Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 180

1.

Bi-allelic Mutations in NDUFA6 Establish Its Role in Early-Onset Isolated Mitochondrial Complex I Deficiency.

Alston CL, Heidler J, Dibley MG, Kremer LS, Taylor LS, Fratter C, French CE, Glasgow RIC, Feichtinger RG, Delon I, Pagnamenta AT, Dolling H, Lemonde H, Aiton N, Bjørnstad A, Henneke L, Gärtner J, Thiele H, Tauchmannova K, Quaghebeur G, Houstek J, Sperl W, Raymond FL, Prokisch H, Mayr JA, McFarland R, Poulton J, Ryan MT, Wittig I, Henneke M, Taylor RW.

Am J Hum Genet. 2018 Oct 4;103(4):592-601. doi: 10.1016/j.ajhg.2018.08.013. Epub 2018 Sep 20.

2.

OXA1L mutations cause mitochondrial encephalopathy and a combined oxidative phosphorylation defect.

Thompson K, Mai N, Oláhová M, Scialó F, Formosa LE, Stroud DA, Garrett M, Lax NZ, Robertson FM, Jou C, Nascimento A, Ortez C, Jimenez-Mallebrera C, Hardy SA, He L, Brown GK, Marttinen P, McFarland R, Sanz A, Battersby BJ, Bonnen PE, Ryan MT, Chrzanowska-Lightowlers ZM, Lightowlers RN, Taylor RW.

EMBO Mol Med. 2018 Sep 10. pii: e9060. doi: 10.15252/emmm.201809060. [Epub ahead of print]

3.

Mitochondrial OXPHOS complex assembly lines.

Formosa LE, Ryan MT.

Nat Cell Biol. 2018 May;20(5):511-513. doi: 10.1038/s41556-018-0098-z. No abstract available.

PMID:
29662174
4.

Mitochondrial fission protein Drp1 inhibition promotes cardiac mesodermal differentiation of human pluripotent stem cells.

Hoque A, Sivakumaran P, Bond ST, Ling NXY, Kong AM, Scott JW, Bandara N, Hernández D, Liu GS, Wong RCB, Ryan MT, Hausenloy DJ, Kemp BE, Oakhill JS, Drew BG, Pébay A, Lim SY.

Cell Death Discov. 2018 Mar 5;4:39. doi: 10.1038/s41420-018-0042-9. eCollection 2018 Dec.

5.

BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis.

McArthur K, Whitehead LW, Heddleston JM, Li L, Padman BS, Oorschot V, Geoghegan ND, Chappaz S, Davidson S, San Chin H, Lane RM, Dramicanin M, Saunders TL, Sugiana C, Lessene R, Osellame LD, Chew TL, Dewson G, Lazarou M, Ramm G, Lessene G, Ryan MT, Rogers KL, van Delft MF, Kile BT.

Science. 2018 Feb 23;359(6378). pii: eaao6047. doi: 10.1126/science.aao6047.

PMID:
29472455
6.

Loss of BIM increases mitochondrial oxygen consumption and lipid oxidation, reduces adiposity and improves insulin sensitivity in mice.

Wali JA, Galic S, Tan CY, Gurzov EN, Frazier AE, Connor T, Ge J, Pappas EG, Stroud D, Varanasi LC, Selck C, Ryan MT, Thorburn DR, Kemp BE, Krishnamurthy B, Kay TW, McGee SL, Thomas HE.

Cell Death Differ. 2018 Jan;25(1):217-225. doi: 10.1038/cdd.2017.168. Epub 2017 Oct 20.

PMID:
29053141
7.

Mitochondria - The energy powerhouses.

Ryan MT.

Semin Cell Dev Biol. 2018 Apr;76:130-131. doi: 10.1016/j.semcdb.2017.09.038. Epub 2017 Oct 5. No abstract available.

PMID:
28969982
8.

Identification of new channels by systematic analysis of the mitochondrial outer membrane.

Krüger V, Becker T, Becker L, Montilla-Martinez M, Ellenrieder L, Vögtle FN, Meyer HE, Ryan MT, Wiedemann N, Warscheid B, Pfanner N, Wagner R, Meisinger C.

J Cell Biol. 2017 Nov 6;216(11):3485-3495. doi: 10.1083/jcb.201706043. Epub 2017 Sep 15.

9.

The constriction and scission machineries involved in mitochondrial fission.

Kraus F, Ryan MT.

J Cell Sci. 2017 Sep 15;130(18):2953-2960. doi: 10.1242/jcs.199562. Epub 2017 Aug 25. Review.

10.

Building a complex complex: Assembly of mitochondrial respiratory chain complex I.

Formosa LE, Dibley MG, Stroud DA, Ryan MT.

Semin Cell Dev Biol. 2018 Apr;76:154-162. doi: 10.1016/j.semcdb.2017.08.011. Epub 2017 Aug 7. Review.

PMID:
28797839
11.

The Importance of Self-Efficacy in Parental Emergency Preparedness: A Moderated Mediation Model.

Ryan MT, Rohrbeck CA, Wirtz PW.

Disaster Med Public Health Prep. 2018 Jun;12(3):345-351. doi: 10.1017/dmp.2017.80. Epub 2017 Aug 1.

PMID:
28760169
12.

Sengers Syndrome-Associated Mitochondrial Acylglycerol Kinase Is a Subunit of the Human TIM22 Protein Import Complex.

Kang Y, Stroud DA, Baker MJ, De Souza DP, Frazier AE, Liem M, Tull D, Mathivanan S, McConville MJ, Thorburn DR, Ryan MT, Stojanovski D.

Mol Cell. 2017 Aug 3;67(3):457-470.e5. doi: 10.1016/j.molcel.2017.06.014. Epub 2017 Jul 14.

13.

Hail and Farewell.

Ryan MT.

Health Phys. 2017 Jul;113(1):1. doi: 10.1097/HP.0000000000000701. No abstract available.

PMID:
28542005
14.

An investigation into the effects of maternal supplementation with excess iodine on the mechanisms and impacts of reduced IgG absorption in the lamb postpartum.

McGovern FM, Sweeney T, Ryan MT, Lott S, Campion FP, Boland TM.

Br J Nutr. 2017 Apr;117(7):951-963. doi: 10.1017/S0007114517000575. Epub 2017 Apr 26.

PMID:
28443527
15.

Preservation of skeletal muscle mitochondrial content in older adults: relationship between mitochondria, fibre type and high-intensity exercise training.

Wyckelsma VL, Levinger I, McKenna MJ, Formosa LE, Ryan MT, Petersen AC, Anderson MJ, Murphy RM.

J Physiol. 2017 Jun 1;595(11):3345-3359. doi: 10.1113/JP273950. Epub 2017 Apr 23.

16.

TRANSITION.

Ryan MT, Little CA.

Health Phys. 2017 Apr;112(4):325. doi: 10.1097/HP.0000000000000660. No abstract available.

PMID:
28234690
17.

Introduction of the 40th Lauriston S. Taylor Lecturer: John W. Poston, Sr.

Ryan MT.

Health Phys. 2017 Feb;112(2):191-192. doi: 10.1097/HP.0000000000000627. No abstract available.

PMID:
28027160
18.

A novel isoform of the human mitochondrial complex I subunit NDUFV3.

Dibley MG, Ryan MT, Stroud DA.

FEBS Lett. 2017 Jan;591(1):109-117. doi: 10.1002/1873-3468.12527. Epub 2016 Dec 30.

19.

Mitochondrial fusion: Reaching the end of mitofusin's tether.

Formosa LE, Ryan MT.

J Cell Biol. 2016 Dec 5;215(5):597-598. Epub 2016 Nov 23.

20.

The application of transcriptomic data in the authentication of beef derived from contrasting production systems.

Sweeney T, Lejeune A, Moloney AP, Monahan FJ, Gettigan PM, Downey G, Park SD, Ryan MT.

BMC Genomics. 2016 Sep 21;17(1):746.

21.

Accessory subunits are integral for assembly and function of human mitochondrial complex I.

Stroud DA, Surgenor EE, Formosa LE, Reljic B, Frazier AE, Dibley MG, Osellame LD, Stait T, Beilharz TH, Thorburn DR, Salim A, Ryan MT.

Nature. 2016 Oct 6;538(7623):123-126. doi: 10.1038/nature19754. Epub 2016 Sep 14.

PMID:
27626371
22.

Immunogenomics of gastrointestinal nematode infection in ruminants - breeding for resistance to produce food sustainably and safely.

Sweeney T, Hanrahan JP, Ryan MT, Good B.

Parasite Immunol. 2016 Sep;38(9):569-86. doi: 10.1111/pim.12347. Review.

23.

Biallelic Mutations in TMEM126B Cause Severe Complex I Deficiency with a Variable Clinical Phenotype.

Alston CL, Compton AG, Formosa LE, Strecker V, Oláhová M, Haack TB, Smet J, Stouffs K, Diakumis P, Ciara E, Cassiman D, Romain N, Yarham JW, He L, De Paepe B, Vanlander AV, Seneca S, Feichtinger RG, Płoski R, Rokicki D, Pronicka E, Haller RG, Van Hove JL, Bahlo M, Mayr JA, Van Coster R, Prokisch H, Wittig I, Ryan MT, Thorburn DR, Taylor RW.

Am J Hum Genet. 2016 Jul 7;99(1):217-27. doi: 10.1016/j.ajhg.2016.05.021. Epub 2016 Jun 30.

24.

A Syntenic Cross Species Aneuploidy Genetic Screen Links RCAN1 Expression to β-Cell Mitochondrial Dysfunction in Type 2 Diabetes.

Peiris H, Duffield MD, Fadista J, Jessup CF, Kashmir V, Genders AJ, McGee SL, Martin AM, Saiedi M, Morton N, Carter R, Cousin MA, Kokotos AC, Oskolkov N, Volkov P, Hough TA, Fisher EM, Tybulewicz VL, Busciglio J, Coskun PE, Becker A, Belichenko PV, Mobley WC, Ryan MT, Chan JY, Laybutt DR, Coates PT, Yang S, Ling C, Groop L, Pritchard MA, Keating DJ.

PLoS Genet. 2016 May 19;12(5):e1006033. doi: 10.1371/journal.pgen.1006033. eCollection 2016 May.

25.

Cooperative and independent roles of the Drp1 adaptors Mff, MiD49 and MiD51 in mitochondrial fission.

Osellame LD, Singh AP, Stroud DA, Palmer CS, Stojanovski D, Ramachandran R, Ryan MT.

J Cell Sci. 2016 Jun 1;129(11):2170-81. doi: 10.1242/jcs.185165. Epub 2016 Apr 12.

26.

Deficiency in Apoptosis-Inducing Factor Recapitulates Chronic Kidney Disease via Aberrant Mitochondrial Homeostasis.

Coughlan MT, Higgins GC, Nguyen TV, Penfold SA, Thallas-Bonke V, Tan SM, Ramm G, Van Bergen NJ, Henstridge DC, Sourris KC, Harcourt BE, Trounce IA, Robb PM, Laskowski A, McGee SL, Genders AJ, Walder K, Drew BG, Gregorevic P, Qian H, Thomas MC, Jerums G, Macisaac RJ, Skene A, Power DA, Ekinci EI, Wijeyeratne XW, Gallo LA, Herman-Edelstein M, Ryan MT, Cooper ME, Thorburn DR, Forbes JM.

Diabetes. 2016 Apr;65(4):1085-98. doi: 10.2337/db15-0864. Epub 2016 Jan 28.

27.

Polymorphisms in the regulatory region of the porcine MYLPF gene are related to meat quality traits in the Large White breed.

Ryan MT, O'Halloran AM, Hamill RM, Davey GC, Gil M, Southwood OI, Sweeney T.

Meat Sci. 2016 Mar;113:104-6. doi: 10.1016/j.meatsci.2015.11.016. Epub 2015 Nov 28.

PMID:
26638021
28.

Translation and Assembly of Radiolabeled Mitochondrial DNA-Encoded Protein Subunits from Cultured Cells and Isolated Mitochondria.

Formosa LE, Hofer A, Tischner C, Wenz T, Ryan MT.

Methods Mol Biol. 2016;1351:115-29. doi: 10.1007/978-1-4939-3040-1_9.

PMID:
26530678
29.

COA6 is a mitochondrial complex IV assembly factor critical for biogenesis of mtDNA-encoded COX2.

Stroud DA, Maher MJ, Lindau C, Vögtle FN, Frazier AE, Surgenor E, Mountford H, Singh AP, Bonas M, Oeljeklaus S, Warscheid B, Meisinger C, Thorburn DR, Ryan MT.

Hum Mol Genet. 2015 Oct 1;24(19):5404-15. doi: 10.1093/hmg/ddv265. Epub 2015 Jul 9.

PMID:
26160915
30.

Analysis of ER-mitochondria contacts using correlative fluorescence microscopy and soft X-ray tomography of mammalian cells.

Elgass KD, Smith EA, LeGros MA, Larabell CA, Ryan MT.

J Cell Sci. 2015 Aug 1;128(15):2795-804. doi: 10.1242/jcs.169136. Epub 2015 Jun 22.

31.

Splitting up the powerhouse: structural insights into the mechanism of mitochondrial fission.

Richter V, Singh AP, Kvansakul M, Ryan MT, Osellame LD.

Cell Mol Life Sci. 2015 Oct;72(19):3695-707. doi: 10.1007/s00018-015-1950-y. Epub 2015 Jun 10. Review.

PMID:
26059473
32.

FunRich: An open access standalone functional enrichment and interaction network analysis tool.

Pathan M, Keerthikumar S, Ang CS, Gangoda L, Quek CY, Williamson NA, Mouradov D, Sieber OM, Simpson RJ, Salim A, Bacic A, Hill AF, Stroud DA, Ryan MT, Agbinya JI, Mariadason JM, Burgess AW, Mathivanan S.

Proteomics. 2015 Aug;15(15):2597-601. doi: 10.1002/pmic.201400515. Epub 2015 Jun 17.

PMID:
25921073
33.

Characterization of mitochondrial FOXRED1 in the assembly of respiratory chain complex I.

Formosa LE, Mimaki M, Frazier AE, McKenzie M, Stait TL, Thorburn DR, Stroud DA, Ryan MT.

Hum Mol Genet. 2015 May 15;24(10):2952-65. doi: 10.1093/hmg/ddv058. Epub 2015 Feb 12.

PMID:
25678554
34.

The anti-inflammatory potential of a moderately hydrolysed casein and its 5 kDa fraction in in vitro and ex vivo models of the gastrointestinal tract.

Mukhopadhya A, Noronha N, Bahar B, Ryan MT, Murray BA, Kelly PM, O'Loughlin IB, O'Doherty JV, Sweeney T.

Food Funct. 2015 Feb;6(2):612-21. doi: 10.1039/c4fo00689e.

PMID:
25536369
35.

Anti-inflammatory effects of a casein hydrolysate and its peptide-enriched fractions on TNFα-challenged Caco-2 cells and LPS-challenged porcine colonic explants.

Mukhopadhya A, Noronha N, Bahar B, Ryan MT, Murray BA, Kelly PM, O'Loughlin IB, O'Doherty JV, Sweeney T.

Food Sci Nutr. 2014 Nov;2(6):712-23. doi: 10.1002/fsn3.153. Epub 2014 Sep 5.

36.

Mapping biological composition through quantitative phase and absorption X-ray ptychography.

Jones MW, Elgass K, Junker MD, Luu MB, Ryan MT, Peele AG, van Riessen GA.

Sci Rep. 2014 Oct 28;4:6796. doi: 10.1038/srep06796.

37.

Neuronal and astrocyte dysfunction diverges from embryonic fibroblasts in the Ndufs4fky/fky mouse.

Bird MJ, Wijeyeratne XW, Komen JC, Laskowski A, Ryan MT, Thorburn DR, Frazier AE.

Biosci Rep. 2014 Nov 21;34(6):e00151. doi: 10.1042/BSR20140151.

38.

Novel variation in the FABP3 promoter and its association with fatness traits in pigs.

Sweeney T, O'Halloran AM, Hamill RM, Davey GC, Gil M, Southwood OI, Ryan MT.

Meat Sci. 2015 Feb;100:32-40. doi: 10.1016/j.meatsci.2014.09.014. Epub 2014 Sep 28.

PMID:
25306509
39.

Bax targets mitochondria by distinct mechanisms before or during apoptotic cell death: a requirement for VDAC2 or Bak for efficient Bax apoptotic function.

Ma SB, Nguyen TN, Tan I, Ninnis R, Iyer S, Stroud DA, Menard M, Kluck RM, Ryan MT, Dewson G.

Cell Death Differ. 2014 Dec;21(12):1925-35. doi: 10.1038/cdd.2014.119. Epub 2014 Aug 22.

40.

Stalking the mitochondrial ATP synthase: Ina found guilty by association.

Stroud DA, Ryan MT.

EMBO J. 2014 Aug 1;33(15):1617-8. doi: 10.15252/embj.201489069. Epub 2014 Jun 18. No abstract available.

41.

Isolated first metatarsocuneiform joint fusion for correction of metatarsus primus varus deformity and literature review.

Shinabarger AB, Ryan MT, Dzurik M, Burns PR.

J Foot Ankle Surg. 2014 Sep-Oct;53(5):624-7. doi: 10.1053/j.jfas.2014.03.005. Epub 2014 Apr 26. Review.

PMID:
24774989
42.

Structural and functional analysis of MiD51, a dynamin receptor required for mitochondrial fission.

Richter V, Palmer CS, Osellame LD, Singh AP, Elgass K, Stroud DA, Sesaki H, Kvansakul M, Ryan MT.

J Cell Biol. 2014 Feb 17;204(4):477-86. doi: 10.1083/jcb.201311014. Epub 2014 Feb 10.

43.

Effect of seaweed-derived laminarin and fucoidan and zinc oxide on gut morphology, nutrient transporters, nutrient digestibility, growth performance and selected microbial populations in weaned pigs.

Heim G, Walsh AM, Sweeney T, Doyle DN, O'Shea CJ, Ryan MT, O'Doherty JV.

Br J Nutr. 2014 May;111(9):1577-85. doi: 10.1017/S0007114513004224. Epub 2014 Feb 6.

PMID:
24502994
44.

A founder mutation in PET100 causes isolated complex IV deficiency in Lebanese individuals with Leigh syndrome.

Lim SC, Smith KR, Stroud DA, Compton AG, Tucker EJ, Dasvarma A, Gandolfo LC, Marum JE, McKenzie M, Peters HL, Mowat D, Procopis PG, Wilcken B, Christodoulou J, Brown GK, Ryan MT, Bahlo M, Thorburn DR.

Am J Hum Genet. 2014 Feb 6;94(2):209-22. doi: 10.1016/j.ajhg.2013.12.015. Epub 2014 Jan 23.

45.

Mutations in the UQCC1-interacting protein, UQCC2, cause human complex III deficiency associated with perturbed cytochrome b protein expression.

Tucker EJ, Wanschers BF, Szklarczyk R, Mountford HS, Wijeyeratne XW, van den Brand MA, Leenders AM, Rodenburg RJ, Reljić B, Compton AG, Frazier AE, Bruno DL, Christodoulou J, Endo H, Ryan MT, Nijtmans LG, Huynen MA, Thorburn DR.

PLoS Genet. 2013;9(12):e1004034. doi: 10.1371/journal.pgen.1004034. Epub 2013 Dec 26.

46.

Mitochondria: organization of respiratory chain complexes becomes cristae-lized.

Stroud DA, Ryan MT.

Curr Biol. 2013 Nov 4;23(21):R969-71. doi: 10.1016/j.cub.2013.09.035.

47.

Adaptor proteins MiD49 and MiD51 can act independently of Mff and Fis1 in Drp1 recruitment and are specific for mitochondrial fission.

Palmer CS, Elgass KD, Parton RG, Osellame LD, Stojanovski D, Ryan MT.

J Biol Chem. 2013 Sep 20;288(38):27584-93. doi: 10.1074/jbc.M113.479873. Epub 2013 Aug 6.

48.

Assembly of the Bak apoptotic pore: a critical role for the Bak protein α6 helix in the multimerization of homodimers during apoptosis.

Ma S, Hockings C, Anwari K, Kratina T, Fennell S, Lazarou M, Ryan MT, Kluck RM, Dewson G.

J Biol Chem. 2013 Sep 6;288(36):26027-38. doi: 10.1074/jbc.M113.490094. Epub 2013 Jul 26.

49.

HPS publications implement society's "SI Only" position.

Dickson H, Walchuk M, Ryan MT, Little CA, Roessler GS, Classic K, Edwards J.

Health Phys. 2013 Aug;105(2 Suppl 2):S109-10. doi: 10.1097/HP.0b013e31828f0e57. No abstract available.

PMID:
23803662
50.

Supplemental digital content.

Ryan MT.

Health Phys. 2013 May;104(5):453. doi: 10.1097/HP.0b013e318287c86c. No abstract available.

PMID:
23532073

Supplemental Content

Support Center