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Items: 1 to 50 of 207

1.

Targeted inhibition of PI3Kα/δ is synergistic with BCL-2 blockade in genetically defined subtypes of DLBCL.

Bojarczuk K, Wienand K, Ryan JA, Chen L, Villalobos-Ortiz M, Mandato E, Stachura J, Letai A, Lawton LN, Chapuy B, Shipp MA.

Blood. 2019 Jan 3;133(1):70-80. doi: 10.1182/blood-2018-08-872465. Epub 2018 Oct 15.

PMID:
30322870
2.

Which resources are most helpful to support development of an ePortfolio?

Ryan JA.

Br J Nurs. 2018 Mar 8;27(5):266-271. doi: 10.12968/bjon.2018.27.5.266.

PMID:
29517326
3.

Iterative optimization yields Mcl-1-targeting stapled peptides with selective cytotoxicity to Mcl-1-dependent cancer cells.

Rezaei Araghi R, Bird GH, Ryan JA, Jenson JM, Godes M, Pritz JR, Grant RA, Letai A, Walensky LD, Keating AE.

Proc Natl Acad Sci U S A. 2018 Jan 30;115(5):E886-E895. doi: 10.1073/pnas.1712952115. Epub 2018 Jan 16.

4.

Epistatic mutations in PUMA BH3 drive an alternate binding mode to potently and selectively inhibit anti-apoptotic Bfl-1.

Jenson JM, Ryan JA, Grant RA, Letai A, Keating AE.

Elife. 2017 Jun 8;6. pii: e25541. doi: 10.7554/eLife.25541.

5.

Developmental Regulation of Mitochondrial Apoptosis by c-Myc Governs Age- and Tissue-Specific Sensitivity to Cancer Therapeutics.

Sarosiek KA, Fraser C, Muthalagu N, Bhola PD, Chang W, McBrayer SK, Cantlon A, Fisch S, Golomb-Mello G, Ryan JA, Deng J, Jian B, Corbett C, Goldenberg M, Madsen JR, Liao R, Walsh D, Sedivy J, Murphy DJ, Carrasco DR, Robinson S, Moslehi J, Letai A.

Cancer Cell. 2017 Jan 9;31(1):142-156. doi: 10.1016/j.ccell.2016.11.011. Epub 2016 Dec 22.

6.

Functionally identifiable apoptosis-insensitive subpopulations determine chemoresistance in acute myeloid leukemia.

Bhola PD, Mar BG, Lindsley RC, Ryan JA, Hogdal LJ, Vo TT, DeAngelo DJ, Galinsky I, Ebert BL, Letai A.

J Clin Invest. 2016 Oct 3;126(10):3827-3836. doi: 10.1172/JCI82908. Epub 2016 Sep 6.

7.

The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice.

Townsend EC, Murakami MA, Christodoulou A, Christie AL, Köster J, DeSouza TA, Morgan EA, Kallgren SP, Liu H, Wu SC, Plana O, Montero J, Stevenson KE, Rao P, Vadhi R, Andreeff M, Armand P, Ballen KK, Barzaghi-Rinaudo P, Cahill S, Clark RA, Cooke VG, Davids MS, DeAngelo DJ, Dorfman DM, Eaton H, Ebert BL, Etchin J, Firestone B, Fisher DC, Freedman AS, Galinsky IA, Gao H, Garcia JS, Garnache-Ottou F, Graubert TA, Gutierrez A, Halilovic E, Harris MH, Herbert ZT, Horwitz SM, Inghirami G, Intlekofer AM, Ito M, Izraeli S, Jacobsen ED, Jacobson CA, Jeay S, Jeremias I, Kelliher MA, Koch R, Konopleva M, Kopp N, Kornblau SM, Kung AL, Kupper TS, LeBoeuf NR, LaCasce AS, Lees E, Li LS, Look AT, Murakami M, Muschen M, Neuberg D, Ng SY, Odejide OO, Orkin SH, Paquette RR, Place AE, Roderick JE, Ryan JA, Sallan SE, Shoji B, Silverman LB, Soiffer RJ, Steensma DP, Stegmaier K, Stone RM, Tamburini J, Thorner AR, van Hummelen P, Wadleigh M, Wiesmann M, Weng AP, Wuerthner JU, Williams DA, Wollison BM, Lane AA, Letai A, Bertagnolli MM, Ritz J, Brown M, Long H, Aster JC, Shipp MA, Griffin JD, Weinstock DM.

Cancer Cell. 2016 Jul 11;30(1):183. doi: 10.1016/j.ccell.2016.06.008. Epub 2016 Jul 11. No abstract available.

8.

The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice.

Townsend EC, Murakami MA, Christodoulou A, Christie AL, Köster J, DeSouza TA, Morgan EA, Kallgren SP, Liu H, Wu SC, Plana O, Montero J, Stevenson KE, Rao P, Vadhi R, Andreeff M, Armand P, Ballen KK, Barzaghi-Rinaudo P, Cahill S, Clark RA, Cooke VG, Davids MS, DeAngelo DJ, Dorfman DM, Eaton H, Ebert BL, Etchin J, Firestone B, Fisher DC, Freedman AS, Galinsky IA, Gao H, Garcia JS, Garnache-Ottou F, Graubert TA, Gutierrez A, Halilovic E, Harris MH, Herbert ZT, Horwitz SM, Inghirami G, Intlekofer AM, Ito M, Izraeli S, Jacobsen ED, Jacobson CA, Jeay S, Jeremias I, Kelliher MA, Koch R, Konopleva M, Kopp N, Kornblau SM, Kung AL, Kupper TS, LeBoeuf NR, LaCasce AS, Lees E, Li LS, Look AT, Murakami M, Muschen M, Neuberg D, Ng SY, Odejide OO, Orkin SH, Paquette RR, Place AE, Roderick JE, Ryan JA, Sallan SE, Shoji B, Silverman LB, Soiffer RJ, Steensma DP, Stegmaier K, Stone RM, Tamburini J, Thorner AR, van Hummelen P, Wadleigh M, Wiesmann M, Weng AP, Wuerthner JU, Williams DA, Wollison BM, Lane AA, Letai A, Bertagnolli MM, Ritz J, Brown M, Long H, Aster JC, Shipp MA, Griffin JD, Weinstock DM.

Cancer Cell. 2016 Apr 11;29(4):574-586. doi: 10.1016/j.ccell.2016.03.008. Erratum in: Cancer Cell. 2016 Jul 11;30(1):183.

9.

Distribution, prevalence, and pathology of a microsporidian infecting freshwater sculpins.

Ryan JA, Kohler SL.

Dis Aquat Organ. 2016 Mar 30;118(3):195-206. doi: 10.3354/dao02974.

PMID:
27025307
10.

Rapid Optimization of Mcl-1 Inhibitors using Stapled Peptide Libraries Including Non-Natural Side Chains.

Rezaei Araghi R, Ryan JA, Letai A, Keating AE.

ACS Chem Biol. 2016 May 20;11(5):1238-44. doi: 10.1021/acschembio.5b01002. Epub 2016 Feb 19.

11.

Activity of the Type II JAK2 Inhibitor CHZ868 in B Cell Acute Lymphoblastic Leukemia.

Wu SC, Li LS, Kopp N, Montero J, Chapuy B, Yoda A, Christie AL, Liu H, Christodoulou A, van Bodegom D, van der Zwet J, Layer JV, Tivey T, Lane AA, Ryan JA, Ng SY, DeAngelo DJ, Stone RM, Steensma D, Wadleigh M, Harris M, Mandon E, Ebel N, Andraos R, Romanet V, Dölemeyer A, Sterker D, Zender M, Rodig SJ, Murakami M, Hofmann F, Kuo F, Eck MJ, Silverman LB, Sallan SE, Letai A, Baffert F, Vangrevelinghe E, Radimerski T, Gaul C, Weinstock DM.

Cancer Cell. 2015 Jul 13;28(1):29-41. doi: 10.1016/j.ccell.2015.06.005.

12.

Self-assembly and characterization of transferrin-gold nanoconstructs and their interaction with bio-interfaces.

McDonagh BH, Volden S, Lystvet SM, Singh G, Ese MH, Ryan JA, Lindgren M, Sandvig A, Sandvig I, Glomm WR.

Nanoscale. 2015 May 7;7(17):8062-70. doi: 10.1039/c5nr01284h.

PMID:
25873450
13.

Two-phase (low-dose) computed tomography is as effective as 4D-CT for identifying enlarged parathyroid glands.

Campbell MJ, Sicuro P, Alseidi A, Blackmore CC, Ryan JA Jr.

Int J Surg. 2015 Feb;14:80-4. doi: 10.1016/j.ijsu.2015.01.005. Epub 2015 Jan 15.

14.

Designed BH3 peptides with high affinity and specificity for targeting Mcl-1 in cells.

Foight GW, Ryan JA, Gullá SV, Letai A, Keating AE.

ACS Chem Biol. 2014 Sep 19;9(9):1962-8. doi: 10.1021/cb500340w. Epub 2014 Jul 23.

15.

Extended neoadjuvant chemotherapy for borderline resectable pancreatic cancer demonstrates promising postoperative outcomes and survival.

Rose JB, Rocha FG, Alseidi A, Biehl T, Moonka R, Ryan JA, Lin B, Picozzi V, Helton S.

Ann Surg Oncol. 2014 May;21(5):1530-7. doi: 10.1245/s10434-014-3486-z. Epub 2014 Jan 29. Erratum in: Ann Surg Oncol. 2014 May;21(5):1538. Dosage error in article text.

PMID:
24473642
16.

High mitochondrial priming sensitizes hESCs to DNA-damage-induced apoptosis.

Liu JC, Guan X, Ryan JA, Rivera AG, Mock C, Agrawal V, Letai A, Lerou PH, Lahav G.

Cell Stem Cell. 2013 Oct 3;13(4):483-91. doi: 10.1016/j.stem.2013.07.018. Epub 2013 Aug 15. Erratum in: Cell Stem Cell. 2013 Nov 7;13(5):634. Agarwal, Vishesh [corrected to Agrawal, Vishesh].

17.

Use the duodenum, it’s right there: a retrospective cohort study comparing biliary reconstruction using either the jejunum or the duodenum.

Rose JB, Bilderback P, Raphaeli T, Traverso W, Helton S, Ryan JA Jr, Biehl T.

JAMA Surg. 2013 Sep;148(9):860-5.

PMID:
23884401
18.

Phosphorus concentration and loading reductions following changes in fertilizer application and formulation on managed turf.

King KW, Balogh JC, Agrawal SG, Tritabaugh CJ, Ryan JA.

J Environ Monit. 2012 Nov;14(11):2929-38. doi: 10.1039/c2em30213f.

PMID:
23026887
19.
20.

The effects of PTH, loading and surgical insult on cancellous bone at the bone-implant interface in the rabbit.

Fahlgren A, Yang X, Ciani C, Ryan JA, Kelly N, Ko FC, van der Meulen MC, Bostrom MP.

Bone. 2013 Feb;52(2):718-24. doi: 10.1016/j.bone.2012.05.005. Epub 2012 May 18.

21.

Pretreatment mitochondrial priming correlates with clinical response to cytotoxic chemotherapy.

Ni Chonghaile T, Sarosiek KA, Vo TT, Ryan JA, Tammareddi A, Moore Vdel G, Deng J, Anderson KC, Richardson P, Tai YT, Mitsiades CS, Matulonis UA, Drapkin R, Stone R, Deangelo DJ, McConkey DJ, Sallan SE, Silverman L, Hirsch MS, Carrasco DR, Letai A.

Science. 2011 Nov 25;334(6059):1129-33. doi: 10.1126/science.1206727. Epub 2011 Oct 27.

22.

Failure of the Patellar Tendon with the Patella Everted versus Noneverted in a Matched-Pair Cadaver Model.

Ryan JA, Meyers KN, Dibenedetto P, Wright TM, Haas SB.

HSS J. 2010 Sep;6(2):134-7. doi: 10.1007/s11420-009-9149-0. Epub 2010 Jan 29.

23.

The Bcl-2 repertoire of mesothelioma spheroids underlies acquired apoptotic multicellular resistance.

Barbone D, Ryan JA, Kolhatkar N, Chacko AD, Jablons DM, Sugarbaker DJ, Bueno R, Letai AG, Coussens LM, Fennell DA, Broaddus VC.

Cell Death Dis. 2011 Jun 23;2:e174. doi: 10.1038/cddis.2011.58.

24.

Virulence is context-dependent in a vertically transmitted aquatic host-microparasite system.

Ryan JA, Kohler SL.

Int J Parasitol. 2010 Dec;40(14):1665-73. doi: 10.1016/j.ijpara.2010.07.004. Epub 2010 Aug 8.

PMID:
20699101
25.

Heightened mitochondrial priming is the basis for apoptotic hypersensitivity of CD4+ CD8+ thymocytes.

Ryan JA, Brunelle JK, Letai A.

Proc Natl Acad Sci U S A. 2010 Jul 20;107(29):12895-900. doi: 10.1073/pnas.0914878107. Epub 2010 Jul 6.

26.

A comparison of low birth weight among newborns of early adolescents, late adolescents, and adult mothers in the Peruvian Amazon.

Ryan JA, Casapía M, Aguilar E, Silva H, Rahme E, Gagnon AJ, Manges AR, Joseph SA, Gyorkos TW.

Matern Child Health J. 2011 Jul;15(5):587-96. doi: 10.1007/s10995-010-0621-8.

PMID:
20535538
27.

Phytoavailability of cadmium in long-term biosolids-amended soils.

Kukier U, Chaney RL, Ryan JA, Daniels WL, Dowdy RH, Granato TC.

J Environ Qual. 2010 Feb 19;39(2):519-30. doi: 10.2134/jeq2007.0671. Print 2010 Mar-Apr.

PMID:
20176825
28.

Pantaloon hip spica cast and constrained liner for the treatment of early total hip dislocation in a young patient with sickle cell disease.

Meehan JP, Jamali AA, Ryan JA.

Am J Orthop (Belle Mead NJ). 2009 Dec;38(12):E184-6. Review. No abstract available.

PMID:
20145795
29.

Inadequate prenatal care and the risk of stillbirth in the Peruvian Amazon.

Gilbert NL, Casapía M, Joseph SA, Ryan JA, Gyorkos TW.

Int J Gynaecol Obstet. 2010 May;109(2):155-6. doi: 10.1016/j.ijgo.2009.12.009. Epub 2010 Jan 20. No abstract available.

PMID:
20089251
30.

Accuracy of computer navigation for acetabular component placement in THA.

Ryan JA, Jamali AA, Bargar WL.

Clin Orthop Relat Res. 2010 Jan;468(1):169-77. doi: 10.1007/s11999-009-1003-7. Epub 2009 Jul 24.

31.

Comparison of prenatal care coverage in early adolescents, late adolescents, and adult pregnant women in the Peruvian Amazon.

Ryan JA, Casapía M, Aguilar E, Silva H, Joseph SA, Gyorkos TW.

Int J Gynaecol Obstet. 2009 Nov;107(2):162-5. doi: 10.1016/j.ijgo.2009.06.014. Epub 2009 Jul 19.

PMID:
19619876
33.

Cellular uptake of gold nanoparticles passivated with BSA-SV40 large T antigen conjugates.

Ryan JA, Overton KW, Speight ME, Oldenburg CN, Loo L, Robarge W, Franzen S, Feldheim DL.

Anal Chem. 2007 Dec 1;79(23):9150-9. Epub 2007 Oct 31.

PMID:
17973401
34.

Doublecortin is expressed in articular chondrocytes.

Zhang Y, Ryan JA, Di Cesare PE, Liu J, Walsh CA, You Z.

Biochem Biophys Res Commun. 2007 Nov 23;363(3):694-700. Epub 2007 Sep 19.

PMID:
17897623
35.

Collaborative clinical quality improvement for pressure ulcers in nursing homes.

Lynn J, West J, Hausmann S, Gifford D, Nelson R, McGann P, Bergstrom N, Ryan JA.

J Am Geriatr Soc. 2007 Oct;55(10):1663-9. Epub 2007 Aug 21.

PMID:
17714457
36.

micro-XANES and micro-XRF investigations of metal binding mechanisms in biosolids.

Hettiarachchi GM, Scheckel KG, Ryan JA, Sutton SR, Newville M.

J Environ Qual. 2006 Jan 5;35(1):342-51. Print 2006 Jan-Feb.

PMID:
16397110
37.

Determining speciation of Pb in phosphate-amended soils: method limitations.

Scheckel KG, Ryan JA, Allen D, Lescano NV.

Sci Total Environ. 2005 Nov 1;350(1-3):261-72. Epub 2005 Apr 26.

PMID:
16227085
38.

Methods for speciation of metals in soils: a review.

D'Amore JJ, Al-Abed SR, Scheckel KG, Ryan JA.

J Environ Qual. 2005 Sep 8;34(5):1707-45. Print 2005 Sep-Oct. Review.

PMID:
16151225
39.
40.

One-gland exploration for mediastinal parathyroid adenomas: cervical and thoracoscopic approaches.

Liu RC, Hill ME, Ryan JA Jr.

Am J Surg. 2005 May;189(5):601-4; discussion 605.

PMID:
15862504
41.

An improved understanding of soil Cd risk to humans and low cost methods to phytoextract Cd from contaminated soils to prevent soil Cd risks.

Chaney RL, Reeves PG, Ryan JA, Simmons RW, Welch RM, Angle JS.

Biometals. 2004 Oct;17(5):549-53. Review.

PMID:
15688862
42.

Use of fish liver PLHC-1 cells and zebrafish embryos in cytotoxicity assays.

Krone PH, Blechinger SR, Evans TG, Ryan JA, Noonan EJ, Hightower LE.

Methods. 2005 Feb;35(2):176-87. Epub 2004 Dec 19.

PMID:
15649845
43.

Trace element chemistry in residual-treated soil: key concepts and metal bioavailability.

Basta NT, Ryan JA, Chaney RL.

J Environ Qual. 2005 Jan-Feb;34(1):49-63. Review.

PMID:
15647534
44.

Maximizing outcomes while minimizing exploration in hyperparathyroidism using localization tests.

Ryan JA Jr, Lee FT.

Arch Surg. 2004 Aug;139(8):838-42; discussion 842-3.

PMID:
15302692
45.

Spectroscopic speciation and quantification of lead in phosphate-amended soils.

Scheckel KG, Ryan JA.

J Environ Qual. 2004 Jul-Aug;33(4):1288-95.

PMID:
15254110
46.

Lead sorption on ruthenium oxide: a macroscopic and spectroscopic study.

Scheckel KG, Impellitteri CA, Ryan JA.

Environ Sci Technol. 2004 May 15;38(10):2836-42.

PMID:
15212257
47.

Outcomes after resection of cholangiocellular carcinoma.

Huang JL, Biehl TR, Lee FT, Zimmer PW, Ryan JA Jr.

Am J Surg. 2004 May;187(5):612-7.

PMID:
15135676
48.

Outcome of gastrocnemius recession and tendo-achilles lengthening in ambulatory children with cerebral palsy.

Kay RM, Rethlefsen SA, Ryan JA, Wren TA.

J Pediatr Orthop B. 2004 Mar;13(2):92-8.

PMID:
15076586
49.

In situ soil treatments to reduce the phyto- and bioavailability of lead, zinc, and cadmium.

Brown S, Chaney R, Hallfrisch J, Ryan JA, Berti WR.

J Environ Qual. 2004 Mar-Apr;33(2):522-31.

PMID:
15074803
50.

Reducing children's risk from lead in soil.

Ryan JA, Scheckel KG, Berti WR, Brown SL, Casteel SW, Chaney RL, Hallfrisch J, Doolan M, Grevatt P, Maddaloni M, Mosby D.

Environ Sci Technol. 2004 Jan 1;38(1):18A-24A. Review. No abstract available.

PMID:
14740710

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