Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 58

1.

Genetic removal of eIF2α kinase PERK in mice enables hippocampal L-LTP independent of mTORC1 activity.

Zimmermann HR, Yang W, Beckelman BC, Kasica NP, Zhou X, Galli LD, Ryazanov AG, Ma T.

J Neurochem. 2018 Jul;146(2):133-144. doi: 10.1111/jnc.14306.

PMID:
29337352
2.

Epithelial magnesium transport by TRPM6 is essential for prenatal development and adult survival.

Chubanov V, Ferioli S, Wisnowsky A, Simmons DG, Leitzinger C, Einer C, Jonas W, Shymkiv Y, Bartsch H, Braun A, Akdogan B, Mittermeier L, Sytik L, Torben F, Jurinovic V, van der Vorst EP, Weber C, Yildirim ÖA, Sotlar K, Schürmann A, Zierler S, Zischka H, Ryazanov AG, Gudermann T.

Elife. 2016 Dec 19;5. pii: e20914. doi: 10.7554/eLife.20914.

3.

Pharmacological eEF2K activation promotes cell death and inhibits cancer progression.

De Gassart A, Demaria O, Panes R, Zaffalon L, Ryazanov AG, Gilliet M, Martinon F.

EMBO Rep. 2016 Oct;17(10):1471-1484. Epub 2016 Aug 29.

4.

Paradoxical Roles of Elongation Factor-2 Kinase in Stem Cell Survival.

Liao Y, Chu HP, Hu Z, Merkin JJ, Chen J, Liu Z, Degenhardt K, White E, Ryazanov AG.

J Biol Chem. 2016 Sep 9;291(37):19545-57. doi: 10.1074/jbc.M116.724856. Epub 2016 Jul 27.

5.

A Critical Role of TRPM7 As an Ion Channel Protein in Mediating the Mineralization of the Craniofacial Hard Tissues.

Nakano Y, Le MH, Abduweli D, Ho SP, Ryazanova LV, Hu Z, Ryazanov AG, Den Besten PK, Zhang Y.

Front Physiol. 2016 Jul 6;7:258. doi: 10.3389/fphys.2016.00258. eCollection 2016.

6.

eEF2K/eEF2 Pathway Controls the Excitation/Inhibition Balance and Susceptibility to Epileptic Seizures.

Heise C, Taha E, Murru L, Ponzoni L, Cattaneo A, Guarnieri FC, Montani C, Mossa A, Vezzoli E, Ippolito G, Zapata J, Barrera I, Ryazanov AG, Cook J, Poe M, Stephen MR, Kopanitsa M, Benfante R, Rusconi F, Braida D, Francolini M, Proud CG, Valtorta F, Passafaro M, Sala M, Bachi A, Verpelli C, Rosenblum K, Sala C.

Cereb Cortex. 2017 Mar 1;27(3):2226-2248. doi: 10.1093/cercor/bhw075.

7.

Transient Receptor Potential Melastatin 7 Cation Channel Kinase: New Player in Angiotensin II-Induced Hypertension.

Antunes TT, Callera GE, He Y, Yogi A, Ryazanov AG, Ryazanova LV, Zhai A, Stewart DJ, Shrier A, Touyz RM.

Hypertension. 2016 Apr;67(4):763-73. doi: 10.1161/HYPERTENSIONAHA.115.07021. Epub 2016 Feb 29.

8.

TRPM7 kinase activity regulates murine mast cell degranulation.

Zierler S, Sumoza-Toledo A, Suzuki S, Dúill FÓ, Ryazanova LV, Penner R, Ryazanov AG, Fleig A.

J Physiol. 2016 Jun 1;594(11):2957-70. doi: 10.1113/JP271564. Epub 2016 Jan 27.

9.

Elucidating the role of the TRPM7 alpha-kinase: TRPM7 kinase inactivation leads to magnesium deprivation resistance phenotype in mice.

Ryazanova LV, Hu Z, Suzuki S, Chubanov V, Fleig A, Ryazanov AG.

Sci Rep. 2014 Dec 23;4:7599. doi: 10.1038/srep07599.

10.

mTORC1-mediated translational elongation limits intestinal tumour initiation and growth.

Faller WJ, Jackson TJ, Knight JR, Ridgway RA, Jamieson T, Karim SA, Jones C, Radulescu S, Huels DJ, Myant KB, Dudek KM, Casey HA, Scopelliti A, Cordero JB, Vidal M, Pende M, Ryazanov AG, Sonenberg N, Meyuhas O, Hall MN, Bushell M, Willis AE, Sansom OJ.

Nature. 2015 Jan 22;517(7535):497-500. doi: 10.1038/nature13896. Epub 2014 Nov 5.

11.

Identification of a Mg2+-sensitive ORF in the 5'-leader of TRPM7 magnesium channel mRNA.

Nikonorova IA, Kornakov NV, Dmitriev SE, Vassilenko KS, Ryazanov AG.

Nucleic Acids Res. 2014 Nov 10;42(20):12779-88. doi: 10.1093/nar/gku951. Epub 2014 Oct 17.

12.

Germline quality control: eEF2K stands guard to eliminate defective oocytes.

Chu HP, Liao Y, Novak JS, Hu Z, Merkin JJ, Shymkiv Y, Braeckman BP, Dorovkov MV, Nguyen A, Clifford PM, Nagele RG, Harrison DE, Ellis RE, Ryazanov AG.

Dev Cell. 2014 Mar 10;28(5):561-572. doi: 10.1016/j.devcel.2014.01.027. Epub 2014 Feb 27.

13.

Acute suppression of spontaneous neurotransmission drives synaptic potentiation.

Nosyreva E, Szabla K, Autry AE, Ryazanov AG, Monteggia LM, Kavalali ET.

J Neurosci. 2013 Apr 17;33(16):6990-7002. doi: 10.1523/JNEUROSCI.4998-12.2013.

14.

Construction of human activity-based phosphorylation networks.

Newman RH, Hu J, Rho HS, Xie Z, Woodard C, Neiswinger J, Cooper C, Shirley M, Clark HM, Hu S, Hwang W, Jeong JS, Wu G, Lin J, Gao X, Ni Q, Goel R, Xia S, Ji H, Dalby KN, Birnbaum MJ, Cole PA, Knapp S, Ryazanov AG, Zack DJ, Blackshaw S, Pawson T, Gingras AC, Desiderio S, Pandey A, Turk BE, Zhang J, Zhu H, Qian J.

Mol Syst Biol. 2013;9:655. doi: 10.1038/msb.2013.12.

15.

Phosphorylation of eukaryotic elongation factor 2 (eEF2) by cyclin A-cyclin-dependent kinase 2 regulates its inhibition by eEF2 kinase.

Hizli AA, Chi Y, Swanger J, Carter JH, Liao Y, Welcker M, Ryazanov AG, Clurman BE.

Mol Cell Biol. 2013 Feb;33(3):596-604. doi: 10.1128/MCB.01270-12. Epub 2012 Nov 26.

16.

Purification and characterization of tagless recombinant human elongation factor 2 kinase (eEF-2K) expressed in Escherichia coli.

Abramczyk O, Tavares CD, Devkota AK, Ryazanov AG, Turk BE, Riggs AF, Ozpolat B, Dalby KN.

Protein Expr Purif. 2011 Oct;79(2):237-44. doi: 10.1016/j.pep.2011.05.005. Epub 2011 May 14. Erratum in: Protein Expr Purif. 2012 Oct;85(2):250.

17.

Proteomic evaluation and validation of cathepsin D regulated proteins in macrophages exposed to Streptococcus pneumoniae.

Bewley MA, Pham TK, Marriott HM, Noirel J, Chu HP, Ow SY, Ryazanov AG, Read RC, Whyte MK, Chain B, Wright PC, Dockrell DH.

Mol Cell Proteomics. 2011 Jun;10(6):M111.008193. doi: 10.1074/mcp.M111.008193. Epub 2011 Apr 7.

18.

Phosphorylation of annexin A1 by TRPM7 kinase: a switch regulating the induction of an α-helix.

Dorovkov MV, Kostyukova AS, Ryazanov AG.

Biochemistry. 2011 Mar 29;50(12):2187-93. doi: 10.1021/bi101963h. Epub 2011 Feb 18.

19.

The channel-kinase TRPM7 regulates phosphorylation of the translational factor eEF2 via eEF2-k.

Perraud AL, Zhao X, Ryazanov AG, Schmitz C.

Cell Signal. 2011 Mar;23(3):586-93. doi: 10.1016/j.cellsig.2010.11.011. Epub 2010 Nov 25.

20.

TRPM7 is essential for Mg(2+) homeostasis in mammals.

Ryazanova LV, Rondon LJ, Zierler S, Hu Z, Galli J, Yamaguchi TP, Mazur A, Fleig A, Ryazanov AG.

Nat Commun. 2010 Nov 2;1:109.

21.

Resveratrol regulates pathologic angiogenesis by a eukaryotic elongation factor-2 kinase-regulated pathway.

Khan AA, Dace DS, Ryazanov AG, Kelly J, Apte RS.

Am J Pathol. 2010 Jul;177(1):481-92. doi: 10.2353/ajpath.2010.090836. Epub 2010 May 14.

22.

The alpha-kinases TRPM6 and TRPM7, but not eEF-2 kinase, phosphorylate the assembly domain of myosin IIA, IIB and IIC.

Clark K, Middelbeek J, Dorovkov MV, Figdor CG, Ryazanov AG, Lasonder E, van Leeuwen FN.

FEBS Lett. 2008 Sep 3;582(20):2993-7. doi: 10.1016/j.febslet.2008.07.043. Epub 2008 Aug 7.

23.

Elongation factor 2 and fragile X mental retardation protein control the dynamic translation of Arc/Arg3.1 essential for mGluR-LTD.

Park S, Park JM, Kim S, Kim JA, Shepherd JD, Smith-Hicks CL, Chowdhury S, Kaufmann W, Kuhl D, Ryazanov AG, Huganir RL, Linden DJ, Worley PF.

Neuron. 2008 Jul 10;59(1):70-83. doi: 10.1016/j.neuron.2008.05.023.

24.

TRPM7 regulates myosin IIA filament stability and protein localization by heavy chain phosphorylation.

Clark K, Middelbeek J, Lasonder E, Dulyaninova NG, Morrice NA, Ryazanov AG, Bresnick AR, Figdor CG, van Leeuwen FN.

J Mol Biol. 2008 May 9;378(4):790-803. doi: 10.1016/j.jmb.2008.02.057. Epub 2008 Mar 4.

25.

A pharmacoproteomic approach implicates eukaryotic elongation factor 2 kinase in ER stress-induced cell death.

Boyce M, Py BF, Ryazanov AG, Minden JS, Long K, Ma D, Yuan J.

Cell Death Differ. 2008 Mar;15(3):589-99. doi: 10.1038/sj.cdd.4402296. Epub 2008 Jan 11.

26.

Autophagy regulates ageing in C. elegans.

Hars ES, Qi H, Ryazanov AG, Jin S, Cai L, Hu C, Liu LF.

Autophagy. 2007 Mar-Apr;3(2):93-5. Epub 2007 Mar 30.

PMID:
17204841
27.

TRPM7, a novel regulator of actomyosin contractility and cell adhesion.

Clark K, Langeslag M, van Leeuwen B, Ran L, Ryazanov AG, Figdor CG, Moolenaar WH, Jalink K, van Leeuwen FN.

EMBO J. 2006 Jan 25;25(2):290-301. Epub 2006 Jan 12.

28.

The channel kinases TRPM6 and TRPM7 are functionally nonredundant.

Schmitz C, Dorovkov MV, Zhao X, Davenport BJ, Ryazanov AG, Perraud AL.

J Biol Chem. 2005 Nov 11;280(45):37763-71. Epub 2005 Sep 2.

29.

A TRPM7 variant shows altered sensitivity to magnesium that may contribute to the pathogenesis of two Guamanian neurodegenerative disorders.

Hermosura MC, Nayakanti H, Dorovkov MV, Calderon FR, Ryazanov AG, Haymer DS, Garruto RM.

Proc Natl Acad Sci U S A. 2005 Aug 9;102(32):11510-5. Epub 2005 Jul 28.

30.

Alpha-kinase 1, a new component in apical protein transport.

Heine M, Cramm-Behrens CI, Ansari A, Chu HP, Ryazanov AG, Naim HY, Jacob R.

J Biol Chem. 2005 Jul 8;280(27):25637-43. Epub 2005 May 9.

31.

Phosphorylation of annexin I by TRPM7 channel-kinase.

Dorovkov MV, Ryazanov AG.

J Biol Chem. 2004 Dec 3;279(49):50643-6. Epub 2004 Oct 12.

32.

Alpha-kinases: analysis of the family and comparison with conventional protein kinases.

Drennan D, Ryazanov AG.

Prog Biophys Mol Biol. 2004 May;85(1):1-32. Review.

PMID:
15050379
33.

Characterization of the protein kinase activity of TRPM7/ChaK1, a protein kinase fused to the transient receptor potential ion channel.

Ryazanova LV, Dorovkov MV, Ansari A, Ryazanov AG.

J Biol Chem. 2004 Jan 30;279(5):3708-16. Epub 2003 Oct 30.

34.

Regulation of elongation factor-2 kinase by pH.

Dorovkov MV, Pavur KS, Petrov AN, Ryazanov AG.

Biochemistry. 2002 Nov 12;41(45):13444-50.

PMID:
12416990
35.

Elongation factor-2 kinase and its newly discovered relatives.

Ryazanov AG.

FEBS Lett. 2002 Mar 6;514(1):26-9. Review.

36.

Protein turnover plays a key role in aging.

Ryazanov AG, Nefsky BS.

Mech Ageing Dev. 2002 Jan;123(2-3):207-13. Review.

PMID:
11718813
37.

Mapping the functional domains of elongation factor-2 kinase.

Pavur KS, Petrov AN, Ryazanov AG.

Biochemistry. 2000 Oct 10;39(40):12216-24.

PMID:
11015200
38.

Does prothymosin alpha affect the phosphorylation of elongation factor 2?

Enkemann SA, Pavur KS, Ryazanov AG, Berger SL.

J Biol Chem. 1999 Jun 25;274(26):18644-50.

39.

Alpha-kinases: a new class of protein kinases with a novel catalytic domain.

Ryazanov AG, Pavur KS, Dorovkov MV.

Curr Biol. 1999 Jan 28;9(2):R43-5. No abstract available.

40.

An examination of the role of increased cytosolic free Ca2+ concentrations in the inhibition of mRNA translation.

Laitusis AL, Brostrom CO, Ryazanov AG, Brostrom MA.

Arch Biochem Biophys. 1998 Jun 15;354(2):270-80.

PMID:
9637736
41.

Identification of a new class of protein kinases represented by eukaryotic elongation factor-2 kinase.

Ryazanov AG, Ward MD, Mendola CE, Pavur KS, Dorovkov MV, Wiedmann M, Erdjument-Bromage H, Tempst P, Parmer TG, Prostko CR, Germino FJ, Hait WN.

Proc Natl Acad Sci U S A. 1997 May 13;94(10):4884-9.

42.

Elongation factor-2 kinase: immunological evidence for the existence of tissue-specific isoforms.

Hait WN, Ward MD, Trakht IN, Ryazanov AG.

FEBS Lett. 1996 Nov 11;397(1):55-60.

43.

Transient inhibition of protein synthesis induces expression of proto-oncogenes and stimulates resting cells to enter the cell cycle.

Rosenwald IB, Setkov NA, Kazakov VN, Chen JJ, Ryazanov AG, London IM, Epifanova OI.

Cell Prolif. 1995 Dec;28(12):631-44.

PMID:
8634371
44.
45.
46.

Phosphorylation of elongation factor 2: a key mechanism regulating gene expression in vertebrates.

Ryazanov AG, Spirin AS.

New Biol. 1990 Oct;2(10):843-50. Review.

PMID:
1964087
50.

Organization of soluble enzymes in the cell. Relay at the surface.

Ryazanov AG.

FEBS Lett. 1988 Sep 12;237(1-2):1-3.

Supplemental Content

Loading ...
Support Center