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Items: 7


Murine HSCs contribute actively to native hematopoiesis but with reduced differentiation capacity upon aging.

Säwen P, Eldeeb M, Erlandsson E, Kristiansen TA, Laterza C, Kokaia Z, Karlsson G, Yuan J, Soneji S, Mandal PK, Rossi DJ, Bryder D.

Elife. 2018 Dec 18;7. pii: e41258. doi: 10.7554/eLife.41258.


Critical Modulation of Hematopoietic Lineage Fate by Hepatic Leukemia Factor.

Wahlestedt M, Ladopoulos V, Hidalgo I, Sanchez Castillo M, Hannah R, Säwén P, Wan H, Dudenhöffer-Pfeifer M, Magnusson M, Norddahl GL, Göttgens B, Bryder D.

Cell Rep. 2017 Nov 21;21(8):2251-2263. doi: 10.1016/j.celrep.2017.10.112.


MLL-ENL-mediated leukemia initiation at the interface of lymphoid commitment.

Ugale A, Säwén P, Dudenhöffer-Pfeifer M, Wahlestedt M, Norddahl GL, Bryder D.

Oncogene. 2017 Jun 1;36(22):3207-3212. doi: 10.1038/onc.2016.470. Epub 2017 Jan 9.


Potential Pitfalls of the Mx1-Cre System: Implications for Experimental Modeling of Normal and Malignant Hematopoiesis.

Velasco-Hernandez T, Säwén P, Bryder D, Cammenga J.

Stem Cell Reports. 2016 Jul 12;7(1):11-8. doi: 10.1016/j.stemcr.2016.06.002. Epub 2016 Jun 30.


Mitotic History Reveals Distinct Stem Cell Populations and Their Contributions to Hematopoiesis.

Säwén P, Lang S, Mandal P, Rossi DJ, Soneji S, Bryder D.

Cell Rep. 2016 Mar 29;14(12):2809-18. doi: 10.1016/j.celrep.2016.02.073. Epub 2016 Mar 17.


Hematopoietic stem cells are intrinsically protected against MLL-ENL-mediated transformation.

Ugale A, Norddahl GL, Wahlestedt M, Säwén P, Jaako P, Pronk CJ, Soneji S, Cammenga J, Bryder D.

Cell Rep. 2014 Nov 20;9(4):1246-55. doi: 10.1016/j.celrep.2014.10.036. Epub 2014 Nov 13.


Bone marrow-derived hematopoietic cells generate cardiomyocytes at a low frequency through cell fusion, but not transdifferentiation.

Nygren JM, Jovinge S, Breitbach M, Säwén P, Röll W, Hescheler J, Taneera J, Fleischmann BK, Jacobsen SE.

Nat Med. 2004 May;10(5):494-501. Epub 2004 Apr 25.


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