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Items: 1 to 50 of 56

1.

Microhomology-mediated end joining drives complex rearrangements and over expression of MYC and PVT1 in multiple myeloma.

Mikulasova A, Ashby C, Tytarenko RG, Qu P, Rosenthal A, Dent JA, Ryan KR, Bauer MA, Wardell CP, Hoering A, Mavrommatis K, Trotter M, Deshpande S, Yaccoby S, Tian E, Keats J, Auclair D, Jackson GH, Davies FE, Thakurta A, Morgan GJ, Walker BA.

Haematologica. 2019 Jun 20. pii: haematol.2019.217927. doi: 10.3324/haematol.2019.217927. [Epub ahead of print]

2.

Vasoplegia after pediatric cardiac transplantation in patients supported with a continuous flow ventricular assist device.

Sacks LD, Hollander SA, Zhang Y, Ryan KR, Ford MA, Maeda K, Murray JM, Almond CS, Kwiatkowski DM.

J Thorac Cardiovasc Surg. 2019 Feb 6. pii: S0022-5223(19)30315-0. doi: 10.1016/j.jtcvs.2019.01.100. [Epub ahead of print]

PMID:
30929985
3.

Engineering the S-Layer of Caulobacter crescentus as a Foundation for Stable, High-Density, 2D Living Materials.

Charrier M, Li D, Mann VR, Yun L, Jani S, Rad B, Cohen BE, Ashby PD, Ryan KR, Ajo-Franklin CM.

ACS Synth Biol. 2019 Jan 18;8(1):181-190. doi: 10.1021/acssynbio.8b00448. Epub 2019 Jan 7.

4.

Validation of a clinically-relevant rodent model of statin-associated muscle symptoms for use in pharmacological studies.

Irwin JC, Fenning AS, Ryan KR, Vella RK.

Toxicol Appl Pharmacol. 2018 Dec 1;360:78-87. doi: 10.1016/j.taap.2018.09.040. Epub 2018 Sep 28.

PMID:
30268577
5.

Activation of RHO-1 in cholinergic motor neurons competes with dopamine signalling to control locomotion.

Essmann CL, Ryan KR, Elmi M, Bryon-Dodd K, Porter A, Vaughan A, McMullan R, Nurrish S.

PLoS One. 2018 Sep 21;13(9):e0204057. doi: 10.1371/journal.pone.0204057. eCollection 2018.

6.

The contribution of Nintendo Wii Fit series in the field of health: a systematic review and meta-analysis.

Tripette J, Murakami H, Ryan KR, Ohta Y, Miyachi M.

PeerJ. 2017 Sep 5;5:e3600. doi: 10.7717/peerj.3600. eCollection 2017.

7.

Strategies to address the shortcomings of commonly used advanced chronic heart failure descriptors to improve recruitment in palliative care research: A parallel mixed-methods feasibility study.

Kane PM, Murtagh FEM, Ryan KR, Brice M, Mahon NG, McAdam B, McQuillan R, O'Gara G, Raleigh C, Tracey C, Howley C, Higginson IJ, Daveson BA; BuildCARE.

Palliat Med. 2018 Feb;32(2):517-524. doi: 10.1177/0269216317706426. Epub 2017 May 10.

8.

In vitro cardiotoxicity assessment of environmental chemicals using an organotypic human induced pluripotent stem cell-derived model.

Sirenko O, Grimm FA, Ryan KR, Iwata Y, Chiu WA, Parham F, Wignall JA, Anson B, Cromwell EF, Behl M, Rusyn I, Tice RR.

Toxicol Appl Pharmacol. 2017 May 1;322:60-74. doi: 10.1016/j.taap.2017.02.020. Epub 2017 Mar 1.

9.

Comparative pulmonary toxicity of inhaled metalworking fluids in rats and mice.

Ryan KR, Cesta MF, Herbert R, Brix A, Cora M, Witt K, Kissling G, Morgan DL.

Toxicol Ind Health. 2017 May;33(5):385-405. doi: 10.1177/0748233716653912. Epub 2016 Jun 23.

PMID:
27343050
10.

Neurite outgrowth in human induced pluripotent stem cell-derived neurons as a high-throughput screen for developmental neurotoxicity or neurotoxicity.

Ryan KR, Sirenko O, Parham F, Hsieh JH, Cromwell EF, Tice RR, Behl M.

Neurotoxicology. 2016 Mar;53:271-281. doi: 10.1016/j.neuro.2016.02.003. Epub 2016 Feb 4.

PMID:
26854185
11.

Inference of Low and High-Grade Glioma Gene Regulatory Networks Delineates the Role of Rnd3 in Establishing Multiple Hallmarks of Cancer.

Clarke K, Daubon T, Turan N, Soulet F, Mohd Zahari M, Ryan KR, Durant S, He S, Herbert J, Ankers J, Heath JK, Bjerkvig R, Bicknell R, Hotchin NA, Bikfalvi A, Falciani F.

PLoS Genet. 2015 Jul 1;11(7):e1005325. doi: 10.1371/journal.pgen.1005325. eCollection 2015 Jul.

12.

Cell cycle-dependent adaptor complex for ClpXP-mediated proteolysis directly integrates phosphorylation and second messenger signals.

Smith SC, Joshi KK, Zik JJ, Trinh K, Kamajaya A, Chien P, Ryan KR.

Proc Natl Acad Sci U S A. 2014 Sep 30;111(39):14229-34. doi: 10.1073/pnas.1407862111. Epub 2014 Sep 2.

13.

Low energy structural dynamics and constrained libration of Li(NH3)4, the lowest melting point metal.

Seel AG, Zurek E, Ramirez-Cuesta AJ, Ryan KR, Lodge MT, Edwards PP.

Chem Commun (Camb). 2014 Sep 25;50(74):10778-81. doi: 10.1039/c4cc03397c.

PMID:
24988060
14.

A high-throughput scintillation proximity assay for sphingosine-1-phosphate lyase.

Kashem MA, Wa C, Wolak JP, Grafos NS, Ryan KR, Sanville-Ross ML, Fogarty KE, Rybina IV, Shoultz A, Molinaro T, Desai SN, Rajan A, Huber JD, Nelson RM.

Assay Drug Dev Technol. 2014 Jun;12(5):293-302. doi: 10.1089/adt.2014.575. Epub 2014 May 20.

PMID:
24846303
15.

Circulating monocytes are reduced by sphingosine-1-phosphate receptor modulators independently of S1P3.

Lewis ND, Haxhinasto SA, Anderson SM, Stefanopoulos DE, Fogal SE, Adusumalli P, Desai SN, Patnaude LA, Lukas SM, Ryan KR, Slavin AJ, Brown ML, Modis LK.

J Immunol. 2013 Apr 1;190(7):3533-40. doi: 10.4049/jimmunol.1201810. Epub 2013 Feb 22.

16.

The structure, thermal properties and phase transformations of the cubic polymorph of magnesium tetrahydroborate.

David WI, Callear SK, Jones MO, Aeberhard PC, Culligan SD, Pohl AH, Johnson SR, Ryan KR, Parker JE, Edwards PP, Nuttall CJ, Amieiro-Fonseca A.

Phys Chem Chem Phys. 2012 Sep 7;14(33):11800-7. doi: 10.1039/c2cp23439d. Epub 2012 Jul 25.

PMID:
22828487
17.

Plakoglobin-dependent regulation of keratinocyte apoptosis by Rnd3.

Ryan KR, Lock FE, Heath JK, Hotchin NA.

J Cell Sci. 2012 Jul 1;125(Pt 13):3202-9. doi: 10.1242/jcs.101931. Epub 2012 Mar 27.

18.

Differential regulation of adhesion complex turnover by ROCK1 and ROCK2.

Lock FE, Ryan KR, Poulter NS, Parsons M, Hotchin NA.

PLoS One. 2012;7(2):e31423. doi: 10.1371/journal.pone.0031423. Epub 2012 Feb 13.

19.

An essential tyrosine phosphatase homolog regulates cell separation, outer membrane integrity, and morphology in Caulobacter crescentus.

Shapland EB, Reisinger SJ, Bajwa AK, Ryan KR.

J Bacteriol. 2011 Sep;193(17):4361-70. doi: 10.1128/JB.00185-11. Epub 2011 Jun 24.

20.

A combined experimental inelastic neutron scattering, Raman and ab initio lattice dynamics study of α-lithium amidoborane.

Ryan KR, Ramirez-Cuesta AJ, Refson K, Jones MO, Edwards PP, David WI.

Phys Chem Chem Phys. 2011 Jul 14;13(26):12249-53. doi: 10.1039/c1cp20587k. Epub 2011 Jun 2.

PMID:
21637868
21.

Broad dissemination of plasmid-mediated quinolone resistance genes in sediments of two urban coastal wetlands.

Cummings DE, Archer KF, Arriola DJ, Baker PA, Faucett KG, Laroya JB, Pfeil KL, Ryan CR, Ryan KR, Zuill DE.

Environ Sci Technol. 2011 Jan 15;45(2):447-54. doi: 10.1021/es1029206. Epub 2010 Dec 8.

PMID:
21141884
22.

Potassium(I) amidotrihydroborate: structure and hydrogen release.

Diyabalanage HV, Nakagawa T, Shrestha RP, Semelsberger TA, Davis BL, Scott BL, Burrell AK, David WI, Ryan KR, Jones MO, Edwards PP.

J Am Chem Soc. 2010 Sep 1;132(34):11836-7. doi: 10.1021/ja100167z.

PMID:
20687546
23.

Stepwise phase transition in the formation of lithium amidoborane.

Wu C, Wu G, Xiong Z, David WI, Ryan KR, Jones MO, Edwards PP, Chu H, Chen P.

Inorg Chem. 2010 May 3;49(9):4319-23. doi: 10.1021/ic100308j.

PMID:
20353150
24.

Calpain plays a central role in 1-methyl-4-phenylpyridinium (MPP+)-induced neurotoxicity in cerebellar granule neurons.

Harbison RA, Ryan KR, Wilkins HM, Schroeder EK, Loucks FA, Bouchard RJ, Linseman DA.

Neurotox Res. 2011 Apr;19(3):374-88. doi: 10.1007/s12640-010-9172-4. Epub 2010 Mar 24.

PMID:
20333497
25.
26.

Mutations that alter RcdA surface residues decouple protein localization and CtrA proteolysis in Caulobacter crescentus.

Taylor JA, Wilbur JD, Smith SC, Ryan KR.

J Mol Biol. 2009 Nov 20;394(1):46-60. doi: 10.1016/j.jmb.2009.08.076. Epub 2009 Sep 8.

PMID:
19747489
27.

Pattern recognition receptor expression is not impaired in patients with chronic mucocutanous candidiasis with or without autoimmune polyendocrinopathy candidiasis ectodermal dystrophy.

Hong M, Ryan KR, Arkwright PD, Gennery AR, Costigan C, Dominguez M, Denning DW, McConnell V, Cant AJ, Abinun M, Spickett GP, Swan DC, Gillespie CS, Young DA, Lilic D.

Clin Exp Immunol. 2009 Apr;156(1):40-51. doi: 10.1111/j.1365-2249.2009.03873.x. Epub 2009 Jan 22.

28.

Impaired dendritic cell maturation and cytokine production in patients with chronic mucocutanous candidiasis with or without APECED.

Ryan KR, Hong M, Arkwright PD, Gennery AR, Costigan C, Dominguez M, Denning D, McConnell V, Cant AJ, Abinun M, Spickett GP, Lilic D.

Clin Exp Immunol. 2008 Dec;154(3):406-14. doi: 10.1111/j.1365-2249.2008.03778.x.

29.

Who's in charge here? Regulating cell cycle regulators.

Bowers LM, Shapland EB, Ryan KR.

Curr Opin Microbiol. 2008 Dec;11(6):547-52. doi: 10.1016/j.mib.2008.09.019. Epub 2008 Nov 3. Review.

PMID:
18955157
30.

Autoantibodies against type I interferons as an additional diagnostic criterion for autoimmune polyendocrine syndrome type I.

Meloni A, Furcas M, Cetani F, Marcocci C, Falorni A, Perniola R, Pura M, Bøe Wolff AS, Husebye ES, Lilic D, Ryan KR, Gennery AR, Cant AJ, Abinun M, Spickett GP, Arkwright PD, Denning D, Costigan C, Dominguez M, McConnell V, Willcox N, Meager A.

J Clin Endocrinol Metab. 2008 Nov;93(11):4389-97. doi: 10.1210/jc.2008-0935. Epub 2008 Aug 26.

PMID:
18728167
31.

Death, adaptation and regulation: the three pillars of immune tolerance restrict the risk of autoimmune disease caused by molecular mimicry.

Ryan KR, Patel SD, Stephens LA, Anderton SM.

J Autoimmun. 2007 Dec;29(4):262-71. Epub 2007 Sep 17. Review.

PMID:
17870412
32.

DivL performs critical cell cycle functions in Caulobacter crescentus independent of kinase activity.

Reisinger SJ, Huntwork S, Viollier PH, Ryan KR.

J Bacteriol. 2007 Nov;189(22):8308-20. Epub 2007 Sep 7.

33.

Controlled assembly of micrometer-sized spheres: theory and application.

Tull EJ, Bartlett PN, Ryan KR.

Langmuir. 2007 Jul 3;23(14):7859-73. Epub 2007 Jun 7.

PMID:
17552546
34.

Regulation of the bacterial cell cycle by an integrated genetic circuit.

Biondi EG, Reisinger SJ, Skerker JM, Arif M, Perchuk BS, Ryan KR, Laub MT.

Nature. 2006 Dec 14;444(7121):899-904. Epub 2006 Nov 29.

PMID:
17136100
36.

A dynamically localized protease complex and a polar specificity factor control a cell cycle master regulator.

McGrath PT, Iniesta AA, Ryan KR, Shapiro L, McAdams HH.

Cell. 2006 Feb 10;124(3):535-47.

37.
38.

CD4+CD25+ T-regulatory cells are decreased in patients with autoimmune polyendocrinopathy candidiasis ectodermal dystrophy.

Ryan KR, Lawson CA, Lorenzi AR, Arkwright PD, Isaacs JD, Lilic D.

J Allergy Clin Immunol. 2005 Nov;116(5):1158-9. Epub 2005 Oct 10. No abstract available.

PMID:
16275391
39.

Proteasome inhibition elicits a biphasic effect on neuronal apoptosis via differential regulation of pro-survival and pro-apoptotic transcription factors.

Butts BD, Hudson HR, Linseman DA, Le SS, Ryan KR, Bouchard RJ, Heidenreich KA.

Mol Cell Neurosci. 2005 Oct;30(2):279-89.

PMID:
16112871
40.

Fas-mediated death and sensory adaptation limit the pathogenic potential of autoreactive T cells after strong antigenic stimulation.

Ryan KR, McCue D, Anderton SM.

J Leukoc Biol. 2005 Jul;78(1):43-50. Epub 2005 Apr 7.

PMID:
15817704
41.

Observer variability when evaluating patient movement from electronic portal images of pelvic radiotherapy fields.

Lewis DG, Ryan KR, Smith CW.

Radiother Oncol. 2005 Mar;74(3):275-81. Epub 2004 Dec 23.

PMID:
15763308
42.

Activation thresholds determine susceptibility to peptide-induced tolerance in a heterogeneous myelin-reactive T cell repertoire.

McCue D, Ryan KR, Wraith DC, Anderton SM.

J Neuroimmunol. 2004 Nov;156(1-2):96-106.

PMID:
15465600
43.

Recruitment of a cytoplasmic response regulator to the cell pole is linked to its cell cycle-regulated proteolysis.

Ryan KR, Huntwork S, Shapiro L.

Proc Natl Acad Sci U S A. 2004 May 11;101(19):7415-20. Epub 2004 Apr 29.

44.

Modification of peptide interaction with MHC creates TCR partial agonists.

Ryan KR, McNeil LK, Dao C, Jensen PE, Evavold BD.

Cell Immunol. 2004 Jan;227(1):70-8.

PMID:
15051516
45.

Fluorescence bleaching reveals asymmetric compartment formation prior to cell division in Caulobacter.

Judd EM, Ryan KR, Moerner WE, Shapiro L, McAdams HH.

Proc Natl Acad Sci U S A. 2003 Jul 8;100(14):8235-40. Epub 2003 Jun 24.

46.

Temporal and spatial regulation in prokaryotic cell cycle progression and development.

Ryan KR, Shapiro L.

Annu Rev Biochem. 2003;72:367-94. Epub 2003 Mar 19. Review.

PMID:
12651741
48.
49.
50.

Persistence of peptide-induced CD4+ T cell anergy in vitro.

Ryan KR, Evavold BD.

J Exp Med. 1998 Jan 5;187(1):89-96.

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