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Comment on "Unraveling a Clinical Paradox: Why Does Bronchial Thermoplasty Work in Asthma?"

Brook BS, Chernyavsky IL, Russell RJ, Saunders RM, Brightling CE.

Am J Respir Cell Mol Biol. 2019 Nov;61(5):660-661. doi: 10.1165/rcmb.2019-0095LE. No abstract available.


ERS/EAACI statement on severe exacerbations in asthma in adults: facts, priorities and key research questions.

Bourdin A, Bjermer L, Brightling C, Brusselle GG, Chanez P, Chung KF, Custovic A, Diamant Z, Diver S, Djukanovic R, Hamerlijnck D, Horváth I, Johnston SL, Kanniess F, Papadopoulos N, Papi A, Russell RJ, Ryan D, Samitas K, Tonia T, Zervas E, Gaga M.

Eur Respir J. 2019 Sep 28;54(3). pii: 1900900. doi: 10.1183/13993003.00900-2019. Print 2019 Sep.


Cough and Eosinophilia.

Diver S, Russell RJ, Brightling CE.

J Allergy Clin Immunol Pract. 2019 Jul - Aug;7(6):1740-1747. doi: 10.1016/j.jaip.2019.04.048.



Hill AT, Gold PM, El Solh AA, Metlay JP, Ireland B, Irwin RS; CHEST Expert Cough Panel.

Chest. 2019 May;155(5):1082-1083. doi: 10.1016/j.chest.2019.02.014. No abstract available.


Chronic Cough and Gastroesophageal Reflux in Children: CHEST Guideline and Expert Panel Report.

Chang AB, Oppenheimer JJ, Kahrilas PJ, Kantar A, Rubin BK, Weinberger M, Irwin RS; CHEST Expert Cough Panel.

Chest. 2019 Jul;156(1):131-140. doi: 10.1016/j.chest.2019.03.035. Epub 2019 Apr 16.


Thrombospondin-1 Is a Major Activator of TGF-β Signaling in Recessive Dystrophic Epidermolysis Bullosa Fibroblasts.

Atanasova VS, Russell RJ, Webster TG, Cao Q, Agarwal P, Lim YZ, Krishnan S, Fuentes I, Guttmann-Gruber C, McGrath JA, Salas-Alanis JC, Fertala A, South AP.

J Invest Dermatol. 2019 Jul;139(7):1497-1505.e5. doi: 10.1016/j.jid.2019.01.011. Epub 2019 Jan 23.


Clinically Diagnosing Pertussis-associated Cough in Adults and Children: CHEST Guideline and Expert Panel Report.

Moore A, Harnden A, Grant CC, Patel S, Irwin RS; CHEST Expert Cough Panel.

Chest. 2019 Jan;155(1):147-154. doi: 10.1016/j.chest.2018.09.027. Epub 2018 Oct 12. Review.


Adult Outpatients With Acute Cough Due to Suspected Pneumonia or Influenza: CHEST Guideline and Expert Panel Report.

Hill AT, Gold PM, El Solh AA, Metlay JP, Ireland B, Irwin RS; CHEST Expert Cough Panel.

Chest. 2019 Jan;155(1):155-167. doi: 10.1016/j.chest.2018.09.016. Epub 2018 Oct 6. Review.


Effect of tralokinumab, an interleukin-13 neutralising monoclonal antibody, on eosinophilic airway inflammation in uncontrolled moderate-to-severe asthma (MESOS): a multicentre, double-blind, randomised, placebo-controlled phase 2 trial.

Russell RJ, Chachi L, FitzGerald JM, Backer V, Olivenstein R, Titlestad IL, Ulrik CS, Harrison T, Singh D, Chaudhuri R, Leaker B, McGarvey L, Siddiqui S, Wang M, Braddock M, Nordenmark LH, Cohen D, Parikh H, Colice G, Brightling CE; MESOS study investigators.

Lancet Respir Med. 2018 Jul;6(7):499-510. doi: 10.1016/S2213-2600(18)30201-7. Epub 2018 May 21.


In vitro, in silico and in vivo study challenges the impact of bronchial thermoplasty on acute airway smooth muscle mass loss.

Chernyavsky IL, Russell RJ, Saunders RM, Morris GE, Berair R, Singapuri A, Chachi L, Mansur AH, Howarth PH, Dennison P, Chaudhuri R, Bicknell S, Rose FRAJ, Siddiqui S, Brook BS, Brightling CE.

Eur Respir J. 2018 May 24;51(5). pii: 1701680. doi: 10.1183/13993003.01680-2017. Print 2018 May.


New and emerging drug treatments for severe asthma.

Diver S, Russell RJ, Brightling CE.

Clin Exp Allergy. 2018 Mar;48(3):241-252. doi: 10.1111/cea.13086. Epub 2018 Feb 13. Review.


Pathogenesis of asthma: implications for precision medicine.

Russell RJ, Brightling C.

Clin Sci (Lond). 2017 Jun 30;131(14):1723-1735. doi: 10.1042/CS20160253. Print 2017 Jul 15. Review.


Mycobacterial F420H2-Dependent Reductases Promiscuously Reduce Diverse Compounds through a Common Mechanism.

Greening C, Jirapanjawat T, Afroze S, Ney B, Scott C, Pandey G, Lee BM, Russell RJ, Jackson CJ, Oakeshott JG, Taylor MC, Warden AC.

Front Microbiol. 2017 May 31;8:1000. doi: 10.3389/fmicb.2017.01000. eCollection 2017.


The Redox Cofactor F420 Protects Mycobacteria from Diverse Antimicrobial Compounds and Mediates a Reductive Detoxification System.

Jirapanjawat T, Ney B, Taylor MC, Warden AC, Afroze S, Russell RJ, Lee BM, Jackson CJ, Oakeshott JG, Pandey G, Greening C.

Appl Environ Microbiol. 2016 Dec 1;82(23):6810-6818. doi: 10.1128/AEM.02500-16. Epub 2016 Sep 16.


Elimination of biofilm and microbial contamination reservoirs in hospital washbasin U-bends by automated cleaning and disinfection with electrochemically activated solutions.

Swan JS, Deasy EC, Boyle MA, Russell RJ, O'Donnell MJ, Coleman DC.

J Hosp Infect. 2016 Oct;94(2):169-74. doi: 10.1016/j.jhin.2016.07.007. Epub 2016 Jul 18.


Dismounted Complex Blast Injuries Including Invasive Fungal Infections.

Murray CK, Gross K, Russell RJ, Haslett RA.

US Army Med Dep J. 2016 Apr-Sep;(2-16):24-8.


Died of wounds: a mortality review.

Keene DD, Penn-Barwell JG, Wood PR, Hunt N, Delaney R, Clasper J, Russell RJ, Mahoney PF.

J R Army Med Corps. 2016 Oct;162(5):355-360. doi: 10.1136/jramc-2015-000490. Epub 2015 Oct 14.


Overcoming the problem of residual microbial contamination in dental suction units left by conventional disinfection using novel single component suction handpieces in combination with automated flood disinfection.

Boyle MA, O'Donnell MJ, Russell RJ, Galvin N, Swan J, Coleman DC.

J Dent. 2015 Oct;43(10):1268-79. doi: 10.1016/j.jdent.2015.07.018. Epub 2015 Aug 3.


Replacement of Promethazine With Ondansetron for Treatment of Opioid- and Trauma-Related Nausea and Vomiting in Tactical Combat Casualty Care.

Onifer DJ, Butler FK, Gross KR, Otten EJ, Patton R, Russell RJ, Stockinger Z, Burrell E.

J Spec Oper Med. 2015 Summer;15(2):17-24.


Isomer-specific comparisons of the hydrolysis of synthetic pyrethroids and their fluorogenic analogues by esterases from the cotton bollworm Helicoverpa armigera.

Yuan G, Li Y, Farnsworth CA, Coppin CW, Devonshire AL, Scott C, Russell RJ, Wu Y, Oakeshott JG.

Pestic Biochem Physiol. 2015 Jun;121:102-6. doi: 10.1016/j.pestbp.2014.12.010. Epub 2014 Dec 16.


Atmospheric hydrogen scavenging: from enzymes to ecosystems.

Greening C, Constant P, Hards K, Morales SE, Oakeshott JG, Russell RJ, Taylor MC, Berney M, Conrad R, Cook GM.

Appl Environ Microbiol. 2015 Feb;81(4):1190-9. Review.


Identification of candidate odorant degrading gene/enzyme systems in the antennal transcriptome of Drosophila melanogaster.

Younus F, Chertemps T, Pearce SL, Pandey G, Bozzolan F, Coppin CW, Russell RJ, Maïbèche-Coisne M, Oakeshott JG.

Insect Biochem Mol Biol. 2014 Oct;53:30-43. doi: 10.1016/j.ibmb.2014.07.003. Epub 2014 Jul 16.


300-Fold increase in production of the Zn2+-dependent dechlorinase TrzN in soluble form via apoenzyme stabilization.

Jackson CJ, Coppin CW, Carr PD, Aleksandrov A, Wilding M, Sugrue E, Ubels J, Paks M, Newman J, Peat TS, Russell RJ, Field M, Weik M, Oakeshott JG, Scott C.

Appl Environ Microbiol. 2014 Jul;80(13):4003-11. doi: 10.1128/AEM.00916-14. Epub 2014 Apr 25.


Traumatic brain injury recorded in the UK Joint Theatre Trauma Registry among the UK Armed Forces.

Hawley CA, de Burgh HT, Russell RJ, Mead A.

J Head Trauma Rehabil. 2015 Jan-Feb;30(1):E47-56. doi: 10.1097/HTR.0000000000000023.


A qualitative study of the use of the four quadrant approach to assist ethical decision-making during deployment.

Bernthal EM, Russell RJ, Draper HJ.

J R Army Med Corps. 2014 Jun;160(2):196-202. doi: 10.1136/jramc-2013-000214. Epub 2014 Jan 16.


Organophosphate and pyrethroid hydrolase activities of mutant Esterases from the cotton bollworm Helicoverpa armigera.

Li Y, Farnsworth CA, Coppin CW, Teese MG, Liu JW, Scott C, Zhang X, Russell RJ, Oakeshott JG.

PLoS One. 2013 Oct 29;8(10):e77685. doi: 10.1371/journal.pone.0077685. eCollection 2013.


Structural basis for a class of nanomolar influenza A neuraminidase inhibitors.

Kerry PS, Mohan S, Russell RJ, Bance N, Niikura M, Pinto BM.

Sci Rep. 2013 Oct 16;3:2871. doi: 10.1038/srep02871.


A safe, effective, and facility compatible cleaning in place procedure for affinity resin in large-scale monoclonal antibody purification.

Wang L, Dembecki J, Jaffe NE, O'Mara BW, Cai H, Sparks CN, Zhang J, Laino SG, Russell RJ, Wang M.

J Chromatogr A. 2013 Sep 20;1308:86-95. doi: 10.1016/j.chroma.2013.07.096. Epub 2013 Aug 1.


Hydrogen/deuterium exchange mass spectrometry for probing higher order structure of protein therapeutics: methodology and applications.

Wei H, Mo J, Tao L, Russell RJ, Tymiak AA, Chen G, Iacob RE, Engen JR.

Drug Discov Today. 2014 Jan;19(1):95-102. doi: 10.1016/j.drudis.2013.07.019. Epub 2013 Aug 6. Review.


Draft Genome Sequence of Pandoraea sp. Strain SD6-2, Isolated from Lindane-Contaminated Australian Soil.

Pushiri H, Pearce SL, Oakeshott JG, Russell RJ, Pandey G.

Genome Announc. 2013 Jul 5;1(4). pii: e00415-13. doi: 10.1128/genomeA.00415-13.


Draft Genome Sequence of Ralstonia sp. Strain GA3-3, Isolated from Australian Suburban Soil.

Pearce SL, Pushiri H, Oakeshott JG, Russell RJ, Pandey G.

Genome Announc. 2013 Jul 5;1(4). pii: e00414-13. doi: 10.1128/genomeA.00414-13.


Heterologous expression and biochemical characterisation of fourteen esterases from Helicoverpa armigera.

Teese MG, Farnsworth CA, Li Y, Coppin CW, Devonshire AL, Scott C, East P, Russell RJ, Oakeshott JG.

PLoS One. 2013 Jun 17;8(6):e65951. doi: 10.1371/journal.pone.0065951. Print 2013.


Functional screening of enzymes and bacteria for the dechlorination of hexachlorocyclohexane by a high-throughput colorimetric assay.

Sharma P, Jindal S, Bala K, Kumari K, Niharika N, Kaur J, Pandey G, Pandey R, Russell RJ, Oakeshott JG, Lal R.

Biodegradation. 2014 Apr;25(2):179-87. doi: 10.1007/s10532-013-9650-5. Epub 2013 Jun 6.


Structure and function of an insect α-carboxylesterase (αEsterase7) associated with insecticide resistance.

Jackson CJ, Liu JW, Carr PD, Younus F, Coppin C, Meirelles T, Lethier M, Pandey G, Ollis DL, Russell RJ, Weik M, Oakeshott JG.

Proc Natl Acad Sci U S A. 2013 Jun 18;110(25):10177-82. doi: 10.1073/pnas.1304097110. Epub 2013 Jun 3.


How many genetic options for evolving insecticide resistance in heliothine and spodopteran pests?

Oakeshott JG, Farnsworth CA, East PD, Scott C, Han Y, Wu Y, Russell RJ.

Pest Manag Sci. 2013 Aug;69(8):889-96. doi: 10.1002/ps.3542. Epub 2013 Jun 20. Review.


Soluble and membrane-bound Drosophila melanogaster CYP6G1 expressed in Escherichia coli: purification, activity, and binding properties toward multiple pesticides.

Cheesman MJ, Traylor MJ, Hilton ME, Richards KE, Taylor MC, Daborn PJ, Russell RJ, Gillam EM, Oakeshott JG.

Insect Biochem Mol Biol. 2013 May;43(5):455-65. doi: 10.1016/j.ibmb.2013.02.003. Epub 2013 Mar 5.


En-route care capability from point of injury impacts mortality after severe wartime injury.

Morrison JJ, Oh J, DuBose JJ, O'Reilly DJ, Russell RJ, Blackbourne LH, Midwinter MJ, Rasmussen TE.

Ann Surg. 2013 Feb;257(2):330-4. doi: 10.1097/SLA.0b013e31827eefcf.


Antiviral activity of Ecasol against feline calicivirus, a surrogate of human norovirus.

Chander Y, Johnson T, Goyal SM, Russell RJ.

J Infect Public Health. 2012 Dec;5(6):420-4. doi: 10.1016/j.jiph.2012.10.001. Epub 2012 Dec 17.


Cloning of a novel 6-chloronicotinic acid chlorohydrolase from the newly isolated 6-chloronicotinic acid mineralizing Bradyrhizobiaceae strain SG-6C.

Shettigar M, Pearce S, Pandey R, Khan F, Dorrian SJ, Balotra S, Russell RJ, Oakeshott JG, Pandey G.

PLoS One. 2012;7(11):e51162. doi: 10.1371/journal.pone.0051162. Epub 2012 Nov 30.


Characterization and identification of alanine to serine sequence variants in an IgG4 monoclonal antibody produced in mammalian cell lines.

Fu J, Bongers J, Tao L, Huang D, Ludwig R, Huang Y, Qian Y, Basch J, Goldstein J, Krishnan R, You L, Li ZJ, Russell RJ.

J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Nov 1;908:1-8. doi: 10.1016/j.jchromb.2012.09.023. Epub 2012 Sep 26.


Exploring the interactions of unsaturated glucuronides with influenza virus sialidase.

Bhatt B, Böhm R, Kerry PS, Dyason JC, Russell RJ, Thomson RJ, von Itzstein M.

J Med Chem. 2012 Oct 25;55(20):8963-8. doi: 10.1021/jm301145k. Epub 2012 Oct 11.


Contribution of NS1 effector domain dimerization to influenza A virus replication and virulence.

Ayllon J, Russell RJ, García-Sastre A, Hale BG.

J Virol. 2012 Dec;86(23):13095-8. doi: 10.1128/JVI.02237-12. Epub 2012 Sep 19.


Synthesis and evaluation of novel 3-C-alkylated-Neu5Ac2en derivatives as probes of influenza virus sialidase 150-loop flexibility.

Rudrawar S, Kerry PS, Rameix-Welti MA, Maggioni A, Dyason JC, Rose FJ, van der Werf S, Thomson RJ, Naffakh N, Russell RJ, von Itzstein M.

Org Biomol Chem. 2012 Nov 21;10(43):8628-39. doi: 10.1039/c2ob25627d.


Intramolecular epistasis and the evolution of a new enzymatic function.

Noor S, Taylor MC, Russell RJ, Jermiin LS, Jackson CJ, Oakeshott JG, Scott C.

PLoS One. 2012;7(6):e39822. doi: 10.1371/journal.pone.0039822. Epub 2012 Jun 29.


The pattern of paediatric trauma on operations.

Woods KL, Russell RJ, Bree S, Mahoney PF, McNicholas J.

J R Army Med Corps. 2012 Mar;158(1):34-7.


F420H2-dependent degradation of aflatoxin and other furanocoumarins is widespread throughout the actinomycetales.

Lapalikar GV, Taylor MC, Warden AC, Scott C, Russell RJ, Oakeshott JG.

PLoS One. 2012;7(2):e30114. doi: 10.1371/journal.pone.0030114. Epub 2012 Feb 27.


Control of bacterial contamination of washbasin taps and output water using Ecasol: a one-year study.

Boyle MA, O'Donnell MJ, Miller A, Russell RJ, Coleman DC.

J Hosp Infect. 2012 Apr;80(4):288-92. doi: 10.1016/j.jhin.2012.01.011. Epub 2012 Feb 29.


Glycine to glutamic acid misincorporation observed in a recombinant protein expressed by Escherichia coli cells.

Huang Y, O'Mara B, Conover M, Ludwig R, Fu J, Tao L, Li ZJ, Rieble S, Grace MJ, Russell RJ.

Protein Sci. 2012 May;21(5):625-32. doi: 10.1002/pro.2046. Epub 2012 Mar 16.


Testing the evolvability of an insect carboxylesterase for the detoxification of synthetic pyrethroid insecticides.

Coppin CW, Jackson CJ, Sutherland T, Hart PJ, Devonshire AL, Russell RJ, Oakeshott JG.

Insect Biochem Mol Biol. 2012 May;42(5):343-52. doi: 10.1016/j.ibmb.2012.01.004. Epub 2012 Jan 28.


Evaporative light scattering detection based HPLC method for the determination of polysorbate 80 in therapeutic protein formulations.

Nayak VS, Tan Z, Ihnat PM, Russell RJ, Grace MJ.

J Chromatogr Sci. 2012 Jan;50(1):21-5. doi: 10.1093/chromsci/bmr015.

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