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Items: 23

1.

hPSC Modeling Reveals that Fate Selection of Cortical Deep Projection Neurons Occurs in the Subplate.

Ozair MZ, Kirst C, van den Berg BL, Ruzo A, Rito T, Brivanlou AH.

Cell Stem Cell. 2018 Jul 5;23(1):60-73.e6. doi: 10.1016/j.stem.2018.05.024. Epub 2018 Jun 21.

PMID:
29937203
2.

Self-organization of a human organizer by combined Wnt and Nodal signalling.

Martyn I, Kanno TY, Ruzo A, Siggia ED, Brivanlou AH.

Nature. 2018 Jun;558(7708):132-135. doi: 10.1038/s41586-018-0150-y. Epub 2018 May 23.

PMID:
29795348
3.

Chromosomal instability during neurogenesis in Huntington's disease.

Ruzo A, Croft GF, Metzger JJ, Galgoczi S, Gerber LJ, Pellegrini C, Wang H Jr, Fenner M, Tse S, Marks A, Nchako C, Brivanlou AH.

Development. 2018 Jan 29;145(2). pii: dev156844. doi: 10.1242/dev.156844.

PMID:
29378824
4.

At Last: Gene Editing in Human Embryos to Understand Human Development.

Ruzo A, Brivanlou AH.

Cell Stem Cell. 2017 Nov 2;21(5):564-565. doi: 10.1016/j.stem.2017.10.008.

PMID:
29100008
5.

Morphogen and community effects determine cell fates in response to BMP4 signaling in human embryonic stem cells.

Nemashkalo A, Ruzo A, Heemskerk I, Warmflash A.

Development. 2017 Sep 1;144(17):3042-3053. doi: 10.1242/dev.153239. Epub 2017 Jul 31.

6.

Inhibition of Cell Division and DNA Replication Impair Mouse-Naïve Pluripotency Exit.

Waisman A, Vazquez Echegaray C, Solari C, Cosentino MS, Martyn I, Deglincerti A, Ozair MZ, Ruzo A, Barañao L, Miriuka S, Brivanlou A, Guberman A.

J Mol Biol. 2017 Sep 1;429(18):2802-2815. doi: 10.1016/j.jmb.2017.06.020. Epub 2017 Jul 3.

PMID:
28684247
7.

SAMHD1 is active in cycling cells permissive to HIV-1 infection.

Badia R, Pujantell M, Torres-Torronteras J, Menéndez-Arias L, Martí R, Ruzo A, Pauls E, Clotet B, Ballana E, Esté JA, Riveira-Muñoz E.

Antiviral Res. 2017 Jun;142:123-135. doi: 10.1016/j.antiviral.2017.03.019. Epub 2017 Mar 28.

PMID:
28359840
8.

A Balance between Secreted Inhibitors and Edge Sensing Controls Gastruloid Self-Organization.

Etoc F, Metzger J, Ruzo A, Kirst C, Yoney A, Ozair MZ, Brivanlou AH, Siggia ED.

Dev Cell. 2016 Nov 7;39(3):302-315. doi: 10.1016/j.devcel.2016.09.016. Epub 2016 Oct 13.

9.

Self-organization of human embryonic stem cells on micropatterns.

Deglincerti A, Etoc F, Guerra MC, Martyn I, Metzger J, Ruzo A, Simunovic M, Yoney A, Brivanlou AH, Siggia E, Warmflash A.

Nat Protoc. 2016 Nov;11(11):2223-2232. doi: 10.1038/nprot.2016.131. Epub 2016 Oct 13.

10.

GFP-specific CD8 T cells enable targeted cell depletion and visualization of T-cell interactions.

Agudo J, Ruzo A, Park ES, Sweeney R, Kana V, Wu M, Zhao Y, Egli D, Merad M, Brown BD.

Nat Biotechnol. 2015 Dec;33(12):1287-1292. doi: 10.1038/nbt.3386. Epub 2015 Nov 2.

11.

Discovery of novel isoforms of huntingtin reveals a new hominid-specific exon.

Ruzo A, Ismailoglu I, Popowski M, Haremaki T, Croft GF, Deglincerti A, Brivanlou AH.

PLoS One. 2015 May 26;10(5):e0127687. doi: 10.1371/journal.pone.0127687. eCollection 2015.

12.

BRAF-V600E expression in precursor versus differentiated dendritic cells defines clinically distinct LCH risk groups.

Berres ML, Lim KP, Peters T, Price J, Takizawa H, Salmon H, Idoyaga J, Ruzo A, Lupo PJ, Hicks MJ, Shih A, Simko SJ, Abhyankar H, Chakraborty R, Leboeuf M, Beltrão M, Lira SA, Heym KM, Clausen BE, Bigley V, Collin M, Manz MG, McClain K, Merad M, Allen CE.

J Exp Med. 2015 Feb 9;212(2):281. doi: 10.1084/jem.2013097701202015c. Epub 2015 Feb 2. No abstract available.

13.

BRAF-V600E expression in precursor versus differentiated dendritic cells defines clinically distinct LCH risk groups.

Berres ML, Lim KP, Peters T, Price J, Takizawa H, Salmon H, Idoyaga J, Ruzo A, Lupo PJ, Hicks MJ, Shih A, Simko SJ, Abhyankar H, Chakraborty R, Leboeuf M, Beltrão M, Lira SA, Heym KM, Bigley V, Collin M, Manz MG, McClain K, Merad M, Allen CE.

J Exp Med. 2014 Apr 7;211(4):669-83. doi: 10.1084/jem.20130977. Epub 2014 Mar 17. Erratum in: J Exp Med. 2015 Feb 9;212(2):281.

14.

The miR-126-VEGFR2 axis controls the innate response to pathogen-associated nucleic acids.

Agudo J, Ruzo A, Tung N, Salmon H, Leboeuf M, Hashimoto D, Becker C, Garrett-Sinha LA, Baccarini A, Merad M, Brown BD.

Nat Immunol. 2014 Jan;15(1):54-62. doi: 10.1038/ni.2767. Epub 2013 Nov 24.

15.

Whole body correction of mucopolysaccharidosis IIIA by intracerebrospinal fluid gene therapy.

Haurigot V, Marcó S, Ribera A, Garcia M, Ruzo A, Villacampa P, Ayuso E, Añor S, Andaluz A, Pineda M, García-Fructuoso G, Molas M, Maggioni L, Muñoz S, Motas S, Ruberte J, Mingozzi F, Pumarola M, Bosch F.

J Clin Invest. 2013 Jul 1. pii: 66778. doi: 10.1172/JCI66778. [Epub ahead of print]

16.

Nonviral-mediated hepatic expression of IGF-I increases Treg levels and suppresses autoimmune diabetes in mice.

Anguela XM, Tafuro S, Roca C, Callejas D, Agudo J, Obach M, Ribera A, Ruzo A, Mann CJ, Casellas A, Bosch F.

Diabetes. 2013 Feb;62(2):551-60. doi: 10.2337/db11-1776. Epub 2012 Oct 25.

17.

Vascular endothelial growth factor-mediated islet hypervascularization and inflammation contribute to progressive reduction of β-cell mass.

Agudo J, Ayuso E, Jimenez V, Casellas A, Mallol C, Salavert A, Tafuro S, Obach M, Ruzo A, Moya M, Pujol A, Bosch F.

Diabetes. 2012 Nov;61(11):2851-61. doi: 10.2337/db12-0134. Epub 2012 Sep 6.

18.

Correction of pathological accumulation of glycosaminoglycans in central nervous system and peripheral tissues of MPSIIIA mice through systemic AAV9 gene transfer.

Ruzo A, Marcó S, García M, Villacampa P, Ribera A, Ayuso E, Maggioni L, Mingozzi F, Haurigot V, Bosch F.

Hum Gene Ther. 2012 Dec;23(12):1237-46. doi: 10.1089/hum.2012.029. Epub 2012 Oct 17.

PMID:
22909060
19.

A TLR and non-TLR mediated innate response to lentiviruses restricts hepatocyte entry and can be ameliorated by pharmacological blockade.

Agudo J, Ruzo A, Kitur K, Sachidanandam R, Blander JM, Brown BD.

Mol Ther. 2012 Dec;20(12):2257-67. doi: 10.1038/mt.2012.150. Epub 2012 Aug 7.

20.

High-throughput assessment of microRNA activity and function using microRNA sensor and decoy libraries.

Mullokandov G, Baccarini A, Ruzo A, Jayaprakash AD, Tung N, Israelow B, Evans MJ, Sachidanandam R, Brown BD.

Nat Methods. 2012 Jul 1;9(8):840-6. doi: 10.1038/nmeth.2078.

21.

Molecular signature of the immune and tissue response to non-coding plasmid DNA in skeletal muscle after electrotransfer.

Mann CJ, Anguela XM, Montané J, Obach M, Roca C, Ruzo A, Otaegui P, Mir LM, Bosch F.

Gene Ther. 2012 Dec;19(12):1177-86. doi: 10.1038/gt.2011.198. Epub 2011 Dec 15.

PMID:
22170344
22.

Liver production of sulfamidase reverses peripheral and ameliorates CNS pathology in mucopolysaccharidosis IIIA mice.

Ruzo A, Garcia M, Ribera A, Villacampa P, Haurigot V, Marcó S, Ayuso E, Anguela XM, Roca C, Agudo J, Ramos D, Ruberte J, Bosch F.

Mol Ther. 2012 Feb;20(2):254-66. doi: 10.1038/mt.2011.220. Epub 2011 Oct 18.

23.

Phosphofructo-1-kinase deficiency leads to a severe cardiac and hematological disorder in addition to skeletal muscle glycogenosis.

García M, Pujol A, Ruzo A, Riu E, Ruberte J, Arbós A, Serafín A, Albella B, Felíu JE, Bosch F.

PLoS Genet. 2009 Aug;5(8):e1000615. doi: 10.1371/journal.pgen.1000615. Epub 2009 Aug 21.

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