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Items: 1 to 50 of 160

1.

Mammalian Hbs1L deficiency causes congenital anomalies and developmental delay associated with Pelota depletion and 80S monosome accumulation.

O'Connell AE, Gerashchenko MV, O'Donohue MF, Rosen SM, Huntzinger E, Gleeson D, Galli A, Ryder E, Cao S, Murphy Q, Kazerounian S, Morton SU, Schmitz-Abe K, Gladyshev VN, Gleizes PE, Séraphin B, Agrawal PB.

PLoS Genet. 2019 Feb 1;15(2):e1007917. doi: 10.1371/journal.pgen.1007917. eCollection 2019 Feb.

2.

A unique surface on Pat1 C-terminal domain directly interacts with Dcp2 decapping enzyme and Xrn1 5'-3' mRNA exonuclease in yeast.

Charenton C, Gaudon-Plesse C, Fourati Z, Taverniti V, Back R, Kolesnikova O, Séraphin B, Graille M.

Proc Natl Acad Sci U S A. 2017 Nov 7;114(45):E9493-E9501. doi: 10.1073/pnas.1711680114. Epub 2017 Oct 24.

3.

Structures and Activities of the Elongator Complex and Its Cofactors.

Kolaj-Robin O, Séraphin B.

Enzymes. 2017;41:117-149. doi: 10.1016/bs.enz.2017.03.001. Epub 2017 Apr 12.

PMID:
28601220
4.

Crystal structure of U2 snRNP SF3b components: Hsh49p in complex with Cus1p-binding domain.

van Roon AM, Oubridge C, Obayashi E, Sposito B, Newman AJ, Séraphin B, Nagai K.

RNA. 2017 Jun;23(6):968-981. doi: 10.1261/rna.059378.116. Epub 2017 Mar 27.

5.

Architecture of the yeast Elongator complex.

Dauden MI, Kosinski J, Kolaj-Robin O, Desfosses A, Ori A, Faux C, Hoffmann NA, Onuma OF, Breunig KD, Beck M, Sachse C, Séraphin B, Glatt S, Müller CW.

EMBO Rep. 2017 Feb;18(2):264-279. doi: 10.15252/embr.201643353. Epub 2016 Dec 14.

6.

Structure of the active form of Dcp1-Dcp2 decapping enzyme bound to m7GDP and its Edc3 activator.

Charenton C, Taverniti V, Gaudon-Plesse C, Back R, Séraphin B, Graille M.

Nat Struct Mol Biol. 2016 Nov;23(11):982-986. doi: 10.1038/nsmb.3300. Epub 2016 Oct 3.

PMID:
27694841
7.

Acetylation-Dependent Control of Global Poly(A) RNA Degradation by CBP/p300 and HDAC1/2.

Sharma S, Poetz F, Bruer M, Ly-Hartig TB, Schott J, Séraphin B, Stoecklin G.

Mol Cell. 2016 Sep 15;63(6):927-38. doi: 10.1016/j.molcel.2016.08.030.

8.

Structural basis for tRNA modification by Elp3 from Dehalococcoides mccartyi.

Glatt S, Zabel R, Kolaj-Robin O, Onuma OF, Baudin F, Graziadei A, Taverniti V, Lin TY, Baymann F, Seraphin B, Breunig KD, Müller CW.

Nat Struct Mol Biol. 2016 Sep;23(9):794-802. doi: 10.1038/nsmb.3265. Epub 2016 Jul 25.

9.

BTG2 bridges PABPC1 RNA-binding domains and CAF1 deadenylase to control cell proliferation.

Stupfler B, Birck C, Séraphin B, Mauxion F.

Nat Commun. 2016 Feb 25;7:10811. doi: 10.1038/ncomms10811.

10.

Gbp2 interacts with THO/TREX through a novel type of RRM domain.

Martínez-Lumbreras S, Taverniti V, Zorrilla S, Séraphin B, Pérez-Cañadillas JM.

Nucleic Acids Res. 2016 Jan 8;44(1):437-48. doi: 10.1093/nar/gkv1303. Epub 2015 Nov 23.

11.

Loss of the scavenger mRNA decapping enzyme DCPS causes syndromic intellectual disability with neuromuscular defects.

Ng CK, Shboul M, Taverniti V, Bonnard C, Lee H, Eskin A, Nelson SF, Al-Raqad M, Altawalbeh S, Séraphin B, Reversade B.

Hum Mol Genet. 2015 Jun 1;24(11):3163-71. doi: 10.1093/hmg/ddv067. Epub 2015 Feb 24.

12.

Structure of the Elongator cofactor complex Kti11/Kti13 provides insight into the role of Kti13 in Elongator-dependent tRNA modification.

Kolaj-Robin O, McEwen AG, Cavarelli J, Séraphin B.

FEBS J. 2015 Mar;282(5):819-33. doi: 10.1111/febs.13199. Epub 2015 Feb 4.

13.

Elimination of cap structures generated by mRNA decay involves the new scavenger mRNA decapping enzyme Aph1/FHIT together with DcpS.

Taverniti V, Séraphin B.

Nucleic Acids Res. 2015 Jan;43(1):482-92. doi: 10.1093/nar/gku1251. Epub 2014 Nov 28.

14.

Quantification of pre-mRNA escape rate and synergy in splicing.

Bonde MM, Voegeli S, Baudrimont A, Séraphin B, Becskei A.

Nucleic Acids Res. 2014 Nov 10;42(20):12847-60. doi: 10.1093/nar/gku1014. Epub 2014 Oct 28.

15.

A novel protein-protein interaction in the RES (REtention and Splicing) complex.

Tripsianes K, Friberg A, Barrandon C, Brooks M, van Tilbeurgh H, Seraphin B, Sattler M.

J Biol Chem. 2014 Oct 10;289(41):28640-50. doi: 10.1074/jbc.M114.592311. Epub 2014 Aug 26.

16.

The C-terminal domain from S. cerevisiae Pat1 displays two conserved regions involved in decapping factor recruitment.

Fourati Z, Kolesnikova O, Back R, Keller J, Charenton C, Taverniti V, Plesse CG, Lazar N, Durand D, van Tilbeurgh H, Séraphin B, Graille M.

PLoS One. 2014 May 15;9(5):e96828. doi: 10.1371/journal.pone.0096828. eCollection 2014.

17.

Long open reading frame transcripts escape nonsense-mediated mRNA decay in yeast.

Decourty L, Doyen A, Malabat C, Frachon E, Rispal D, Séraphin B, Feuerbach F, Jacquier A, Saveanu C.

Cell Rep. 2014 Feb 27;6(4):593-8. doi: 10.1016/j.celrep.2014.01.025. Epub 2014 Feb 13.

18.

Dom34-Hbs1 mediated dissociation of inactive 80S ribosomes promotes restart of translation after stress.

van den Elzen AM, Schuller A, Green R, Séraphin B.

EMBO J. 2014 Feb 3;33(3):265-76. doi: 10.1002/embj.201386123. Epub 2014 Jan 14.

19.

Structure and RNA-binding properties of the Not1-Not2-Not5 module of the yeast Ccr4-Not complex.

Bhaskar V, Roudko V, Basquin J, Sharma K, Urlaub H, Séraphin B, Conti E.

Nat Struct Mol Biol. 2013 Nov;20(11):1281-8. doi: 10.1038/nsmb.2686. Epub 2013 Oct 13.

PMID:
24121231
20.

Identification of the Rps28 binding motif from yeast Edc3 involved in the autoregulatory feedback loop controlling RPS28B mRNA decay.

Kolesnikova O, Back R, Graille M, Séraphin B.

Nucleic Acids Res. 2013 Nov;41(20):9514-23. doi: 10.1093/nar/gkt607. Epub 2013 Aug 16.

21.

Rapid screening of yeast mutants with reporters identifies new splicing phenotypes.

Dreumont N, Séraphin B.

FEBS J. 2013 Jun;280(11):2712-26. doi: 10.1111/febs.12277. Epub 2013 May 9.

22.

Intracellular ribonucleases involved in transcript processing and decay: precision tools for RNA.

Arraiano CM, Mauxion F, Viegas SC, Matos RG, Séraphin B.

Biochim Biophys Acta. 2013 Jun-Jul;1829(6-7):491-513. doi: 10.1016/j.bbagrm.2013.03.009. Epub 2013 Mar 29. Review.

PMID:
23545199
23.

C2ORF29/CNOT11 and CNOT10 form a new module of the CCR4-NOT complex.

Mauxion F, Prève B, Séraphin B.

RNA Biol. 2013 Feb;10(2):267-76. doi: 10.4161/rna.23065. Epub 2012 Dec 11.

24.

Surveillance pathways rescuing eukaryotic ribosomes lost in translation.

Graille M, Séraphin B.

Nat Rev Mol Cell Biol. 2012 Nov;13(11):727-35. doi: 10.1038/nrm3457. Epub 2012 Oct 17. Review.

PMID:
23072885
25.

Rbg1-Tma46 dimer structure reveals new functional domains and their role in polysome recruitment.

Francis SM, Gas ME, Daugeron MC, Bravo J, Séraphin B.

Nucleic Acids Res. 2012 Nov;40(21):11100-14. doi: 10.1093/nar/gks867. Epub 2012 Sep 23.

26.

Extensive degradation of RNA precursors by the exosome in wild-type cells.

Gudipati RK, Xu Z, Lebreton A, Séraphin B, Steinmetz LM, Jacquier A, Libri D.

Mol Cell. 2012 Nov 9;48(3):409-21. doi: 10.1016/j.molcel.2012.08.018. Epub 2012 Sep 20.

27.

Architecture of the nuclease module of the yeast Ccr4-not complex: the Not1-Caf1-Ccr4 interaction.

Basquin J, Roudko VV, Rode M, Basquin C, Séraphin B, Conti E.

Mol Cell. 2012 Oct 26;48(2):207-18. doi: 10.1016/j.molcel.2012.08.014. Epub 2012 Sep 6.

28.

Elongator: transcriptional or translational regulator?

Glatt S, Séraphin B, Müller CW.

Transcription. 2012 Nov-Dec;3(6):273-6. doi: 10.4161/trns.21525. Epub 2012 Aug 14.

29.

Microbial proteomics: the quiet revolution.

Séraphin B, Hettich R.

Curr Opin Microbiol. 2012 Jun;15(3):348-50. doi: 10.1016/j.mib.2012.05.004. Epub 2012 May 23. No abstract available.

PMID:
22632759
30.

The Elongator subcomplex Elp456 is a hexameric RecA-like ATPase.

Glatt S, Létoquart J, Faux C, Taylor NM, Séraphin B, Müller CW.

Nat Struct Mol Biol. 2012 Feb 19;19(3):314-20. doi: 10.1038/nsmb.2234.

PMID:
22343726
31.

Cotranscriptional spliceosome assembly and splicing are independent of the Prp40p WW domain.

Görnemann J, Barrandon C, Hujer K, Rutz B, Rigaut G, Kotovic KM, Faux C, Neugebauer KM, Séraphin B.

RNA. 2011 Dec;17(12):2119-29. doi: 10.1261/rna.02646811. Epub 2011 Oct 21.

32.

Catalytic properties of the eukaryotic exosome.

Chlebowski A, Tomecki R, Gas López ME, Séraphin B, Dziembowski A.

Adv Exp Med Biol. 2011;702:63-78. doi: 10.1007/978-1-4419-7841-7_6.

PMID:
21713678
33.

Structural and functional analysis of Nro1/Ett1: a protein involved in translation termination in S. cerevisiae and in O2-mediated gene control in S. pombe.

Rispal D, Henri J, van Tilbeurgh H, Graille M, Séraphin B.

RNA. 2011 Jul;17(7):1213-24. doi: 10.1261/rna.2697111. Epub 2011 May 24.

34.

Strategies for the structural analysis of multi-protein complexes: lessons from the 3D-Repertoire project.

Collinet B, Friberg A, Brooks MA, van den Elzen T, Henriot V, Dziembowski A, Graille M, Durand D, Leulliot N, Saint André C, Lazar N, Sattler M, Séraphin B, van Tilbeurgh H.

J Struct Biol. 2011 Aug;175(2):147-58. doi: 10.1016/j.jsb.2011.03.018. Epub 2011 Apr 2.

PMID:
21463689
35.

Dissection of Dom34-Hbs1 reveals independent functions in two RNA quality control pathways.

van den Elzen AM, Henri J, Lazar N, Gas ME, Durand D, Lacroute F, Nicaise M, van Tilbeurgh H, Séraphin B, Graille M.

Nat Struct Mol Biol. 2010 Dec;17(12):1446-52. doi: 10.1038/nsmb.1963. Epub 2010 Nov 21.

PMID:
21102444
36.

The highly conserved eukaryotic DRG factors are required for efficient translation in a manner redundant with the putative RNA helicase Slh1.

Daugeron MC, Prouteau M, Lacroute F, Séraphin B.

Nucleic Acids Res. 2011 Mar;39(6):2221-33. doi: 10.1093/nar/gkq898. Epub 2010 Nov 13.

37.

Systematic bioinformatics and experimental validation of yeast complexes reduces the rate of attrition during structural investigations.

Brooks MA, Gewartowski K, Mitsiki E, Létoquart J, Pache RA, Billier Y, Bertero M, Corréa M, Czarnocki-Cieciura M, Dadlez M, Henriot V, Lazar N, Delbos L, Lebert D, Piwowarski J, Rochaix P, Böttcher B, Serrano L, Séraphin B, van Tilbeurgh H, Aloy P, Perrakis A, Dziembowski A.

Structure. 2010 Sep 8;18(9):1075-82. doi: 10.1016/j.str.2010.08.001.

38.

Twins take the job.

Gas ME, Séraphin B.

EMBO J. 2010 Jul 21;29(14):2260-1. doi: 10.1038/emboj.2010.148. No abstract available.

39.

Structural and functional insights into Saccharomyces cerevisiae Tpa1, a putative prolylhydroxylase influencing translation termination and transcription.

Henri J, Rispal D, Bayart E, van Tilbeurgh H, Séraphin B, Graille M.

J Biol Chem. 2010 Oct 1;285(40):30767-78. doi: 10.1074/jbc.M110.106864. Epub 2010 Jul 14.

40.

Catalytic properties of the eukaryotic exosome.

Chlebowski A, Tomecki R, López ME, Séraphin B, Dziembowski A.

Adv Exp Med Biol. 2010;702:63-78. Review.

PMID:
21618875
41.

BTG/TOB factors impact deadenylases.

Mauxion F, Chen CY, Séraphin B, Shyu AB.

Trends Biochem Sci. 2009 Dec;34(12):640-7. doi: 10.1016/j.tibs.2009.07.008. Epub 2009 Oct 12. Review.

42.

Endonucleolytic RNA cleavage by a eukaryotic exosome.

Lebreton A, Tomecki R, Dziembowski A, Séraphin B.

Nature. 2008 Dec 18;456(7224):993-6. doi: 10.1038/nature07480. Epub 2008 Dec 7.

43.

Structure of the yeast Pml1 splicing factor and its integration into the RES complex.

Brooks MA, Dziembowski A, Quevillon-Cheruel S, Henriot V, Faux C, van Tilbeurgh H, Séraphin B.

Nucleic Acids Res. 2009 Jan;37(1):129-43. doi: 10.1093/nar/gkn894. Epub 2008 Nov 25.

44.

Regulation of ARE transcript 3' end processing by the yeast Cth2 mRNA decay factor.

Prouteau M, Daugeron MC, Séraphin B.

EMBO J. 2008 Nov 19;27(22):2966-76. doi: 10.1038/emboj.2008.212. Epub 2008 Oct 16.

45.

Challenges and rewards of interaction proteomics.

Wodak SJ, Pu S, Vlasblom J, Séraphin B.

Mol Cell Proteomics. 2009 Jan;8(1):3-18. doi: 10.1074/mcp.R800014-MCP200. Epub 2008 Sep 17. Review.

46.

Futile cycle of transcription initiation and termination modulates the response to nucleotide shortage in S. cerevisiae.

Thiebaut M, Colin J, Neil H, Jacquier A, Séraphin B, Lacroute F, Libri D.

Mol Cell. 2008 Sep 5;31(5):671-82. doi: 10.1016/j.molcel.2008.08.010.

47.

EJCs at the heart of translational control.

Le Hir H, Séraphin B.

Cell. 2008 Apr 18;133(2):213-6. doi: 10.1016/j.cell.2008.04.002. Review.

48.

The BTG2 protein is a general activator of mRNA deadenylation.

Mauxion F, Faux C, Séraphin B.

EMBO J. 2008 Apr 9;27(7):1039-48. doi: 10.1038/emboj.2008.43. Epub 2008 Mar 13.

49.

Exosome-mediated quality control: substrate recruitment and molecular activity.

Lebreton A, Séraphin B.

Biochim Biophys Acta. 2008 Sep;1779(9):558-65. doi: 10.1016/j.bbagrm.2008.02.003. Epub 2008 Feb 14. Review.

50.

Complex assembly mechanism and an RNA-binding mode of the human p14-SF3b155 spliceosomal protein complex identified by NMR solution structure and functional analyses.

Kuwasako K, Dohmae N, Inoue M, Shirouzu M, Taguchi S, Güntert P, Séraphin B, Muto Y, Yokoyama S.

Proteins. 2008 Jun;71(4):1617-36.

PMID:
18076038

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