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Items: 1 to 50 of 55

1.

Transcriptional profiling of the murine intervertebral disc and age-associated changes in the nucleus pulposus.

Veras MA, McCann MR, Tenn NA, Séguin CA.

Connect Tissue Res. 2020 Jan;61(1):63-81. doi: 10.1080/03008207.2019.1665034. Epub 2019 Oct 10.

PMID:
31597481
2.

Loss of ENT1 increases cell proliferation in the annulus fibrosus of the intervertebral disc.

Veras MA, Tenn NA, Kuljanin M, Lajoie GA, Hammond JR, Dixon SJ, Séguin CA.

J Cell Physiol. 2019 Aug;234(8):13705-13719. doi: 10.1002/jcp.28051. Epub 2019 Jan 11.

PMID:
31010267
3.

Ectopic spinal calcification associated with diffuse idiopathic skeletal hyperostosis (DISH): A quantitative micro-ct analysis.

Fournier DE, Norley CJD, Pollmann SI, Bailey CS, Al Helal F, Willmore KE, Holdsworth DW, Dixon SJ, Séguin CA.

J Orthop Res. 2019 Mar;37(3):717-726. doi: 10.1002/jor.24247. Epub 2019 Feb 28.

PMID:
30756413
4.

Latest advances in intervertebral disc development and progenitor cells.

Séguin CA, Chan D, Dahia CL, Gazit Z.

JOR Spine. 2018 Sep;1(3):e1030. doi: 10.1002/jsp2.1030. Epub 2018 Aug 28. Review.

5.

Impaired Annulus Fibrosus Development and Vertebral Fusion Cause Severe Scoliosis in Mice with Deficiency of c-Jun NH2-Terminal Kinases 1 and 2.

Ulici V, Kelley KL, Longobardi L, McNulty MA, Livingston EW, Bateman TA, Séguin CA, Louer CR, Loeser RF.

Am J Pathol. 2019 Apr;189(4):868-885. doi: 10.1016/j.ajpath.2018.12.010. Epub 2019 Jan 19.

PMID:
30664861
6.

Ciliary parathyroid hormone signaling activates transforming growth factor-β to maintain intervertebral disc homeostasis during aging.

Zheng L, Cao Y, Ni S, Qi H, Ling Z, Xu X, Zou X, Wu T, Deng R, Hu B, Gao B, Chen H, Li Y, Zhu J, Tintani F, Demehri S, Jain A, Kebaish KM, Liao S, Séguin CA, Crane JL, Wan M, Lu H, Sponseller PD, Riley LH 3rd, Zhou X, Hu J, Cao X.

Bone Res. 2018 Jul 18;6:21. doi: 10.1038/s41413-018-0022-y. eCollection 2018.

7.

Histological and reference system for the analysis of mouse intervertebral disc.

Tam V, Chan WCW, Leung VYL, Cheah KSE, Cheung KMC, Sakai D, McCann MR, Bedore J, Séguin CA, Chan D.

J Orthop Res. 2018 Jan;36(1):233-243. doi: 10.1002/jor.23637. Epub 2017 Jul 18.

8.

Mechanosignaling activation of TGFβ maintains intervertebral disc homeostasis.

Bian Q, Ma L, Jain A, Crane JL, Kebaish K, Wan M, Zhang Z, Edward Guo X, Sponseller PD, Séguin CA, Riley LH, Wang Y, Cao X.

Bone Res. 2017 Mar 21;5:17008. doi: 10.1038/boneres.2017.8. eCollection 2017.

9.

Paraspinal Muscle Passive Stiffness Remodels in Direct Response to Spine Stiffness: A Study Using the ENT1-Deficient Mouse.

Gsell KY, Zwambag DP, Fournier DE, Séguin CA, Brown SHM.

Spine (Phila Pa 1976). 2017 Oct 1;42(19):1440-1446. doi: 10.1097/BRS.0000000000002132.

PMID:
28240653
10.

Connexin43 Mutant Patient-Derived Induced Pluripotent Stem Cells Exhibit Altered Differentiation Potential.

Esseltine JL, Shao Q, Brooks C, Sampson J, Betts DH, Séguin CA, Laird DW.

J Bone Miner Res. 2017 Jun;32(6):1368-1385. doi: 10.1002/jbmr.3098. Epub 2017 Apr 5.

11.

Whole-body vibration of mice induces progressive degeneration of intervertebral discs associated with increased expression of Il-1β and multiple matrix degrading enzymes.

McCann MR, Veras MA, Yeung C, Lalli G, Patel P, Leitch KM, Holdsworth DW, Dixon SJ, Séguin CA.

Osteoarthritis Cartilage. 2017 May;25(5):779-789. doi: 10.1016/j.joca.2017.01.004. Epub 2017 Jan 16.

12.

Whole-body vibration of mice induces articular cartilage degeneration with minimal changes in subchondral bone.

McCann MR, Yeung C, Pest MA, Ratneswaran A, Pollmann SI, Holdsworth DW, Beier F, Dixon SJ, Séguin CA.

Osteoarthritis Cartilage. 2017 May;25(5):770-778. doi: 10.1016/j.joca.2016.11.001. Epub 2016 Nov 10.

13.

C57BL/6 mice are resistant to joint degeneration induced by whole-body vibration.

Kerr GJ, McCann MR, Branch JK, Ratneswaran A, Pest MA, Holdsworth DW, Beier F, Dixon SJ, Séguin CA.

Osteoarthritis Cartilage. 2017 Mar;25(3):421-425. doi: 10.1016/j.joca.2016.09.020. Epub 2016 Oct 6.

14.

Small-Molecule Induction of Canine Embryonic Stem Cells Toward Naïve Pluripotency.

Tobias IC, Brooks CR, Teichroeb JH, Villagómez DA, Hess DA, Séguin CA, Betts DH.

Stem Cells Dev. 2016 Aug 15;25(16):1208-22. doi: 10.1089/scd.2016.0103. Epub 2016 Jul 28.

PMID:
27392793
15.

Notochord Cells in Intervertebral Disc Development and Degeneration.

McCann MR, Séguin CA.

J Dev Biol. 2016 Mar;4(1). pii: 3. doi: 10.3390/jdb4010003. Epub 2016 Jan 21.

16.

Disruption of biomineralization pathways in spinal tissues of a mouse model of diffuse idiopathic skeletal hyperostosis.

Ii H, Warraich S, Tenn N, Quinonez D, Holdsworth DW, Hammond JR, Dixon SJ, Séguin CA.

Bone. 2016 Sep;90:37-49. doi: 10.1016/j.bone.2016.05.008. Epub 2016 May 27.

PMID:
27237608
17.

Decoding the intervertebral disc: Unravelling the complexities of cell phenotypes and pathways associated with degeneration and mechanotransduction.

Kerr GJ, Veras MA, Kim MK, Séguin CA.

Semin Cell Dev Biol. 2017 Feb;62:94-103. doi: 10.1016/j.semcdb.2016.05.008. Epub 2016 May 18. Review.

PMID:
27208724
18.

Targeting the annulus fibrosus of the intervertebral disc: Col1a2-Cre(ER)T mice show specific activity of Cre recombinase in the outer annulus fibrosus.

Bedore J, Quesnel K, Quinonez D, Séguin CA, Leask A.

J Cell Commun Signal. 2016 Jun;10(2):137-42. doi: 10.1007/s12079-016-0329-7. Epub 2016 May 12.

19.

Repeated exposure to high-frequency low-amplitude vibration induces degeneration of murine intervertebral discs and knee joints.

McCann MR, Patel P, Pest MA, Ratneswaran A, Lalli G, Beaucage KL, Backler GB, Kamphuis MP, Esmail Z, Lee J, Barbalinardo M, Mort JS, Holdsworth DW, Beier F, Dixon SJ, Séguin CA.

Arthritis Rheumatol. 2015 May;67(8):2164-75. doi: 10.1002/art.39154.

20.

Proteomic signature of the murine intervertebral disc.

McCann MR, Patel P, Frimpong A, Xiao Y, Siqueira WL, Séguin CA.

PLoS One. 2015 Feb 17;10(2):e0117807. doi: 10.1371/journal.pone.0117807. eCollection 2015.

21.

Investigating microenvironmental regulation of human chordoma cell behaviour.

Patel P, Brooks C, Seneviratne A, Hess DA, Séguin CA.

PLoS One. 2014 Dec 26;9(12):e115909. doi: 10.1371/journal.pone.0115909. eCollection 2014.

22.

Targeting the extracellular matrix: matricellular proteins regulate cell-extracellular matrix communication within distinct niches of the intervertebral disc.

Bedore J, Leask A, Séguin CA.

Matrix Biol. 2014 Jul;37:124-30. doi: 10.1016/j.matbio.2014.05.005. Epub 2014 May 27. Review.

23.

Impaired intervertebral disc development and premature disc degeneration in mice with notochord-specific deletion of CCN2.

Bedore J, Sha W, McCann MR, Liu S, Leask A, Séguin CA.

Arthritis Rheum. 2013 Oct;65(10):2634-44. doi: 10.1002/art.38075.

24.

Acute vibration induces transient expression of anabolic genes in the murine intervertebral disc.

McCann MR, Patel P, Beaucage KL, Xiao Y, Bacher C, Siqueira WL, Holdsworth DW, Dixon SJ, Séguin CA.

Arthritis Rheum. 2013 Jul;65(7):1853-64. doi: 10.1002/art.37979.

25.

Loss of equilibrative nucleoside transporter 1 in mice leads to progressive ectopic mineralization of spinal tissues resembling diffuse idiopathic skeletal hyperostosis in humans.

Warraich S, Bone DB, Quinonez D, Ii H, Choi DS, Holdsworth DW, Drangova M, Dixon SJ, Séguin CA, Hammond JR.

J Bone Miner Res. 2013 May;28(5):1135-49. doi: 10.1002/jbmr.1826.

26.

Tracing notochord-derived cells using a Noto-cre mouse: implications for intervertebral disc development.

McCann MR, Tamplin OJ, Rossant J, Séguin CA.

Dis Model Mech. 2012 Jan;5(1):73-82. doi: 10.1242/dmm.008128. Epub 2011 Oct 25.

27.

BMP signaling induces visceral endoderm differentiation of XEN cells and parietal endoderm.

Paca A, Séguin CA, Clements M, Ryczko M, Rossant J, Rodriguez TA, Kunath T.

Dev Biol. 2012 Jan 1;361(1):90-102. doi: 10.1016/j.ydbio.2011.10.013. Epub 2011 Oct 14.

28.

Exploiting notochord cells for stem cell-based regeneration of the intervertebral disc.

McCann MR, Bacher CA, Séguin CA.

J Cell Commun Signal. 2011 Mar;5(1):39-43. doi: 10.1007/s12079-010-0116-9. Epub 2011 Jan 16.

29.

Isolation of human iPS cells using EOS lentiviral vectors to select for pluripotency.

Hotta A, Cheung AY, Farra N, Vijayaragavan K, Séguin CA, Draper JS, Pasceri P, Maksakova IA, Mager DL, Rossant J, Bhatia M, Ellis J.

Nat Methods. 2009 May;6(5):370-6. doi: 10.1038/nmeth.1325. Epub 2009 Apr 26.

PMID:
19404254
30.

Establishment of endoderm progenitors by SOX transcription factor expression in human embryonic stem cells.

Séguin CA, Draper JS, Nagy A, Rossant J.

Cell Stem Cell. 2008 Aug 7;3(2):182-95. doi: 10.1016/j.stem.2008.06.018.

31.

TNF-alpha induces MMP2 gelatinase activity and MT1-MMP expression in an in vitro model of nucleus pulposus tissue degeneration.

Séguin CA, Pilliar RM, Madri JA, Kandel RA.

Spine (Phila Pa 1976). 2008 Feb 15;33(4):356-65. doi: 10.1097/BRS.0b013e3181642a5e.

PMID:
18277865
32.

Differential regulation of matrix degrading enzymes in a TNFalpha-induced model of nucleus pulposus tissue degeneration.

Séguin CA, Bojarski M, Pilliar RM, Roughley PJ, Kandel RA.

Matrix Biol. 2006 Sep;25(7):409-18. Epub 2006 Aug 23.

PMID:
16934445
33.

Formation of a nucleus pulposus-cartilage endplate construct in vitro.

Hamilton DJ, Séguin CA, Wang J, Pilliar RM, Kandel RA; BioEngineering of Skeletal Tissues Team.

Biomaterials. 2006 Jan;27(3):397-405. Epub 2005 Sep 2.

PMID:
16139883
34.

Tumor necrosis factor-alpha modulates matrix production and catabolism in nucleus pulposus tissue.

Séguin CA, Pilliar RM, Roughley PJ, Kandel RA.

Spine (Phila Pa 1976). 2005 Sep 1;30(17):1940-8.

PMID:
16135983
35.

Tissue engineered nucleus pulposus tissue formed on a porous calcium polyphosphate substrate.

Séguin CA, Grynpas MD, Pilliar RM, Waldman SD, Kandel RA.

Spine (Phila Pa 1976). 2004 Jun 15;29(12):1299-306; discussion 1306-7.

PMID:
15187628
36.
37.

[Medical anthropology].

Seguín CA.

Acta Psiquiatr Psicol Am Lat. 1987 Mar;33(1):60-2. Spanish.

PMID:
3661227
38.

Letter: Therapeutic Eros.

Seguin CA.

Am J Psychiatry. 1975 Nov;132(11):1222-3. No abstract available.

PMID:
1166908
39.

[Prospects of psychiatric research in Latin America].

Seguin CA, Mariategui J.

Acta Psiquiatr Psicol Am Lat. 1975 Sep-Dec;31(3-4):175-85. Spanish.

PMID:
1217512
40.

[Introduction to folkloric psychiatry].

Seguin CA.

Acta Psiquiatr Psicol Am Lat. 1974 Oct;20(5):301-36. Review. Spanish. No abstract available.

PMID:
4618026
41.

What folklore psychotherapy can teach us.

Seguin CA.

Psychother Psychosom. 1974;24(4-6):293-302. No abstract available.

PMID:
4449942
42.

The "individual" space.

Seguin CA.

Int J Neuropsychiatry. 1967 Apr;3(2):108-17. No abstract available.

PMID:
5339862
43.

Attitudes of medical students.

Seguín CA.

Am J Psychiatry. 1966 Jun;122(12):1449-50. No abstract available.

PMID:
5932064
44.

GROUPS IN MEDICAL EDUCATION.

SEGUIN CA.

J Med Educ. 1965 Mar;40:281-5. No abstract available.

PMID:
14254293
45.

THE THEORY AND PRACTICE OF PSYCHIATRY IN PERU.

SEGUIN CA.

Am J Psychother. 1964 Apr;18:188-211. No abstract available.

PMID:
14138864
46.

[PSYCHOLOGY IN THE TEACHING OF PSYCHOLOGY].

SEGUIN CA.

An Fac Med Lima. 1963 Dec;46:570-86. Spanish. No abstract available.

PMID:
14156032
47.

[Basic forms of interpersonal relationships and their parallels in psychotherapy].

SEGUIN CA.

Z Psychother Med Psychol. 1963 Jan;13:1-11. German. No abstract available.

PMID:
13987712
48.

On approaching an aspect of the psychology of the ego-in-the world.

SEGUIN CA, PONCE OV.

Acta Psychother Psychosom. 1961;9:55-65. No abstract available.

PMID:
13749701
49.

Migration and psychosomatic disadaptation.

SEGUIN CA.

Psychosom Med. 1956 Sep-Oct;18(5):404-9. No abstract available.

PMID:
13370705
50.

Language and psychotherapy.

SEGUIN CA.

J Nerv Ment Dis. 1955 Jun;121(6):564-7. No abstract available.

PMID:
13263944

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