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Items: 1 to 50 of 306

1.

US immigration order strikes against biotech.

Levin JM, Holtzman SH, Maraganore J, Hastings PJ, Cohen R, Dahiyat B, Adams J, Adams C, Ahrens B, Albers J, Aspinall MG, Audia JE, Babler M, Barrett P, Barry Z, Bermingham N, Bloch S, Blum RI, Bolno PB, Bonney MW, Booth B, Bradbury DM, Brauer SK, Byers B, Cagnoni PJ, Cali BM, Ciechanover I, Clark C, Clayman MD, Cleland JL, Cobb P, Cooper R, Currie MG, Diekman J, Dobmeier EL, Doerfler D, Donley EL, Dunsire D, During M, Eckstein JW, Elenko E, Exter NA, Fleming JJ, Flesher GJ, Formela JF, Forrester R, Francois C, Franklin H, Freeman MW, Furst H, Gage LP, Galakatos N, Gallagher BM, Geraghty JA, Gill S, Goeddel DV, Goldsmith MA, Gowen M, Goyal V, Graney T, Grayzel D, Greene B, Grint P, Gutierrez-Ramos JC, Haney B, Ha-Ngoc T, Harris T, Hasnain F, Hata YS, Hecht P, Henshaw L, Heyman R, Hoppenot H, Horvitz HR, Hughes TE, Hutton WS, Isaacs ST, Jenkins A, Jonker J, Kaplan J, Karsen P, Keiper J, Kim J, Kindler J, King R, King V, Kjellson N, Koenig S, Koenig G, Kolchinsky P, Laikind P, Langer RB, Lee JJ, Leff JS, Leicher BA, Leschly N, Levin A, Levin M, Levine AJ, Levy A, Liu DR, Lodish HF, Lopatin U, Love TW, Macdonald G, Maderis GJ, Mahadevia A, Mahanthappa NK, Martin JF, Martin A, Martucci WE, McArthur JG, McCann CM, McCarthy SA, McDonough CG, Mendlein J, Miller L, Miralles D, Moch KI, More B, Myers AG, Narachi MA, Nashat A, Nelson W, Newell WJ, Olle B, Osborn JE, Owens JC, Pande A, Papadopoulos S, Parker HS, Parmar KM, Patterson MR, Paul SM, Perez R, Perry M, Pfeffer CG, Powell M, Pruzanski M, Purcell DJ, Rakhit A, Ramamoorthi K, Rastetter W, Rawcliffe AA, Reid LE, Renaud RC, Rhodes JP, Rieflin WJ, Robins C, Rocklage SM, Rosenblatt M, Rosin JG, Rutter WJ, Saha S, Samuels C, Sato VL, Scangos G, Scarlett JA, Schenkein D, Schreiber SL, Schwab A, Sekhri P, Shah R, Shenk T, Siegall CB, Simon NJ, Simonian N, Stein J, Su M, Szela MT, Taglietti M, Tandon N, Termeer H, Thornberry NA, Tolar M, Ulevitch R, Vaishnaw AK, VanLent A, Varsavsky M, Vlasuk GP, Vounatsos M, Waksal SG, Warma N, Watts RJ, Werber Y, Westphal C, Wierenga W, Williams DE, Williams LR, Xanthopoulos KG, Zohar D, Zweifach SS.

Nat Biotechnol. 2017 Mar 7;35(3):204-206. doi: 10.1038/nbt.3824. No abstract available.

PMID:
28267733
2.

Climate change and the integrity of science.

Gleick PH, Adams RM, Amasino RM, Anders E, Anderson DJ, Anderson WW, Anselin LE, Arroyo MK, Asfaw B, Ayala FJ, Bax A, Bebbington AJ, Bell G, Bennett MV, Bennetzen JL, Berenbaum MR, Berlin OB, Bjorkman PJ, Blackburn E, Blamont JE, Botchan MR, Boyer JS, Boyle EA, Branton D, Briggs SP, Briggs WR, Brill WJ, Britten RJ, Broecker WS, Brown JH, Brown PO, Brunger AT, Cairns J Jr, Canfield DE, Carpenter SR, Carrington JC, Cashmore AR, Castilla JC, Cazenave A, Chapin FS 3rd, Ciechanover AJ, Clapham DE, Clark WC, Clayton RN, Coe MD, Conwell EM, Cowling EB, Cowling RM, Cox CS, Croteau RB, Crothers DM, Crutzen PJ, Daily GC, Dalrymple GB, Dangl JL, Darst SA, Davies DR, Davis MB, De Camilli PV, Dean C, DeFries RS, Deisenhofer J, Delmer DP, DeLong EF, DeRosier DJ, Diener TO, Dirzo R, Dixon JE, Donoghue MJ, Doolittle RF, Dunne T, Ehrlich PR, Eisenstadt SN, Eisner T, Emanuel KA, Englander SW, Ernst WG, Falkowski PG, Feher G, Ferejohn JA, Fersht A, Fischer EH, Fischer R, Flannery KV, Frank J, Frey PA, Fridovich I, Frieden C, Futuyma DJ, Gardner WR, Garrett CJ, Gilbert W, Goldberg RB, Goodenough WH, Goodman CS, Goodman M, Greengard P, Hake S, Hammel G, Hanson S, Harrison SC, Hart SR, Hartl DL, Haselkorn R, Hawkes K, Hayes JM, Hille B, Hökfelt T, House JS, Hout M, Hunten DM, Izquierdo IA, Jagendorf AT, Janzen DH, Jeanloz R, Jencks CS, Jury WA, Kaback HR, Kailath T, Kay P, Kay SA, Kennedy D, Kerr A, Kessler RC, Khush GS, Kieffer SW, Kirch PV, Kirk K, Kivelson MG, Klinman JP, Klug A, Knopoff L, Kornberg H, Kutzbach JE, Lagarias JC, Lambeck K, Landy A, Langmuir CH, Larkins BA, Le Pichon XT, Lenski RE, Leopold EB, Levin SA, Levitt M, Likens GE, Lippincott-Schwartz J, Lorand L, Lovejoy CO, Lynch M, Mabogunje AL, Malone TF, Manabe S, Marcus J, Massey DS, McWilliams JC, Medina E, Melosh HJ, Meltzer DJ, Michener CD, Miles EL, Mooney HA, Moore PB, Morel FM, Mosley-Thompson ES, Moss B, Munk WH, Myers N, Nair GB, Nathans J, Nester EW, Nicoll RA, Novick RP, O'Connell JF, Olsen PE, Opdyke ND, Oster GF, Ostrom E, Pace NR, Paine RT, Palmiter RD, Pedlosky J, Petsko GA, Pettengill GH, Philander SG, Piperno DR, Pollard TD, Price PB Jr, Reichard PA, Reskin BF, Ricklefs RE, Rivest RL, Roberts JD, Romney AK, Rossmann MG, Russell DW, Rutter WJ, Sabloff JA, Sagdeev RZ, Sahlins MD, Salmond A, Sanes JR, Schekman R, Schellnhuber J, Schindler DW, Schmitt J, Schneider SH, Schramm VL, Sederoff RR, Shatz CJ, Sherman F, Sidman RL, Sieh K, Simons EL, Singer BH, Singer MF, Skyrms B, Sleep NH, Smith BD, Snyder SH, Sokal RR, Spencer CS, Steitz TA, Strier KB, Südhof TC, Taylor SS, Terborgh J, Thomas DH, Thompson LG, Tjian RT, Turner MG, Uyeda S, Valentine JW, Valentine JS, Van Etten JL, van Holde KE, Vaughan M, Verba S, von Hippel PH, Wake DB, Walker A, Walker JE, Watson EB, Watson PJ, Weigel D, Wessler SR, West-Eberhard MJ, White TD, Wilson WJ, Wolfenden RV, Wood JA, Woodwell GM, Wright HE Jr, Wu C, Wunsch C, Zoback ML.

Science. 2010 May 7;328(5979):689-90. doi: 10.1126/science.328.5979.689. No abstract available. Erratum in: Science. 2010 May 14;328(5980):826.

3.
4.
5.

Role of the prodomain in folding and secretion of rat pancreatic carboxypeptidase A1.

Phillips MA, Rutter WJ.

Biochemistry. 1996 May 28;35(21):6771-6.

PMID:
8639628
6.

Attempts to convert chymotrypsin to trypsin.

Venekei I, Szilágyi L, Gráf L, Rutter WJ.

FEBS Lett. 1996 Mar 25;383(1-2):143-7.

7.

Lineage-specific morphogenesis in the developing pancreas: role of mesenchymal factors.

Gittes GK, Galante PE, Hanahan D, Rutter WJ, Debase HT.

Development. 1996 Feb;122(2):439-47.

8.

Attempts to convert chymotrypsin to trypsin.

Venekei I, Szilágyi L, Gráf L, Rutter WJ.

FEBS Lett. 1996 Jan 29;379(2):143-7. Corrected and republished in: FEBS Lett. 1996 Mar 25;383(1-2):143-7.

10.

A rapid and effective procedure for screening protease mutants.

Venekei I, Hedstrom L, Rutter WJ.

Protein Eng. 1996 Jan;9(1):85-93.

PMID:
9053907
11.

Hxt encodes a basic helix-loop-helix transcription factor that regulates trophoblast cell development.

Cross JC, Flannery ML, Blanar MA, Steingrimsson E, Jenkins NA, Copeland NG, Rutter WJ, Werb Z.

Development. 1995 Aug;121(8):2513-23.

12.

Meso1, a basic-helix-loop-helix protein involved in mammalian presomitic mesoderm development.

Blanar MA, Crossley PH, Peters KG, Steingrímsson E, Copeland NG, Jenkins NA, Martin GR, Rutter WJ.

Proc Natl Acad Sci U S A. 1995 Jun 20;92(13):5870-4.

13.

The minisatellite in the diabetes susceptibility locus IDDM2 regulates insulin transcription.

Kennedy GC, German MS, Rutter WJ.

Nat Genet. 1995 Mar;9(3):293-8.

PMID:
7773292
14.

Engineering ribonuclease A: production, purification and characterization of wild-type enzyme and mutants at Gln11.

delCardayré SB, Ribó M, Yokel EM, Quirk DJ, Rutter WJ, Raines RT.

Protein Eng. 1995 Mar;8(3):261-73.

PMID:
7479688
15.

Structural origins of substrate discrimination in trypsin and chymotrypsin.

Perona JJ, Hedstrom L, Rutter WJ, Fletterick RJ.

Biochemistry. 1995 Feb 7;34(5):1489-99.

PMID:
7849008
16.

Pancreatic beta cells express a diverse set of homeobox genes.

Rudnick A, Ling TY, Odagiri H, Rutter WJ, German MS.

Proc Natl Acad Sci U S A. 1994 Dec 6;91(25):12203-7.

17.

Converting trypsin to chymotrypsin: ground-state binding does not determine substrate specificity.

Hedstrom L, Farr-Jones S, Kettner CA, Rutter WJ.

Biochemistry. 1994 Jul 26;33(29):8764-9.

PMID:
8038166
18.

Converting trypsin to chymotrypsin: residue 172 is a substrate specificity determinant.

Hedstrom L, Perona JJ, Rutter WJ.

Biochemistry. 1994 Jul 26;33(29):8757-63.

PMID:
8038165
19.

Purification of E. coli-synthesized Pan proteins and development of a Pan-specific monoclonal antibody.

Vierra CA, Xin XQ, Jacobs YT, Campbell JM, Shen LP, Rutter WJ, Nelson C.

Hybridoma. 1994 Jun;13(3):191-7.

PMID:
7523277
21.

Positively charged side chains in the insulin-like growth factor-1 C- and D-regions determine receptor binding specificity.

Zhang W, Gustafson TA, Rutter WJ, Johnson JD.

J Biol Chem. 1994 Apr 8;269(14):10609-13.

22.

Exogenous acetate reconstitutes the enzymatic activity of trypsin Asp189Ser.

Perona JJ, Hedstrom L, Wagner RL, Rutter WJ, Craik CS, Fletterick RJ.

Biochemistry. 1994 Mar 22;33(11):3252-9.

PMID:
8136360
23.

Association and phosphorylation-dependent dissociation of proteins in the insulin receptor complex.

Zhang W, Johnson JD, Rutter WJ.

Proc Natl Acad Sci U S A. 1993 Dec 1;90(23):11317-21.

24.

A receptor tyrosine kinase found in breast carcinoma cells has an extracellular discoidin I-like domain.

Johnson JD, Edman JC, Rutter WJ.

Proc Natl Acad Sci U S A. 1993 Nov 15;90(22):10891. No abstract available.

25.
26.
27.

Mapping the S' subsites of serine proteases using acyl transfer to mixtures of peptide nucleophiles.

Schellenberger V, Turck CW, Hedstrom L, Rutter WJ.

Biochemistry. 1993 Apr 27;32(16):4349-53.

PMID:
8476865
28.

Analysis of enzyme specificity by multiple substrate kinetics.

Schellenberger V, Siegel RA, Rutter WJ.

Biochemistry. 1993 Apr 27;32(16):4344-8.

PMID:
8476864
29.

Characterization of a cDNA encoding the insulin gene GAGA-binding factor, Pur-I.

Kennedy GC, Rutter WJ.

Biochem Soc Trans. 1993 Feb;21(1):178-80. No abstract available.

PMID:
8449289
30.

Initiation of gastrin expression during the development of the mouse pancreas.

Gittes GK, Rutter WJ, Debas HT.

Am J Surg. 1993 Jan;165(1):23-5; discussion 25-6.

PMID:
8418699
32.
35.

Human skin mast cell carboxypeptidase: functional characterization, cDNA cloning, and genealogy.

Natsuaki M, Stewart CB, Vanderslice P, Schwartz LB, Natsuaki M, Wintroub BU, Rutter WJ, Goldstein SM.

J Invest Dermatol. 1992 Aug;99(2):138-45.

36.
38.

Guanidine derivatives restore activity to carboxypeptidase lacking arginine-127.

Phillips MA, Hedstrom L, Rutter WJ.

Protein Sci. 1992 Apr;1(4):517-21.

39.

Converting trypsin to chymotrypsin: the role of surface loops.

Hedstrom L, Szilagyi L, Rutter WJ.

Science. 1992 Mar 6;255(5049):1249-53.

PMID:
1546324
40.

Tissue and species differences in bile salt-dependent neutral cholesteryl ester hydrolase activity and gene expression.

Zolfaghari R, Harrison EH, Han JH, Rutter WJ, Fisher EA.

Arterioscler Thromb. 1992 Mar;12(3):295-301.

PMID:
1547189
41.

Transition-state characterization: a new approach combining inhibitor analogues and variation in enzyme structure.

Phillips MA, Kaplan AP, Rutter WJ, Bartlett PA.

Biochemistry. 1992 Feb 4;31(4):959-63.

PMID:
1734971
42.

Onset of cell-specific gene expression in the developing mouse pancreas.

Gittes GK, Rutter WJ.

Proc Natl Acad Sci U S A. 1992 Feb 1;89(3):1128-32.

43.

Insulin-induced surface redistribution regulates internalization of the insulin receptor and requires its autophosphorylation.

Carpentier JL, Paccaud JP, Gorden P, Rutter WJ, Orci L.

Proc Natl Acad Sci U S A. 1992 Jan 1;89(1):162-6.

44.

Synthesis of hepatitis B surface and core antigens in E. coli. 1981.

Edman JC, Hallewell RA, Valenzuela P, Goodman HM, Rutter WJ.

Biotechnology. 1992;24:487-90. No abstract available.

PMID:
1422058
45.

Rat insulin genes: construction of plasmids containing the coding sequences. 1977.

Ullrich A, Shine J, Chirgwin J, Pictet R, Tischer E, Rutter WJ, Goodman HM.

Biotechnology. 1992;24:243-9. No abstract available.

PMID:
1422020
47.

Structural evolution of an enzyme specificity. The structure of rat carboxypeptidase A2 at 1.9-A resolution.

Faming Z, Kobe B, Stewart CB, Rutter WJ, Goldsmith EJ.

J Biol Chem. 1991 Dec 25;266(36):24606-12.

48.
49.

A pancreatic exocrine cell factor and AP4 bind overlapping sites in the amylase 2A enhancer.

Fodor E, Weinrich SL, Meister A, Mermod N, Rutter WJ.

Biochemistry. 1991 Aug 20;30(33):8102-8.

PMID:
1714299
50.

Molecular basis of the activation of the tumorigenic potential of Gag-insulin receptor chimeras.

Poon B, Dixon D, Ellis L, Roth RA, Rutter WJ, Wang LH.

Proc Natl Acad Sci U S A. 1991 Feb 1;88(3):877-81.

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