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Items: 9


The acquisition of mechano-electrical transducer current adaptation in auditory hair cells requires myosin VI.

Marcotti W, Corns LF, Goodyear RJ, Rzadzinska AK, Avraham KB, Steel KP, Richardson GP, Kros CJ.

J Physiol. 2016 Jul 1;594(13):3667-81. doi: 10.1113/JP272220. Epub 2016 May 27.


The circling mutant Pcdh15roda is a new mouse model for hearing loss.

Torres AA, Rzadzinska AK, Ribeiro AF, Silva DA, Guénet JL, Massironi SM, Godard AL.

Mutat Res. 2013 Nov-Dec;751-752:29-35. doi: 10.1016/j.mrfmmm.2013.09.002. Epub 2013 Sep 14.


Multi-isotope imaging mass spectrometry reveals slow protein turnover in hair-cell stereocilia.

Zhang DS, Piazza V, Perrin BJ, Rzadzinska AK, Poczatek JC, Wang M, Prosser HM, Ervasti JM, Corey DP, Lechene CP.

Nature. 2012 Jan 15;481(7382):520-4. doi: 10.1038/nature10745.


MyosinVIIa interacts with Twinfilin-2 at the tips of mechanosensory stereocilia in the inner ear.

Rzadzinska AK, Nevalainen EM, Prosser HM, Lappalainen P, Steel KP.

PLoS One. 2009 Sep 23;4(9):e7097. doi: 10.1371/journal.pone.0007097.


Presence of interstereocilial links in waltzer mutants suggests Cdh23 is not essential for tip link formation.

Rzadzinska AK, Steel KP.

Neuroscience. 2009 Jan 23;158(2):365-8. doi: 10.1016/j.neuroscience.2008.10.012. Epub 2008 Oct 17.


A Myo6 mutation destroys coordination between the myosin heads, revealing new functions of myosin VI in the stereocilia of mammalian inner ear hair cells.

Hertzano R, Shalit E, Rzadzinska AK, Dror AA, Song L, Ron U, Tan JT, Shitrit AS, Fuchs H, Hasson T, Ben-Tal N, Sweeney HL, de Angelis MH, Steel KP, Avraham KB.

PLoS Genet. 2008 Oct 3;4(10):e1000207. doi: 10.1371/journal.pgen.1000207.


Mosaic complementation demonstrates a regulatory role for myosin VIIa in actin dynamics of stereocilia.

Prosser HM, Rzadzinska AK, Steel KP, Bradley A.

Mol Cell Biol. 2008 Mar;28(5):1702-12. Epub 2007 Dec 26.


Sustained cadherin 23 expression in young and adult cochlea of normal and hearing-impaired mice.

Rzadzinska AK, Derr A, Kachar B, Noben-Trauth K.

Hear Res. 2005 Oct;208(1-2):114-21. Epub 2005 Jul 6.


An actin molecular treadmill and myosins maintain stereocilia functional architecture and self-renewal.

Rzadzinska AK, Schneider ME, Davies C, Riordan GP, Kachar B.

J Cell Biol. 2004 Mar 15;164(6):887-97.

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