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Items: 5


Spontaneous dormancy protects Trypanosoma cruzi during extended drug exposure.

Sánchez-Valdéz FJ, Padilla A, Wang W, Orr D, Tarleton RL.

Elife. 2018 Mar 26;7. pii: e34039. doi: 10.7554/eLife.34039.


Gene-deleted live-attenuated Trypanosoma cruzi parasites as vaccines to protect against Chagas disease.

Sánchez-Valdéz FJ, Pérez Brandán C, Ferreira A, Basombrío MÁ.

Expert Rev Vaccines. 2015 May;14(5):681-97. doi: 10.1586/14760584.2015.989989. Epub 2014 Dec 11. Review.


A monoallelic deletion of the TcCRT gene increases the attenuation of a cultured Trypanosoma cruzi strain, protecting against an in vivo virulent challenge.

Sánchez-Valdéz FJ, Pérez Brandán C, Ramírez G, Uncos AD, Zago MP, Cimino RO, Cardozo RM, Marco JD, Ferreira A, Basombrío MÁ.

PLoS Negl Trop Dis. 2014 Feb 13;8(2):e2696. doi: 10.1371/journal.pntd.0002696. eCollection 2014 Feb.


Trypanosoma cruzi carrying a monoallelic deletion of the calreticulin (TcCRT) gene are susceptible to complement mediated killing and defective in their metacyclogenesis.

Sánchez Valdéz FJ, Pérez Brandán C, Zago MP, Labriola C, Ferreira A, Basombrío MÁ.

Mol Immunol. 2013 Mar;53(3):198-205. doi: 10.1016/j.molimm.2012.08.001. Epub 2012 Sep 3.


Serological evaluation of specific-antibody levels in patients treated for chronic Chagas' disease.

Sánchez Negrette O, Sánchez Valdéz FJ, Lacunza CD, García Bustos MF, Mora MC, Uncos AD, Basombrío MA.

Clin Vaccine Immunol. 2008 Feb;15(2):297-302. Epub 2007 Dec 5.

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