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Improvement of spinal muscular atrophy via correction of the SMN2 splicing defect by Brucea javanica (L.) Merr. extract and Bruceine D.

Baek J, Jeong H, Ham Y, Jo YH, Choi M, Kang M, Son B, Choi S, Ryu HW, Kim J, Shen H, Sydara K, Lee SW, Kim SY, Han SB, Oh SR, Cho S.

Phytomedicine. 2019 Sep 16;65:153089. doi: 10.1016/j.phymed.2019.153089. [Epub ahead of print]


Simultaneous mitigation of methane and odors in a biowindow using a pipe network.

Jung H, Oh KC, Ryu HW, Jeon JM, Cho KS.

Waste Manag. 2019 Sep 11;100:45-56. doi: 10.1016/j.wasman.2019.09.004. [Epub ahead of print]


Anti-inflammatory flavonoids from root bark of Broussonetia papyrifera in LPS-stimulated RAW264.7 cells.

Ryu HW, Park MH, Kwon OK, Kim DY, Hwang JY, Jo YH, Ahn KS, Hwang BY, Oh SR.

Bioorg Chem. 2019 Aug 29;92:103233. doi: 10.1016/j.bioorg.2019.103233. [Epub ahead of print]


Inhibitory effects of flavonoids isolated from Sophora flavescens on indoleamine 2,3-dioxygenase 1 activity.

Kwon M, Ko SK, Jang M, Kim GH, Ryoo IJ, Son S, Ryu HW, Oh SR, Lee WK, Kim BY, Jang JH, Ahn JS.

J Enzyme Inhib Med Chem. 2019 Dec;34(1):1481-1488. doi: 10.1080/14756366.2019.1640218.


Corrigendum to "Zanthoxylum ailanthoides Suppresses Oleic Acid-Induced Lipid Accumulation through an Activation of LKB1/AMPK Pathway in HepG2 Cells".

Kwon EB, Kang MJ, Kim SY, Lee YM, Lee MK, Yuk HJ, Ryu HW, Lee SU, Oh SR, Moon DO, Lee HS, Kim MO.

Evid Based Complement Alternat Med. 2019 Jul 14;2019:3498219. doi: 10.1155/2019/3498219. eCollection 2019.


Repurposing mosloflavone/5,6,7-trimethoxyflavone-resveratrol hybrids: Discovery of novel p38-α MAPK inhibitors as potent interceptors of macrophage-dependent production of proinflammatory mediators.

Hassan AHE, Yoo SY, Lee KW, Yoon YM, Ryu HW, Jeong Y, Shin JS, Kang SY, Kim SY, Lee HH, Park BY, Lee KT, Lee YS.

Eur J Med Chem. 2019 Oct 15;180:253-267. doi: 10.1016/j.ejmech.2019.07.030. Epub 2019 Jul 9.


HDAC6‑selective inhibitor synergistically enhances the anticancer activity of immunomodulatory drugs in multiple myeloma.

Won HR, Lee DH, Yeon SK, Ryu HW, Kim GW, Kwon SH.

Int J Oncol. 2019 Aug;55(2):499-512. doi: 10.3892/ijo.2019.4828. Epub 2019 Jun 20.


Pistacia weinmannifolia ameliorates cigarette smoke and lipopolysaccharide‑induced pulmonary inflammation by inhibiting interleukin‑8 production and NF‑κB activation.

Lee JW, Ryu HW, Lee SU, Kim MG, Kwon OK, Kim MO, Oh TK, Lee JK, Kim TY, Lee SW, Choi S, Li WY, Ahn KS, Oh SR.

Int J Mol Med. 2019 Sep;44(3):949-959. doi: 10.3892/ijmm.2019.4247. Epub 2019 Jun 20.


Calotropis gigantea extract induces apoptosis through extrinsic/intrinsic pathways and reactive oxygen species generation in A549 and NCI-H1299 non-small cell lung cancer cells.

Lee J, Jang HJ, Chun H, Pham TH, Bak Y, Shin JW, Jin H, Kim YI, Ryu HW, Oh SR, Yoon DY.

BMC Complement Altern Med. 2019 Jun 18;19(1):134. doi: 10.1186/s12906-019-2561-1.


Picroside II Isolated from Pseudolysimachion rotundum var. subintegrum Inhibits Glucocorticoid Refractory Serum Amyloid A (SAA) Expression and SAA-induced IL-33 Secretion.

Lee K, Choi J, Choi BK, Gu YM, Ryu HW, Oh SR, Lee HJ.

Molecules. 2019 May 27;24(10). pii: E2020. doi: 10.3390/molecules24102020.


Tuning the Hydrophobicity of a Hydrogel Using Self-Assembled Domains of Polymer Cross-Linkers.

Kim HJ, Cho S, Oh SJ, Shin SG, Ryu HW, Jeong JH.

Materials (Basel). 2019 May 19;12(10). pii: E1635. doi: 10.3390/ma12101635.


Epimagnolin A inhibits IL-6 production by inhibiting p38/NF-κB and AP-1 signaling pathways in PMA-stimulated THP-1 cells.

Chun HW, Kim SJ, Pham TH, Bak Y, Oh J, Ryu HW, Oh SR, Hong JT, Yoon DY.

Environ Toxicol. 2019 Jul;34(7):796-803. doi: 10.1002/tox.22746. Epub 2019 Mar 27.


The novel methoxetamine analogs N-ethylnorketamine hydrochloride (NENK), 2-MeO-N-ethylketamine hydrochloride (2-MeO-NEK), and 4-MeO-N-ethylketamine hydrochloride (4-MeO-NEK) elicit rapid antidepressant effects via activation of AMPA and 5-HT2 receptors.

Sayson LV, Botanas CJ, Custodio RJP, Abiero A, Kim M, Lee HJ, Kim HJ, Yoo SY, Lee KW, Ryu HW, Acharya S, Kim KM, Lee YS, Cheong JH.

Psychopharmacology (Berl). 2019 Jul;236(7):2201-2210. doi: 10.1007/s00213-019-05219-x. Epub 2019 Mar 19.


Biofunctional soyasaponin Bb in peanut (Arachis hypogaea L.) sprouts enhances bone morphogenetic protein-2-dependent osteogenic differentiation via activation of runt-related transcription factor 2 in C2C12 cells.

Kim SH, Yuk HJ, Ryu HW, Oh SR, Song DY, Lee KS, Park KI, Choi SW, Seo WD.

Phytother Res. 2019 May;33(5):1490-1500. doi: 10.1002/ptr.6341. Epub 2019 Mar 18.


Removal of toluene using ozone at room temperature over mesoporous Mn/Al2O3 catalysts.

Ryu HW, Song MY, Park JS, Kim JM, Jung SC, Song J, Kim BJ, Park YK.

Environ Res. 2019 May;172:649-657. doi: 10.1016/j.envres.2019.03.016. Epub 2019 Mar 7.


Physalis peruviana L. inhibits ovalbumin‑induced airway inflammation by attenuating the activation of NF‑κB and inflammatory molecules.

Park HA, Kwon OK, Ryu HW, Min JH, Park MW, Park MH, Paik JH, Choi S, Paryanto I, Yuniato P, Oh SR, Ahn KS, Lee JW.

Int J Mol Med. 2019 Apr;43(4):1830-1838. doi: 10.3892/ijmm.2019.4110. Epub 2019 Feb 26.


Osthenol, a prenylated coumarin, as a monoamine oxidase A inhibitor with high selectivity.

Baek SC, Kang MG, Park JE, Lee JP, Lee H, Ryu HW, Park CM, Park D, Cho ML, Oh SR, Kim H.

Bioorg Med Chem Lett. 2019 Mar 15;29(6):839-843. doi: 10.1016/j.bmcl.2019.01.016. Epub 2019 Jan 18.


Comparison of three heterochromatin protein 1 homologs in Drosophila.

Lee DH, Ryu HW, Kim GW, Kwon SH.

J Cell Sci. 2019 Feb 7;132(3). pii: jcs222729. doi: 10.1242/jcs.222729.


Comparison of flavonoid and policosanol profiles in Korean winter-spinach (Spinacia oleracea L.) cultivated in different regions.

Yuk HJ, Ryu HW, Kim DY, Park MH, Seo WD, Jeong SH, Oh SR.

Food Chem. 2019 May 1;279:202-208. doi: 10.1016/j.foodchem.2018.11.143. Epub 2018 Dec 6.


Orientin inhibits invasion by suppressing MMP-9 and IL-8 expression via the PKCα/ ERK/AP-1/STAT3-mediated signaling pathways in TPA-treated MCF-7 breast cancer cells.

Kim SJ, Pham TH, Bak Y, Ryu HW, Oh SR, Yoon DY.

Phytomedicine. 2018 Nov 15;50:35-42. doi: 10.1016/j.phymed.2018.09.172. Epub 2018 Sep 18.


Rhamnocitrin isolated from Prunus padus var. seoulensis: A potent and selective reversible inhibitor of human monoamine oxidase A.

Baek SC, Park MH, Ryu HW, Lee JP, Kang MG, Park D, Park CM, Oh SR, Kim H.

Bioorg Chem. 2019 Mar;83:317-325. doi: 10.1016/j.bioorg.2018.10.051. Epub 2018 Oct 28.


Performance evaluation of an on-site biocomplex textile as an alternative daily cover in a sanitary landfill, South Korea.

Yun J, Jung H, Choi H, Oh KC, Jeon JM, Ryu HW, Cho KS.

Waste Manag Res. 2018 Dec;36(12):1137-1145. doi: 10.1177/0734242X18806996. Epub 2018 Oct 31.


Lignans Isolated From Flower Buds of Magnolia fargesii Attenuate Airway Inflammation Induced by Cigarette Smoke in vitro and in vivo.

Lee SU, Ryu HW, Lee S, Shin IS, Choi JH, Lee JW, Lee J, Kim MO, Lee HJ, Ahn KS, Hong ST, Oh SR.

Front Pharmacol. 2018 Sep 7;9:970. doi: 10.3389/fphar.2018.00970. eCollection 2018.


3,4,5-Trihydroxycinnamic acid attenuates lipopolysaccharide (LPS)-induced acute lung injury via downregulating inflammatory molecules and upregulating HO-1/AMPK activation.

Lee JW, Chun W, Kwon OK, Park HA, Lim Y, Lee JH, Kim DY, Kim JH, Lee HK, Ryu HW, Oh SR, Ahn KS.

Int Immunopharmacol. 2018 Nov;64:123-130. doi: 10.1016/j.intimp.2018.08.015. Epub 2018 Aug 31.


Characterization of odor emissions and microbial community structure during degradation of pig carcasses using the soil burial-composting method.

Ki BM, Kim YM, Jeon JM, Ryu HW, Cho KS.

Waste Manag. 2018 Jul;77:30-42. doi: 10.1016/j.wasman.2018.04.043. Epub 2018 May 8.


Odor mitigation and bacterial community dynamics in on-site biocovers at a sanitary landfill in South Korea.

Yun J, Jung H, Ryu HW, Oh KC, Jeon JM, Cho KS.

Environ Res. 2018 Oct;166:516-528. doi: 10.1016/j.envres.2018.06.039. Epub 2018 Jun 27.


Selective inhibition of monoamine oxidase A by chelerythrine, an isoquinoline alkaloid.

Baek SC, Ryu HW, Kang MG, Lee H, Park D, Cho ML, Oh SR, Kim H.

Bioorg Med Chem Lett. 2018 Aug 1;28(14):2403-2407. doi: 10.1016/j.bmcl.2018.06.023. Epub 2018 Jun 18.


A452, an HDAC6-selective inhibitor, synergistically enhances the anticancer activity of chemotherapeutic agents in colorectal cancer cells.

Won HR, Ryu HW, Shin DH, Yeon SK, Lee DH, Kwon SH.

Mol Carcinog. 2018 Oct;57(10):1383-1395. doi: 10.1002/mc.22852. Epub 2018 Jun 22.


Low-Dose Evans Blue Dye for Near-Infrared Fluorescence Imaging in Photothrombotic Stroke Model.

Ryu HW, Lim W, Jo D, Kim S, Park JT, Min JJ, Hyun H, Kim HS.

Int J Med Sci. 2018 Apr 27;15(7):696-702. doi: 10.7150/ijms.24257. eCollection 2018.


Polyacetylene From Dendropanax morbifera Alleviates Diet-Induced Obesity and Hepatic Steatosis by Activating AMPK Signaling Pathway.

Kang MJ, Kwon EB, Ryu HW, Lee S, Lee JW, Kim DY, Lee MK, Oh SR, Lee HS, Lee SU, Kim MO.

Front Pharmacol. 2018 May 23;9:537. doi: 10.3389/fphar.2018.00537. eCollection 2018.


The HDAC6 inhibitor ACY‑1215 enhances the anticancer activity of oxaliplatin in colorectal cancer cells.

Lee DH, Won HR, Ryu HW, Han JM, Kwon SH.

Int J Oncol. 2018 Aug;53(2):844-854. doi: 10.3892/ijo.2018.4405. Epub 2018 May 11.


Anti-inflammatory effects of Passiflora foetida L. in LPS-stimulated RAW264.7 macrophages.

Park JW, Kwon OK, Ryu HW, Paik JH, Paryanto I, Yuniato P, Choi S, Oh SR, Ahn KS.

Int J Mol Med. 2018 Jun;41(6):3709-3716. doi: 10.3892/ijmm.2018.3559. Epub 2018 Mar 12.


Zanthoxylum ailanthoides Suppresses Oleic Acid-Induced Lipid Accumulation through an Activation of LKB1/AMPK Pathway in HepG2 Cells.

Kwon EB, Kang MJ, Kim SY, Lee YM, Lee MK, Yuk HJ, Ryu HW, Lee SU, Oh SR, Moon DO, Lee HS, Kim MO.

Evid Based Complement Alternat Med. 2018 Jan 8;2018:3140267. doi: 10.1155/2018/3140267. eCollection 2018. Erratum in: Evid Based Complement Alternat Med. 2019 Jul 14;2019:3498219.


Piscroside C inhibits TNF-α/NF-κB pathway by the suppression of PKCδ activity for TNF-RSC formation in human airway epithelial cells.

Lee SU, Lee S, Ro H, Choi JH, Ryu HW, Kim MO, Yuk HJ, Lee J, Hong ST, Oh SR.

Phytomedicine. 2018 Feb 1;40:148-157. doi: 10.1016/j.phymed.2018.01.012. Epub 2018 Jan 31.


Extended local similarity analysis (eLSA) reveals unique associations between bacterial community structure and odor emission during pig carcasses decomposition.

Ki BM, Ryu HW, Cho KS.

J Environ Sci Health A Tox Hazard Subst Environ Eng. 2018 Jul 3;53(8):718-727. doi: 10.1080/10934529.2018.1439856. Epub 2018 Feb 22.


Selective inhibition of monoamine oxidase A by hispidol.

Baek SC, Lee HW, Ryu HW, Kang MG, Park D, Kim SH, Cho ML, Oh SR, Kim H.

Bioorg Med Chem Lett. 2018 Feb 15;28(4):584-588. doi: 10.1016/j.bmcl.2018.01.049. Epub 2018 Jan 31.


ZW800-1 for Assessment of Blood-Brain Barrier Disruption in a Photothrombotic Stroke Model.

Lee S, Lim W, Ryu HW, Jo D, Min JJ, Kim HS, Hyun H.

Int J Med Sci. 2017 Nov 2;14(13):1430-1435. doi: 10.7150/ijms.22294. eCollection 2017.


Biocomplex textile as an alternative daily cover for the simultaneous mitigation of methane and malodorous compounds.

Choi H, Ryu HW, Cho KS.

Waste Manag. 2018 Feb;72:339-348. doi: 10.1016/j.wasman.2017.11.017. Epub 2017 Nov 10.


Tripterygium regelii decreases the biosynthesis of triacylglycerol and cholesterol in HepG2 cells.

Kang MJ, Kwon EB, Yuk HJ, Ryu HW, Kim SY, Lee MK, Moon DO, Lee SU, Oh SR, Lee HS, Kim MO.

Biosci Biotechnol Biochem. 2017 Dec;81(12):2285-2291. doi: 10.1080/09168451.2017.1390392. Epub 2017 Nov 1.


Seasonal characteristics of odor and methane mitigation and the bacterial community dynamics in an on-site biocover at a sanitary landfill.

Lee YY, Jung H, Ryu HW, Oh KC, Jeon JM, Cho KS.

Waste Manag. 2018 Jan;71:277-286. doi: 10.1016/j.wasman.2017.10.037. Epub 2017 Oct 28.


Artemisia argyi attenuates airway inflammation in lipopolysaccharide induced acute lung injury model.

Shin NR, Park SH, Ko JW, Ryu HW, Jeong SH, Kim JC, Shin DH, Lee HS, Shin IS.

Lab Anim Res. 2017 Sep;33(3):209-215. doi: 10.5625/lar.2017.33.3.209. Epub 2017 Sep 27.


Protective effects of neem (Azadirachta indica A. Juss.) leaf extract against cigarette smoke- and lipopolysaccharide-induced pulmonary inflammation.

Lee JW, Ryu HW, Park SY, Park HA, Kwon OK, Yuk HJ, Shrestha KK, Park M, Kim JH, Lee S, Oh SR, Ahn KS.

Int J Mol Med. 2017 Dec;40(6):1932-1940. doi: 10.3892/ijmm.2017.3178. Epub 2017 Oct 10.


Characterization of Bacterial Community Dynamics during the Decomposition of Pig Carcasses in Simulated Soil Burial and Composting Systems.

Ki BM, Kim YM, Jeon JM, Ryu HW, Cho KS.

J Microbiol Biotechnol. 2017 Dec 28;27(12):2199-2210. doi: 10.4014/jmb.1709.09032.


Potential Anti-inflammatory Effects of the Fruits of Paulownia tomentosa.

Ryu HW, Park YJ, Lee SU, Lee S, Yuk HJ, Seo KH, Kim YU, Hwang BY, Oh SR.

J Nat Prod. 2017 Oct 27;80(10):2659-2665. doi: 10.1021/acs.jnatprod.7b00325. Epub 2017 Oct 2.


Physalis peruviana L. inhibits airway inflammation induced by cigarette smoke and lipopolysaccharide through inhibition of extracellular signal-regulated kinase and induction of heme oxygenase-1.

Park HA, Lee JW, Kwon OK, Lee G, Lim Y, Kim JH, Paik JH, Choi S, Paryanto I, Yuniato P, Kim DY, Ryu HW, Oh SR, Lee SJ, Ahn KS.

Int J Mol Med. 2017 Nov;40(5):1557-1565. doi: 10.3892/ijmm.2017.3139. Epub 2017 Sep 15.


Cytotoxic activities of Telectadium dongnaiense and its constituents by inhibition of the Wnt/β-catenin signaling pathway.

Kim WK, Bach DH, Ryu HW, Oh J, Park HJ, Hong JY, Song HH, Eum S, Bach TT, Lee SK.

Phytomedicine. 2017 Oct 15;34:136-142. doi: 10.1016/j.phymed.2017.08.008. Epub 2017 Aug 12.


Anti-inflammatory effect of stem bark of Paulownia tomentosa Steud. in lipopolysaccharide (LPS)-stimulated RAW264.7 macrophages and LPS-induced murine model of acute lung injury.

Lee JW, Seo KH, Ryu HW, Yuk HJ, Park HA, Lim Y, Ahn KS, Oh SR.

J Ethnopharmacol. 2018 Jan 10;210:23-30. doi: 10.1016/j.jep.2017.08.028. Epub 2017 Aug 24.


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