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Items: 1 to 50 of 68

1.

Crystal structures of aminotransferases Aro8 and Aro9 from Candida albicans and structural insights into their properties.

Kiliszek A, Rypniewski W, Rząd K, Milewski S, Gabriel I.

J Struct Biol. 2019 Mar 1;205(3):26-33. doi: 10.1016/j.jsb.2019.02.001. Epub 2019 Feb 8.

2.

Helix-loop-helix peptide foldamers and their use in the construction of hydrolase mimetics.

Drewniak M, Węglarz-Tomczak E, Ożga K, Rudzińska-Szostak E, Macegoniuk K, Tomczak JM, Bejger M, Rypniewski W, Berlicki Ł.

Bioorg Chem. 2018 Dec;81:356-361. doi: 10.1016/j.bioorg.2018.07.012. Epub 2018 Jul 17.

PMID:
30195249
3.

Crystal structures of nematode (parasitic T. spiralis and free living C. elegans), compared to mammalian, thymidylate synthases (TS). Molecular docking and molecular dynamics simulations in search for nematode-specific inhibitors of TS.

Jarmuła A, Wilk P, Maj P, Ludwiczak J, Dowierciał A, Banaszak K, Rypniewski W, Cieśla J, Dąbrowska M, Frączyk T, Bronowska AK, Jakowiecki J, Filipek S, Rode W.

J Mol Graph Model. 2017 Oct;77:33-50. doi: 10.1016/j.jmgm.2017.08.008. Epub 2017 Aug 12.

PMID:
28826032
4.

Stabilization of RNA hairpins using non-nucleotide linkers and circularization.

Kiliszek A, Blaszczyk L, Kierzek R, Rypniewski W.

Nucleic Acids Res. 2017 Jun 2;45(10):e92. doi: 10.1093/nar/gkx122.

5.

Structures of RNA repeats associated with neurological diseases.

Błaszczyk L, Rypniewski W, Kiliszek A.

Wiley Interdiscip Rev RNA. 2017 Jul;8(4). doi: 10.1002/wrna.1412. Epub 2017 Jan 28. Review.

PMID:
28130835
6.

Analysis of the complete genome sequence of the archaeon Pyrococcus chitonophagus DSM 10152 (formerly Thermococcus chitonophagus).

Papadimitriou K, Baharidis PK, Georgoulis A, Engel M, Louka M, Karamolegkou G, Tsoka A, Blom J, Pot B, Malecki P, Rypniewski W, Huber H, Schloter M, Vorgias C.

Extremophiles. 2016 May;20(3):351-61. doi: 10.1007/s00792-016-0826-x. Epub 2016 Mar 25.

PMID:
27016195
7.

The first crystal structures of RNA-PNA duplexes and a PNA-PNA duplex containing mismatches--toward anti-sense therapy against TREDs.

Kiliszek A, Banaszak K, Dauter Z, Rypniewski W.

Nucleic Acids Res. 2016 Feb 29;44(4):1937-43. doi: 10.1093/nar/gkv1513. Epub 2015 Dec 29.

8.

Watson-Crick-like pairs in CCUG repeats: evidence for tautomeric shifts or protonation.

Rypniewski W, Banaszak K, Kuliński T, Kiliszek A.

RNA. 2016 Jan;22(1):22-31. doi: 10.1261/rna.052399.115. Epub 2015 Nov 5.

9.

The stability of the TIM-barrel domain of a psychrophilic chitinase.

Stavros P, Malecki PH, Theodoridou M, Rypniewski W, Vorgias CE, Nounesis G.

Biochem Biophys Rep. 2015 Jul 30;3:108-116. doi: 10.1016/j.bbrep.2015.07.016. eCollection 2015 Sep.

10.

Crystal structure of mouse thymidylate synthase in tertiary complex with dUMP and raltitrexed reveals N-terminus architecture and two different active site conformations.

Dowierciał A, Wilk P, Rypniewski W, Rode W, Jarmuła A.

Biomed Res Int. 2014;2014:945803. doi: 10.1155/2014/945803. Epub 2014 Jun 3.

11.

Structural studies of CNG repeats.

Kiliszek A, Rypniewski W.

Nucleic Acids Res. 2014 Jul;42(13):8189-99. doi: 10.1093/nar/gku536. Epub 2014 Jun 17. Review.

12.

Crystal structures of substrate-bound chitinase from the psychrophilic bacterium Moritella marina and its structure in solution.

Malecki PH, Vorgias CE, Petoukhov MV, Svergun DI, Rypniewski W.

Acta Crystallogr D Biol Crystallogr. 2014 Mar;70(Pt 3):676-84. doi: 10.1107/S1399004713032264. Epub 2014 Feb 15.

PMID:
24598737
13.

Crystal structure of phosphoramide-phosphorylated thymidylate synthase reveals pSer127, reflecting probably pHis to pSer phosphotransfer.

Wilk P, Jarmuła A, Ruman T, Banaszak K, Rypniewski W, Cieśla J, Dowierciał A, Rode W.

Bioorg Chem. 2014 Feb;52:44-9. doi: 10.1016/j.bioorg.2013.11.003. Epub 2013 Nov 21.

PMID:
24321279
14.

Selectivity of Ni(II) and Zn(II) binding to Sporosarcina pasteurii UreE, a metallochaperone in the urease assembly: a calorimetric and crystallographic study.

Zambelli B, Banaszak K, Merloni A, Kiliszek A, Rypniewski W, Ciurli S.

J Biol Inorg Chem. 2013 Dec;18(8):1005-17. doi: 10.1007/s00775-013-1049-6. Epub 2013 Oct 15.

PMID:
24126709
15.

Structure of a complete four-domain chitinase from Moritella marina, a marine psychrophilic bacterium.

Malecki PH, Raczynska JE, Vorgias CE, Rypniewski W.

Acta Crystallogr D Biol Crystallogr. 2013 May;69(Pt 5):821-9. doi: 10.1107/S0907444913002011. Epub 2013 Apr 11.

PMID:
23633591
16.

Crystallographic characterization of CCG repeats.

Kiliszek A, Kierzek R, Krzyzosiak WJ, Rypniewski W.

Nucleic Acids Res. 2012 Sep;40(16):8155-62. doi: 10.1093/nar/gks557. Epub 2012 Jun 19.

17.

Binding of the plant hormone kinetin in the active site of Mistletoe Lectin I from Viscum album.

Małecki PH, Rypniewski W, Szymański M, Barciszewski J, Meyer A.

Biochim Biophys Acta. 2012 Feb;1824(2):334-8. doi: 10.1016/j.bbapap.2011.10.013. Epub 2011 Oct 28.

PMID:
22064121
18.

Crystallographic and X-ray absorption spectroscopic characterization of Helicobacter pylori UreE bound to Ni²⁺ and Zn²⁺ reveals a role for the disordered C-terminal arm in metal trafficking.

Banaszak K, Martin-Diaconescu V, Bellucci M, Zambelli B, Rypniewski W, Maroney MJ, Ciurli S.

Biochem J. 2012 Feb 1;441(3):1017-26. doi: 10.1042/BJ20111659.

19.

Crystal structures of CGG RNA repeats with implications for fragile X-associated tremor ataxia syndrome.

Kiliszek A, Kierzek R, Krzyzosiak WJ, Rypniewski W.

Nucleic Acids Res. 2011 Sep 1;39(16):7308-15. doi: 10.1093/nar/gkr368. Epub 2011 May 19.

20.

The crystal structures of eukaryotic phosphofructokinases from baker's yeast and rabbit skeletal muscle.

Banaszak K, Mechin I, Obmolova G, Oldham M, Chang SH, Ruiz T, Radermacher M, Kopperschläger G, Rypniewski W.

J Mol Biol. 2011 Mar 25;407(2):284-97. doi: 10.1016/j.jmb.2011.01.019. Epub 2011 Jan 15.

PMID:
21241708
21.

Crystallographic analysis of a thermoactive nitrilase.

Raczynska JE, Vorgias CE, Antranikian G, Rypniewski W.

J Struct Biol. 2011 Feb;173(2):294-302. doi: 10.1016/j.jsb.2010.11.017. Epub 2010 Nov 21.

PMID:
21095228
22.

Atomic resolution structure of CAG RNA repeats: structural insights and implications for the trinucleotide repeat expansion diseases.

Kiliszek A, Kierzek R, Krzyzosiak WJ, Rypniewski W.

Nucleic Acids Res. 2010 Dec;38(22):8370-6. doi: 10.1093/nar/gkq700. Epub 2010 Aug 11.

23.

Structural insights into CUG repeats containing the 'stretched U-U wobble': implications for myotonic dystrophy.

Kiliszek A, Kierzek R, Krzyzosiak WJ, Rypniewski W.

Nucleic Acids Res. 2009 Jul;37(12):4149-56. doi: 10.1093/nar/gkp350. Epub 2009 May 11.

24.

Structure of mistletoe lectin I from Viscum album in complex with the phytohormone zeatin.

Meyer A, Rypniewski W, Szymański M, Voelter W, Barciszewski J, Betzel C.

Biochim Biophys Acta. 2008 Nov;1784(11):1590-5. doi: 10.1016/j.bbapap.2008.07.010. Epub 2008 Jul 31.

PMID:
18718563
25.

Noncanonical G(syn)-G(anti) base pairs stabilized by sulphate anions in two X-ray structures of the (GUGGUCUGAUGAGGCC) RNA duplex.

Rypniewski W, Adamiak DA, Milecki J, Adamiak RW.

RNA. 2008 Sep;14(9):1845-51. doi: 10.1261/rna.1164308. Epub 2008 Jul 24.

26.

High resolution crystal structure of Rubrivivax gelatinosus cytochrome c'.

Benini S, Rypniewski WR, Wilson KS, Ciurli S.

J Inorg Biochem. 2008 May-Jun;102(5-6):1322-8. doi: 10.1016/j.jinorgbio.2008.01.017. Epub 2008 Jan 21.

PMID:
18295896
27.

The mistletoe lectin I--phloretamide structure reveals a new function of plant lectins.

Meyer A, Rypniewski W, Celewicz L, Erdmann VA, Voelter W, Singh TP, Genov N, Barciszewski J, Betzel Ch.

Biochem Biophys Res Commun. 2007 Dec 14;364(2):195-200. Epub 2007 Oct 5.

PMID:
17937929
28.

The crystal and solution studies of glucosamine-6-phosphate synthase from Candida albicans.

Raczynska J, Olchowy J, Konariev PV, Svergun DI, Milewski S, Rypniewski W.

J Mol Biol. 2007 Sep 21;372(3):672-88. Epub 2007 Jul 12.

PMID:
17681543
29.

Comparative crystallization and preliminary X-ray diffraction studies of locked nucleic acid and RNA stems of a tenascin C-binding aptamer.

Förster C, Brauer AB, Brode S, Schmidt KS, Perbandt M, Meyer A, Rypniewski W, Betzel C, Kurreck J, Fürste JP, Erdmann VA.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Jul 1;62(Pt 7):665-8. Epub 2006 Jun 10.

30.

The first crystal structure of an RNA racemate.

Rypniewski W, Vallazza M, Perbandt M, Klussmann S, Delucas LJ, Betzel C, Erdmann VA.

Acta Crystallogr D Biol Crystallogr. 2006 Jun;62(Pt 6):659-64. Epub 2006 May 12.

PMID:
16699193
31.

Crystallization and preliminary X-ray analysis of the isomerase domain of glucosamine-6-phosphate synthase from Candida albicans.

Olchowy J, Jedrzejczak R, Milewski S, Rypniewski W.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 Nov 1;61(Pt 11):994-6. Epub 2005 Oct 20.

32.

Synthetic human prion protein octapeptide repeat binds to the proteinase K active site.

Georgieva D, Rypniewski W, Echner H, Perbandt M, Koker M, Clos J, Redecke L, Bredehorst R, Voelter W, Genov N, Betzel C.

Biochem Biophys Res Commun. 2004 Dec 24;325(4):1406-11.

PMID:
15555583
33.

Structure of the reduced disulfide-bond isomerase DsbC from Escherichia coli.

Banaszak K, Mechin I, Frost G, Rypniewski W.

Acta Crystallogr D Biol Crystallogr. 2004 Oct;60(Pt 10):1747-52. Epub 2004 Sep 23.

PMID:
15388920
34.

Asp49 phospholipase A(2)-elaidoylamide complex: a new mode of inhibition.

Georgieva DN, Rypniewski W, Gabdoulkhakov A, Genov N, Betzel C.

Biochem Biophys Res Commun. 2004 Jul 9;319(4):1314-21.

PMID:
15194511
35.

Molecular details of urease inhibition by boric acid: insights into the catalytic mechanism.

Benini S, Rypniewski WR, Wilson KS, Mangani S, Ciurli S.

J Am Chem Soc. 2004 Mar 31;126(12):3714-5.

PMID:
15038715
36.

The X-ray structure of a snake venom Gln48 phospholipase A2 at 1.9A resolution reveals anion-binding sites.

Georgieva DN, Perbandt M, Rypniewski W, Hristov K, Genov N, Betzel C.

Biochem Biophys Res Commun. 2004 Mar 26;316(1):33-8.

PMID:
15003507
37.

First look at RNA in L-configuration.

Vallazza M, Perbandt M, Klussmann S, Rypniewski W, Einspahr HM, Erdmann VA, Betzel Ch.

Acta Crystallogr D Biol Crystallogr. 2004 Jan;60(Pt 1):1-7. Epub 2003 Dec 18.

PMID:
14684885
38.

The 10.8-A structure of Saccharomyces cerevisiae phosphofructokinase determined by cryoelectron microscopy: localization of the putative fructose 6-phosphate binding sites.

Ruiz T, Mechin I, Bär J, Rypniewski W, Kopperschläger G, Radermacher M.

J Struct Biol. 2003 Aug;143(2):124-34.

PMID:
12972349
39.

Trypsin revisited: crystallography AT (SUB) atomic resolution and quantum chemistry revealing details of catalysis.

Schmidt A, Jelsch C, Ostergaard P, Rypniewski W, Lamzin VS.

J Biol Chem. 2003 Oct 31;278(44):43357-62. Epub 2003 Aug 22.

40.

Crystallization and preliminary X-ray diffraction studies of a toxic phospholipase A2 from the venom of Vipera ammodytes meridionalis complexed to a synthetic inhibitor.

Georgieva DN, Rypniewski W, Perbandt M, Jain M, Genov N, Betzel C.

Biochim Biophys Acta. 2003 Aug 21;1650(1-2):1-3.

PMID:
12922163
41.

The structure of a functional unit from the wall of a gastropod hemocyanin offers a possible mechanism for cooperativity.

Perbandt M, Guthöhrlein EW, Rypniewski W, Idakieva K, Stoeva S, Voelter W, Genov N, Betzel C.

Biochemistry. 2003 Jun 3;42(21):6341-6.

PMID:
12767214
42.
43.

Crystallisation under microgravity of mistletoe lectin I from Viscum album with adenine monophosphate and the crystal structure at 1.9 A resolution.

Krauspenhaar R, Rypniewski W, Kalkura N, Moore K, DeLucas L, Stoeva S, Mikhailov A, Voelter W, Betzel Ch.

Acta Crystallogr D Biol Crystallogr. 2002 Oct;58(Pt 10 Pt 1):1704-7. Epub 2002 Sep 26.

PMID:
12351890
44.

Structure-based rationalization of urease inhibition by phosphate: novel insights into the enzyme mechanism.

Benini S, Rypniewski WR, Wilson KS, Ciurli S, Mangani S.

J Biol Inorg Chem. 2001 Oct;6(8):778-90.

PMID:
11713685
45.

Preliminary X-ray diffraction studies of the external functional unit RtH2-e from the Rapana thomasiana.

Perbandt M, Chandra V, Rajashankar KR, Idakieva K, Parvanova K, Rypniewski W, Stoeva S, Voelter W, Genov N, Betzel C.

Acta Crystallogr D Biol Crystallogr. 2001 Nov;57(Pt 11):1663-5. Epub 2001 Oct 25.

PMID:
11679737
46.

The 1.19 A X-ray structure of 2'-O-Me(CGCGCG)(2) duplex shows dehydrated RNA with 2-methyl-2,4-pentanediol in the minor groove.

Adamiak DA, Rypniewski WR, Milecki J, Adamiak RW.

Nucleic Acids Res. 2001 Oct 15;29(20):4144-53.

47.

Fusarium oxysporum trypsin at atomic resolution at 100 and 283 K: a study of ligand binding.

Rypniewski WR, Ostergaard PR, Nørregaard-Madsen M, Dauter M, Wilson KS.

Acta Crystallogr D Biol Crystallogr. 2001 Jan;57(Pt 1):8-19.

PMID:
11134922
48.

Crystal structure of oxidized Bacillus pasteurii cytochrome c553 at 0.97-A resolution.

Benini S, González A, Rypniewski WR, Wilson KS, Van Beeumen JJ, Ciurli S.

Biochemistry. 2000 Oct 31;39(43):13115-26.

PMID:
11052663
49.

The complex of Bacillus pasteurii urease with acetohydroxamate anion from X-ray data at 1.55 A resolution.

Benini S, Rypniewski WR, Wilson KS, Miletti S, Ciurli S, Mangani S.

J Biol Inorg Chem. 2000 Feb;5(1):110-8.

PMID:
10766443
50.

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