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Items: 1 to 50 of 181

1.

Access to rehabilitation services for older adults living with dementia or in a residential aged care facility following a hip fracture: healthcare professionals' views.

Mitchell R, Fajardo Pulido D, Ryder T, Norton G, Brodaty H, Draper B, Close J, Rapport F, Lystad R, Harris I, Harvey L, Sherrington C, Cameron ID, Braithwaite J.

Disabil Rehabil. 2019 Jul 23:1-12. doi: 10.1080/09638288.2019.1643418. [Epub ahead of print]

PMID:
31335212
2.

Role of Molybdenum-Containing Enzymes in the Biotransformation of the Novel Ghrelin Receptor Inverse Agonist PF-5190457: A Reverse Translational Bed-to-Bench Approach.

Adusumalli S, Jamwal R, Obach RS, Ryder TF, Leggio L, Akhlaghi F.

Drug Metab Dispos. 2019 Aug;47(8):874-882. doi: 10.1124/dmd.119.087015. Epub 2019 Jun 10.

3.

A Three-dimensional Ex Vivo Viability Assay Reveals a Strong Correlation Between Response to Targeted Inhibitors and Mutation Status in Melanoma Lymph Node Metastases.

Flørenes VA, Flem-Karlsen K, McFadden E, Bergheim IR, Nygaard V, Nygård V, Farstad IN, Øy GF, Emilsen E, Giller-Fleten K, Ree AH, Flatmark K, Gullestad HP, Hermann R, Ryder T, Wernhoff P, Mælandsmo GM.

Transl Oncol. 2019 Jul;12(7):951-958. doi: 10.1016/j.tranon.2019.04.001. Epub 2019 May 13.

4.

Dynamic network partnerships and social contagion drive cooperation.

Dakin R, Ryder TB.

Proc Biol Sci. 2018 Dec 19;285(1893):20181973. doi: 10.1098/rspb.2018.1973.

PMID:
30963888
5.

Skin Quality Improvement With VYC-12, a New Injectable Hyaluronic Acid: Objective Results Using Digital Analysis.

Cavallini M, Papagni M, Ryder TJ, Patalano M.

Dermatol Surg. 2019 Mar 18. doi: 10.1097/DSS.0000000000001932. [Epub ahead of print]

PMID:
30893167
6.

Gene expression in the social behavior network of the wire-tailed manakin (Pipra filicauda) brain.

Horton BM, Ryder TB, Moore IT, Balakrishnan CN.

Genes Brain Behav. 2019 Feb 12:e12560. doi: 10.1111/gbb.12560. [Epub ahead of print]

PMID:
30756473
7.

Distribution, Metabolism, and Excretion of Gedatolisib in Healthy Male Volunteers After a Single Intravenous Infusion.

Houk BE, Alvey CW, Visswanathan R, Kirkovsky L, Matschke KT, Kimoto E, Ryder T, Obach RS, Durairaj C.

Clin Pharmacol Drug Dev. 2019 Jan;8(1):22-31. doi: 10.1002/cpdd.615. Epub 2018 Sep 26.

PMID:
30256541
8.

Sampling baseline androgens in free-living passerines: Methodological considerations and solutions.

Vernasco BJ, Horton BM, Ryder TB, Moore IT.

Gen Comp Endocrinol. 2019 Mar 1;273:202-208. doi: 10.1016/j.ygcen.2018.07.017. Epub 2018 Jul 26.

PMID:
30056137
9.

Acyl Glucuronide Metabolites of 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1 H-indole-3-carboxylic Acid (PF-06409577) and Related Indole-3-carboxylic Acid Derivatives are Direct Activators of Adenosine Monophosphate-Activated Protein Kinase (AMPK).

Ryder TF, Calabrese MF, Walker GS, Cameron KO, Reyes AR, Borzilleri KA, Delmore J, Miller R, Kurumbail RG, Ward J, Kung DW, Brown JA, Edmonds DJ, Eng H, Wolford AC, Kalgutkar AS.

J Med Chem. 2018 Aug 23;61(16):7273-7288. doi: 10.1021/acs.jmedchem.8b00807. Epub 2018 Aug 2.

PMID:
30036059
10.

Tales of testosterone: Advancing our understanding of environmental endocrinology through studies of neotropical birds.

Moore IT, Vernasco BJ, Escallón C, Small TW, Ryder TB, Horton BM.

Gen Comp Endocrinol. 2019 Mar 1;273:184-191. doi: 10.1016/j.ygcen.2018.07.003. Epub 2018 Jul 7. Review.

PMID:
29990493
11.

Discovery of a Novel Small-Molecule Modulator of C-X-C Chemokine Receptor Type 7 as a Treatment for Cardiac Fibrosis.

Menhaji-Klotz E, Hesp KD, Londregan AT, Kalgutkar AS, Piotrowski DW, Boehm M, Song K, Ryder T, Beaumont K, Jones RM, Atkinson K, Brown JA, Litchfield J, Xiao J, Canterbury DP, Burford K, Thuma BA, Limberakis C, Jiao W, Bagley SW, Agarwal S, Crowell D, Pazdziorko S, Ward J, Price DA, Clerin V.

J Med Chem. 2018 Apr 26;61(8):3685-3696. doi: 10.1021/acs.jmedchem.8b00190. Epub 2018 Apr 17.

PMID:
29627981
12.

Vertical Rectus Abdominis Musculocutaneous Flap Repair Improves Perineal Wound Healing after Abdominoperineal Resection for Irradiated Locally Advanced Rectal Cancer.

Spasojevic M, Mariathasan AB, Goscinski M, Thorgersen EB, Solbakken AM, Gullestad HP, Ryder T, Flatmark K, Larsen SG.

Ann Surg Oncol. 2018 May;25(5):1357-1365. doi: 10.1245/s10434-018-6363-3. Epub 2018 Mar 1.

PMID:
29497909
13.

Characterizing selection in black-throated blue warblers using a sexual network approach.

Cramer ERA, Kaiser SA, Webster MS, Sillett TS, Ryder TB.

J Evol Biol. 2017 Dec;30(12):2177-2188. doi: 10.1111/jeb.13183. Epub 2017 Oct 25.

PMID:
28986958
14.

Spatial and temporal drivers of avian population dynamics across the annual cycle.

Rushing CS, Hostetler JA, Sillett TS, Marra PP, Rotenberg JA, Ryder TB.

Ecology. 2017 Nov;98(11):2837-2850. doi: 10.1002/ecy.1967. Epub 2017 Sep 7.

PMID:
28756623
15.

Characterization of TAP Ambr 250 disposable bioreactors, as a reliable scale-down model for biologics process development.

Xu P, Clark C, Ryder T, Sparks C, Zhou J, Wang M, Russell R, Scott C.

Biotechnol Prog. 2017 Mar;33(2):478-489. doi: 10.1002/btpr.2417. Epub 2017 Feb 6.

PMID:
27977912
16.

A Scalable Total Synthesis of (-)-Nakadomarin A.

Boeckman RK Jr, Wang H, Rugg KW, Genung NE, Chen K, Ryder TR.

Org Lett. 2016 Dec 2;18(23):6136-6139. Epub 2016 Nov 11.

PMID:
27934385
17.

Discovery and Preclinical Characterization of 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1H-indole-3-carboxylic Acid (PF-06409577), a Direct Activator of Adenosine Monophosphate-activated Protein Kinase (AMPK), for the Potential Treatment of Diabetic Nephropathy.

Cameron KO, Kung DW, Kalgutkar AS, Kurumbail RG, Miller R, Salatto CT, Ward J, Withka JM, Bhattacharya SK, Boehm M, Borzilleri KA, Brown JA, Calabrese M, Caspers NL, Cokorinos E, Conn EL, Dowling MS, Edmonds DJ, Eng H, Fernando DP, Frisbie R, Hepworth D, Landro J, Mao Y, Rajamohan F, Reyes AR, Rose CR, Ryder T, Shavnya A, Smith AC, Tu M, Wolford AC, Xiao J.

J Med Chem. 2016 Sep 8;59(17):8068-81. doi: 10.1021/acs.jmedchem.6b00866. Epub 2016 Aug 20.

PMID:
27490827
18.

Fibromatosis in vertical rectus abdominis myocutaneous flap imitating tumor recurrence after surgery for locally advanced rectal cancer: case report.

Goscinski MA, Hole KH, Tønne E, Ryder T, Grøholt KK, Flatmark K.

World J Surg Oncol. 2016 Mar 3;14:63. doi: 10.1186/s12957-016-0818-4.

19.

Quantifying drivers of population dynamics for a migratory bird throughout the annual cycle.

Rushing CS, Ryder TB, Marra PP.

Proc Biol Sci. 2016 Jan 27;283(1823). pii: 20152846. doi: 10.1098/rspb.2015.2846.

20.

Climate, demography and lek stability in an Amazonian bird.

Ryder TB, Sillett TS.

Proc Biol Sci. 2016 Jan 27;283(1823). pii: 20152314. doi: 10.1098/rspb.2015.2314.

21.

Pharmacokinetics and Disposition of the Thiouracil Derivative PF-06282999, an Orally Bioavailable, Irreversible Inactivator of Myeloperoxidase Enzyme, Across Animals and Humans.

Dong JQ, Varma MV, Wolford A, Ryder T, Di L, Feng B, Terra SG, Sagawa K, Kalgutkar AS.

Drug Metab Dispos. 2016 Feb;44(2):209-19. doi: 10.1124/dmd.115.067868. Epub 2015 Nov 25.

PMID:
26608081
22.

Experimental resource pulses influence social-network dynamics and the potential for information flow in tool-using crows.

St Clair JJH, Burns ZT, Bettaney EM, Morrissey MB, Otis B, Ryder TB, Fleischer RC, James R, Rutz C.

Nat Commun. 2015 Nov 3;6:7197. doi: 10.1038/ncomms8197.

23.

Discovery of 2-(6-(5-Chloro-2-methoxyphenyl)-4-oxo-2-thioxo-3,4-dihydropyrimidin-1(2H)-yl)acetamide (PF-06282999): A Highly Selective Mechanism-Based Myeloperoxidase Inhibitor for the Treatment of Cardiovascular Diseases.

Ruggeri RB, Buckbinder L, Bagley SW, Carpino PA, Conn EL, Dowling MS, Fernando DP, Jiao W, Kung DW, Orr ST, Qi Y, Rocke BN, Smith A, Warmus JS, Zhang Y, Bowles D, Widlicka DW, Eng H, Ryder T, Sharma R, Wolford A, Okerberg C, Walters K, Maurer TS, Zhang Y, Bonin PD, Spath SN, Xing G, Hepworth D, Ahn K, Kalgutkar AS.

J Med Chem. 2015 Nov 12;58(21):8513-28. doi: 10.1021/acs.jmedchem.5b00963. Epub 2015 Oct 28.

PMID:
26509551
24.

Chemical and computational methods for the characterization of covalent reactive groups for the prospective design of irreversible inhibitors.

Flanagan ME, Abramite JA, Anderson DP, Aulabaugh A, Dahal UP, Gilbert AM, Li C, Montgomery J, Oppenheimer SR, Ryder T, Schuff BP, Uccello DP, Walker GS, Wu Y, Brown MF, Chen JM, Hayward MM, Noe MC, Obach RS, Philippe L, Shanmugasundaram V, Shapiro MJ, Starr J, Stroh J, Che Y.

J Med Chem. 2014 Dec 11;57(23):10072-9. doi: 10.1021/jm501412a. Epub 2014 Nov 26.

PMID:
25375838
25.

Biosynthesis of drug metabolites and quantitation using NMR spectroscopy for use in pharmacologic and drug metabolism studies.

Walker GS, Bauman JN, Ryder TF, Smith EB, Spracklin DK, Obach RS.

Drug Metab Dispos. 2014 Oct;42(10):1627-39. doi: 10.1124/dmd.114.059204. Epub 2014 Jul 22.

PMID:
25053618
26.

Connectivity of wood thrush breeding, wintering, and migration sites based on range-wide tracking.

Stanley CQ, McKinnon EA, Fraser KC, Macpherson MP, Casbourn G, Friesen L, Marra PP, Studds C, Ryder TB, Diggs NE, Stutchbury BJ.

Conserv Biol. 2015 Feb;29(1):164-74. doi: 10.1111/cobi.12352. Epub 2014 Jul 22.

PMID:
25052795
27.

Assessing migratory connectivity for a long-distance migratory bird using multiple intrinsic markers.

Rushing CS, Ryder TB, Saracco JF, Marra PP.

Ecol Appl. 2014 Apr;24(3):445-56.

PMID:
24834732
28.

The pharmacokinetics, metabolism, and clearance mechanisms of tofacitinib, a janus kinase inhibitor, in humans.

Dowty ME, Lin J, Ryder TF, Wang W, Walker GS, Vaz A, Chan GL, Krishnaswami S, Prakash C.

Drug Metab Dispos. 2014 Apr;42(4):759-73. doi: 10.1124/dmd.113.054940. Epub 2014 Jan 24.

PMID:
24464803
29.

Decay of interspecific avian flock networks along a disturbance gradient in Amazonia.

Mokross K, Ryder TB, Côrtes MC, Wolfe JD, Stouffer PC.

Proc Biol Sci. 2013 Dec 11;281(1776):20132599. doi: 10.1098/rspb.2013.2599. Print 2014 Feb 7.

30.

Impaired steroidogenesis and apoptosis of granulosa-luteal cells in primary culture induced by cis-platinum.

Chatterjee R, Helal M, Mobberley M, Ryder T, Bajoria R.

Am J Obstet Gynecol. 2014 Mar;210(3):252.e1-7. doi: 10.1016/j.ajog.2013.11.014. Epub 2013 Nov 8.

PMID:
24215857
31.

Synthesis of quaternary α-amino acid-based arginase inhibitors via the Ugi reaction.

Golebiowski A, Whitehouse D, Beckett RP, Van Zandt M, Ji MK, Ryder TR, Jagdmann E, Andreoli M, Lee Y, Sheeler R, Conway B, Olczak J, Mazur M, Czestkowski W, Piotrowska W, Cousido-Siah A, Ruiz FX, Mitschler A, Podjarny A, Schroeter H.

Bioorg Med Chem Lett. 2013 Sep 1;23(17):4837-41. doi: 10.1016/j.bmcl.2013.06.092. Epub 2013 Jul 8.

PMID:
23886684
32.

Transient exposure to low levels of insecticide affects metabolic networks of honeybee larvae.

Derecka K, Blythe MJ, Malla S, Genereux DP, Guffanti A, Pavan P, Moles A, Snart C, Ryder T, Ortori CA, Barrett DA, Schuster E, Stöger R.

PLoS One. 2013 Jul 2;8(7):e68191. doi: 10.1371/journal.pone.0068191. Print 2013.

33.

Estimates of dietary overlap for six species of Amazonian manakin birds using stable isotopes.

Fair JM, Ryder TB, Loiselle BA, Blake JG, Larson TE, Davis P, Syme J, Perkins GB, Heikoop JM.

Isotopes Environ Health Stud. 2013;49(3):420-35. doi: 10.1080/10256016.2013.784702. Epub 2013 Jun 20.

PMID:
23781884
34.

Reactive metabolite trapping studies on imidazo- and 2-methylimidazo[2,1-b]thiazole-based inverse agonists of the ghrelin receptor.

Kalgutkar AS, Ryder TF, Walker GS, Orr ST, Cabral S, Goosen TC, Lapham K, Eng H.

Drug Metab Dispos. 2013 Jul;41(7):1375-88. doi: 10.1124/dmd.113.051839. Epub 2013 Apr 22.

PMID:
23610086
35.

Metabolism of a serotonin-4 receptor partial agonist 4-{4-[4-tetrahydrofuran-3-yloxy)-benzo[d]isoxazol-3-yloxymethyl]-piperidin-1-ylmethyl}-tetrahydropyran-4-ol (TBPT): identification of an unusual pharmacologically active cyclized oxazolidine metabolite in human.

Sawant-Basak A, Coffman KJ, Walker GS, Ryder TF, Tseng E, Miller E, Lee C, Vanase-Frawley MA, Wong JW, Brodney MA, Rapp T, Obach RS.

J Pharm Sci. 2013 Sep;102(9):3277-93. doi: 10.1002/jps.23542. Epub 2013 Apr 15.

PMID:
23589342
36.

Discovery of (R)-2-amino-6-borono-2-(2-(piperidin-1-yl)ethyl)hexanoic acid and congeners as highly potent inhibitors of human arginases I and II for treatment of myocardial reperfusion injury.

Van Zandt MC, Whitehouse DL, Golebiowski A, Ji MK, Zhang M, Beckett RP, Jagdmann GE, Ryder TR, Sheeler R, Andreoli M, Conway B, Mahboubi K, D'Angelo G, Mitschler A, Cousido-Siah A, Ruiz FX, Howard EI, Podjarny AD, Schroeter H.

J Med Chem. 2013 Mar 28;56(6):2568-80. doi: 10.1021/jm400014c. Epub 2013 Mar 8.

PMID:
23472952
37.

2-Substituted-2-amino-6-boronohexanoic acids as arginase inhibitors.

Golebiowski A, Paul Beckett R, Van Zandt M, Ji MK, Whitehouse D, Ryder TR, Jagdmann E, Andreoli M, Mazur A, Padmanilayam M, Cousido-Siah A, Mitschler A, Ruiz FX, Podjarny A, Schroeter H.

Bioorg Med Chem Lett. 2013 Apr 1;23(7):2027-30. doi: 10.1016/j.bmcl.2013.02.024. Epub 2013 Feb 13.

PMID:
23453840
38.

Insights into the novel hydrolytic mechanism of a diethyl 2-phenyl-2-(2-arylacetoxy)methyl malonate ester-based microsomal triglyceride transfer protein (MTP) inhibitor.

Ryder T, Walker GS, Goosen TC, Ruggeri RB, Conn EL, Rocke BN, Lapham K, Steppan CM, Hepworth D, Kalgutkar AS.

Chem Res Toxicol. 2012 Oct 15;25(10):2138-52. doi: 10.1021/tx300243v. Epub 2012 Sep 27.

PMID:
22989032
39.

Metabolism, excretion, and pharmacokinetics of ((3,3-difluoropyrrolidin-1-yl)((2S,4S)-4-(4-(pyrimidin-2-yl)piperazin-1-yl)pyrrolidin-2-yl)methanone, a dipeptidyl peptidase inhibitor, in rat, dog and human.

Sharma R, Sun H, Piotrowski DW, Ryder TF, Doran SD, Dai H, Prakash C.

Drug Metab Dispos. 2012 Nov;40(11):2143-61. doi: 10.1124/dmd.112.047316. Epub 2012 Aug 15.

PMID:
22896728
40.

Proximity data-loggers increase the quantity and quality of social network data.

Ryder TB, Horton BM, van den Tillaart M, Morales Jde D, Moore IT.

Biol Lett. 2012 Dec 23;8(6):917-20. doi: 10.1098/rsbl.2012.0536. Epub 2012 Aug 1.

41.

The ecological-evolutionary interplay: density-dependent sexual selection in a migratory songbird.

Ryder TB, Fleischer RC, Shriver WG, Marra PP.

Ecol Evol. 2012 May;2(5):976-87. doi: 10.1002/ece3.254.

42.

Restricted gene flow and fine-scale population structuring in tool using New Caledonian crows.

Rutz C, Ryder TB, Fleischer RC.

Naturwissenschaften. 2012 Apr;99(4):313-20. doi: 10.1007/s00114-012-0904-6. Epub 2012 Mar 15.

PMID:
22418860
43.

Optimized assays for human UDP-glucuronosyltransferase (UGT) activities: altered alamethicin concentration and utility to screen for UGT inhibitors.

Walsky RL, Bauman JN, Bourcier K, Giddens G, Lapham K, Negahban A, Ryder TF, Obach RS, Hyland R, Goosen TC.

Drug Metab Dispos. 2012 May;40(5):1051-65. doi: 10.1124/dmd.111.043117. Epub 2012 Feb 22.

PMID:
22357286
44.

Characterization and significance of adhesion and junction-related proteins in mouse ovarian follicles.

Mora JM, Fenwick MA, Castle L, Baithun M, Ryder TA, Mobberley M, Carzaniga R, Franks S, Hardy K.

Biol Reprod. 2012 May 17;86(5):153, 1-14. doi: 10.1095/biolreprod.111.096156. Print 2012 May.

PMID:
22321830
45.

Comparison of NMR lipid profiles in mitotic arrest and apoptosis as indicators of paclitaxel resistance in cervical cell lines.

Zietkowski D, Payne GS, Nagy E, Mobberley MA, Ryder TA, deSouza NM.

Magn Reson Med. 2012 Aug;68(2):369-77. doi: 10.1002/mrm.23265. Epub 2011 Dec 12.

46.

Combination of steroids and ischial weight-bearing knee ankle foot orthoses in Duchenne's muscular dystrophy prolongs ambulation past 20 years of age--a case report.

Pardo AC, Do T, Ryder T, Meyer A, Miles L, Wong BL.

Neuromuscul Disord. 2011 Nov;21(11):800-2. doi: 10.1016/j.nmd.2011.06.006. Epub 2011 Jul 23.

PMID:
21784636
47.

Understanding testosterone variation in a tropical lek-breeding bird.

Ryder TB, Horton BM, Moore IT.

Biol Lett. 2011 Aug 23;7(4):506-9. doi: 10.1098/rsbl.2010.1219. Epub 2011 Feb 16.

48.

Intrinsic electrophilicity of a 4-substituted-5-cyano-6-(2-methylpyridin-3-yloxy)pyrimidine derivative: structural characterization of glutathione conjugates in vitro.

Kalgutkar AS, Mascitti V, Sharma R, Walker GW, Ryder T, McDonald TS, Chen Y, Preville C, Basak A, McClure KF, Kohrt JT, Robinson RP, Munchhof MJ, Cornelius P.

Chem Res Toxicol. 2011 Feb 18;24(2):269-78. doi: 10.1021/tx100429x. Epub 2011 Feb 3.

PMID:
21288051
49.

LKB1 is required for hepatic bile acid transport and canalicular membrane integrity in mice.

Woods A, Heslegrave AJ, Muckett PJ, Levene AP, Clements M, Mobberley M, Ryder TA, Abu-Hayyeh S, Williamson C, Goldin RD, Ashworth A, Withers DJ, Carling D.

Biochem J. 2011 Feb 15;434(1):49-60. doi: 10.1042/BJ20101721.

50.

Validation of isolated metabolites from drug metabolism studies as analytical standards by quantitative NMR.

Walker GS, Ryder TF, Sharma R, Smith EB, Freund A.

Drug Metab Dispos. 2011 Mar;39(3):433-40. doi: 10.1124/dmd.110.036343. Epub 2010 Nov 22.

PMID:
21098098

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