Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 52


Citrullinated Inhibitor of DNA Binding 1 Is a Novel Autoantigen in Rheumatoid Arthritis.

Ohara RA, Edhayan G, Rasmussen SM, Isozaki T, Remmer HA, Lanigan TM, Campbell PL, Urquhart AG, Lawton JN, Chung KC, Fox DA, Ruth JH.

Arthritis Rheumatol. 2019 Aug;71(8):1241-1251. doi: 10.1002/art.40886. Epub 2019 Jun 21.


A unique role for galectin-9 in angiogenesis and inflammatory arthritis.

O'Brien MJ, Shu Q, Stinson WA, Tsou PS, Ruth JH, Isozaki T, Campbell PL, Ohara RA, Koch AE, Fox DA, Amin MA.

Arthritis Res Ther. 2018 Feb 12;20(1):31. doi: 10.1186/s13075-018-1519-x.


CD318 is a ligand for CD6.

Enyindah-Asonye G, Li Y, Ruth JH, Spassov DS, Hebron KE, Zijlstra A, Moasser MM, Wang B, Singer NG, Cui H, Ohara RA, Rasmussen SM, Fox DA, Lin F.

Proc Natl Acad Sci U S A. 2017 Aug 15;114(33):E6912-E6921. doi: 10.1073/pnas.1704008114. Epub 2017 Jul 31.


Synovial cellular and molecular markers in rheumatoid arthritis.

Asif Amin M, Fox DA, Ruth JH.

Semin Immunopathol. 2017 Jun;39(4):385-393. doi: 10.1007/s00281-017-0631-3. Epub 2017 May 11. Review.


Pharmacokinetic optimitzation of CCG-203971: Novel inhibitors of the Rho/MRTF/SRF transcriptional pathway as potential antifibrotic therapeutics for systemic scleroderma.

Hutchings KM, Lisabeth EM, Rajeswaran W, Wilson MW, Sorenson RJ, Campbell PL, Ruth JH, Amin A, Tsou PS, Leipprandt JR, Olson SR, Wen B, Zhao T, Sun D, Khanna D, Fox DA, Neubig RR, Larsen SD.

Bioorg Med Chem Lett. 2017 Apr 15;27(8):1744-1749. doi: 10.1016/j.bmcl.2017.02.070. Epub 2017 Mar 10.


Inflammatory properties of inhibitor of DNA binding 1 secreted by synovial fibroblasts in rheumatoid arthritis.

Edhayan G, Ohara RA, Stinson WA, Amin MA, Isozaki T, Ha CM, Haines GK 3rd, Morgan R, Campbell PL, Arbab AS, Friday SC, Fox DA, Ruth JH.

Arthritis Res Ther. 2016 Apr 12;18:87. doi: 10.1186/s13075-016-0984-3.


Expression and function of aminopeptidase N/CD13 produced by fibroblast-like synoviocytes in rheumatoid arthritis: role of CD13 in chemotaxis of cytokine-activated T cells independent of enzymatic activity.

Morgan R, Endres J, Behbahani-Nejad N, Phillips K, Ruth JH, Friday SC, Edhayan G, Lanigan T, Urquhart A, Chung KC, Fox DA.

Arthritis Rheumatol. 2015 Jan;67(1):74-85. doi: 10.1002/art.38878.


Citrullination of epithelial neutrophil-activating peptide 78/CXCL5 results in conversion from a non-monocyte-recruiting chemokine to a monocyte-recruiting chemokine.

Yoshida K, Korchynskyi O, Tak PP, Isozaki T, Ruth JH, Campbell PL, Baeten DL, Gerlag DM, Amin MA, Koch AE.

Arthritis Rheumatol. 2014 Oct;66(10):2716-27. doi: 10.1002/art.38750.


Targeting the myofibroblast genetic switch: inhibitors of myocardin-related transcription factor/serum response factor-regulated gene transcription prevent fibrosis in a murine model of skin injury.

Haak AJ, Tsou PS, Amin MA, Ruth JH, Campbell P, Fox DA, Khanna D, Larsen SD, Neubig RR.

J Pharmacol Exp Ther. 2014 Jun;349(3):480-6. doi: 10.1124/jpet.114.213520. Epub 2014 Apr 4.


Fucosyltransferase 1 mediates angiogenesis in rheumatoid arthritis.

Isozaki T, Amin MA, Ruth JH, Campbell PL, Tsou PS, Ha CM, Stinson WA, Domino SE, Koch AE.

Arthritis Rheumatol. 2014 Aug;66(8):2047-58. doi: 10.1002/art.38648.


A key role for Fut1-regulated angiogenesis and ICAM-1 expression in K/BxN arthritis.

Amin MA, Campbell PL, Ruth JH, Isozaki T, Rabquer BJ, Alex Stinson W, O'Brien M, Edhayan G, Ohara RA, Vargo J, Domino SE, Koch AE.

Ann Rheum Dis. 2015 Jul;74(7):1459-66. doi: 10.1136/annrheumdis-2013-204814. Epub 2014 Mar 24.


Inhibitor of DNA binding 1 as a secreted angiogenic transcription factor in rheumatoid arthritis.

Isozaki T, Amin MA, Arbab AS, Koch AE, Ha CM, Edhayan G, Haines GK, Ruth JH.

Arthritis Res Ther. 2014 Mar 13;16(2):R68. doi: 10.1186/ar4507.


Fucosyltransferase 1 mediates angiogenesis, cell adhesion and rheumatoid arthritis synovial tissue fibroblast proliferation.

Isozaki T, Ruth JH, Amin MA, Campbell PL, Tsou PS, Ha CM, Haines GK, Edhayan G, Koch AE.

Arthritis Res Ther. 2014 Jan 28;16(1):R28. doi: 10.1186/ar4456.


Inflammatory mediators of angiogenesis.

Szewczyk G, Rak J, Ruth JH.

Mediators Inflamm. 2013;2013:610543. doi: 10.1155/2013/610543. Epub 2013 Sep 16. No abstract available.


Evidence that CXCL16 is a potent mediator of angiogenesis and is involved in endothelial progenitor cell chemotaxis : studies in mice with K/BxN serum-induced arthritis.

Isozaki T, Arbab AS, Haas CS, Amin MA, Arendt MD, Koch AE, Ruth JH.

Arthritis Rheum. 2013 Jul;65(7):1736-46. doi: 10.1002/art.37981.


ADAM-10 is overexpressed in rheumatoid arthritis synovial tissue and mediates angiogenesis.

Isozaki T, Rabquer BJ, Ruth JH, Haines GK 3rd, Koch AE.

Arthritis Rheum. 2013 Jan;65(1):98-108. doi: 10.1002/art.37755.


A novel role for inducible Fut2 in angiogenesis.

Tsou PS, Ruth JH, Campbell PL, Isozaki T, Lee S, Marotte H, Domino SE, Koch AE, Amin MA.

Angiogenesis. 2013 Jan;16(1):195-205. doi: 10.1007/s10456-012-9312-y. Epub 2012 Oct 12.


H-2g, a glucose analog of blood group H antigen, mediates monocyte recruitment in vitro and in vivo via IL-8/CXCL8.

Rabquer BJ, Hou Y, Ruth JH, Luo W, Eitzman DT, Koch AE, Amin MA.

Open Access Rheumatol. 2012 Sep 18;4:93-98. eCollection 2012.


Suppression of endothelial cell activity by inhibition of TNF╬▒.

Shu Q, Amin MA, Ruth JH, Campbell PL, Koch AE.

Arthritis Res Ther. 2012 Apr 25;14(2):R88. doi: 10.1186/ar3812.


Interleukin 18 induces angiogenesis in vitro and in vivo via Src and Jnk kinases.

Amin MA, Rabquer BJ, Mansfield PJ, Ruth JH, Marotte H, Haas CS, Reamer EN, Koch AE.

Ann Rheum Dis. 2010 Dec;69(12):2204-12. doi: 10.1136/ard.2009.127241. Epub 2010 Aug 2.


Junctional adhesion molecule-C is a soluble mediator of angiogenesis.

Rabquer BJ, Amin MA, Teegala N, Shaheen MK, Tsou PS, Ruth JH, Lesch CA, Imhof BA, Koch AE.

J Immunol. 2010 Aug 1;185(3):1777-85. doi: 10.4049/jimmunol.1000556. Epub 2010 Jun 30.


Interleukin-18 as an in vivo mediator of monocyte recruitment in rodent models of rheumatoid arthritis.

Ruth JH, Park CC, Amin MA, Lesch C, Marotte H, Shahrara S, Koch AE.

Arthritis Res Ther. 2010;12(3):R118. doi: 10.1186/ar3055. Epub 2010 Jun 16.


Expression and function of CXCL16 in a novel model of gout.

Ruth JH, Arendt MD, Amin MA, Ahmed S, Marotte H, Rabquer BJ, Lesch C, Lee S, Koch AE.

Arthritis Rheum. 2010 Aug;62(8):2536-44. doi: 10.1002/art.27518.


Green tea extract inhibits chemokine production, but up-regulates chemokine receptor expression, in rheumatoid arthritis synovial fibroblasts and rat adjuvant-induced arthritis.

Marotte H, Ruth JH, Campbell PL, Koch AE, Ahmed S.

Rheumatology (Oxford). 2010 Mar;49(3):467-79. doi: 10.1093/rheumatology/kep397. Epub 2009 Dec 23.


Epigallocatechin-3-gallate inhibits IL-6 synthesis and suppresses transsignaling by enhancing soluble gp130 production.

Ahmed S, Marotte H, Kwan K, Ruth JH, Campbell PL, Rabquer BJ, Pakozdi A, Koch AE.

Proc Natl Acad Sci U S A. 2008 Sep 23;105(38):14692-7. doi: 10.1073/pnas.0802675105. Epub 2008 Sep 16.


H-2g, a glucose analog of blood group H antigen, mediates mononuclear cell recruitment via Src and phosphatidylinositol 3-kinase pathways.

Amin MA, Ruth JH, Haas CS, Pakozdi A, Mansfield PJ, Haghshenas J, Koch AE.

Arthritis Rheum. 2008 Mar;58(3):689-95. doi: 10.1002/art.23296.


In vivo inhibition of angiogenesis by interleukin-13 gene therapy in a rat model of rheumatoid arthritis.

Haas CS, Amin MA, Ruth JH, Allen BL, Ahmed S, Pakozdi A, Woods JM, Shahrara S, Koch AE.

Arthritis Rheum. 2007 Aug;56(8):2535-48.


ICOS and B7 costimulatory molecule expression identifies activated cellular subsets in rheumatoid arthritis.

Ruth JH, Rottman JB, Kingsbury GA, Coyle AJ, Haines GK 3rd, Pope RM, Koch AE.

Cytometry A. 2007 May;71(5):317-26.


The DEK nuclear autoantigen is a secreted chemotactic factor.

Mor-Vaknin N, Punturieri A, Sitwala K, Faulkner N, Legendre M, Khodadoust MS, Kappes F, Ruth JH, Koch A, Glass D, Petruzzelli L, Adams BS, Markovitz DM.

Mol Cell Biol. 2006 Dec;26(24):9484-96. Epub 2006 Oct 9.


Inhibition of angiogenesis by interleukin-4 gene therapy in rat adjuvant-induced arthritis.

Haas CS, Amin MA, Allen BB, Ruth JH, Haines GK 3rd, Woods JM, Koch AE.

Arthritis Rheum. 2006 Aug;54(8):2402-14.


CXCL16-mediated cell recruitment to rheumatoid arthritis synovial tissue and murine lymph nodes is dependent upon the MAPK pathway.

Ruth JH, Haas CS, Park CC, Amin MA, Martinez RJ, Haines GK 3rd, Shahrara S, Campbell PL, Koch AE.

Arthritis Rheum. 2006 Mar;54(3):765-78.


Accelerated development of arthritis in mice lacking endothelial selectins.

Ruth JH, Amin MA, Woods JM, He X, Samuel S, Yi N, Haas CS, Koch AE, Bullard DC.

Arthritis Res Ther. 2005;7(5):R959-70. Epub 2005 Jun 15.


Amelioration of rat adjuvant-induced arthritis by Met-RANTES.

Shahrara S, Proudfoot AE, Woods JM, Ruth JH, Amin MA, Park CC, Haas CS, Pope RM, Haines GK, Zha YY, Koch AE.

Arthritis Rheum. 2005 Jun;52(6):1907-19.


Role of macrophage inflammatory protein-3alpha and its ligand CCR6 in rheumatoid arthritis.

Ruth JH, Shahrara S, Park CC, Morel JC, Kumar P, Qin S, Koch AE.

Lab Invest. 2003 Apr;83(4):579-88.


Signal transduction pathways involved in rheumatoid arthritis synovial fibroblast interleukin-18-induced vascular cell adhesion molecule-1 expression.

Morel JC, Park CC, Zhu K, Kumar P, Ruth JH, Koch AE.

J Biol Chem. 2002 Sep 20;277(38):34679-91. Epub 2002 Jul 8.


Interleukin-13 gene therapy reduces inflammation, vascularization, and bony destruction in rat adjuvant-induced arthritis.

Woods JM, Amin MA, Katschke KJ Jr, Volin MV, Ruth JH, Connors MA, Woodruff DC, Kurata H, Arai K, Haines GK 3rd, Kumar P, Koch AE.

Hum Gene Ther. 2002 Feb 10;13(3):381-93.


Selective lymphocyte chemokine receptor expression in the rheumatoid joint.

Ruth JH, Rottman JB, Katschke KJ Jr, Qin S, Wu L, LaRosa G, Ponath P, Pope RM, Koch AE.

Arthritis Rheum. 2001 Dec;44(12):2750-60.


Fractalkine, a novel chemokine in rheumatoid arthritis and in rat adjuvant-induced arthritis.

Ruth JH, Volin MV, Haines GK 3rd, Woodruff DC, Katschke KJ Jr, Woods JM, Park CC, Morel JC, Koch AE.

Arthritis Rheum. 2001 Jul;44(7):1568-81.


Differential expression of chemokine receptors on peripheral blood, synovial fluid, and synovial tissue monocytes/macrophages in rheumatoid arthritis.

Katschke KJ Jr, Rottman JB, Ruth JH, Qin S, Wu L, LaRosa G, Ponath P, Park CC, Pope RM, Koch AE.

Arthritis Rheum. 2001 May;44(5):1022-32.


IL-4 adenoviral gene therapy reduces inflammation, proinflammatory cytokines, vascularization, and bony destruction in rat adjuvant-induced arthritis.

Woods JM, Katschke KJ, Volin MV, Ruth JH, Woodruff DC, Amin MA, Connors MA, Kurata H, Arai K, Haines GK, Kumar P, Koch AE.

J Immunol. 2001 Jan 15;166(2):1214-22.


Effect of C-C chemokine receptor 2 (CCR2) knockout on type-2 (schistosomal antigen-elicited) pulmonary granuloma formation: analysis of cellular recruitment and cytokine responses.

Warmington KS, Boring L, Ruth JH, Sonstein J, Hogaboam CM, Curtis JL, Kunkel SL, Charo IR, Chensue SW.

Am J Pathol. 1999 May;154(5):1407-16.


Expression and participation of eotaxin during mycobacterial (type 1) and schistosomal (type 2) antigen-elicited granuloma formation.

Ruth JH, Lukacs NW, Warmington KS, Polak TJ, Burdick M, Kunkel SL, Strieter RM, Chensue SW.

J Immunol. 1998 Oct 15;161(8):4276-82.


Mycobacterial and schistosomal antigen-elicited granuloma formation in IFN-gamma and IL-4 knockout mice: analysis of local and regional cytokine and chemokine networks.

Chensue SW, Warmington K, Ruth JH, Lukacs N, Kunkel SL.

J Immunol. 1997 Oct 1;159(7):3565-73. Erratum in: J Immunol 1999 Mar 1;162(5):3106.


IL-1 receptor antagonist (IL-1ra) expression, function, and cytokine-mediated regulation during mycobacterial and schistosomal antigen-elicited granuloma formation.

Ruth JH, Bienkowski M, Warmington KS, Lincoln PM, Kunkel SL, Chensue SW.

J Immunol. 1996 Apr 1;156(7):2503-9.


In vivo regulation of macrophage IL-12 production during type 1 and type 2 cytokine-mediated granuloma formation.

Chensue SW, Ruth JH, Warmington K, Lincoln P, Kunkel SL.

J Immunol. 1995 Oct 1;155(7):3546-51.


Supplemental Content

Support Center