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Items: 1 to 50 of 90

1.

Dry powder inhalation exposures of the endotracheally intubated rat lung, ex vivo and in vivo: the pulmonary pharmacokinetics of fluticasone furoate.

Selg E, Ewing P, Acevedo F, Sjöberg CO, Ryrfeldt A, Gerde P.

J Aerosol Med Pulm Drug Deliv. 2013 Aug;26(4):181-9. doi: 10.1089/jamp.2012.0971. Epub 2012 Oct 24.

PMID:
23094685
2.

Comparison of aerosol and intranasal challenge in a mouse model of allergic airway inflammation and hyperresponsiveness.

Swedin L, Ellis R, Kemi C, Ryrfeldt A, Inman M, Dahlén SE, Adner M.

Int Arch Allergy Immunol. 2010;153(3):249-58. doi: 10.1159/000314365. Epub 2010 May 19.

PMID:
20484923
3.

Delivering horseradish peroxidase as a respirable powder to the isolated, perfused, and ventilated lung of the rat: the pulmonary disposition of an inhaled model biopharmaceutical.

Selg E, Acevedo F, Nybom R, Blomgren B, Ryrfeldt A, Gerde P.

J Aerosol Med Pulm Drug Deliv. 2010 Oct;23(5):273-84. doi: 10.1089/jamp.2009.0790.

PMID:
20455769
4.

Prostaglandin modulation of airway inflammation and hyperresponsiveness in mice sensitized without adjuvant.

Swedin L, Ellis R, Neimert-Andersson T, Ryrfeldt A, Nilsson G, Inman M, Dahlén SE, Adner M.

Prostaglandins Other Lipid Mediat. 2010 Jun;92(1-4):44-53. doi: 10.1016/j.prostaglandins.2010.02.004. Epub 2010 Mar 7.

PMID:
20214998
5.

Vasoconstriction after inhalation of budesonide: a study in the isolated and perfused rat lung.

Ewing P, Ryrfeldt A, Sjöberg CO, Andersson P, Edsbäcker S, Gerde P.

Pulm Pharmacol Ther. 2010 Feb;23(1):9-14. doi: 10.1016/j.pupt.2009.09.004. Epub 2009 Sep 30.

PMID:
19800019
6.

Dissociation of airway inflammation and hyperresponsiveness by cyclooxygenase inhibition in allergen challenged mice.

Swedin L, Neimert-Andersson T, Hjoberg J, Jonasson S, van Hage M, Adner M, Ryrfeldt A, Dahlén SE.

Eur Respir J. 2009 Jul;34(1):200-8. doi: 10.1183/09031936.00030908. Epub 2009 Feb 27. Erratum in: Eur Respir J. 2009 Sep;34(3):784.

7.

Two different mechanisms for modulation of bronchoconstriction in guinea-pigs by cyclooxygenase metabolites.

Selg E, Andersson M, Låstbom L, Ryrfeldt A, Dahlén SE.

Prostaglandins Other Lipid Mediat. 2009 Apr;88(3-4):101-10. doi: 10.1016/j.prostaglandins.2008.11.003. Epub 2008 Dec 3.

PMID:
19103301
8.

Short inhalation exposures of the isolated and perfused rat lung to respirable dry particle aerosols; the detailed pharmacokinetics of budesonide, formoterol, and terbutaline.

Ewing P, Eirefelt SJ, Andersson P, Blomgren A, Ryrfeldt A, Gerde P.

J Aerosol Med Pulm Drug Deliv. 2008 Jun;21(2):169-80. doi: 10.1089/jamp.2007.0654.

PMID:
18518793
9.

Effects of selective and non-selective COX inhibitors on antigen-induced release of prostanoid mediators and bronchoconstriction in the isolated perfused and ventilated guinea pig lung.

Selg E, Låstbom L, Ryrfeldt A, Kumlin M, Dahlén SE.

Prostaglandins Leukot Essent Fatty Acids. 2008 Feb;78(2):89-97. doi: 10.1016/j.plefa.2008.01.001.

PMID:
18294831
10.

Antagonism of thromboxane receptors by diclofenac and lumiracoxib.

Selg E, Buccellati C, Andersson M, Rovati GE, Ezinga M, Sala A, Larsson AK, Ambrosio M, Låstbom L, Capra V, Dahlén B, Ryrfeldt A, Folco GC, Dahlén SE.

Br J Pharmacol. 2007 Dec;152(8):1185-95. Epub 2007 Oct 29. Erratum in: Br J Pharmacol. 2008 Apr;153(8):1763. Ambrosio, E [corrected to Ambrosio, M].

11.
12.

A novel method to aerosolize powder for short inhalation exposures at high concentrations: isolated rat lungs exposed to respirable diesel soot.

Gerde P, Ewing P, Låstbom L, Ryrfeldt A, Waher J, Lidén G.

Inhal Toxicol. 2004 Jan;16(1):45-52.

PMID:
14744664
13.

Increased airway responsiveness of a common fragrance component, 3-carene, after skin sensitisation--a study in isolated guinea pig lungs.

Låstbom L, Boman A, Johnsson S, Camner P, Ryrfeldt A.

Toxicol Lett. 2003 Nov 30;145(2):189-96.

PMID:
14581172
14.

Interactions among three classes of mediators explain antigen-induced bronchoconstriction in the isolated perfused and ventilated guinea pig lung.

Sundström E, Låstbom L, Ryrfeldt A, Dahlén SE.

J Pharmacol Exp Ther. 2003 Oct;307(1):408-18. Epub 2003 Sep 3.

PMID:
12954791
15.

A study of mechanisms underlying amitriptyline-induced acute lung function impairment.

Svens K, Ryrfeldt A.

Toxicol Appl Pharmacol. 2001 Dec 15;177(3):179-87.

PMID:
11749117
16.

Increased airway responsiveness after skin sensitisation to 3-carene, studied in isolated guinea pig lungs.

Låstbom L, Boman A, Camner P, Ryrfeldt A.

Toxicology. 2000 Jul 5;147(3):209-14.

PMID:
10924802
17.

Drug-induced inflammatory responses to the lung.

Ryrfeldt A.

Toxicol Lett. 2000 Mar 15;112-113:171-6. Review.

PMID:
10720728
18.

Amitriptyline-induced release of endothelin-1 in isolated perfused and ventilated rat lungs.

Dahlin KL, Mörtberg A, Låstbom L, Ryrfeldt A.

Pharmacol Toxicol. 1999 Dec;85(6):288-93.

PMID:
10628905
19.

Amitriptyline-induced loss of tight junction integrity in a human endothelial--smooth muscle cell bi-layer model.

Dahlin KL, Bohlin K, Strindlund J, Ryrfeldt A, Cotgreave IA.

Toxicology. 1999 Aug 13;136(1):1-13.

PMID:
10499846
20.

Does airway responsiveness increase after skin sensitisation to 3-carene: a study in isolated guinea pig lungs.

Låstbom L, Boman A, Camner P, Ryrfeldt A.

Toxicology. 1998 Jan 16;125(1):59-66.

PMID:
9585101
21.

Acute lung failure induced by tricyclic antidepressants.

Dahlin KL, Lâstbom L, Blomgren B, Ryrfeldt A.

Toxicol Appl Pharmacol. 1997 Oct;146(2):309-16.

PMID:
9344899
22.

Hexamethylene diisocyanate (HDI)-induced lung impairment: studies in isolated perfused and ventilated guinea pig lungs.

Låstbom L, Skarping G, Moldéus P, Ryrfeldt A.

Pharmacol Toxicol. 1997 Aug;81(2):85-9.

PMID:
9298505
23.

Sodium metabisulfite and citric acid induce bronchoconstriction via a sulfite-sensitive pathway in the isolated guinea pig lung.

Atzori L, Bannenberg G, Corriga AM, Congiu L, Lundberg JM, Moldèus P, Ryrfeldt A.

Respiration. 1997;64(2):145-51.

PMID:
9097350
24.

Analysis of the reactivity of [14C]toluene diisocyanate (TDI) in an isolated, perfused lung model.

Kennedy AL, Lastbom L, Skarping G, Dalene M, Ryrfeldt A, Moldeus P, Brown WE.

Chem Biol Interact. 1995 Nov 17;98(2):167-83.

PMID:
8548856
25.

Evidence for the activation of the signal-responsive phospholipase A2 by exogenous hydrogen peroxide.

Boyer CS, Bannenberg GL, Neve EP, Ryrfeldt A, Moldéus P.

Biochem Pharmacol. 1995 Sep 7;50(6):753-61.

PMID:
7575634
26.
27.

Characterization of bronchodilator effects and fate of S-nitrosothiols in the isolated perfused and ventilated guinea pig lung.

Bannenberg G, Xue J, Engman L, Cotgreave I, Moldéus P, Ryrfeldt A.

J Pharmacol Exp Ther. 1995 Mar;272(3):1238-45.

PMID:
7891339
28.

Mechanisms of 3-carene-induced bronchoconstriction in the isolated guinea pig lung.

Låstbom L, Falk-Filipsson A, Boyer S, Moldéus P, Ryrfeldt A.

Respiration. 1995;62(3):130-5.

PMID:
7569332
29.

Sensory neuropeptide-mediated bronchoconstriction of the guinea pig lung by diamide; a comparison to hydrogen peroxide.

Bannenberg G, Kimland M, Ryrfeldt A, Lundberg JM, Moldéus P.

Eur J Pharmacol. 1994 Apr 4;270(2-3):175-82.

PMID:
8039546
30.

Sulfur dioxide and sodium metabisulfite induce bronchoconstriction in the isolated perfused and ventilated guinea pig lung via stimulation of capsaicin-sensitive sensory nerves.

Bannenberg G, Atzori L, Xue J, Auberson S, Kimland M, Ryrfeldt A, Lundberg JM, Moldéus P.

Respiration. 1994;61(3):130-7.

PMID:
8047715
31.

Free radicals and lung disease.

Ryrfeldt A, Bannenberg G, Moldéus P.

Br Med Bull. 1993 Jul;49(3):588-603. Review.

PMID:
8221025
32.

Hydrogen peroxide-induced broncho- and vasoconstriction in the isolated perfused and ventilated guinea pig lung.

Bannenberg G, Kimland M, Ryrfeldt A, Moldeus P.

Pharmacol Toxicol. 1993 Apr-May;72(4-5):314-20.

PMID:
8372054
33.

Effects on lung function and metabolism of some air pollutants studied in isolated and perfused lungs.

Ryrfeldt A, Moldéus P.

Pharmacol Toxicol. 1993;72 Suppl 3:48-9. Review. No abstract available.

PMID:
8372064
34.
35.

Sulfur dioxide-induced bronchoconstriction in the isolated perfused and ventilated guinea-pig lung.

Atzori L, Bannenberg G, Corriga AM, Moldéus P, Ryrfeldt A.

Respiration. 1992;59(1):16-21.

PMID:
1579713
36.

Hypocalcemia induced by foscarnet (Foscavir) infusion in dogs.

Ryrfeldt A, Nordgren T, Lundström J.

Fundam Appl Toxicol. 1992 Jan;18(1):126-30.

PMID:
1534776
37.

Liver tumors in male rats following treatment with glucocorticosteroids.

Ryrfeldt A, Squire RA, Ekman L.

Toxicol Pathol. 1992;20(1):115-7.

PMID:
1411124
38.

Sulfur dioxide-induced bronchoconstriction via ruthenium red-sensitive activation of sensory nerves.

Atzori L, Bannenberg G, Corriga AM, Lou YP, Lundberg JM, Ryrfeldt A, Moldéus P.

Respiration. 1992;59(5):272-8.

PMID:
1283224
39.

Thiol modification in H2O2- and thromboxane-induced vaso- and bronchoconstriction in rat perfused lung.

Atzori L, Olafsdóttir K, Corriga AM, Bannenberg G, Ryrfeldt A, Moldéus P.

J Appl Physiol (1985). 1991 Oct;71(4):1309-14.

PMID:
1757354
40.

Hydroperoxide-induced broncho- and vasoconstriction in the isolated rat lung.

Olafsdottir K, Ryrfeldt A, Atzori L, Berggren M, Moldéus P.

Exp Lung Res. 1991 May-Jun;17(3):615-27.

PMID:
1860458
41.

Mechanisms of hydroperoxide-induced broncho- and vasoconstriction in isolated and perfused rat lung.

Olafsdóttir K, Atzori L, Ryrfeldt A, Berggren M, Kumlin M, Moldéus P.

Pharmacol Toxicol. 1991 Mar;68(3):181-6.

PMID:
1905406
42.

Rapid clearance of xanthines from airway and pulmonary tissues.

Kröll F, Karlsson JA, Nilsson E, Ryrfeldt A, Persson CG.

Am Rev Respir Dis. 1990 May;141(5 Pt 1):1167-71.

PMID:
2339839
43.

Effects of some autacoids on breathing and perfusion flow in the isolated perfused rat lung.

Ryrfeldt A, Olafsdottir K, Berggren M, Moldéus P.

Pharmacol Toxicol. 1990 Apr;66(4):312-4.

PMID:
2371237
44.

Drug induced esophageal lesions studied in vitro.

Ryrfeldt A, Norbeck K, Reiland S, Moldéus P.

Acta Physiol Scand Suppl. 1990;592:73-82.

PMID:
2267945
45.

Pulmonary disposition of the potent glucocorticoid budesonide, evaluated in an isolated perfused rat lung model.

Ryrfeldt A, Persson G, Nilsson E.

Biochem Pharmacol. 1989 Jan 1;38(1):17-22.

PMID:
2910298
46.

Bambuterol: uptake and metabolism in guinea pig isolated lungs.

Ryrfeldt A, Nilsson E, Tunek A, Svensson LA.

Pharm Res. 1988 Mar;5(3):151-5.

PMID:
3244626
47.
48.

Adenosine-induced bronchoconstriction in the guinea-pig isolated lung: interaction with theophylline and enprofylline.

Kröll F, Karlsson JA, Ryrfeldt A, Persson CG.

Pulm Pharmacol. 1988;1(2):85-92.

PMID:
2980292
49.

Metabolic acetal splitting of budesonide. A novel inactivation pathway for topical glucocorticoids.

Edsbäcker S, Andersson P, Lindberg C, Ryrfeldt A, Thalén A.

Drug Metab Dispos. 1987 May-Jun;15(3):412-7.

PMID:
2886320
50.

Liver metabolism of budesonide in rat, mouse, and man. Comparative aspects.

Edsbäcker S, Andersson P, Lindberg C, Paulson J, Ryrfeldt A, Thalén A.

Drug Metab Dispos. 1987 May-Jun;15(3):403-11.

PMID:
2886319

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