

JAMA. 2018 May 22;319(20):2071-2072. doi: 10.1001/jama.2018.3394. No abstract available.


Genetic Ablation of All Cerebellins Reveals Synapse Organizer Functions in Multiple Regions Throughout the Brain.

Seigneur E, Südhof TC.

J Neurosci. 2018 May 16;38(20):4774-4790. doi: 10.1523/JNEUROSCI.0360-18.2018. Epub 2018 Apr 24.


Structural Basis for Teneurin Function in Circuit-Wiring: A Toxin Motif at the Synapse.

Li J, Shalev-Benami M, Sando R, Jiang X, Kibrom A, Wang J, Leon K, Katanski C, Nazarko O, Lu YC, Südhof TC, Skiniotis G, Araç D.

Cell. 2018 Apr 19;173(3):735-748.e15. doi: 10.1016/j.cell.2018.03.036.


Building Bridges through Science.

Lissek T, Adams M, Adelman J, Ahissar E, Akaaboune M, Akil H, al'Absi M, Arain F, Arango-Lasprilla JC, Atasoy D, Avila J, Badawi A, Bading H, Baig AM, Baleriola J, Belmonte C, Bertocchi I, Betz H, Blakemore C, Blanke O, Boehm-Sturm P, Bonhoeffer T, Bonifazi P, Brose N, Campolongo P, Celikel T, Chang CC, Chang TY, Citri A, Cline HT, Cortes JM, Cullen K, Dean K, Delgado-Garcia JM, Desroches M, Disterhoft JF, Dowling JE, Draguhn A, El-Khamisy SF, El Manira A, Enam SA, Encinas JM, Erramuzpe A, Esteban JA, Fariñas I, Fischer E, Fukunaga I, Gabilondo I, Ganten D, Gidon A, Gomez-Esteban JC, Greengard P, Grinevich V, Gruart A, Guillemin R, Hariri AR, Hassan B, Häusser M, Hayashi Y, Hussain NK, Jabbar AA, Jaber M, Jahn R, Janahi EM, Kabbaj M, Kettenmann H, Kindt M, Knafo S, Köhr G, Komai S, Krugers H, Kuhn B, Ghazal NL, Larkum ME, London M, Lutz B, Matute C, Martinez-Millan L, Maroun M, McGaugh J, Moustafa AA, Nasim A, Nave KA, Neher E, Nikolich K, Outeiro T, Palmer LM, Penagarikano O, Perez-Otano I, Pfaff DW, Poucet B, Rahman AU, Ramos-Cabrer P, Rashidy-Pour A, Roberts RJ, Rodrigues S, Sanes JR, Schaefer AT, Segal M, Segev I, Shafqat S, Siddiqui NA, Soreq H, Soriano-García E, Spanagel R, Sprengel R, Stuart G, Südhof TC, Tønnesen J, Treviño M, Uthman BM, Venter JC, Verkhratsky A, Weiss C, Wiesel TN, Yaksi E, Yizhar O, Young LJ, Young P, Zawia NH, Zugaza JL, Hasan MT.

Neuron. 2017 Nov 15;96(4):730-735. doi: 10.1016/j.neuron.2017.09.028.


Synaptic Neurexin Complexes: A Molecular Code for the Logic of Neural Circuits.

Südhof TC.

Cell. 2017 Nov 2;171(4):745-769. doi: 10.1016/j.cell.2017.10.024. Review.


Molecular Neuroscience in the 21st Century: A Personal Perspective.

Südhof TC.

Neuron. 2017 Nov 1;96(3):536-541. doi: 10.1016/j.neuron.2017.10.005. Review.


Postsynaptic adhesion GPCR latrophilin-2 mediates target recognition in entorhinal-hippocampal synapse assembly.

Anderson GR, Maxeiner S, Sando R, Tsetsenis T, Malenka RC, Südhof TC.

J Cell Biol. 2017 Nov 6;216(11):3831-3846. doi: 10.1083/jcb.201703042. Epub 2017 Sep 28.


Exceptionally tight membrane-binding may explain the key role of the synaptotagmin-7 C2A domain in asynchronous neurotransmitter release.

Voleti R, Tomchick DR, Südhof TC, Rizo J.

Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):E8518-E8527. doi: 10.1073/pnas.1710708114. Epub 2017 Sep 18.


Efficient stimulus-secretion coupling at ribbon synapses requires RIM-binding protein tethering of L-type Ca2+ channels.

Luo F, Liu X, Südhof TC, Acuna C.

Proc Natl Acad Sci U S A. 2017 Sep 19;114(38):E8081-E8090. doi: 10.1073/pnas.1702991114. Epub 2017 Sep 5.


The primed SNARE-complexin-synaptotagmin complex for neuronal exocytosis.

Zhou Q, Zhou P, Wang AL, Wu D, Zhao M, Südhof TC, Brunger AT.

Nature. 2017 Aug 24;548(7668):420-425. doi: 10.1038/nature23484. Epub 2017 Aug 16.


Cerebellins are differentially expressed in selective subsets of neurons throughout the brain.

Seigneur E, Südhof TC.

J Comp Neurol. 2017 Oct 15;525(15):3286-3311. doi: 10.1002/cne.24278. Epub 2017 Jul 24.


IGF1-Dependent Synaptic Plasticity of Mitral Cells in Olfactory Memory during Social Learning.

Liu Z, Chen Z, Shang C, Yan F, Shi Y, Zhang J, Qu B, Han H, Wang Y, Li D, Südhof TC, Cao P.

Neuron. 2017 Jul 5;95(1):106-122.e5. doi: 10.1016/j.neuron.2017.06.015.


Unique versus Redundant Functions of Neuroligin Genes in Shaping Excitatory and Inhibitory Synapse Properties.

Chanda S, Hale WD, Zhang B, Wernig M, Südhof TC.

J Neurosci. 2017 Jul 19;37(29):6816-6836. doi: 10.1523/JNEUROSCI.0125-17.2017. Epub 2017 Jun 12.


Anatomical and Behavioral Investigation of C1ql3 in the Mouse Suprachiasmatic Nucleus.

Chew KS, Fernandez DC, Hattar S, Südhof TC, Martinelli DC.

J Biol Rhythms. 2017 Jun;32(3):222-236. doi: 10.1177/0748730417704766. Epub 2017 May 29.


Synaptotagmin-7-Mediated Asynchronous Release Boosts High-Fidelity Synchronous Transmission at a Central Synapse.

Luo F, Südhof TC.

Neuron. 2017 May 17;94(4):826-839.e3. doi: 10.1016/j.neuron.2017.04.020.


Generation of pure GABAergic neurons by transcription factor programming.

Yang N, Chanda S, Marro S, Ng YH, Janas JA, Haag D, Ang CE, Tang Y, Flores Q, Mall M, Wapinski O, Li M, Ahlenius H, Rubenstein JL, Chang HY, Buylla AA, Südhof TC, Wernig M.

Nat Methods. 2017 Jun;14(6):621-628. doi: 10.1038/nmeth.4291. Epub 2017 May 15.


Conditional Deletion of All Neurexins Defines Diversity of Essential Synaptic Organizer Functions for Neurexins.

Chen LY, Jiang M, Zhang B, Gokce O, Südhof TC.

Neuron. 2017 May 3;94(3):611-625.e4. doi: 10.1016/j.neuron.2017.04.011.


Myt1l safeguards neuronal identity by actively repressing many non-neuronal fates.

Mall M, Kareta MS, Chanda S, Ahlenius H, Perotti N, Zhou B, Grieder SD, Ge X, Drake S, Euong Ang C, Walker BM, Vierbuchen T, Fuentes DR, Brennecke P, Nitta KR, Jolma A, Steinmetz LM, Taipale J, Südhof TC, Wernig M.

Nature. 2017 Apr 13;544(7649):245-249. doi: 10.1038/nature21722. Epub 2017 Apr 5.


Postsynaptic synaptotagmins mediate AMPA receptor exocytosis during LTP.

Wu D, Bacaj T, Morishita W, Goswami D, Arendt KL, Xu W, Chen L, Malenka RC, Südhof TC.

Nature. 2017 Apr 20;544(7650):316-321. doi: 10.1038/nature21720. Epub 2017 Mar 29.


Correction: ELKS1 localizes the synaptic vesicle priming protein bMunc13-2 to a specific subset of active zones.

Kawabe H, Mitkovski M, Kaeser PS, Hirrlinger J, Opazo F, Nestvogel D, Kalla S, Fejtova A, Verrier SE, Bungers SR, Cooper BH, Varoqueaux F, Wang Y, Nehring RB, Gundelfinger ED, Rosenmund C, Rizzoli SO, Südhof TC, Rhee JS, Brose N.

J Cell Biol. 2017 Apr 3;216(4):1205. doi: 10.1083/jcb.20160608603092017c. Epub 2017 Mar 13. No abstract available.


ELKS1 localizes the synaptic vesicle priming protein bMunc13-2 to a specific subset of active zones.

Kawabe H, Mitkovski M, Kaeser PS, Hirrlinger J, Opazo F, Nestvogel D, Kalla S, Fejtova A, Verrier SE, Bungers SR, Cooper BH, Varoqueaux F, Wang Y, Nehring RB, Gundelfinger ED, Rosenmund C, Rizzoli SO, Südhof TC, Rhee JS, Brose N.

J Cell Biol. 2017 Apr 3;216(4):1143-1161. doi: 10.1083/jcb.201606086. Epub 2017 Mar 6. Erratum in: J Cell Biol. 2017 Apr 3;216(4):1205.


Carbonic anhydrase-related protein CA10 is an evolutionarily conserved pan-neurexin ligand.

Sterky FH, Trotter JH, Lee SJ, Recktenwald CV, Du X, Zhou B, Zhou P, Schwenk J, Fakler B, Südhof TC.

Proc Natl Acad Sci U S A. 2017 Feb 14;114(7):E1253-E1262. doi: 10.1073/pnas.1621321114. Epub 2017 Feb 1. Erratum in: Proc Natl Acad Sci U S A. 2017 Apr 4;114(14 ):E2984.


ApoE2, ApoE3, and ApoE4 Differentially Stimulate APP Transcription and Aβ Secretion.

Huang YA, Zhou B, Wernig M, Südhof TC.

Cell. 2017 Jan 26;168(3):427-441.e21. doi: 10.1016/j.cell.2016.12.044. Epub 2017 Jan 19.


Cell Biology and Pathophysiology of α-Synuclein.

Burré J, Sharma M, Südhof TC.

Cold Spring Harb Perspect Med. 2018 Mar 1;8(3). pii: a024091. doi: 10.1101/cshperspect.a024091. Review.


Modulation of excitation on parvalbumin interneurons by neuroligin-3 regulates the hippocampal network.

Polepalli JS, Wu H, Goswami D, Halpern CH, Südhof TC, Malenka RC.

Nat Neurosci. 2017 Feb;20(2):219-229. doi: 10.1038/nn.4471. Epub 2017 Jan 9.


Presynaptic Neuronal Pentraxin Receptor Organizes Excitatory and Inhibitory Synapses.

Lee SJ, Wei M, Zhang C, Maxeiner S, Pak C, Calado Botelho S, Trotter J, Sterky FH, Südhof TC.

J Neurosci. 2017 Feb 1;37(5):1062-1080. doi: 10.1523/JNEUROSCI.2768-16.2016. Epub 2016 Dec 16.


C-terminal domain of mammalian complexin-1 localizes to highly curved membranes.

Gong J, Lai Y, Li X, Wang M, Leitz J, Hu Y, Zhang Y, Choi UB, Cipriano D, Pfuetzner RA, Südhof TC, Yang X, Brunger AT, Diao J.

Proc Natl Acad Sci U S A. 2016 Nov 22;113(47):E7590-E7599. Epub 2016 Nov 7.


Developmental plasticity shapes synaptic phenotypes of autism-associated neuroligin-3 mutations in the calyx of Held.

Zhang B, Seigneur E, Wei P, Gokce O, Morgan J, Südhof TC.

Mol Psychiatry. 2017 Oct;22(10):1483-1491. doi: 10.1038/mp.2016.157. Epub 2016 Oct 11.


Neuroligins Are Selectively Essential for NMDAR Signaling in Cerebellar Stellate Interneurons.

Zhang B, Südhof TC.

J Neurosci. 2016 Aug 31;36(35):9070-83. doi: 10.1523/JNEUROSCI.1356-16.2016.


Truth in Science Publishing: A Personal Perspective.

Südhof TC.

PLoS Biol. 2016 Aug 26;14(8):e1002547. doi: 10.1371/journal.pbio.1002547. eCollection 2016 Aug.


How to Make an Active Zone: Unexpected Universal Functional Redundancy between RIMs and RIM-BPs.

Acuna C, Liu X, Südhof TC.

Neuron. 2016 Aug 17;91(4):792-807. doi: 10.1016/j.neuron.2016.07.042.


Single-cell RNAseq reveals cell adhesion molecule profiles in electrophysiologically defined neurons.

Földy C, Darmanis S, Aoto J, Malenka RC, Quake SR, Südhof TC.

Proc Natl Acad Sci U S A. 2016 Aug 30;113(35):E5222-31. doi: 10.1073/pnas.1610155113. Epub 2016 Aug 16.


Expression of C1ql3 in Discrete Neuronal Populations Controls Efferent Synapse Numbers and Diverse Behaviors.

Martinelli DC, Chew KS, Rohlmann A, Lum MY, Ressl S, Hattar S, Brunger AT, Missler M, Südhof TC.

Neuron. 2016 Sep 7;91(5):1034-1051. doi: 10.1016/j.neuron.2016.07.002. Epub 2016 Jul 28.


Cellular Taxonomy of the Mouse Striatum as Revealed by Single-Cell RNA-Seq.

Gokce O, Stanley GM, Treutlein B, Neff NF, Camp JG, Malenka RC, Rothwell PE, Fuccillo MV, Südhof TC, Quake SR.

Cell Rep. 2016 Jul 26;16(4):1126-1137. doi: 10.1016/j.celrep.2016.06.059. Epub 2016 Jul 14.


FoxO3 regulates neuronal reprogramming of cells from postnatal and aging mice.

Ahlenius H, Chanda S, Webb AE, Yousif I, Karmazin J, Prusiner SB, Brunet A, Südhof TC, Wernig M.

Proc Natl Acad Sci U S A. 2016 Jul 26;113(30):8514-9. doi: 10.1073/pnas.1607079113. Epub 2016 Jul 11.


Extended Synaptotagmin (ESyt) Triple Knock-Out Mice Are Viable and Fertile without Obvious Endoplasmic Reticulum Dysfunction.

Sclip A, Bacaj T, Giam LR, Südhof TC.

PLoS One. 2016 Jun 27;11(6):e0158295. doi: 10.1371/journal.pone.0158295. eCollection 2016.


Conditional ablation of neuroligin-1 in CA1 pyramidal neurons blocks LTP by a cell-autonomous NMDA receptor-independent mechanism.

Jiang M, Polepalli J, Chen LY, Zhang B, Südhof TC, Malenka RC.

Mol Psychiatry. 2017 Mar;22(3):375-383. doi: 10.1038/mp.2016.80. Epub 2016 May 24.


The conditional KO approach: Cre/Lox technology in human neurons.

Patzke C, Südhof TC.

Rare Dis. 2016 Feb 18;4(1):e1131884. doi: 10.1080/21675511.2015.1131884. eCollection 2016.


Conditional deletion of L1CAM in human neurons impairs both axonal and dendritic arborization and action potential generation.

Patzke C, Acuna C, Giam LR, Wernig M, Südhof TC.

J Exp Med. 2016 Apr 4;213(4):499-515. doi: 10.1084/jem.20150951. Epub 2016 Mar 21.


Autism-associated SHANK3 haploinsufficiency causes Ih channelopathy in human neurons.

Yi F, Danko T, Botelho SC, Patzke C, Pak C, Wernig M, Südhof TC.

Science. 2016 May 6;352(6286):aaf2669. doi: 10.1126/science.aaf2669. Epub 2016 Mar 10.


How to make a synaptic ribbon: RIBEYE deletion abolishes ribbons in retinal synapses and disrupts neurotransmitter release.

Maxeiner S, Luo F, Tan A, Schmitz F, Südhof TC.

EMBO J. 2016 May 17;35(10):1098-114. doi: 10.15252/embj.201592701. Epub 2016 Feb 29.

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