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Items: 45


Aetiology and outcomes of sepsis in adults in sub-Saharan Africa: a systematic review and meta-analysis.

Lewis JM, Feasey NA, Rylance J.

Crit Care. 2019 Jun 11;23(1):212. doi: 10.1186/s13054-019-2501-y.


Effect of antiretroviral therapy on longitudinal lung function trends in older children and adolescents with HIV-infection.

Rylance S, Rylance J, McHugh G, Majonga E, Bandason T, Mujuru H, Nathoo K, Rowland-Jones S, Henrion MYR, Simms V, Ferrand RA.

PLoS One. 2019 Mar 21;14(3):e0213556. doi: 10.1371/journal.pone.0213556. eCollection 2019.


Unexpectedly High Prevalence of Cytomegalovirus DNAemia in Older Children and Adolescents With Perinatally Acquired Human Immunodeficiency Virus Infection.

Yindom LM, Simms V, Majonga ED, McHugh G, Dauya E, Bandason T, Vincon H, Rylance J, Munyati S, Ferrand RA, Rowland-Jones SL.

Clin Infect Dis. 2019 Mar 4. pii: ciy961. doi: 10.1093/cid/ciy961. [Epub ahead of print]


Chronic lung disease in adult recurrent tuberculosis survivors in Zimbabwe: a cohort study.

Chin AT, Rylance J, Makumbirofa S, Meffert S, Vu T, Clayton J, Mason P, Woodruff P, Metcalfe J.

Int J Tuberc Lung Dis. 2019 Feb 1;23(2):203-211. doi: 10.5588/ijtld.18.0313.


Two Randomized Trials of the Effect of Live Attenuated Influenza Vaccine on Pneumococcal Colonization.

Rylance J, de Steenhuijsen Piters WAA, Mina MJ, Bogaert D, French N, Ferreira DM; EHPC-LAIV Study Group.

Am J Respir Crit Care Med. 2019 May 1;199(9):1160-1163. doi: 10.1164/rccm.201811-2081LE. No abstract available.


Pneumococcal Colonization in Healthy Adult Research Participants in the Conjugate Vaccine Era, United Kingdom, 2010-2017.

Adler H, Nikolaou E, Gould K, Hinds J, Collins AM, Connor V, Hales C, Hill H, Hyder-Wright AD, Zaidi SR, German EL, Gritzfeld JF, Mitsi E, Pojar S, Gordon SB, Roberts AP, Rylance J, Ferreira DM.

J Infect Dis. 2019 May 24;219(12):1989-1993. doi: 10.1093/infdis/jiz034.


Nasopharyngeal colonisation with Streptococcus pneumoniae in malnourished children: a systematic review and meta-analysis of prevalence.

Smith HC, German E, Ferreira DM, Rylance J.

Trans R Soc Trop Med Hyg. 2019 May 1;113(5):227-233. doi: 10.1093/trstmh/try139.


Validity of the qSOFA Score in Low- and Middle-Income Countries.

Lewis JM, Henrion M, Rylance J.

JAMA. 2018 Nov 20;320(19):2038-2039. doi: 10.1001/jama.2018.14473. No abstract available.


Inflammation induced by influenza virus impairs human innate immune control of pneumococcus.

Jochems SP, Marcon F, Carniel BF, Holloway M, Mitsi E, Smith E, Gritzfeld JF, Solórzano C, Reiné J, Pojar S, Nikolaou E, German EL, Hyder-Wright A, Hill H, Hales C, de Steenhuijsen Piters WAA, Bogaert D, Adler H, Zaidi S, Connor V, Gordon SB, Rylance J, Nakaya HI, Ferreira DM.

Nat Immunol. 2018 Dec;19(12):1299-1308. doi: 10.1038/s41590-018-0231-y. Epub 2018 Oct 29.


Hands are vehicles for transmission of Streptococcus pneumoniae in novel controlled human infection study.

Connor V, German E, Pojar S, Mitsi E, Hales C, Nikolaou E, Hyder-Wright A, Adler H, Zaidi S, Hill H, Jochems SP, Burhan H, French N, Tobery T, Rylance J, Ferreira DM.

Eur Respir J. 2018 Oct 10;52(4). pii: 1800599. doi: 10.1183/13993003.00599-2018. Print 2018 Oct. No abstract available.


The Early Recognition and Management of Sepsis in Sub-Saharan African Adults: A Systematic Review and Meta-Analysis.

Morton B, Stolbrink M, Kagima W, Rylance J, Mortimer K.

Int J Environ Res Public Health. 2018 Sep 15;15(9). pii: E2017. doi: 10.3390/ijerph15092017.


The African Sepsis Alliance: making a difference in the fight against sepsis in Africa.

Rylance J, Nsutebu E, Mergani KO, Grobusch MP, Jacob ST; African Sepsis Alliance.

Infection. 2018 Oct;46(5):733-734. doi: 10.1007/s15010-018-1184-7. Epub 2018 Aug 15. No abstract available.


Questionnaires for Lung Health in Africa across the Life Course.

Saleh S, van Zyl-Smit R, Allwood B, Lawin H, Mbatchou Ngahane BH, Ayakaka I, Moyo E, El-Sony A, Mortimer K, Rylance J.

Int J Environ Res Public Health. 2018 Jul 31;15(8). pii: E1615. doi: 10.3390/ijerph15081615.


Human alveolar macrophages predominately express combined classical M1 and M2 surface markers in steady state.

Mitsi E, Kamng'ona R, Rylance J, Solórzano C, Jesus Reiné J, Mwandumba HC, Ferreira DM, Jambo KC.

Respir Res. 2018 Apr 18;19(1):66. doi: 10.1186/s12931-018-0777-0.


Derivation and validation of a universal vital assessment (UVA) score: a tool for predicting mortality in adult hospitalised patients in sub-Saharan Africa.

Moore CC, Hazard R, Saulters KJ, Ainsworth J, Adakun SA, Amir A, Andrews B, Auma M, Baker T, Banura P, Crump JA, Grobusch MP, Huson MAM, Jacob ST, Jarrett OD, Kellett J, Lakhi S, Majwala A, Opio M, Rubach MP, Rylance J, Michael Scheld W, Schieffelin J, Ssekitoleko R, Wheeler I, Barnes LE.

BMJ Glob Health. 2017 Jul 28;2(2):e000344. doi: 10.1136/bmjgh-2017-000344. eCollection 2017.


Human Immunodeficiency Virus-Associated Chronic Lung Disease in Children and Adolescents in Zimbabwe: Chest Radiographic and High-Resolution Computed Tomographic Findings.

Desai SR, Nair A, Rylance J, Mujuru H, Nathoo K, McHugh G, Majonga E, Metcalfe J, Kranzer K, Ferrand RA.

Clin Infect Dis. 2018 Jan 6;66(2):274-281. doi: 10.1093/cid/cix778.


A framework for Controlled Human Infection Model (CHIM) studies in Malawi: Report of a Wellcome Trust workshop on CHIM in Low Income Countries held in Blantyre, Malawi.

Gordon SB, Rylance J, Luck A, Jambo K, Ferreira DM, Manda-Taylor L, Bejon P, Ngwira B, Littler K, Seager Z, Gibani M, Gmeiner M, Roestenberg M, Mlombe Y; Wellcome Trust CHIM workshop participants.

Wellcome Open Res. 2017 Aug 24;2:70. doi: 10.12688/wellcomeopenres.12256.1. eCollection 2017.


Single use and conventional bronchoscopes for Broncho alveolar lavage (BAL) in research: a comparative study (NCT 02515591).

Zaidi SR, Collins AM, Mitsi E, Reiné J, Davies K, Wright AD, Owugha J, Fitzgerald R, Ganguli A, Gordon SB, Ferreira DM, Rylance J.

BMC Pulm Med. 2017 May 5;17(1):83. doi: 10.1186/s12890-017-0421-7.


Pneumococcal Capsular Polysaccharide Immunity in the Elderly.

Adler H, Ferreira DM, Gordon SB, Rylance J.

Clin Vaccine Immunol. 2017 Jun 5;24(6). pii: e00004-17. doi: 10.1128/CVI.00004-17. Print 2017 Jun. Review.


Novel Analysis of Immune Cells from Nasal Microbiopsy Demonstrates Reliable, Reproducible Data for Immune Populations, and Superior Cytokine Detection Compared to Nasal Wash.

Jochems SP, Piddock K, Rylance J, Adler H, Carniel BF, Collins A, Gritzfeld JF, Hancock C, Hill H, Reiné J, Seddon A, Solórzano C, Sunny S, Trimble A, Wright AD, Zaidi S, Gordon SB, Ferreira DM.

PLoS One. 2017 Jan 20;12(1):e0169805. doi: 10.1371/journal.pone.0169805. eCollection 2017.


Community-Acquired Pneumonia in Sub-Saharan Africa.

Aston SJ, Rylance J.

Semin Respir Crit Care Med. 2016 Dec;37(6):855-867. Epub 2016 Dec 13.


Chronic lung disease in HIV-infected children established on antiretroviral therapy.

Rylance J, Mchugh G, Metcalfe J, Mujuru H, Nathoo K, Wilmore S, Rowland-Jones S, Majonga E, Kranzer K, Ferrand RA.

AIDS. 2016 Nov 28;30(18):2795-2803.


Household air pollution and the lung microbiome of healthy adults in Malawi: a cross-sectional study.

Rylance J, Kankwatira A, Nelson DE, Toh E, Day RB, Lin H, Gao X, Dong Q, Sodergren E, Weinstock GM, Heyderman RS, Twigg HL 3rd, Gordon SB.

BMC Microbiol. 2016 Aug 11;16(1):182. doi: 10.1186/s12866-016-0803-7.


Chronic Morbidity Among Older Children and Adolescents at Diagnosis of HIV Infection.

McHugh G, Rylance J, Mujuru H, Nathoo K, Chonzi P, Dauya E, Bandason T, Simms V, Kranzer K, Ferrand RA.

J Acquir Immune Defic Syndr. 2016 Nov 1;73(3):275-281.


Global Considerations in Human Immunodeficiency Virus-Associated Respiratory Disease.

Rylance J, Meghji J, Miller RF, Ferrand RA.

Semin Respir Crit Care Med. 2016 Apr;37(2):166-80. doi: 10.1055/s-0036-1572555. Epub 2016 Mar 14. Review.


Comparison of methods for the analysis of airway macrophage particulate load from induced sputum, a potential biomarker of air pollution exposure.

Jary H, Rylance J, Patel L, Gordon SB, Mortimer K.

BMC Pulm Med. 2015 Nov 5;15:137. doi: 10.1186/s12890-015-0135-7.


Clinical Characteristics and Lung Function in Older Children Vertically Infected With Human Immunodeficiency Virus in Malawi.

Mwalukomo T, Rylance SJ, Webb EL, Anderson S, O'Hare B, van Oosterhout JJ, Ferrand RA, Corbett EL, Rylance J.

J Pediatric Infect Dis Soc. 2016 Jun;5(2):161-9. doi: 10.1093/jpids/piv045. Epub 2015 Aug 25.


Chronic Household Air Pollution Exposure Is Associated with Impaired Alveolar Macrophage Function in Malawian Non-Smokers.

Rylance J, Chimpini C, Semple S, Russell DG, Jackson MJ, Heyderman RS, Gordon SB.

PLoS One. 2015 Sep 25;10(9):e0138762. doi: 10.1371/journal.pone.0138762. eCollection 2015.


Are we failing our trainees in providing opportunities to attain procedural confidence?

Lagan J, Cutts L, Zaidi S, Benton I, Rylance J.

Br J Hosp Med (Lond). 2015 Feb;76(2):105-8. doi: 10.12968/hmed.2015.76.2.105.


Measuring the true impact of an electronic physiological surveillance system (EPSS).

Shaw D, Blakey J, Rylance J.

BMJ Qual Saf. 2015 Feb;24(2):175-6. doi: 10.1136/bmjqs-2014-003804. No abstract available.


Household air pollution causes dose-dependent inflammation and altered phagocytosis in human macrophages.

Rylance J, Fullerton DG, Scriven J, Aljurayyan AN, Mzinza D, Barrett S, Wright AK, Wootton DG, Glennie SJ, Baple K, Knott A, Mortimer K, Russell DG, Heyderman RS, Gordon SB.

Am J Respir Cell Mol Biol. 2015 May;52(5):584-93. doi: 10.1165/rcmb.2014-0188OC.


Respiratory risks from household air pollution in low and middle income countries.

Gordon SB, Bruce NG, Grigg J, Hibberd PL, Kurmi OP, Lam KB, Mortimer K, Asante KP, Balakrishnan K, Balmes J, Bar-Zeev N, Bates MN, Breysse PN, Buist S, Chen Z, Havens D, Jack D, Jindal S, Kan H, Mehta S, Moschovis P, Naeher L, Patel A, Perez-Padilla R, Pope D, Rylance J, Semple S, Martin WJ 2nd.

Lancet Respir Med. 2014 Oct;2(10):823-60. doi: 10.1016/S2213-2600(14)70168-7. Epub 2014 Sep 2. Review.


Bronchoalveolar lavage (BAL) for research; obtaining adequate sample yield.

Collins AM, Rylance J, Wootton DG, Wright AD, Wright AK, Fullerton DG, Gordon SB.

J Vis Exp. 2014 Mar 24;(85). doi: 10.3791/4345.


Sickle-cell disease in Malawian children is associated with restrictive spirometry: a cross-sectional survey.

Cook J, Jefferis O, Matchere P, Mbale E, Rylance J.

Int J Tuberc Lung Dis. 2013 Sep;17(9):1235-8. doi: 10.5588/ijtld.12.0965. Epub 2013 Jul 3.


Immunoactivating peptide p4 augments alveolar macrophage phagocytosis in two diverse human populations.

Bangert M, Wright AK, Rylance J, Kelly MJ, Wright AD, Carlone GM, Sampson JS, Rajam G, Ades EW, Kadioglu A, Gordon SB.

Antimicrob Agents Chemother. 2013 Sep;57(9):4566-9. doi: 10.1128/AAC.00742-13. Epub 2013 Jul 1.


Early warning scores generated in developed healthcare settings are not sufficient at predicting early mortality in Blantyre, Malawi: a prospective cohort study.

Wheeler I, Price C, Sitch A, Banda P, Kellett J, Nyirenda M, Rylance J.

PLoS One. 2013;8(3):e59830. doi: 10.1371/journal.pone.0059830. Epub 2013 Mar 29. Erratum in: PLoS One. 2014;9(2):e91623.


Household air pollution: a call for studies into biomarkers of exposure and predictors of respiratory disease.

Rylance J, Gordon SB, Naeher LP, Patel A, Balmes JR, Adetona O, Rogalsky DK, Martin WJ 2nd.

Am J Physiol Lung Cell Mol Physiol. 2013 May 1;304(9):L571-8. doi: 10.1152/ajplung.00416.2012. Epub 2013 Mar 1.


Case report--progressive immobilising back and joint pain.

Divala T, Rylance J.

Malawi Med J. 2011 Jun;23(2):58-9. No abstract available.


Priorities for tuberculosis research: a systematic review.

Rylance J, Pai M, Lienhardt C, Garner P.

Lancet Infect Dis. 2010 Dec;10(12):886-92. doi: 10.1016/S1473-3099(10)70201-2. Epub 2010 Nov 1. Review.


Acute exposure of mice to high-dose ultrafine carbon black decreases susceptibility to pneumococcal pneumonia.

Tellabati A, Fernandes VE, Teichert F, Singh R, Rylance J, Gordon S, Andrew PW, Grigg J.

Part Fibre Toxicol. 2010 Oct 19;7:30. doi: 10.1186/1743-8977-7-30.


The global burden of air pollution on mortality: the need to include exposure to household biomass fuel-derived particulates.

Rylance J, Fullerton DG, Semple S, Ayres JG.

Environ Health Perspect. 2010 Oct;118(10):A424; author reply A424-5. doi: 10.1289/ehp.1002397. No abstract available.


Where there's smoke... there's tuberculosis.

Gordon S, Rylance J.

Thorax. 2009 Aug;64(8):649-50. doi: 10.1136/thx.2009.116400. No abstract available.


Use of an early warning score and ability to walk predicts mortality in medical patients admitted to hospitals in Tanzania.

Rylance J, Baker T, Mushi E, Mashaga D.

Trans R Soc Trop Med Hyg. 2009 Aug;103(8):790-4. doi: 10.1016/j.trstmh.2009.05.004. Epub 2009 Jun 21.


Measles and rubella immunisation: information and consent in children.

Rylance G, Bowen C, Rylance J.

BMJ. 1995 Oct 7;311(7010):923-4. No abstract available.

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