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Method comparison study of the Elecsys® β-Amyloid (1-42) CSF assay versus comparator assays and LC-MS/MS.

Shaw LM, Hansson O, Manuilova E, Masters CL, Doecke JD, Li QX, Rutz S, Widmann M, Leinenbach A, Blennow K.

Clin Biochem. 2019 May 23. pii: S0009-9120(19)30488-6. doi: 10.1016/j.clinbiochem.2019.05.006. [Epub ahead of print]


Coexpression of Inhibitory Receptors Enriches for Activated and Functional CD8+ T Cells in Murine Syngeneic Tumor Models.

Xiong H, Mittman S, Rodriguez R, Pacheco-Sanchez P, Moskalenko M, Yang Y, Elstrott J, Ritter AT, Müller S, Nickles D, Arenzana TL, Capietto AH, Delamarre L, Modrusan Z, Rutz S, Mellman I, Cubas R.

Cancer Immunol Res. 2019 Jun;7(6):963-976. doi: 10.1158/2326-6066.CIR-18-0750. Epub 2019 May 7.


c-Maf-dependent Treg cell control of intestinal TH17 cells and IgA establishes host-microbiota homeostasis.

Neumann C, Blume J, Roy U, Teh PP, Vasanthakumar A, Beller A, Liao Y, Heinrich F, Arenzana TL, Hackney JA, Eidenschenk C, Gálvez EJC, Stehle C, Heinz GA, Maschmeyer P, Sidwell T, Hu Y, Amsen D, Romagnani C, Chang HD, Kruglov A, Mashreghi MF, Shi W, Strowig T, Rutz S, Kallies A, Scheffold A.

Nat Immunol. 2019 Apr;20(4):471-481. doi: 10.1038/s41590-019-0316-2. Epub 2019 Feb 18.


Ribonucleoprotein Transfection for CRISPR/Cas9-Mediated Gene Knockout in Primary T Cells.

Oh SA, Seki A, Rutz S.

Curr Protoc Immunol. 2019 Feb;124(1):e69. doi: 10.1002/cpim.69. Epub 2018 Oct 18.


Commutability of the certified reference materials for the standardization of β-amyloid 1-42 assay in human cerebrospinal fluid: lessons for tau and β-amyloid 1-40 measurements.

Andreasson U, Kuhlmann J, Pannee J, Umek RM, Stoops E, Vanderstichele H, Matzen A, Vandijck M, Dauwe M, Leinenbach A, Rutz S, Portelius E, Zegers I, Zetterberg H, Blennow K.

Clin Chem Lab Med. 2018 Nov 27;56(12):2058-2066. doi: 10.1515/cclm-2018-0147.


The impact of preanalytical variables on measuring cerebrospinal fluid biomarkers for Alzheimer's disease diagnosis: A review.

Hansson O, Mikulskis A, Fagan AM, Teunissen C, Zetterberg H, Vanderstichele H, Molinuevo JL, Shaw LM, Vandijck M, Verbeek MM, Savage M, Mattsson N, Lewczuk P, Batrla R, Rutz S, Dean RA, Blennow K.

Alzheimers Dement. 2018 Oct;14(10):1313-1333. doi: 10.1016/j.jalz.2018.05.008. Epub 2018 Jun 23. Review.


Cdc48-like protein of actinobacteria (Cpa) is a novel proteasome interactor in mycobacteria and related organisms.

Ziemski M, Jomaa A, Mayer D, Rutz S, Giese C, Veprintsev D, Weber-Ban E.

Elife. 2018 May 29;7. pii: e34055. doi: 10.7554/eLife.34055.


Technical and clinical performance of a new assay to detect squamous cell carcinoma antigen levels for the differential diagnosis of cervical, lung, and head and neck cancer.

Holdenrieder S, Molina R, Qiu L, Zhi X, Rutz S, Engel C, Kasper-Sauer P, Dayyani F, Korse CM.

Tumour Biol. 2018 Apr;40(4):1010428318772202. doi: 10.1177/1010428318772202.


Tumor suppressor BAP1 is essential for thymic development and proliferative responses of T lymphocytes.

Arenzana TL, Lianoglou S, Seki A, Eidenschenk C, Cheung T, Seshasayee D, Hagenbeek T, Sambandam A, Noubade R, Peng I, Lesch J, DeVoss J, Wu X, Lee WP, Caplazi P, Webster J, Liu J, Pham VC, Arnott D, Lill JR, Modrusan Z, Dey A, Rutz S.

Sci Immunol. 2018 Apr 20;3(22). pii: eaal1953. doi: 10.1126/sciimmunol.aal1953.


Inspectors' responses to adolescents' assessment of quality of care: a case study on involving adolescents in inspections.

Rutz S, van de Bovenkamp H, Buitendijk S, Robben P, de Bont A.

BMC Health Serv Res. 2018 Apr 2;18(1):226. doi: 10.1186/s12913-018-2998-9.


Optimized RNP transfection for highly efficient CRISPR/Cas9-mediated gene knockout in primary T cells.

Seki A, Rutz S.

J Exp Med. 2018 Mar 5;215(3):985-997. doi: 10.1084/jem.20171626. Epub 2018 Feb 7.


Targeting IL-10 Family Cytokines for the Treatment of Human Diseases.

Wang X, Wong K, Ouyang W, Rutz S.

Cold Spring Harb Perspect Biol. 2019 Feb 1;11(2). pii: a028548. doi: 10.1101/cshperspect.a028548. Review.


Regulation of Interleukin-10 Expression.

Rutz S, Ouyang W.

Adv Exp Med Biol. 2016;941:89-116. Review.


Post-translational regulation of RORγt-A therapeutic target for the modulation of interleukin-17-mediated responses in autoimmune diseases.

Rutz S, Eidenschenk C, Kiefer JR, Ouyang W.

Cytokine Growth Factor Rev. 2016 Aug;30:1-17. doi: 10.1016/j.cytogfr.2016.07.004. Epub 2016 Jul 25. Review.


Body Image Perception in Acromegaly Is Not Associated with Objective Acromegalic Changes but Depends on Depressive Symptoms.

Dimopoulou C, Leistner SM, Ising M, Schneider HJ, Schopohl J, Rutz S, Kosilek R, Frohner R, Stalla GK, Sievers C.

Neuroendocrinology. 2017;105(2):115-122. doi: 10.1159/000448519. Epub 2016 Jul 25.


The Itch to degrade ROR-γt.

Rutz S, Ouyang W.

Nat Immunol. 2016 Jul 19;17(8):898-900. doi: 10.1038/ni.3516. No abstract available.


Comparison of Plasma and Urine Biomarker Performance in Acute Kidney Injury.

Schley G, Köberle C, Manuilova E, Rutz S, Forster C, Weyand M, Formentini I, Kientsch-Engel R, Eckardt KU, Willam C.

PLoS One. 2015 Dec 15;10(12):e0145042. doi: 10.1371/journal.pone.0145042. eCollection 2015.


Interleukin-22 induces interleukin-18 expression from epithelial cells during intestinal infection.

Muñoz M, Eidenschenk C, Ota N, Wong K, Lohmann U, Kühl AA, Wang X, Manzanillo P, Li Y, Rutz S, Zheng Y, Diehl L, Kayagaki N, van Lookeren-Campagne M, Liesenfeld O, Heimesaat M, Ouyang W.

Immunity. 2015 Feb 17;42(2):321-331. doi: 10.1016/j.immuni.2015.01.011. Epub 2015 Feb 10.


Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells.

Rutz S, Kayagaki N, Phung QT, Eidenschenk C, Noubade R, Wang X, Lesch J, Lu R, Newton K, Huang OW, Cochran AG, Vasser M, Fauber BP, DeVoss J, Webster J, Diehl L, Modrusan Z, Kirkpatrick DS, Lill JR, Ouyang W, Dixit VM.

Nature. 2015 Feb 19;518(7539):417-21. doi: 10.1038/nature13979. Epub 2014 Dec 3.


The IL-20 subfamily of cytokines--from host defence to tissue homeostasis.

Rutz S, Wang X, Ouyang W.

Nat Rev Immunol. 2014 Dec;14(12):783-95. doi: 10.1038/nri3766. Review.


Costs and Effectiveness of Combination Therapy with Bedaquiline and other Anti-Tuberculosis Drugs in Patients with Multi- and Extensively Drug-Resistant Tuberculosis in Germany.

Wolfson L, Wirth D, Jibbert J, Diel R, Rutz S.

Value Health. 2014 Nov;17(7):A674-5. doi: 10.1016/j.jval.2014.08.2503. Epub 2014 Oct 26. No abstract available.


Role of Blimp-1 in programing Th effector cells into IL-10 producers.

Neumann C, Heinrich F, Neumann K, Junghans V, Mashreghi MF, Ahlers J, Janke M, Rudolph C, Mockel-Tenbrinck N, Kühl AA, Heimesaat MM, Esser C, Im SH, Radbruch A, Rutz S, Scheffold A.

J Exp Med. 2014 Aug 25;211(9):1807-19. doi: 10.1084/jem.20131548. Epub 2014 Jul 29.


Role of IL-22 in microbial host defense.

Eidenschenk C, Rutz S, Liesenfeld O, Ouyang W.

Curr Top Microbiol Immunol. 2014;380:213-36. doi: 10.1007/978-3-662-43492-5_10. Review.


NRROS negatively regulates reactive oxygen species during host defence and autoimmunity.

Noubade R, Wong K, Ota N, Rutz S, Eidenschenk C, Valdez PA, Ding J, Peng I, Sebrell A, Caplazi P, DeVoss J, Soriano RH, Sai T, Lu R, Modrusan Z, Hackney J, Ouyang W.

Nature. 2014 May 8;509(7499):235-9. doi: 10.1038/nature13152. Epub 2014 Apr 13.


NGAL, L-FABP, and KIM-1 in comparison to established markers of renal dysfunction.

Holzscheiter L, Beck C, Rutz S, Manuilova E, Domke I, Guder WG, Hofmann W.

Clin Chem Lab Med. 2014 Apr;52(4):537-46. doi: 10.1515/cclm-2013-0693.


IL-22, not simply a Th17 cytokine.

Rutz S, Eidenschenk C, Ouyang W.

Immunol Rev. 2013 Mar;252(1):116-32. doi: 10.1111/imr.12027. Review.


A genomic regulatory element that directs assembly and function of immune-specific AP-1-IRF complexes.

Glasmacher E, Agrawal S, Chang AB, Murphy TL, Zeng W, Vander Lugt B, Khan AA, Ciofani M, Spooner CJ, Rutz S, Hackney J, Nurieva R, Escalante CR, Ouyang W, Littman DR, Murphy KM, Singh H.

Science. 2012 Nov 16;338(6109):975-80. doi: 10.1126/science.1228309. Epub 2012 Sep 13.


Regulation of epithelial immunity by IL-17 family cytokines.

Pappu R, Rutz S, Ouyang W.

Trends Immunol. 2012 Jul;33(7):343-9. doi: 10.1016/ Epub 2012 Apr 2. Review.


Tuberculosis: cost of illness in Germany.

Diel R, Rutz S, Castell S, Schaberg T.

Eur Respir J. 2012 Jul;40(1):143-51. doi: 10.1183/09031936.00204611. Epub 2012 Jan 20.


Transcription factor c-Maf mediates the TGF-β-dependent suppression of IL-22 production in T(H)17 cells.

Rutz S, Noubade R, Eidenschenk C, Ota N, Zeng W, Zheng Y, Hackney J, Ding J, Singh H, Ouyang W.

Nat Immunol. 2011 Oct 16;12(12):1238-45. doi: 10.1038/ni.2134.


Regulation of interleukin-10 and interleukin-22 expression in T helper cells.

Rutz S, Ouyang W.

Curr Opin Immunol. 2011 Oct;23(5):605-12. doi: 10.1016/j.coi.2011.07.018. Epub 2011 Aug 20. Review.


Reprogrammed quiescent B cells provide an effective cellular therapy against chronic experimental autoimmune encephalomyelitis.

Calderón-Gómez E, Lampropoulou V, Shen P, Neves P, Roch T, Stervbo U, Rutz S, Kühl AA, Heppner FL, Loddenkemper C, Anderton SM, Kanellopoulos JM, Charneau P, Fillatreau S.

Eur J Immunol. 2011 Jun;41(6):1696-708. doi: 10.1002/eji.201041041. Epub 2011 May 25.


Regulation and functions of the IL-10 family of cytokines in inflammation and disease.

Ouyang W, Rutz S, Crellin NK, Valdez PA, Hymowitz SG.

Annu Rev Immunol. 2011;29:71-109. doi: 10.1146/annurev-immunol-031210-101312. Review.


Differences in school environment, school policy and actions regarding overweight prevention between Dutch schools. A nationwide survey.

Scholtens S, Middelbeek L, Rutz SI, Buijs G, Bemelmans WJ.

BMC Public Health. 2010 Jan 28;10:42. doi: 10.1186/1471-2458-10-42.


Cutting edge: Plasmacytoid dendritic cells induce IL-10 production in T cells via the Delta-like-4/Notch axis.

Kassner N, Krueger M, Yagita H, Dzionek A, Hutloff A, Kroczek R, Scheffold A, Rutz S.

J Immunol. 2010 Jan 15;184(2):550-4. doi: 10.4049/jimmunol.0903152. Epub 2009 Dec 11.


siRNA stabilization prolongs gene knockdown in primary T lymphocytes.

Mantei A, Rutz S, Janke M, Kirchhoff D, Jung U, Patzel V, Vogel U, Rudel T, Andreou I, Weber M, Scheffold A.

Eur J Immunol. 2008 Sep;38(9):2616-25. doi: 10.1002/eji.200738075.


[Self-limitation of inflammatory T-cell responses. Help to self-help as a therapeutic concept].

Rutz S, Scheffold A.

Z Rheumatol. 2008 Oct;67(6):500-2. doi: 10.1007/s00393-008-0343-0. German.


Autoregulation of Th1-mediated inflammation by twist1.

Niesner U, Albrecht I, Janke M, Doebis C, Loddenkemper C, Lexberg MH, Eulenburg K, Kreher S, Koeck J, Baumgrass R, Bonhagen K, Kamradt T, Enghard P, Humrich JY, Rutz S, Schulze-Topphoff U, Aktas O, Bartfeld S, Radbruch H, Hegazy AN, Löhning M, Baumgart DC, Duchmann R, Rudwaleit M, Häupl T, Gitelman I, Krenn V, Gruen J, Sieper J, Zeitz M, Wiedenmann B, Zipp F, Hamann A, Janitz M, Scheffold A, Burmester GR, Chang HD, Radbruch A.

J Exp Med. 2008 Aug 4;205(8):1889-901. doi: 10.1084/jem.20072468. Epub 2008 Jul 28.


Notch regulates IL-10 production by T helper 1 cells.

Rutz S, Janke M, Kassner N, Hohnstein T, Krueger M, Scheffold A.

Proc Natl Acad Sci U S A. 2008 Mar 4;105(9):3497-502. doi: 10.1073/pnas.0712102105. Epub 2008 Feb 21.


Effects of ethanol and 3,4-methylenedioxymethamphetamine (MDMA) alone or in combination on spontaneous and evoked overflow of dopamine, serotonin and acetylcholine in striatal slices of the rat brain.

Riegert C, Wedekind F, Hamida SB, Rutz S, Rothmaier AK, Jones BC, Cassel JC, Jackisch R.

Int J Neuropsychopharmacol. 2008 Sep;11(6):743-63. doi: 10.1017/S1461145708008481. Epub 2008 Feb 4.


The modulation of striatal dopamine release correlates with water-maze performance in aged rats.

Rutz S, Majchrzak M, Siedschlag V, Barbelivien A, Harati H, Rothmaier AK, Feuerstein TJ, Jackisch R, Cassel JC.

Neurobiol Aging. 2009 Jun;30(6):957-72. Epub 2007 Nov 7.


Agonist-mediated regulation of presynaptic receptor function during development of rat septal neurons in culture.

Ehret A, Birthelmer A, Rutz S, Riegert C, Rothmaier AK, Jackisch R.

J Neurochem. 2007 Aug;102(4):1071-82. Epub 2007 Apr 30.


Presynaptic modulation of 5-HT release in the rat septal region.

Rutz S, Riegert C, Rothmaier AK, Jackisch R.

Neuroscience. 2007 May 11;146(2):643-58. Epub 2007 Mar 23.


Presynaptic serotonergic modulation of 5-HT and acetylcholine release in the hippocampus and the cortex of 5-HT1B-receptor knockout mice.

Rutz S, Riegert C, Rothmaier AK, Buhot MC, Cassel JC, Jackisch R.

Brain Res Bull. 2006 Jun 15;70(1):81-93. Epub 2006 May 3.


Maturation and maintenance of cholinergic medial septum neurons require glucocorticoid receptor signaling.

Guijarro C, Rutz S, Rothmaier K, Turiault M, Zhi Q, Naumann T, Frotscher M, Tronche F, Jackisch R, Kretz O.

J Neurochem. 2006 May;97(3):747-58. Epub 2006 Mar 29.


Design of siRNAs producing unstructured guide-RNAs results in improved RNA interference efficiency.

Patzel V, Rutz S, Dietrich I, Köberle C, Scheffold A, Kaufmann SH.

Nat Biotechnol. 2005 Nov;23(11):1440-4. Epub 2005 Oct 30.


Notch ligands Delta-like1, Delta-like4 and Jagged1 differentially regulate activation of peripheral T helper cells.

Rutz S, Mordmüller B, Sakano S, Scheffold A.

Eur J Immunol. 2005 Aug;35(8):2443-51.


Ethanol, 3,4-methylenedioxymethamphetamine (ecstasy) and their combination: long-term behavioral, neurochemical and neuropharmacological effects in the rat.

Cassel JC, Riegert C, Rutz S, Koenig J, Rothmaier K, Cosquer B, Lazarus C, Birthelmer A, Jeltsch H, Jones BC, Jackisch R.

Neuropsychopharmacology. 2005 Oct;30(10):1870-82.


Interleukin-2 is essential for CD4+CD25+ regulatory T cell function.

de la Rosa M, Rutz S, Dorninger H, Scheffold A.

Eur J Immunol. 2004 Sep;34(9):2480-8.


Towards in vivo application of RNA interference - new toys, old problems.

Rutz S, Scheffold A.

Arthritis Res Ther. 2004;6(2):78-85. Epub 2004 Mar 10.

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