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Best matches for Sá-Leão R[au]:

Puzzling Over the Pneumococcal Pangenome. Hiller NL et al. Front Microbiol. (2018)

Genomic Characterization of the Emerging Pathogen Streptococcus pseudopneumoniae. Garriss G et al. mBio. (2019)

Overview of molecular typing methods for outbreak detection and epidemiological surveillance. Sabat AJ et al. Euro Surveill. (2013)

Search results

Items: 1 to 50 of 60

1.

Genomic Characterization of the Emerging Pathogen Streptococcus pseudopneumoniae.

Garriss G, Nannapaneni P, Simões AS, Browall S, Subramanian K, Sá-Leão R, Goossens H, de Lencastre H, Henriques-Normark B.

mBio. 2019 Jun 25;10(3). pii: e01286-19. doi: 10.1128/mBio.01286-19.

2.

Identification of Streptococcus pneumoniae by a real-time PCR assay targeting SP2020.

Tavares DA, Handem S, Carvalho RJ, Paulo AC, de Lencastre H, Hinds J, Sá-Leão R.

Sci Rep. 2019 Mar 1;9(1):3285. doi: 10.1038/s41598-019-39791-1.

3.

Puzzling Over the Pneumococcal Pangenome.

Hiller NL, Sá-Leão R.

Front Microbiol. 2018 Oct 30;9:2580. doi: 10.3389/fmicb.2018.02580. eCollection 2018. Review.

4.

Periodic cycles of pneumococcal serotypes carried by children before and after 7-valent pneumococcal conjugate vaccine.

Paulo AC, Sá-Leão R.

PLoS One. 2017 Apr 28;12(4):e0176723. doi: 10.1371/journal.pone.0176723. eCollection 2017.

5.

Impact of the 13-valent pneumococcal conjugate vaccine on Streptococcus pneumoniae multiple serotype carriage.

Valente C, Hinds J, Gould KA, Pinto FR, de Lencastre H, Sá-Leão R.

Vaccine. 2016 Jul 25;34(34):4072-8. doi: 10.1016/j.vaccine.2016.06.017. Epub 2016 Jun 17.

PMID:
27325351
6.

The blp Locus of Streptococcus pneumoniae Plays a Limited Role in the Selection of Strains That Can Cocolonize the Human Nasopharynx.

Valente C, Dawid S, Pinto FR, Hinds J, Simões AS, Gould KA, Mendes LA, de Lencastre H, Sá-Leão R.

Appl Environ Microbiol. 2016 Aug 15;82(17):5206-15. doi: 10.1128/AEM.01048-16. Print 2016 Sep 1.

7.

lytA-based identification methods can misidentify Streptococcus pneumoniae.

Simões AS, Tavares DA, Rolo D, Ardanuy C, Goossens H, Henriques-Normark B, Linares J, de Lencastre H, Sá-Leão R.

Diagn Microbiol Infect Dis. 2016 Jun;85(2):141-8. doi: 10.1016/j.diagmicrobio.2016.03.018. Epub 2016 Mar 29.

PMID:
27107535
8.

Serotypes and Clonal Diversity of Streptococcus pneumoniae Causing Invasive Disease in the Era of PCV13 in Catalonia, Spain.

Del Amo E, Esteva C, Hernandez-Bou S, Galles C, Navarro M, Sauca G, Diaz A, Gassiot P, Marti C, Larrosa N, Ciruela P, Jane M, Sá-Leão R, Muñoz-Almagro C; Catalan Study Group of Invasive Pneumococcal Disease.

PLoS One. 2016 Mar 8;11(3):e0151125. doi: 10.1371/journal.pone.0151125. eCollection 2016.

9.

The impact of private use of PCV7 in 2009 and 2010 on serotypes and antimicrobial resistance of Streptococcus pneumoniae carried by young children in Portugal: Comparison with data obtained since 1996 generating a 15-year study prior to PCV13 introduction.

Nunes S, Félix S, Valente C, Simões AS, Tavares DA, Almeida ST, Paulo AC, Brito-Avô A, de Lencastre H, Sá-Leão R.

Vaccine. 2016 Mar 29;34(14):1648-56. doi: 10.1016/j.vaccine.2016.02.045. Epub 2016 Feb 23.

PMID:
26920470
10.

How direct competition shapes coexistence and vaccine effects in multi-strain pathogen systems.

Gjini E, Valente C, Sá-Leão R, Gomes MG.

J Theor Biol. 2016 Jan 7;388:50-60. doi: 10.1016/j.jtbi.2015.09.031. Epub 2015 Oct 22.

PMID:
26471070
11.

Serotype Distribution, Antibiotic Resistance and Clonality of Streptococcus pneumoniae Isolated from Immunocompromised Patients in Tunisia.

Raddaoui A, Simões AS, Baaboura R, Félix S, Achour W, Ben Othman T, Béjaoui M, Sá-Leão R, Ben Hassen A.

PLoS One. 2015 Oct 13;10(10):e0140390. doi: 10.1371/journal.pone.0140390. eCollection 2015.

12.

Ability of Antibiotic-Resistant Nonvaccine-Type Pneumococcal Clones to Cause Otitis Media in an Infant Mouse Model of Pneumococcal-Influenza Virus Coinfection.

Frazão N, Hermans P, van Selm S, Sá-Leão R, de Lencastre H, Tomasz A, Diavatopoulos D.

Microb Drug Resist. 2016 Jan;22(1):97-101. doi: 10.1089/mdr.2015.0109. Epub 2015 Sep 14.

PMID:
26366835
13.

Global phylogenomic analysis of nonencapsulated Streptococcus pneumoniae reveals a deep-branching classic lineage that is distinct from multiple sporadic lineages.

Hilty M, Wüthrich D, Salter SJ, Engel H, Campbell S, Sá-Leão R, de Lencastre H, Hermans P, Sadowy E, Turner P, Chewapreecha C, Diggle M, Pluschke G, McGee L, Eser ÖK, Low DE, Smith-Vaughan H, Endimiani A, Küffer M, Dupasquier M, Beaudoing E, Weber J, Bruggmann R, Hanage WP, Parkhill J, Hathaway LJ, Mühlemann K, Bentley SD.

Genome Biol Evol. 2014 Dec 4;6(12):3281-94. doi: 10.1093/gbe/evu263.

14.

Prevalence, risk factors, and epidemiology of methicillin-resistant Staphylococcus aureus carried by adults over 60 years of age.

Almeida ST, Nunes S, Paulo AC, Faria NA, de Lencastre H, Sá-Leão R.

Eur J Clin Microbiol Infect Dis. 2015 Mar;34(3):593-600. doi: 10.1007/s10096-014-2267-8. Epub 2014 Oct 31.

PMID:
25359581
15.

Non-typeable pneumococci circulating in Portugal are of cps type NCC2 and have genomic features typical of encapsulated isolates.

Tavares DA, Simões AS, Bootsma HJ, Hermans PW, de Lencastre H, Sá-Leão R.

BMC Genomics. 2014 Oct 6;15:863. doi: 10.1186/1471-2164-15-863.

16.

Variable recombination dynamics during the emergence, transmission and 'disarming' of a multidrug-resistant pneumococcal clone.

Croucher NJ, Hanage WP, Harris SR, McGee L, van der Linden M, de Lencastre H, Sá-Leão R, Song JH, Ko KS, Beall B, Klugman KP, Parkhill J, Tomasz A, Kristinsson KG, Bentley SD.

BMC Biol. 2014 Jun 23;12:49. doi: 10.1186/1741-7007-12-49.

17.

Evidence for soft selective sweeps in the evolution of pneumococcal multidrug resistance and vaccine escape.

Croucher NJ, Chewapreecha C, Hanage WP, Harris SR, McGee L, van der Linden M, Song JH, Ko KS, de Lencastre H, Turner C, Yang F, Sá-Leão R, Beall B, Klugman KP, Parkhill J, Turner P, Bentley SD.

Genome Biol Evol. 2014 Jun 10;6(7):1589-602. doi: 10.1093/gbe/evu120.

18.

Low prevalence of pneumococcal carriage and high serotype and genotype diversity among adults over 60 years of age living in Portugal.

Almeida ST, Nunes S, Santos Paulo AC, Valadares I, Martins S, Breia F, Brito-Avô A, Morais A, de Lencastre H, Sá-Leão R.

PLoS One. 2014 Mar 6;9(3):e90974. doi: 10.1371/journal.pone.0090974. eCollection 2014.

19.

High invasiveness of pneumococcal serotypes included in the new generation of conjugate vaccines.

del Amo E, Brotons P, Monsonis M, Triviño M, Iñigo M, Selva L, Sa-Leão R, Muñoz-Almagro C.

Clin Microbiol Infect. 2014 Jul;20(7):684-9. doi: 10.1111/1469-0691.12422. Epub 2013 Nov 8.

20.

Standard method for detecting upper respiratory carriage of Streptococcus pneumoniae: updated recommendations from the World Health Organization Pneumococcal Carriage Working Group.

Satzke C, Turner P, Virolainen-Julkunen A, Adrian PV, Antonio M, Hare KM, Henao-Restrepo AM, Leach AJ, Klugman KP, Porter BD, Sá-Leão R, Scott JA, Nohynek H, O'Brien KL; WHO Pneumococcal Carriage Working Group.

Vaccine. 2013 Dec 17;32(1):165-79. doi: 10.1016/j.vaccine.2013.08.062. Review.

21.

Characteristics of Haemophilus influenzae invasive isolates from Portugal following routine childhood vaccination against H. influenzae serotype b (2002-2010).

Bajanca-Lavado MP, Simões AS, Betencourt CR, Sá-Leão R; Portuguese Group for Study of Haemophilus influenzae invasive infection.

Eur J Clin Microbiol Infect Dis. 2014 Apr;33(4):603-10. doi: 10.1007/s10096-013-1994-6. Epub 2013 Oct 24.

PMID:
24154654
22.

Virulence potential and genome-wide characterization of drug resistant Streptococcus pneumoniae clones selected in vivo by the 7-valent pneumococcal conjugate vaccine.

Frazão N, Hiller NL, Powell E, Earl J, Ahmed A, Sá-Leão R, de Lencastre H, Ehrlich GD, Tomasz A.

PLoS One. 2013 Sep 19;8(9):e74867. doi: 10.1371/journal.pone.0074867. eCollection 2013.

23.
24.

Selection of distinctive colony morphologies for detection of multiple carriage of Streptococcus pneumoniae.

Valente C, de Lencastre H, Sá-Leão R.

Pediatr Infect Dis J. 2013 Jun;32(6):703-4. doi: 10.1097/INF.0b013e31828692be. No abstract available.

PMID:
23838735
25.

Comparative analysis of Streptococcus pneumoniae transmission in Portuguese and Finnish day-care centres.

Pessoa D, Hoti F, Syrjänen R, Sá-Leão R, Kaijalainen T, Gomes MG, Auranen K.

BMC Infect Dis. 2013 Apr 18;13:180. doi: 10.1186/1471-2334-13-180.

26.

Disease isolates of Streptococcus pseudopneumoniae and non-typeable S. pneumoniae presumptively identified as atypical S. pneumoniae in Spain.

Rolo D, S Simões A, Domenech A, Fenoll A, Liñares J, de Lencastre H, Ardanuy C, Sá-Leão R.

PLoS One. 2013;8(2):e57047. doi: 10.1371/journal.pone.0057047. Epub 2013 Feb 21.

27.

Overview of molecular typing methods for outbreak detection and epidemiological surveillance.

Sabat AJ, Budimir A, Nashev D, Sá-Leão R, van Dijl Jm, Laurent F, Grundmann H, Friedrich AW; ESCMID Study Group of Epidemiological Markers (ESGEM).

Euro Surveill. 2013 Jan 24;18(4):20380. Review.

28.

Pherotypes of co-colonizing pneumococci among Portuguese children.

Valente C, De Lencastre H, Sá-Leão R.

Microb Drug Resist. 2012 Dec;18(6):550-4. doi: 10.1089/mdr.2011.0228. Epub 2012 Jul 12.

PMID:
22788981
29.

Decrease in pneumococcal co-colonization following vaccination with the seven-valent pneumococcal conjugate vaccine.

Valente C, Hinds J, Pinto F, Brugger SD, Gould K, Mühlemann K, de Lencastre H, Sá-Leão R.

PLoS One. 2012;7(1):e30235. doi: 10.1371/journal.pone.0030235. Epub 2012 Jan 12.

30.

Differences in genotype and virulence among four multidrug-resistant Streptococcus pneumoniae isolates belonging to the PMEN1 clone.

Hiller NL, Eutsey RA, Powell E, Earl JP, Janto B, Martin DP, Dawid S, Ahmed A, Longwell MJ, Dahlgren ME, Ezzo S, Tettelin H, Daugherty SC, Mitchell TJ, Hillman TA, Buchinsky FJ, Tomasz A, de Lencastre H, Sá-Leão R, Post JC, Hu FZ, Ehrlich GD.

PLoS One. 2011;6(12):e28850. doi: 10.1371/journal.pone.0028850. Epub 2011 Dec 19.

31.

Rapid identification of noncapsulated Streptococcus pneumoniae in nasopharyngeal samples allowing detection of co-colonization and reevaluation of prevalence.

Simões AS, Valente C, de Lencastre H, Sá-Leão R.

Diagn Microbiol Infect Dis. 2011 Nov;71(3):208-16. doi: 10.1016/j.diagmicrobio.2011.07.009. Epub 2011 Sep 9.

PMID:
21907526
32.

Multiple-locus variable number tandem repeat analysis for Streptococcus pneumoniae: comparison with PFGE and MLST.

Elberse KE, Nunes S, Sá-Leão R, van der Heide HG, Schouls LM.

PLoS One. 2011;6(5):e19668. doi: 10.1371/journal.pone.0019668. Epub 2011 May 26.

33.

Clonal evolution leading to maintenance of antibiotic resistance rates among colonizing Pneumococci in the PCV7 era in Portugal.

Simões AS, Pereira L, Nunes S, Brito-Avô A, de Lencastre H, Sá-Leão R.

J Clin Microbiol. 2011 Aug;49(8):2810-7. doi: 10.1128/JCM.00517-11. Epub 2011 Jun 1.

34.

Analysis of invasiveness of pneumococcal serotypes and clones circulating in Portugal before widespread use of conjugate vaccines reveals heterogeneous behavior of clones expressing the same serotype.

Sá-Leão R, Pinto F, Aguiar S, Nunes S, Carriço JA, Frazão N, Gonçalves-Sousa N, Melo-Cristino J, de Lencastre H, Ramirez M.

J Clin Microbiol. 2011 Apr;49(4):1369-75. doi: 10.1128/JCM.01763-10. Epub 2011 Jan 26.

35.

Large screening of CA-MRSA among Staphylococcus aureus colonizing healthy young children living in two areas (urban and rural) of Portugal.

Tavares DA, Sá-Leão R, Miragaia M, de Lencastre H.

BMC Infect Dis. 2010 May 3;10:110. doi: 10.1186/1471-2334-10-110.

36.

Impact of a single dose of the 7-valent pneumococcal conjugate vaccine on colonization.

Frazão N, Sá-Leão R, de Lencastre H.

Vaccine. 2010 Apr 26;28(19):3445-52. doi: 10.1016/j.vaccine.2010.02.070. Epub 2010 Mar 1.

PMID:
20197144
37.

Highly penicillin-resistant multidrug-resistant pneumococcus-like strains colonizing children in Oeiras, Portugal: genomic characteristics and implications for surveillance.

Simões AS, Sá-Leão R, Eleveld MJ, Tavares DA, Carriço JA, Bootsma HJ, Hermans PW.

J Clin Microbiol. 2010 Jan;48(1):238-46. doi: 10.1128/JCM.01313-09. Epub 2009 Nov 11.

38.

Denmark14-230 clone as an increasing cause of pneumococcal infection in Portugal within a background of diverse serotype 19A lineages.

Aguiar SI, Pinto FR, Nunes S, Serrano I, Melo-Cristino J, Sá-Leão R, Ramirez M, de Lencastre H.

J Clin Microbiol. 2010 Jan;48(1):101-8. doi: 10.1128/JCM.00665-09. Epub 2009 Oct 28.

39.

Streptococcus pneumoniae nasopharyngeal carriage in children attending day-care centers in the central region of Portugal, in the era of 7-valent pneumococcal conjugate vaccine.

Rodrigues F, Nunes S, Sá-Leão R, Gonçalves G, Lemos L, de Lencastre H.

Microb Drug Resist. 2009 Dec;15(4):269-77. doi: 10.1089/mdr.2009.0043.

PMID:
19857133
40.

Changes in pneumococcal serotypes and antibiotypes carried by vaccinated and unvaccinated day-care centre attendees in Portugal, a country with widespread use of the seven-valent pneumococcal conjugate vaccine.

Sá-Leão R, Nunes S, Brito-Avô A, Frazão N, Simões AS, Crisóstomo MI, Paulo AC, Saldanha J, Santos-Sanches I, de Lencastre H.

Clin Microbiol Infect. 2009 Nov;15(11):1002-7. doi: 10.1111/j.1469-0691.2009.02775.x. Epub 2009 Apr 23.

41.

Temporal trends and molecular epidemiology of recently described serotype 6C of Streptococcus pneumoniae.

Nunes S, Valente C, Sá-Leão R, de Lencastre H.

J Clin Microbiol. 2009 Feb;47(2):472-4. doi: 10.1128/JCM.01984-08. Epub 2008 Dec 10.

42.

Optochin resistance among Streptococcus pneumoniae strains colonizing healthy children in Portugal.

Nunes S, Sá-Leão R, de Lencastre H.

J Clin Microbiol. 2008 Jan;46(1):321-4. Epub 2007 Nov 21.

43.

High rates of transmission of and colonization by Streptococcus pneumoniae and Haemophilus influenzae within a day care center revealed in a longitudinal study.

Sá-Leão R, Nunes S, Brito-Avô A, Alves CR, Carriço JA, Saldanha J, Almeida JS, Santos-Sanches I, de Lencastre H.

J Clin Microbiol. 2008 Jan;46(1):225-34. Epub 2007 Nov 14.

44.

Emergence of a serotype 1 Streptococcus pneumoniae lineage colonising healthy children in Portugal in the seven-valent conjugate vaccination era.

Nunes S, Sá-Leão R, Pereira LC, de Lencastre H.

Clin Microbiol Infect. 2008 Jan;14(1):82-4. Epub 2007 Nov 6.

45.

Identification, prevalence and population structure of non-typable Streptococcus pneumoniae in carriage samples isolated from preschoolers attending day-care centres.

Sá-Leão R, Simões AS, Nunes S, Sousa NG, Frazão N, de Lencastre H.

Microbiology. 2006 Feb;152(Pt 2):367-76.

PMID:
16436425
46.

Properties of novel international drug-resistant pneumococcal clones identified in day-care centers of Lisbon, Portugal.

Sousa NG, Sá-Leão R, Crisóstomo MI, Simas C, Nunes S, Frazão N, Carriço JA, Mato R, Santos-Sanches I, de Lencastre H.

J Clin Microbiol. 2005 Sep;43(9):4696-703.

47.

Trends in drug resistance, serotypes, and molecular types of Streptococcus pneumoniae colonizing preschool-age children attending day care centers in Lisbon, Portugal: a summary of 4 years of annual surveillance.

Nunes S, Sá-Leão R, Carriço J, Alves CR, Mato R, Avô AB, Saldanha J, Almeida JS, Sanches IS, de Lencastre H.

J Clin Microbiol. 2005 Mar;43(3):1285-93.

48.

Clonal and antibiotic resistance profiles of methicillin-resistant Staphylococcus aureus (MRSA) from a Portuguese hospital over time.

Amorim ML, Aires de Sousa M, Sanches IS, Sá-Leão R, Cabeda JM, Amorim JM, de Lencastre H.

Microb Drug Resist. 2002 Winter;8(4):301-9.

PMID:
12523627
49.

Pilot study of the genetic diversity of the pneumococcal nasopharyngeal flora among children attending day care centers.

Sá-Leão R, Tomasz A, Santos Sanches I, de Lencastre H.

J Clin Microbiol. 2002 Oct;40(10):3577-85.

50.

Diversity of penicillin-nonsusceptible Streptococcus pneumoniae circulating in Iceland after the introduction of penicillin-resistant clone Spain(6B)-2.

Sá-Leão R, Vilhelmsson SE, de Lencastre H, Kristinsson KG, Tomasz A.

J Infect Dis. 2002 Oct 1;186(7):966-75. Epub 2002 Sep 9.

PMID:
12232837

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