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Items: 9


Minocycline treatment for pulmonary Mycobacterium avium complex disease based on pharmacokinetics/pharmacodynamics and Bayesian framework mathematical models.

Ruth MM, Magombedze G, Gumbo T, Bendet P, Sangen JJN, Zweijpfenning S, Hoefsloot W, Pennings L, Koeken VACM, Wertheim HFL, Lee PS, van Ingen J, Deshpande D.

J Antimicrob Chemother. 2019 Jul 1;74(7):1952-1961. doi: 10.1093/jac/dkz143.


Failure with acquired resistance of an optimised bedaquiline-based treatment regimen for pulmonary Mycobacterium avium complex disease.

Zweijpfenning SMH, Schildkraut JA, Coolen JPM, Ruesen C, Koenraad E, Janssen A, Ruth MM, de Jong AS, Kuipers S, Aarnoutse RE, Magis-Escurra C, Hoefsloot W, van Ingen J.

Eur Respir J. 2019 Apr 18. pii: 1900118. doi: 10.1183/13993003.00118-2019. [Epub ahead of print] No abstract available.


Implementation of Semiautomated Antimicrobial Susceptibility Interpretation Hardware for Nontuberculous Mycobacteria May Overestimate Susceptibility.

Rockland M, Ruth MM, Aalders N, Pennings L, Hoefsloot W, Wattenberg M, van Ingen J.

J Clin Microbiol. 2019 Mar 28;57(4). pii: e01756-18. doi: 10.1128/JCM.01756-18. Print 2019 Apr.


A bedaquiline/clofazimine combination regimen might add activity to the treatment of clinically relevant non-tuberculous mycobacteria.

Ruth MM, Sangen JJN, Remmers K, Pennings LJ, Svensson E, Aarnoutse RE, Zweijpfenning SMH, Hoefsloot W, Kuipers S, Magis-Escurra C, Wertheim HFL, van Ingen J.

J Antimicrob Chemother. 2019 Apr 1;74(4):935-943. doi: 10.1093/jac/dky526.


Minocycline Has No Clear Role in the Treatment of Mycobacterium abscessus Disease.

Ruth MM, Sangen JJN, Pennings LJ, Schildkraut JA, Hoefsloot W, Magis-Escurra C, Wertheim HFL, van Ingen J.

Antimicrob Agents Chemother. 2018 Sep 24;62(10). pii: e01208-18. doi: 10.1128/AAC.01208-18. Print 2018 Oct.


Mycobacterium avium complex bacteria remain viable in sputum during storage and refrigeration.

Pennings LJ, Zweijpfenning S, Ruth MM, Wattenberg M, Boeree MJ, Hoefsloot W, van Ingen J.

Diagn Microbiol Infect Dis. 2018 Dec;92(4):309-310. doi: 10.1016/j.diagmicrobio.2018.06.017. Epub 2018 Jun 27.


Optimal RNA isolation method and primer design to detect gene knockdown by qPCR when validating Drosophila transgenic RNAi lines.

Mainland RL, Lyons TA, Ruth MM, Kramer JM.

BMC Res Notes. 2017 Nov 29;10(1):647. doi: 10.1186/s13104-017-2959-0.


New insights in the treatment of nontuberculous mycobacterial pulmonary disease.

Ruth MM, van Ingen J.

Future Microbiol. 2017 Oct;12:1109-1112. doi: 10.2217/fmb-2017-0144. Epub 2017 Sep 20. No abstract available.


Nifurtimox Is Ineffective against Drug-Resistant Mycobacteria.

Ruth MM, Sangen JJN, Wertheim HFL, van Ingen J.

Antimicrob Agents Chemother. 2017 Aug 24;61(9). pii: e01233-17. doi: 10.1128/AAC.01233-17. Print 2017 Sep. No abstract available.

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