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Items: 1 to 50 of 145

1.

Phosphotungstic acid-enhanced microCT: Optimized protocols for embryonic and early postnatal mice.

Lesciotto KM, Motch Perrine SM, Kawasaki M, Stecko T, Ryan TM, Kawasaki K, Richtsmeier JT.

Dev Dyn. 2019 Nov 18. doi: 10.1002/dvdy.136. [Epub ahead of print]

PMID:
31736206
2.

Baby steps towards linking calcaneal trabecular bone ontogeny and the development of bipedal human gait.

Saers JPP, Ryan TM, Stock JT.

J Anat. 2019 Nov 14. doi: 10.1111/joa.13120. [Epub ahead of print]

PMID:
31725189
3.

Solution structure of linear battacin lipopeptides - the effect of lengthening fatty acid chain.

Kihara S, De Zoysa GH, Shahlori R, Vadakkedath PG, Ryan TM, Mata JP, Sarojini V, McGillivray DJ.

Soft Matter. 2019 Sep 25;15(37):7501-7508. doi: 10.1039/c9sm00932a.

PMID:
31528955
4.

Trabecular bone structure scales allometrically in the foot of four human groups.

Saers JPP, Ryan TM, Stock JT.

J Hum Evol. 2019 Oct;135:102654. doi: 10.1016/j.jhevol.2019.102654. Epub 2019 Aug 26.

PMID:
31465989
5.

Changes in the orientations of cellulose microfibrils during the development of collenchyma cell walls of celery (Apium graveolens L.).

Chen D, Melton LD, McGillivray DJ, Ryan TM, Harris PJ.

Planta. 2019 Dec;250(6):1819-1832. doi: 10.1007/s00425-019-03262-8. Epub 2019 Aug 28.

PMID:
31463558
6.

A 3.8-million-year-old hominin cranium from Woranso-Mille, Ethiopia.

Haile-Selassie Y, Melillo SM, Vazzana A, Benazzi S, Ryan TM.

Nature. 2019 Sep;573(7773):214-219. doi: 10.1038/s41586-019-1513-8. Epub 2019 Aug 28.

PMID:
31462770
7.

In Utero Gene Therapy (IUGT) Using GLOBE Lentiviral Vector Phenotypically Corrects the Heterozygous Humanised Mouse Model and Its Progress Can Be Monitored Using MRI Techniques.

Shangaris P, Loukogeorgakis SP, Subramaniam S, Flouri C, Jackson LH, Wang W, Blundell MP, Liu S, Eaton S, Bakhamis N, Ramachandra DL, Maghsoudlou P, Urbani L, Waddington SN, Eddaoudi A, Archer J, Antoniou MN, Stuckey DJ, Schmidt M, Thrasher AJ, Ryan TM, Coppi P, David AL.

Sci Rep. 2019 Aug 12;9(1):11592. doi: 10.1038/s41598-019-48078-4.

8.

Comparative description and taxonomy of new hominin juvenile mandibles from the Pliocene of Woranso-Mille (Central Afar, Ethiopia).

Haile-Selassie Y, Ryan TM.

J Hum Evol. 2019 Jul;132:15-31. doi: 10.1016/j.jhevol.2019.04.005. Epub 2019 May 3.

PMID:
31203845
9.

Anatomical basis and physiological role of cerebrospinal fluid transport through the murine cribriform plate.

Norwood JN, Zhang Q, Card D, Craine A, Ryan TM, Drew PJ.

Elife. 2019 May 7;8. pii: e44278. doi: 10.7554/eLife.44278.

10.

Resolving solution conformations of the model semi-flexible polyelectrolyte homogalacturonan using molecular dynamics simulations and small-angle x-ray scattering.

Mansel BW, Irani AH, Ryan TM, McGillivray DJ, Chen HL, Williams MAK.

Eur Phys J E Soft Matter. 2019 Feb 21;42(2):19. doi: 10.1140/epje/i2019-11776-0.

PMID:
30788674
11.

Trabecular Bone Structure in the Distal Femur of Humans, Apes, and Baboons.

Sukhdeo S, Parsons J, Niu XM, Ryan TM.

Anat Rec (Hoboken). 2018 Dec 12. doi: 10.1002/ar.24050. [Epub ahead of print]

PMID:
30548834
12.

Complex variation of trabecular bone structure in the proximal humerus and femur of five modern human populations.

Doershuk LJ, Saers JPP, Shaw CN, Jashashvili T, Carlson KJ, Stock JT, Ryan TM.

Am J Phys Anthropol. 2019 Jan;168(1):104-118. doi: 10.1002/ajpa.23725.

PMID:
30515772
13.

Trabecular bone functional adaptation and sexual dimorphism in the human foot.

Saers JPP, Ryan TM, Stock JT.

Am J Phys Anthropol. 2019 Jan;168(1):154-169. doi: 10.1002/ajpa.23732. Epub 2018 Nov 21.

PMID:
30462351
14.

Structural and functional characterisation of the entry point to pyocyanin biosynthesis in Pseudomonas aeruginosa defines a new 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase subclass.

Sterritt OW, Lang EJM, Kessans SA, Ryan TM, Demeler B, Jameson GB, Parker EJ.

Biosci Rep. 2018 Oct 17;38(5). pii: BSR20181605. doi: 10.1042/BSR20181605. Print 2018 Oct 31.

15.

Human-like hip joint loading in Australopithecus africanus and Paranthropus robustus.

Ryan TM, Carlson KJ, Gordon AD, Jablonski N, Shaw CN, Stock JT.

J Hum Evol. 2018 Aug;121:12-24. doi: 10.1016/j.jhevol.2018.03.008. Epub 2018 Apr 27.

PMID:
29706230
16.

Grouper iridovirus GIV66 is a Bcl-2 protein that inhibits apoptosis by exclusively sequestering Bim.

Banjara S, Mao J, Ryan TM, Caria S, Kvansakul M.

J Biol Chem. 2018 Apr 13;293(15):5464-5477. doi: 10.1074/jbc.RA117.000591. Epub 2018 Feb 26.

17.

Allogeneic bone marrow transplant in the absence of cytoreductive conditioning rescues mice with β-thalassemia major.

Huo Y, Lockhart JR, Liu S, Fontenard S, Berlett M, Ryan TM.

Blood Adv. 2017 Nov 28;1(25):2421-2432. doi: 10.1182/bloodadvances.2017009449. eCollection 2017 Nov 28.

18.

Asymmetry in the Cortical and Trabecular Bone of the Human Humerus During Development.

Perchalski B, Placke A, Sukhdeo SM, Shaw CN, Gosman JH, Raichlen DA, Ryan TM.

Anat Rec (Hoboken). 2018 Jun;301(6):1012-1025. doi: 10.1002/ar.23705. Epub 2018 Feb 1.

19.

2017 publication guidelines for structural modelling of small-angle scattering data from biomolecules in solution: an update.

Trewhella J, Duff AP, Durand D, Gabel F, Guss JM, Hendrickson WA, Hura GL, Jacques DA, Kirby NM, Kwan AH, Pérez J, Pollack L, Ryan TM, Sali A, Schneidman-Duhovny D, Schwede T, Svergun DI, Sugiyama M, Tainer JA, Vachette P, Westbrook J, Whitten AE.

Acta Crystallogr D Struct Biol. 2017 Sep 1;73(Pt 9):710-728. doi: 10.1107/S2059798317011597. Epub 2017 Aug 18.

20.

Integration of Brain and Skull in Prenatal Mouse Models of Apert and Crouzon Syndromes.

Motch Perrine SM, Stecko T, Neuberger T, Jabs EW, Ryan TM, Richtsmeier JT.

Front Hum Neurosci. 2017 Jul 25;11:369. doi: 10.3389/fnhum.2017.00369. eCollection 2017.

21.

Evolution of the hominin knee and ankle.

Frelat MA, Shaw CN, Sukhdeo S, Hublin JJ, Benazzi S, Ryan TM.

J Hum Evol. 2017 Jul;108:147-160. doi: 10.1016/j.jhevol.2017.03.006. Epub 2017 May 22.

PMID:
28622927
22.

Biochemically-defined pools of amyloid-β in sporadic Alzheimer's disease: correlation with amyloid PET.

Roberts BR, Lind M, Wagen AZ, Rembach A, Frugier T, Li QX, Ryan TM, McLean CA, Doecke JD, Rowe CC, Villemagne VL, Masters CL.

Brain. 2017 May 1;140(5):1486-1498. doi: 10.1093/brain/awx057.

PMID:
28383676
23.

Sugar-coated proteins: the importance of degree of polymerisation of oligo-galacturonic acid on protein binding and aggregation.

Xu AY, Melton LD, Ryan TM, Mata JP, Jameson GB, Rekas A, Williams MA, McGillivray DJ.

Soft Matter. 2017 Apr 5;13(14):2698-2707. doi: 10.1039/c6sm02660e.

PMID:
28337496
24.

Non-invasive MRI biomarkers for the early assessment of iron overload in a humanized mouse model of β-thalassemia.

Jackson LH, Vlachodimitropoulou E, Shangaris P, Roberts TA, Ryan TM, Campbell-Washburn AE, David AL, Porter JB, Lythgoe MF, Stuckey DJ.

Sci Rep. 2017 Feb 27;7:43439. doi: 10.1038/srep43439.

25.

Improved radiation dose efficiency in solution SAXS using a sheath flow sample environment.

Kirby N, Cowieson N, Hawley AM, Mudie ST, McGillivray DJ, Kusel M, Samardzic-Boban V, Ryan TM.

Acta Crystallogr D Struct Biol. 2016 Dec 1;72(Pt 12):1254-1266. Epub 2016 Nov 29.

26.

Corrigendum to "Dentognathic remains of Australopithecus afarensis from Nefuraytu (Woranso-Mille, Ethiopia): Comparative description, geology, and paleoecological context" [J Hum Evol 100 (2016) 35-53].

Haile-Selassie Y, Melillo SM, Ryan TM, Levin NE, Saylor BZ, Deino A, Mundil R, Scott G, Alene M, Gibert L.

J Hum Evol. 2017 Jan;102:81. doi: 10.1016/j.jhevol.2016.11.001. Epub 2016 Nov 23. No abstract available.

PMID:
27887742
27.

Dentognathic remains of Australopithecus afarensis from Nefuraytu (Woranso-Mille, Ethiopia): Comparative description, geology, and paleoecological context.

Haile-Selassie Y, Melillo SM, Ryan TM, Levin NE, Saylor BZ, Deino A, Mundil R, Scott G, Mulugeta Alene, Gibert L.

J Hum Evol. 2016 Nov;100:35-53. doi: 10.1016/j.jhevol.2016.08.003. Erratum in: J Hum Evol. 2017 Jan;102:81.

PMID:
27765148
28.

Redescription of Pseudotropheus livingstonii and Pseudotropheus elegans from Lake Malaŵi, Africa.

Stauffer JR, Konings AF, Ryan TM.

Zootaxa. 2016 Aug 19;4154(2):169-78. doi: 10.11646/zootaxa.4154.2.4.

PMID:
27615832
29.

Trabecular bone structural variation throughout the human lower limb.

Saers JP, Cazorla-Bak Y, Shaw CN, Stock JT, Ryan TM.

J Hum Evol. 2016 Aug;97:97-108. doi: 10.1016/j.jhevol.2016.05.012. Epub 2016 Jul 13.

PMID:
27457548
30.

Combined pressure and temperature denaturation of ribonuclease A produces alternate denatured states.

Ryan TM, Xun Y, Cowieson NP, Mata JP, Jackson A, Pauw BR, Smith AJ, Kirby N, McGillivray D.

Biochem Biophys Res Commun. 2016 May 13;473(4):834-839. doi: 10.1016/j.bbrc.2016.03.135. Epub 2016 Mar 29.

PMID:
27037018
31.

Apolipoprotein C-II Adopts Distinct Structures in Complex with Micellar and Submicellar Forms of the Amyloid-Inhibiting Lipid-Mimetic Dodecylphosphocholine.

Ryan TM, Griffin MD, McGillivray DJ, Knott RB, Wood K, Masters CL, Kirby N, Curtain CC.

Biophys J. 2016 Jan 5;110(1):85-94. doi: 10.1016/j.bpj.2015.11.007.

32.

The histone H2A deubiquitinase Usp16 regulates hematopoiesis and hematopoietic stem cell function.

Gu Y, Jones AE, Yang W, Liu S, Dai Q, Liu Y, Swindle CS, Zhou D, Zhang Z, Ryan TM, Townes TM, Klug CA, Chen D, Wang H.

Proc Natl Acad Sci U S A. 2016 Jan 5;113(1):E51-60. doi: 10.1073/pnas.1517041113. Epub 2015 Dec 22.

33.

Gourds and squashes (Cucurbita spp.) adapted to megafaunal extinction and ecological anachronism through domestication.

Kistler L, Newsom LA, Ryan TM, Clarke AC, Smith BD, Perry GH.

Proc Natl Acad Sci U S A. 2015 Dec 8;112(49):15107-12. doi: 10.1073/pnas.1516109112. Epub 2015 Nov 16.

34.

The Role of Lipid in Misfolding and Amyloid Fibril Formation by Apolipoprotein C-II.

Ryan TM, Mok YF, Howlett GJ, Griffin MD.

Adv Exp Med Biol. 2015;855:157-74. doi: 10.1007/978-3-319-17344-3_7. Review.

PMID:
26149930
35.

Fluphenazine·HCl and Epigallocatechin Gallate Modulate the Rate of Formation and Structural Properties of Apolipoprotein C-II Amyloid Fibrils.

Zlatic CO, Mao Y, Ryan TM, Mok YF, Roberts BR, Howlett GJ, Griffin MD.

Biochemistry. 2015 Jun 23;54(24):3831-8. doi: 10.1021/acs.biochem.5b00399. Epub 2015 Jun 12.

PMID:
26021642
36.

New species from Ethiopia further expands Middle Pliocene hominin diversity.

Haile-Selassie Y, Gibert L, Melillo SM, Ryan TM, Alene M, Deino A, Levin NE, Scott G, Saylor BZ.

Nature. 2015 May 28;521(7553):483-8. doi: 10.1038/nature14448.

PMID:
26017448
37.

The prion protein regulates beta-amyloid-mediated self-renewal of neural stem cells in vitro.

Collins SJ, Tumpach C, Li QX, Lewis V, Ryan TM, Roberts B, Drew SC, Lawson VA, Haigh CL.

Stem Cell Res Ther. 2015 Apr 11;6:60. doi: 10.1186/s13287-015-0067-4.

38.

An ontogenetic framework linking locomotion and trabecular bone architecture with applications for reconstructing hominin life history.

Raichlen DA, Gordon AD, Foster AD, Webber JT, Sukhdeo SM, Scott RS, Gosman JH, Ryan TM.

J Hum Evol. 2015 Apr;81:1-12. doi: 10.1016/j.jhevol.2015.01.003. Epub 2015 Mar 3.

PMID:
25743432
39.

Stabilization of nontoxic Aβ-oligomers: insights into the mechanism of action of hydroxyquinolines in Alzheimer's disease.

Ryan TM, Roberts BR, McColl G, Hare DJ, Doble PA, Li QX, Lind M, Roberts AM, Mertens HD, Kirby N, Pham CL, Hinds MG, Adlard PA, Barnham KJ, Curtain CC, Masters CL.

J Neurosci. 2015 Feb 18;35(7):2871-84. doi: 10.1523/JNEUROSCI.2912-14.2015.

40.

Small angle X-ray scattering analysis of Cu(2+)-induced oligomers of the Alzheimer's amyloid β peptide.

Ryan TM, Kirby N, Mertens HD, Roberts B, Barnham KJ, Cappai R, Pham Cle L, Masters CL, Curtain CC.

Metallomics. 2015 Mar;7(3):536-43. doi: 10.1039/c4mt00323c.

PMID:
25687761
41.

Bayesian graphical network analyses reveal complex biological interactions specific to Alzheimer's disease.

Rembach A, Stingo FC, Peterson C, Vannucci M, Do KA, Wilson WJ, Macaulay SL, Ryan TM, Martins RN, Ames D, Masters CL, Doecke JD; AIBL Research Group.

J Alzheimers Dis. 2015;44(3):917-25. doi: 10.3233/JAD-141497.

42.

Gracility of the modern Homo sapiens skeleton is the result of decreased biomechanical loading.

Ryan TM, Shaw CN.

Proc Natl Acad Sci U S A. 2015 Jan 13;112(2):372-7. doi: 10.1073/pnas.1418646112. Epub 2014 Dec 22.

43.

Neuroprotective peptide-macrocycle conjugates reveal complex structure-activity relationships in their interactions with amyloid β.

Yu M, Ryan TM, Ellis S, Bush AI, Triccas JA, Rutledge PJ, Todd MH.

Metallomics. 2014 Oct;6(10):1931-40. doi: 10.1039/c4mt00122b. Epub 2014 Aug 18.

PMID:
25132118
44.

Screening for dementia and other causes of cognitive impairment in general hospital in-patients.

Shenkin SD, Russ TC, Ryan TM, MacLullich AM.

Age Ageing. 2014 Mar;43(2):166-8. doi: 10.1093/ageing/aft184. Epub 2013 Nov 25. No abstract available.

PMID:
24280009
45.

Profiling the iron, copper and zinc content in primary neuron and astrocyte cultures by rapid online quantitative size exclusion chromatography-inductively coupled plasma-mass spectrometry.

Hare DJ, Grubman A, Ryan TM, Lothian A, Liddell JR, Grimm R, Matsuda T, Doble PA, Cherny RA, Bush AI, White AR, Masters CL, Roberts BR.

Metallomics. 2013 Dec;5(12):1656-62. doi: 10.1039/c3mt00227f. Epub 2013 Oct 17.

PMID:
24132241
46.

Progress towards a consensus on biomarkers for Alzheimer's disease: a review of peripheral analytes.

Rembach A, Ryan TM, Roberts BR, Doecke JD, Wilson WJ, Watt AD, Barnham KJ, Masters CL.

Biomark Med. 2013 Aug;7(4):641-62. doi: 10.2217/bmm.13.59. Review.

PMID:
23905901
47.

Metalloproteomics: principles, challenges and applications to neurodegeneration.

Lothian A, Hare DJ, Grimm R, Ryan TM, Masters CL, Roberts BR.

Front Aging Neurosci. 2013 Jul 18;5:35. doi: 10.3389/fnagi.2013.00035. eCollection 2013.

48.

Ammonium hydroxide treatment of Aβ produces an aggregate free solution suitable for biophysical and cell culture characterization.

Ryan TM, Caine J, Mertens HD, Kirby N, Nigro J, Breheney K, Waddington LJ, Streltsov VA, Curtain C, Masters CL, Roberts BR.

PeerJ. 2013 May 7;1:e73. doi: 10.7717/peerj.73. Print 2013.

49.

Development of cortical bone geometry in the human femoral and tibial diaphysis.

Gosman JH, Hubbell ZR, Shaw CN, Ryan TM.

Anat Rec (Hoboken). 2013 May;296(5):774-87. doi: 10.1002/ar.22688. Epub 2013 Mar 27.

50.

Erythropoiesis in the absence of adult hemoglobin.

Liu S, McConnell SC, Ryan TM.

Mol Cell Biol. 2013 Jun;33(11):2241-51. doi: 10.1128/MCB.01734-12. Epub 2013 Mar 25.

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