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Items: 1 to 50 of 170

1.

Proton Transfer versus Hydrogen Bonding in a Reduced Iron Porphyrin Nitrosyl Complex.

Rahman MH, Liu Y, Ryan MD.

Inorg Chem. 2019 Oct 21;58(20):13788-13795. doi: 10.1021/acs.inorgchem.9b01447. Epub 2019 Sep 30.

PMID:
31565930
2.

Selective decontamination of the reactive air pollutant nitrous acid via node-linker cooperativity in a metal-organic framework.

McGrath DT, Ryan MD, MacInnis JJ, VandenBoer TC, Young CJ, Katz MJ.

Chem Sci. 2019 Apr 29;10(21):5576-5581. doi: 10.1039/c9sc01357a. eCollection 2019 Jun 7.

3.

"Therapeutic applications of the 'NPGP' family of viral 2As".

Luke GA, Ryan MD.

Rev Med Virol. 2018 Nov;28(6):e2001. doi: 10.1002/rmv.2001. Epub 2018 Aug 9. Review.

PMID:
30094875
4.

Using the 2A Protein Coexpression System: Multicistronic 2A Vectors Expressing Gene(s) of Interest and Reporter Proteins.

Luke GA, Ryan MD.

Methods Mol Biol. 2018;1755:31-48. doi: 10.1007/978-1-4939-7724-6_3.

PMID:
29671261
5.

In-silico guided discovery of novel CCR9 antagonists.

Zhang X, Cross JB, Romero J, Heifetz A, Humphries E, Hall K, Wu Y, Stucka S, Zhang J, Chandonnet H, Lippa B, Ryan MD, Baber JC.

J Comput Aided Mol Des. 2018 Apr;32(4):573-582. doi: 10.1007/s10822-018-0113-2. Epub 2018 Mar 26.

PMID:
29582229
6.

Solvent Effects on the Intramolecular Charge Transfer Character of N,N-Diaryl Dihydrophenazine Catalysts for Organocatalyzed Atom Transfer Radical Polymerization.

Ryan MD, Theriot JC, Lim CH, Yang H, Lockwood A, Garrison NG, Lincoln SR, Musgrave CB, Miyake GM.

J Polym Sci A Polym Chem. 2017 Sep 15;55(18):3017-3027. doi: 10.1002/pola.28574. Epub 2017 Mar 16.

7.

Altering the Coordination of Iron Porphyrins by Ionic Liquid Nanodomains in Mixed Solvent Systems.

Atifi A, Ryan MD.

Chemistry. 2017 Sep 21;23(53):13076-13086. doi: 10.1002/chem.201701540. Epub 2017 Aug 30.

PMID:
28742232
8.

Strongly Reducing, Visible-Light Organic Photoredox Catalysts as Sustainable Alternatives to Precious Metals.

Du Y, Pearson RM, Lim CH, Sartor SM, Ryan MD, Yang H, Damrauer NH, Miyake GM.

Chemistry. 2017 Aug 16;23(46):10962-10968. doi: 10.1002/chem.201702926. Epub 2017 Aug 1.

9.

Structure-based discovery of LpxC inhibitors.

Zhang J, Chan A, Lippa B, Cross JB, Liu C, Yin N, Romero JA, Lawrence J, Heney R, Herradura P, Goss J, Clark C, Abel C, Zhang Y, Poutsiaka KM, Epie F, Conrad M, Mahamoon A, Nguyen K, Chavan A, Clark E, Li TC, Cheng RK, Wood M, Andersen OA, Brooks M, Kwong J, Barker J, Parr IB, Gu Y, Ryan MD, Coleman S, Metcalf CA 3rd.

Bioorg Med Chem Lett. 2017 Apr 15;27(8):1670-1680. doi: 10.1016/j.bmcl.2017.03.006. Epub 2017 Mar 6.

PMID:
28302397
10.

Redox and Spectroscopic Properties of Iron Porphyrin Nitroxyl in the Presence of Weak Acids.

Rahman MH, Ryan MD.

Inorg Chem. 2017 Mar 20;56(6):3302-3309. doi: 10.1021/acs.inorgchem.6b02665. Epub 2017 Mar 2.

PMID:
28252947
11.

Impact of Light Intensity on Control in Photoinduced Organocatalyzed Atom Transfer Radical Polymerization.

Ryan MD, Pearson RM, French TA, Miyake GM.

Macromolecules. 2017;50(12):4616-4622. doi: 10.1021/acs.macromol.7b00502. Epub 2017 Jun 7.

12.

Intramolecular Charge Transfer and Ion Pairing in N,N-Diaryl Dihydrophenazine Photoredox Catalysts for Efficient Organocatalyzed Atom Transfer Radical Polymerization.

Lim CH, Ryan MD, McCarthy BG, Theriot JC, Sartor SM, Damrauer NH, Musgrave CB, Miyake GM.

J Am Chem Soc. 2017 Jan 11;139(1):348-355. doi: 10.1021/jacs.6b11022. Epub 2016 Dec 27.

13.

Atom Transfer Radical Polymerization of Functionalized Vinyl Monomers Using Perylene as a Visible Light Photocatalyst.

Theriot JC, Ryan MD, French TA, Pearson RM, Miyake GM.

J Vis Exp. 2016 Apr 22;(110):e53571. doi: 10.3791/53571.

14.

'2A-Like' Signal Sequences Mediating Translational Recoding: A Novel Form of Dual Protein Targeting.

Roulston C, Luke GA, de Felipe P, Ruan L, Cope J, Nicholson J, Sukhodub A, Tilsner J, Ryan MD.

Traffic. 2016 Aug;17(8):923-39. doi: 10.1111/tra.12411. Epub 2016 Jun 2.

15.

Discovery of Pyrazolopyridones as a Novel Class of Gyrase B Inhibitors Using Structure Guided Design.

Cross JB, Zhang J, Yang Q, Mesleh MF, Romero JA, Wang B, Bevan D, Poutsiaka KM, Epie F, Moy T, Daniel A, Shotwell J, Chamberlain B, Carter N, Andersen O, Barker J, Ryan MD, Metcalf CA 3rd, Silverman J, Nguyen K, Lippa B, Dolle RE.

ACS Med Chem Lett. 2016 Feb 16;7(4):374-8. doi: 10.1021/acsmedchemlett.5b00368. eCollection 2016 Apr 14.

16.

Organocatalyzed atom transfer radical polymerization driven by visible light.

Theriot JC, Lim CH, Yang H, Ryan MD, Musgrave CB, Miyake GM.

Science. 2016 May 27;352(6289):1082-6. doi: 10.1126/science.aaf3935. Epub 2016 Mar 31.

17.

X-ray Structure and Properties of the Ferrous Octaethylporphyrin Nitroxyl Complex.

Kundakarla N, Lindeman S, Rahman MH, Ryan MD.

Inorg Chem. 2016 Mar 7;55(5):2070-5. doi: 10.1021/acs.inorgchem.5b02384. Epub 2016 Feb 17.

PMID:
26885766
18.

Fragment-based discovery of DNA gyrase inhibitors targeting the ATPase subunit of GyrB.

Mesleh MF, Cross JB, Zhang J, Kahmann J, Andersen OA, Barker J, Cheng RK, Felicetti B, Wood M, Hadfield AT, Scheich C, Moy TI, Yang Q, Shotwell J, Nguyen K, Lippa B, Dolle R, Ryan MD.

Bioorg Med Chem Lett. 2016 Feb 15;26(4):1314-8. doi: 10.1016/j.bmcl.2016.01.009. Epub 2016 Jan 6.

PMID:
26786695
19.

Spectroscopic Evidence of Nanodomains in THF/RTIL Mixtures: Spectroelectrochemical and Voltammetric Study of Nickel Porphyrins.

Atifi A, Ryan MD.

Anal Chem. 2015 Dec 15;87(24):12245-53. doi: 10.1021/acs.analchem.5b03411. Epub 2015 Nov 20.

PMID:
26554502
20.

Attenuation of dengue (and other RNA viruses) with codon pair recoding can be explained by increased CpG/UpA dinucleotide frequencies.

Simmonds P, Tulloch F, Evans DJ, Ryan MD.

Proc Natl Acad Sci U S A. 2015 Jul 14;112(28):E3633-4. doi: 10.1073/pnas.1507339112. Epub 2015 Jun 12. No abstract available.

21.

RNA virus attenuation by codon pair deoptimisation is an artefact of increases in CpG/UpA dinucleotide frequencies.

Tulloch F, Atkinson NJ, Evans DJ, Ryan MD, Simmonds P.

Elife. 2014 Dec 9;3:e04531. doi: 10.7554/eLife.04531.

22.

FMDV replicons encoding green fluorescent protein are replication competent.

Tulloch F, Pathania U, Luke GA, Nicholson J, Stonehouse NJ, Rowlands DJ, Jackson T, Tuthill T, Haas J, Lamond AI, Ryan MD.

J Virol Methods. 2014 Dec;209:35-40. doi: 10.1016/j.jviromet.2014.08.020. Epub 2014 Sep 4.

23.
24.

Lost in translation: The biogenesis of non-LTR retrotransposon proteins.

Luke GA, Roulston C, Odon V, de Felipe P, Sukhodub A, Ryan MD.

Mob Genet Elements. 2013 Nov 1;3(6):e27525. Epub 2013 Dec 13.

25.

Optimisation of the foot-and-mouth disease virus 2A co-expression system for biomedical applications.

Minskaia E, Nicholson J, Ryan MD.

BMC Biotechnol. 2013 Aug 22;13:67. doi: 10.1186/1472-6750-13-67.

26.

In situ study of the photodegradation of carbofuran deposited on TiO2 film under UV light, using ATR-FTIR coupled to HS-MCR-ALS.

Atifi A, Czarnecki K, Mountacer H, Ryan MD.

Environ Sci Technol. 2013 Aug 6;47(15):8650-7. doi: 10.1021/es400800v. Epub 2013 Jul 29.

PMID:
23895580
27.

Protein coexpression using FMDV 2A: effect of "linker" residues.

Minskaia E, Ryan MD.

Biomed Res Int. 2013;2013:291730. doi: 10.1155/2013/291730. Epub 2013 Jun 12.

28.

APE-type non-LTR retrotransposons of multicellular organisms encode virus-like 2A oligopeptide sequences, which mediate translational recoding during protein synthesis.

Odon V, Luke GA, Roulston C, de Felipe P, Ruan L, Escuin-Ordinas H, Brown JD, Ryan MD, Sukhodub A.

Mol Biol Evol. 2013 Aug;30(8):1955-65. doi: 10.1093/molbev/mst102. Epub 2013 May 31.

29.

Theiler's murine encephalomyelitis virus contrasts with encephalomyocarditis and foot-and-mouth disease viruses in its functional utilization of the StopGo non-standard translation mechanism.

Loughran G, Libbey JE, Uddowla S, Scallan MF, Ryan MD, Fujinami RS, Rieder E, Atkins JF.

J Gen Virol. 2013 Feb;94(Pt 2):348-53. doi: 10.1099/vir.0.047571-0. Epub 2012 Oct 24.

30.

2A peptides provide distinct solutions to driving stop-carry on translational recoding.

Sharma P, Yan F, Doronina VA, Escuin-Ordinas H, Ryan MD, Brown JD.

Nucleic Acids Res. 2012 Apr;40(7):3143-51. doi: 10.1093/nar/gkr1176. Epub 2011 Dec 2.

31.

Rank order entropy: why one metric is not enough.

McLellan MR, Ryan MD, Breneman CM.

J Chem Inf Model. 2011 Sep 26;51(9):2302-19. doi: 10.1021/ci200170k. Epub 2011 Aug 29.

32.

Genome organization and translation products of Providence virus: insight into a unique tetravirus.

Walter CT, Pringle FM, Nakayinga R, de Felipe P, Ryan MD, Ball LA, Dorrington RA.

J Gen Virol. 2010 Nov;91(Pt 11):2826-35. doi: 10.1099/vir.0.023796-0. Epub 2010 Aug 11.

PMID:
20702652
33.

Infrared spectroelectrochemical reduction of iron porphyrin complexes.

Wei Z, Ryan MD.

Inorg Chem. 2010 Aug 2;49(15):6948-54. doi: 10.1021/ic100614h.

PMID:
20604563
34.

Signed outside: a surface marker system for transgenic cytoplasmic proteins.

Wohlgensinger V, Seger R, Ryan MD, Reichenbach J, Siler U.

Gene Ther. 2010 Oct;17(10):1193-9. doi: 10.1038/gt.2010.73. Epub 2010 May 6.

PMID:
20445581
35.

Inhibition of 2A-mediated 'cleavage' of certain artificial polyproteins bearing N-terminal signal sequences.

de Felipe P, Luke GA, Brown JD, Ryan MD.

Biotechnol J. 2010 Feb;5(2):213-23. doi: 10.1002/biot.200900134.

36.
37.

Creatinine clearance and blood pressure: a 34-year circadian study.

Kanabrocki EL, Sothern RB, Sackett-Lundeen L, Ryan MD, Johnson M, Foley S, Dawson S, Ocasio T, McCormick JB, Haus E, Kaplan E, Nemchausky B.

Clin Ter. 2008 Nov-Dec;159(6):409-17.

PMID:
19169600
38.

Foot and Mouth's Achilles' heel?

Atkins JF, Ryan MD.

Nat Biotechnol. 2008 Dec;26(12):1335-6. doi: 10.1038/nbt1208-1335c. No abstract available.

PMID:
19060865
39.

Circadian characteristics of serum calcium, magnesium and eight trace elements and of their metallo-moieties in urine of healthy middle-aged men.

Kanabrocki EL, Sothern RB, Ryan MD, Kahn S, Augustine G, Johnson C, Foley S, Gathing A, Eastman G, Friedman N, Nemchausky BA, Kaplan E.

Clin Ter. 2008 Sep-Oct;159(5):329-46.

PMID:
18998036
40.

Dissection of a co-translational nascent chain separation event.

Doronina VA, de Felipe P, Wu C, Sharma P, Sachs MS, Ryan MD, Brown JD.

Biochem Soc Trans. 2008 Aug;36(Pt 4):712-6. doi: 10.1042/BST0360712.

PMID:
18631146
41.

Site-specific release of nascent chains from ribosomes at a sense codon.

Doronina VA, Wu C, de Felipe P, Sachs MS, Ryan MD, Brown JD.

Mol Cell Biol. 2008 Jul;28(13):4227-39. doi: 10.1128/MCB.00421-08. Epub 2008 May 5.

42.

Uric acid and renal function in multiple sclerosis.

Kanabrocki EL, Ryan MD, Hermida RC, Ayala DE, McCormick JB, Dawson S, Lojo L, Hoffman HS, Siegel G, Friedman N, Eladasori B, Parachuri R, Nemchausky BA.

Clin Ter. 2008 Jan-Feb;159(1):35-40.

PMID:
18399261
43.

Occurrence, function and evolutionary origins of '2A-like' sequences in virus genomes.

Luke GA, de Felipe P, Lukashev A, Kallioinen SE, Bruno EA, Ryan MD.

J Gen Virol. 2008 Apr;89(Pt 4):1036-42. doi: 10.1099/vir.0.83428-0.

44.

Expression of heterologous genes in oncolytic adenoviruses using picornaviral 2A sequences that trigger ribosome skipping.

Funston GM, Kallioinen SE, de Felipe P, Ryan MD, Iggo RD.

J Gen Virol. 2008 Feb;89(Pt 2):389-96. doi: 10.1099/vir.0.83444-0.

PMID:
18198369
45.

Twenty-nine year study on circadian distribution of urinary zinc levels of same male subjects.

Kanabrocki EL, Ryan MD, Marks G, Friedman NC, Kaplan E, Nemchausky BA.

Clin Ter. 2007 Sep-Oct;158(5):403-8.

PMID:
18062346
46.

Highly potent inhibitors of methionine aminopeptidase-2 based on a 1,2,4-triazole pharmacophore.

Marino JP Jr, Fisher PW, Hofmann GA, Kirkpatrick RB, Janson CA, Johnson RK, Ma C, Mattern M, Meek TD, Ryan MD, Schulz C, Smith WW, Tew DG, Tomazek TA Jr, Veber DF, Xiong WC, Yamamoto Y, Yamashita K, Yang G, Thompson SK.

J Med Chem. 2007 Aug 9;50(16):3777-85. Epub 2007 Jul 18.

PMID:
17636946
47.

Circadian distribution of serum cytokines in multiple sclerosis.

Kanabrocki EL, Ryan MD, Lathers D, Achille N, Young MR, Cauteren JV, Foley S, Johnson MC, Friedman NC, Siegel G, Nemchausky BA.

Clin Ter. 2007 Mar-Apr;158(2):157-62.

PMID:
17566518
48.
49.

A novel cleavage site within the potato leafroll virus P1 polyprotein.

Li X, Halpin C, Ryan MD.

J Gen Virol. 2007 May;88(Pt 5):1620-3.

PMID:
17412995
50.

Relationships between 24h observations in intraocular pressure vs blood pressure, heart rate, nitric oxide and age in the medical chronobiology aging project.

Perlman JI, Delany CM, Sothern RB, Skolnick KA, Murray D, Jacobs RW, Shue JL, Kaplan E, Friedman NC, Nemchausky BA, Ryan MD, Kanabrocki EL.

Clin Ter. 2007 Jan-Feb;158(1):31-47.

PMID:
17405658

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