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Items: 1 to 50 of 209

1.

A parsimonious 3-gene signature predicts clinical outcomes in an acute myeloid leukemia multicohort study.

Wagner S, Vadakekolathu J, Tasian SK, Altmann H, Bornhäuser M, Pockley AG, Ball GR, Rutella S.

Blood Adv. 2019 Apr 23;3(8):1330-1346. doi: 10.1182/bloodadvances.2018030726.

2.

Dissecting the Immune Landscape of Acute Myeloid Leukemia.

Davidson-Moncada J, Viboch E, Church SE, Warren SE, Rutella S.

Biomedicines. 2018 Nov 25;6(4). pii: E110. doi: 10.3390/biomedicines6040110. Review.

3.

Immune-Phenotyping and Transcriptomic Profiling of Peripheral Blood Mononuclear Cells From Patients With Breast Cancer: Identification of a 3 Gene Signature Which Predicts Relapse of Triple Negative Breast Cancer.

Foulds GA, Vadakekolathu J, Abdel-Fatah TMA, Nagarajan D, Reeder S, Johnson C, Hood S, Moseley PM, Chan SYT, Pockley AG, Rutella S, McArdle SEB.

Front Immunol. 2018 Sep 11;9:2028. doi: 10.3389/fimmu.2018.02028. eCollection 2018.

4.

An Artificial Neural Network Integrated Pipeline for Biomarker Discovery Using Alzheimer's Disease as a Case Study.

Zafeiris D, Rutella S, Ball GR.

Comput Struct Biotechnol J. 2018 Feb 21;16:77-87. doi: 10.1016/j.csbj.2018.02.001. eCollection 2018. Review.

5.

Neutrophils Kill Antibody-Opsonized Cancer Cells by Trogoptosis.

Matlung HL, Babes L, Zhao XW, van Houdt M, Treffers LW, van Rees DJ, Franke K, Schornagel K, Verkuijlen P, Janssen H, Halonen P, Lieftink C, Beijersbergen RL, Leusen JHW, Boelens JJ, Kuhnle I, van der Werff Ten Bosch J, Seeger K, Rutella S, Pagliara D, Matozaki T, Suzuki E, Menke-van der Houven van Oordt CW, van Bruggen R, Roos D, van Lier RAW, Kuijpers TW, Kubes P, van den Berg TK.

Cell Rep. 2018 Jun 26;23(13):3946-3959.e6. doi: 10.1016/j.celrep.2018.05.082.

7.

Targeting Leukemia Stem Cells in the Bone Marrow Niche.

Tasian SK, Bornhäuser M, Rutella S.

Biomedicines. 2018 Feb 21;6(1). pii: E22. doi: 10.3390/biomedicines6010022. Review.

8.

Discovery and application of immune biomarkers for hematological malignancies.

Zafeiris D, Vadakekolathu J, Wagner S, Pockley AG, Ball GR, Rutella S.

Expert Rev Mol Diagn. 2017 Nov;17(11):983-1000. doi: 10.1080/14737159.2017.1381560. Epub 2017 Sep 25. Review.

PMID:
28927305
9.

T-Cell Manipulation Strategies to Prevent Graft-Versus-Host Disease in Haploidentical Stem Cell Transplantation.

Vadakekolathu J, Rutella S.

Biomedicines. 2017 Jun 21;5(2). pii: E33. doi: 10.3390/biomedicines5020033. Review.

10.

Systematic evaluation of immune regulation and modulation.

Stroncek DF, Butterfield LH, Cannarile MA, Dhodapkar MV, Greten TF, Grivel JC, Kaufman DR, Kong HH, Korangy F, Lee PP, Marincola F, Rutella S, Siebert JC, Trinchieri G, Seliger B.

J Immunother Cancer. 2017 Mar 21;5:21. doi: 10.1186/s40425-017-0223-8. eCollection 2017. Review.

11.

Evidence for CD19B-CD8T cell interactions in blood and tissues from patients with GvHD.

Deola S, Cugno C, Comoli P, Guido I, Rubert L, Zecca M, Zanolini D, Follenzi A, Langes M, Negri G, Tauber M, Pusceddu I, Cavattoni I, Svaldi M, Grigoleit GU, Baumeister E, Wang E, Rutella S, Marincola FM.

Bone Marrow Transplant. 2017 Mar;52(3):459-462. doi: 10.1038/bmt.2016.294. Epub 2016 Nov 7. No abstract available.

12.

Integrative systems medicine approaches to identify molecular targets in lymphoid malignancies.

Frazzi R, Auffray C, Ferrari A, Filippini P, Rutella S, Cesario A.

J Transl Med. 2016 Sep 1;14:252. doi: 10.1186/s12967-016-1018-2. Review.

13.

Granulocyte transfusions in children and adults with hematological malignancies: benefits and controversies.

Cugno C, Deola S, Filippini P, Stroncek DF, Rutella S.

J Transl Med. 2015 Nov 16;13:362. doi: 10.1186/s12967-015-0724-5. Review.

14.

Reduced cortical thickness in patients with acute-on-chronic liver failure due to non-alcoholic etiology.

Yadav SK, Gupta RK, Saraswat VA, Rangan M, Thomas MA, Rutella S, Danese S, Wang E, Marincola FM, Haris M.

J Transl Med. 2015 Oct 6;13:322. doi: 10.1186/s12967-015-0679-6.

15.

Circulating hematopoietic stem cells and putative intestinal stem cells in coeliac disease.

Piscaglia AC, Rutella S, Laterza L, Cesario V, Campanale M, Cazzato IA, Ianiro G, Barbaro F, Di Maurizio L, Bonanno G, Cenci T, Cammarota G, Larocca LM, Gasbarrini A.

J Transl Med. 2015 Jul 11;13:220. doi: 10.1186/s12967-015-0591-0.

16.

Revving up Natural Killer Cells and Cytokine-Induced Killer Cells Against Hematological Malignancies.

Pittari G, Filippini P, Gentilcore G, Grivel JC, Rutella S.

Front Immunol. 2015 May 13;6:230. doi: 10.3389/fimmu.2015.00230. eCollection 2015. Review.

17.

Mesenchymal Stem Cells Reduce Colitis in Mice via Release of TSG6, Independently of Their Localization to the Intestine.

Sala E, Genua M, Petti L, Anselmo A, Arena V, Cibella J, Zanotti L, D'Alessio S, Scaldaferri F, Luca G, Arato I, Calafiore R, Sgambato A, Rutella S, Locati M, Danese S, Vetrano S.

Gastroenterology. 2015 Jul;149(1):163-176.e20. doi: 10.1053/j.gastro.2015.03.013. Epub 2015 Mar 17.

PMID:
25790743
18.

Outcome of children with high-risk acute myeloid leukemia given autologous or allogeneic hematopoietic cell transplantation in the aieop AML-2002/01 study.

Locatelli F, Masetti R, Rondelli R, Zecca M, Fagioli F, Rovelli A, Messina C, Lanino E, Bertaina A, Favre C, Giorgiani G, Ripaldi M, Ziino O, Palumbo G, Pillon M, Pession A, Rutella S, Prete A.

Bone Marrow Transplant. 2015 Feb;50(2):181-8. doi: 10.1038/bmt.2014.246. Epub 2014 Nov 10. Erratum in: Bone Marrow Transplant. 2015 Feb;50(2):320.

PMID:
25387094
19.

The triggering receptor expressed on myeloid cells (TREM) in inflammatory bowel disease pathogenesis.

Genua M, Rutella S, Correale C, Danese S.

J Transl Med. 2014 Oct 28;12:293. doi: 10.1186/s12967-014-0293-z. Review.

20.

Recent advances on cellular therapies and immune modulators for graft-versus-host disease.

Filippini P, Rutella S.

Expert Rev Clin Immunol. 2014 Oct;10(10):1357-74. doi: 10.1586/1744666X.2014.955475. Epub 2014 Sep 8. Review.

PMID:
25196777
21.

Mobilization of healthy donors with plerixafor affects the cellular composition of T-cell receptor (TCR)-αβ/CD19-depleted haploidentical stem cell grafts.

Rutella S, Filippini P, Bertaina V, Li Pira G, Altomare L, Ceccarelli S, Brescia LP, Lucarelli B, Girolami E, Conflitti G, Cefalo MG, Bertaina A, Corsetti T, Moretta L, Locatelli F.

J Transl Med. 2014 Sep 2;12:240. doi: 10.1186/s12967-014-0240-z.

22.

Extracorporeal membrane oxygenation as a bridge to allogeneic T-cell depleted hematopoietic stem cell transplantation in infants with severe combined immune deficiency: is it feasible?

Di Nardo M, Locatelli F, Di Florio F, Cecchetti C, Amodeo A, Rutella S, Bertaina A.

Intensive Care Med. 2014 Oct;40(10):1600-1. doi: 10.1007/s00134-014-3432-3. Epub 2014 Aug 12. No abstract available.

PMID:
25112503
23.

A registry of HLA-typed donors for production of virus-specific CD4 and CD8 T lymphocytes for adoptive reconstitution of immune-compromised patients.

Li Pira G, Ivaldi F, Starc N, Landi F, Rutella S, Locatelli F, Sacchi N, Tripodi G, Manca F.

Transfusion. 2014 Dec;54(12):3145-54. doi: 10.1111/trf.12754. Epub 2014 Jul 20.

PMID:
25041366
24.

Indoleamine 2,3-dioxygenase 1 (IDO1) activity in leukemia blasts correlates with poor outcome in childhood acute myeloid leukemia.

Folgiero V, Goffredo BM, Filippini P, Masetti R, Bonanno G, Caruso R, Bertaina V, Mastronuzzi A, Gaspari S, Zecca M, Torelli GF, Testi AM, Pession A, Locatelli F, Rutella S.

Oncotarget. 2014 Apr 30;5(8):2052-64.

25.

HLA-haploidentical stem cell transplantation after removal of αβ+ T and B cells in children with nonmalignant disorders.

Bertaina A, Merli P, Rutella S, Pagliara D, Bernardo ME, Masetti R, Pende D, Falco M, Handgretinger R, Moretta F, Lucarelli B, Brescia LP, Li Pira G, Testi M, Cancrini C, Kabbara N, Carsetti R, Finocchi A, Moretta A, Moretta L, Locatelli F.

Blood. 2014 Jul 31;124(5):822-6. doi: 10.1182/blood-2014-03-563817. Epub 2014 May 28.

PMID:
24869942
26.

The urokinase plasminogen activator receptor (uPAR) controls macrophage phagocytosis in intestinal inflammation.

Genua M, D'Alessio S, Cibella J, Gandelli A, Sala E, Correale C, Spinelli A, Arena V, Malesci A, Rutella S, Ploplis VA, Vetrano S, Danese S.

Gut. 2015 Apr;64(4):589-600. doi: 10.1136/gutjnl-2013-305933. Epub 2014 May 21. Erratum in: Gut. 2015 Sep;64(9):1465.

PMID:
24848264
27.

Extracorporeal photopheresis for paediatric patients experiencing graft-versus-host disease (GVHD).

Rutella S, Valentini CG, Ceccarelli S, Romano MT, Brescia LP, Milano GM, Locatelli F.

Transfus Apher Sci. 2014 Jun;50(3):340-8. doi: 10.1016/j.transci.2014.04.004. Epub 2014 Apr 13. Review.

PMID:
24780391
28.

Whole transcriptome sequencing of a paediatric case of de novo acute myeloid leukaemia with del(5q) reveals RUNX1-USP42 and PRDM16-SKI fusion transcripts.

Masetti R, Togni M, Astolfi A, Pigazzi M, Indio V, Rivalta B, Manara E, Rutella S, Basso G, Pession A, Locatelli F.

Br J Haematol. 2014 Aug;166(3):449-52. doi: 10.1111/bjh.12855. Epub 2014 Mar 27. Review. No abstract available.

PMID:
24673627
29.

Extracorporeal membrane oxygenation in pediatric recipients of hematopoietic stem cell transplantation: an updated analysis of the Extracorporeal Life Support Organization experience.

Di Nardo M, Locatelli F, Palmer K, Amodeo A, Lorusso R, Belliato M, Cecchetti C, Perrotta D, Picardo S, Bertaina A, Rutella S, Rycus P, Di Ciommo V, Holzgraefe B.

Intensive Care Med. 2014 May;40(5):754-6. doi: 10.1007/s00134-014-3240-9. Epub 2014 Feb 21. No abstract available.

PMID:
24556913
30.

Miniaturized and high-throughput assays for analysis of T-cell immunity specific for opportunistic pathogens and HIV.

Li Pira G, Ivaldi F, Starc N, Landi F, Locatelli F, Rutella S, Tripodi G, Manca F.

Clin Vaccine Immunol. 2014 Apr;21(4):488-95. doi: 10.1128/CVI.00660-13. Epub 2014 Jan 29.

31.

Kindlin-3-independent adhesion of neutrophils from patients with leukocyte adhesion deficiency type III.

van de Vijver E, Tool AT, Sanal Ö, Çetin M, Ünal S, Aytac S, Seeger K, Pagliara D, Rutella S, van den Berg TK, Kuijpers TW.

J Allergy Clin Immunol. 2014 Apr;133(4):1215-8. doi: 10.1016/j.jaci.2013.10.020. Epub 2013 Dec 15. No abstract available.

PMID:
24342549
32.

The Polycomb group (PcG) protein EZH2 supports the survival of PAX3-FOXO1 alveolar rhabdomyosarcoma by repressing FBXO32 (Atrogin1/MAFbx).

Ciarapica R, De Salvo M, Carcarino E, Bracaglia G, Adesso L, Leoncini PP, Dall'Agnese A, Walters ZS, Verginelli F, De Sio L, Boldrini R, Inserra A, Bisogno G, Rosolen A, Alaggio R, Ferrari A, Collini P, Locatelli M, Stifani S, Screpanti I, Rutella S, Yu Q, Marquez VE, Shipley J, Valente S, Mai A, Miele L, Puri PL, Locatelli F, Palacios D, Rota R.

Oncogene. 2014 Aug 7;33(32):4173-84. doi: 10.1038/onc.2013.471. Epub 2013 Nov 11.

PMID:
24213577
33.

DHH-RHEBL1 fusion transcript: a novel recurrent feature in the new landscape of pediatric CBFA2T3-GLIS2-positive acute myeloid leukemia.

Masetti R, Togni M, Astolfi A, Pigazzi M, Manara E, Indio V, Rizzari C, Rutella S, Basso G, Pession A, Locatelli F.

Oncotarget. 2013 Oct;4(10):1712-20.

34.

At the Bedside: Innate immunity as an immunotherapy tool for hematological malignancies.

Locatelli F, Merli P, Rutella S.

J Leukoc Biol. 2013 Dec;94(6):1141-57. doi: 10.1189/jlb.0613343. Epub 2013 Oct 4. Review.

PMID:
24096380
35.

Management of relapsed acute lymphoblastic leukemia in childhood with conventional and innovative approaches.

Locatelli F, Moretta F, Rutella S.

Curr Opin Oncol. 2013 Nov;25(6):707-15. doi: 10.1097/CCO.0000000000000011. Review.

PMID:
24076579
36.

FOXP3⁺ T regulatory cell modifications in inflammatory bowel disease patients treated with anti-TNFα agents.

Guidi L, Felice C, Procoli A, Bonanno G, Martinelli E, Marzo M, Mocci G, Pugliese D, Andrisani G, Danese S, De Vitis I, Papa A, Armuzzi A, Rutella S.

Biomed Res Int. 2013;2013:286368. doi: 10.1155/2013/286368. Epub 2013 Aug 26.

37.

Adoptive immunotherapy with antigen-specific T cells during extracorporeal membrane oxygenation (ECMO) for adenovirus-related respiratory failure in a child given haploidentical stem cell transplantation.

Di Nardo M, Li Pira G, Amodeo A, Cecchetti C, Giorda E, Ceccarelli S, Brescia LP, Pirozzi N, Rutella S, Locatelli F, Bertaina A.

Pediatr Blood Cancer. 2014 Feb;61(2):376-9. doi: 10.1002/pbc.24753. Epub 2013 Aug 26.

PMID:
24039155
38.

Cyclooxygenase-2 (COX-2) inhibition constrains indoleamine 2,3-dioxygenase 1 (IDO1) activity in acute myeloid leukaemia cells.

Iachininoto MG, Nuzzolo ER, Bonanno G, Mariotti A, Procoli A, Locatelli F, De Cristofaro R, Rutella S.

Molecules. 2013 Aug 22;18(9):10132-45. doi: 10.3390/molecules180910132.

39.

Results of the AIEOP AML 2002/01 multicenter prospective trial for the treatment of children with acute myeloid leukemia.

Pession A, Masetti R, Rizzari C, Putti MC, Casale F, Fagioli F, Luciani M, Lo Nigro L, Menna G, Micalizzi C, Santoro N, Testi AM, Zecca M, Biondi A, Pigazzi M, Rutella S, Rondelli R, Basso G, Locatelli F; AIEOP AML Study Group.

Blood. 2013 Jul 11;122(2):170-8. doi: 10.1182/blood-2013-03-491621. Epub 2013 May 14.

PMID:
23673857
40.

Hematopoietic stem cell transplantation for children with high-risk acute lymphoblastic leukemia in first complete remission: a report from the AIEOP registry.

Fagioli F, Quarello P, Zecca M, Lanino E, Rognoni C, Balduzzi A, Messina C, Favre C, Foà R, Ripaldi M, Rutella S, Basso G, Prete A, Locatelli F.

Haematologica. 2013 Aug;98(8):1273-81. doi: 10.3324/haematol.2012.079707. Epub 2013 Feb 26.

41.

A novel flow cytometry-based platelet aggregation assay.

De Cuyper IM, Meinders M, van de Vijver E, de Korte D, Porcelijn L, de Haas M, Eble JA, Seeger K, Rutella S, Pagliara D, Kuijpers TW, Verhoeven AJ, van den Berg TK, Gutiérrez L.

Blood. 2013 Mar 7;121(10):e70-80. doi: 10.1182/blood-2012-06-437723. Epub 2013 Jan 9.

PMID:
23303822
42.

Mesenchymal stromal cells in inflammatory bowel disease: conspirators within the 'colitogenic niche'?

Danese S, Rutella S, Vetrano S.

Gut. 2013 Aug;62(8):1098-9. doi: 10.1136/gutjnl-2012-303903. Epub 2012 Dec 22. No abstract available.

PMID:
23263523
43.

Indoleamine 2,3-dioxygenase 1 (IDO1) activity correlates with immune system abnormalities in multiple myeloma.

Bonanno G, Mariotti A, Procoli A, Folgiero V, Natale D, De Rosa L, Majolino I, Novarese L, Rocci A, Gambella M, Ciciarello M, Scambia G, Palumbo A, Locatelli F, De Cristofaro R, Rutella S.

J Transl Med. 2012 Dec 11;10:247. doi: 10.1186/1479-5876-10-247.

44.

Bacterial sensor triggering receptor expressed on myeloid cells-2 regulates the mucosal inflammatory response.

Correale C, Genua M, Vetrano S, Mazzini E, Martinoli C, Spinelli A, Arena V, Peyrin-Biroulet L, Caprioli F, Passini N, Panina-Bordignon P, Repici A, Malesci A, Rutella S, Rescigno M, Danese S.

Gastroenterology. 2013 Feb;144(2):346-356.e3. doi: 10.1053/j.gastro.2012.10.040. Epub 2012 Oct 26.

PMID:
23108068
45.

Is there a role for cytokine-induced killer cells in cancer immunotherapy?

Rutella S, Locatelli F.

Immunotherapy. 2012 Sep;4(9):867-9. doi: 10.2217/imt.12.89. No abstract available.

PMID:
23046228
46.

Regulatory T-cell therapy for Crohn's disease: in vivo veritas.

Danese S, Fiorino G, Rutella S.

Gastroenterology. 2012 Nov;143(5):1135-1138. doi: 10.1053/j.gastro.2012.09.019. Epub 2012 Sep 20. No abstract available.

PMID:
23000230
47.

Lymphocyte proliferation specific for recall, CMV and HIV antigens in miniaturized and automated format.

Li Pira G, Starc N, Conforti A, Bertaina A, Rutella S, Locatelli F, Manca F.

J Immunol Methods. 2012 Oct 31;384(1-2):135-42.

PMID:
22967924
48.

Emerging concepts on inhibitors of indoleamine 2,3-dioxygenase in rheumatic diseases.

Filippini P, Del Papa N, Sambataro D, Del Bufalo A, Locatelli F, Rutella S.

Curr Med Chem. 2012;19(31):5381-93. Review.

PMID:
22963664
49.

How I treat relapsed childhood acute lymphoblastic leukemia.

Locatelli F, Schrappe M, Bernardo ME, Rutella S.

Blood. 2012 Oct 4;120(14):2807-16. doi: 10.1182/blood-2012-02-265884. Epub 2012 Aug 15.

PMID:
22896001
50.

Targeting multiple-myeloma-induced immune dysfunction to improve immunotherapy outcomes.

Rutella S, Locatelli F.

Clin Dev Immunol. 2012;2012:196063. doi: 10.1155/2012/196063. Epub 2012 Apr 11. Review.

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