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Items: 1 to 50 of 159

1.

The mutational landscape of Burkitt-like lymphoma with 11q aberration is distinct from that of Burkitt lymphoma.

Wagener R, Seufert J, Raimondi F, Bens S, Kleinheinz K, Nagel I, Altmüller J, Thiele H, Hübschmann D, Kohler CW, Nürnberg P, Au-Yeung R, Burkhardt B, Horn H, Leoncini L, Jaffe ES, Ott G, Rymkiewicz G, Schlesner M, Russell RB, Klapper W, Siebert R.

Blood. 2018 Dec 19. pii: blood-2018-07-864025. doi: 10.1182/blood-2018-07-864025. [Epub ahead of print]

PMID:
30567752
2.

Studying how genetic variants affect mechanism in biological systems.

Raimondi F, Russell RB.

Essays Biochem. 2018 Oct 26;62(4):575-582. doi: 10.1042/EBC20180021. Print 2018 Oct 26. Review.

PMID:
30315099
3.

Cancer genetics meets biomolecular mechanism-bridging an age-old gulf.

González-Sánchez JC, Raimondi F, Russell RB.

FEBS Lett. 2018 Feb;592(4):463-474. doi: 10.1002/1873-3468.12988. Epub 2018 Feb 8. Review.

4.

Landscape of nuclear transport receptor cargo specificity.

Mackmull MT, Klaus B, Heinze I, Chokkalingam M, Beyer A, Russell RB, Ori A, Beck M.

Mol Syst Biol. 2017 Dec 18;13(12):962. doi: 10.15252/msb.20177608.

5.

Cryptogenic cholestasis in young and adults: ATP8B1, ABCB11, ABCB4, and TJP2 gene variants analysis by high-throughput sequencing.

Vitale G, Gitto S, Raimondi F, Mattiaccio A, Mantovani V, Vukotic R, D'Errico A, Seri M, Russell RB, Andreone P.

J Gastroenterol. 2018 Aug;53(8):945-958. doi: 10.1007/s00535-017-1423-1. Epub 2017 Dec 13.

PMID:
29238877
6.

Genetic variants affecting equivalent protein family positions reflect human diversity.

Raimondi F, Betts MJ, Lu Q, Inoue A, Gutkind JS, Russell RB.

Sci Rep. 2017 Oct 6;7(1):12771. doi: 10.1038/s41598-017-12971-7.

7.

Capturing protein communities by structural proteomics in a thermophilic eukaryote.

Kastritis PL, O'Reilly FJ, Bock T, Li Y, Rogon MZ, Buczak K, Romanov N, Betts MJ, Bui KH, Hagen WJ, Hennrich ML, Mackmull MT, Rappsilber J, Russell RB, Bork P, Beck M, Gavin AC.

Mol Syst Biol. 2017 Jul 25;13(7):936. doi: 10.15252/msb.20167412.

8.

Corrigendum: Insights into cancer severity from biomolecular interaction mechanisms.

Raimondi F, Singh G, Betts MJ, Apic G, Vukotic R, Andreone P, Stein L, Russell RB.

Sci Rep. 2017 May 3;7:46284. doi: 10.1038/srep46284. No abstract available.

9.

Systematic identification of phosphorylation-mediated protein interaction switches.

Betts MJ, Wichmann O, Utz M, Andre T, Petsalaki E, Minguez P, Parca L, Roth FP, Gavin AC, Bork P, Russell RB.

PLoS Comput Biol. 2017 Mar 27;13(3):e1005462. doi: 10.1371/journal.pcbi.1005462. eCollection 2017 Mar.

10.

Association Between Infant Mortality Attributable to Birth Defects and Payment Source for Delivery - United States, 2011-2013.

Almli LM, Alter CC, Russell RB, Tinker SC, Howards PP, Cragan J, Petersen E, Carrino GE, Reefhuis J.

MMWR Morb Mortal Wkly Rep. 2017 Jan 27;66(3):84-87. doi: 10.15585/mmwr.mm6603a4.

11.

Insights into cancer severity from biomolecular interaction mechanisms.

Raimondi F, Singh G, Betts MJ, Apic G, Vukotic R, Andreone P, Stein L, Russell RB.

Sci Rep. 2016 Oct 4;6:34490. doi: 10.1038/srep34490. Erratum in: Sci Rep. 2017 May 03;7:46284.

12.

Mutagenesis of N-terminal residues of feline foamy virus Gag reveals entirely distinct functions during capsid formation, particle assembly, Gag processing and budding.

Liu Y, Betts MJ, Lei J, Wei G, Bao Q, Kehl T, Russell RB, Löchelt M.

Retrovirology. 2016 Aug 22;13(1):57. doi: 10.1186/s12977-016-0291-8.

13.

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

Boldt K, van Reeuwijk J, Lu Q, Koutroumpas K, Nguyen TM, Texier Y, van Beersum SE, Horn N, Willer JR, Mans DA, Dougherty G, Lamers IJ, Coene KL, Arts HH, Betts MJ, Beyer T, Bolat E, Gloeckner CJ, Haidari K, Hetterschijt L, Iaconis D, Jenkins D, Klose F, Knapp B, Latour B, Letteboer SJ, Marcelis CL, Mitic D, Morleo M, Oud MM, Riemersma M, Rix S, Terhal PA, Toedt G, van Dam TJ, de Vrieze E, Wissinger Y, Wu KM, Apic G, Beales PL, Blacque OE, Gibson TJ, Huynen MA, Katsanis N, Kremer H, Omran H, van Wijk E, Wolfrum U, Kepes F, Davis EE, Franco B, Giles RH, Ueffing M, Russell RB, Roepman R; UK10K Rare Diseases Group.

Nat Commun. 2016 May 13;7:11491. doi: 10.1038/ncomms11491.

14.

Genes encoding members of the JAK-STAT pathway or epigenetic regulators are recurrently mutated in T-cell prolymphocytic leukaemia.

López C, Bergmann AK, Paul U, Murga Penas EM, Nagel I, Betts MJ, Johansson P, Ritgen M, Baumann T, Aymerich M, Jayne S, Russell RB, Campo E, Dyer MJ, Dürig J, Siebert R.

Br J Haematol. 2016 Apr;173(2):265-73. doi: 10.1111/bjh.13952. Epub 2016 Feb 25.

PMID:
26917488
15.

KIAA0556 is a novel ciliary basal body component mutated in Joubert syndrome.

Sanders AA, de Vrieze E, Alazami AM, Alzahrani F, Malarkey EB, Sorusch N, Tebbe L, Kuhns S, van Dam TJ, Alhashem A, Tabarki B, Lu Q, Lambacher NJ, Kennedy JE, Bowie RV, Hetterschijt L, van Beersum S, van Reeuwijk J, Boldt K, Kremer H, Kesterson RA, Monies D, Abouelhoda M, Roepman R, Huynen MH, Ueffing M, Russell RB, Wolfrum U, Yoder BK, van Wijk E, Alkuraya FS, Blacque OE.

Genome Biol. 2015 Dec 29;16:293. doi: 10.1186/s13059-015-0858-z.

16.

DNA methylome analysis in Burkitt and follicular lymphomas identifies differentially methylated regions linked to somatic mutation and transcriptional control.

Kretzmer H, Bernhart SH, Wang W, Haake A, Weniger MA, Bergmann AK, Betts MJ, Carrillo-de-Santa-Pau E, Doose G, Gutwein J, Richter J, Hovestadt V, Huang B, Rico D, Jühling F, Kolarova J, Lu Q, Otto C, Wagener R, Arnolds J, Burkhardt B, Claviez A, Drexler HG, Eberth S, Eils R, Flicek P, Haas S, Humme M, Karsch D, Kerstens HHD, Klapper W, Kreuz M, Lawerenz C, Lenzek D, Loeffler M, López C, MacLeod RAF, Martens JHA, Kulis M, Martín-Subero JI, Möller P, Nage I, Picelli S, Vater I, Rohde M, Rosenstiel P, Rosolowski M, Russell RB, Schilhabel M, Schlesner M, Stadler PF, Szczepanowski M, Trümper L, Stunnenberg HG, Küppers R, Ammerpohl O, Lichter P, Siebert R, Hoffmann S, Radlwimmer B.

Nat Genet. 2015 Nov;47(11):1316-1325. doi: 10.1038/ng.3413. Epub 2015 Oct 5.

17.

The PCBP1 gene encoding poly(rC) binding protein I is recurrently mutated in Burkitt lymphoma.

Wagener R, Aukema SM, Schlesner M, Haake A, Burkhardt B, Claviez A, Drexler HG, Hummel M, Kreuz M, Loeffler M, Rosolowski M, López C, Möller P, Richter J, Rohde M, Betts MJ, Russell RB, Bernhart SH, Hoffmann S, Rosenstiel P, Schilhabel M, Szczepanowski M, Trümper L, Klapper W, Siebert R; ICGC MMML-Seq-Project; "Molecular Mechanisms in Malignant Lymphomas" Network Project of the Deutsche Krebshilfe.

Genes Chromosomes Cancer. 2015 Sep;54(9):555-64. doi: 10.1002/gcc.22268. Epub 2015 Jul 14.

PMID:
26173642
18.

Close to me: enhancing kangaroo care practice for NICU staff and parents.

Cooper L, Morrill A, Russell RB, Gooding JS, Miller L, Berns SD.

Adv Neonatal Care. 2014 Dec;14(6):410-23. doi: 10.1097/ANC.0000000000000144.

PMID:
25422927
19.

Mechismo: predicting the mechanistic impact of mutations and modifications on molecular interactions.

Betts MJ, Lu Q, Jiang Y, Drusko A, Wichmann O, Utz M, Valtierra-Gutiérrez IA, Schlesner M, Jaeger N, Jones DT, Pfister S, Lichter P, Eils R, Siebert R, Bork P, Apic G, Gavin AC, Russell RB.

Nucleic Acids Res. 2015 Jan;43(2):e10. doi: 10.1093/nar/gku1094. Epub 2014 Nov 11.

20.

Fighting for the next generation: US Prematurity in 2030.

McCabe ER, Carrino GE, Russell RB, Howse JL.

Pediatrics. 2014 Dec;134(6):1193-9. doi: 10.1542/peds.2014-2541. Epub 2014 Nov 3.

21.

Characterizing protein interactions employing a genome-wide siRNA cellular phenotyping screen.

Suratanee A, Schaefer MH, Betts MJ, Soons Z, Mannsperger H, Harder N, Oswald M, Gipp M, Ramminger E, Marcus G, Männer R, Rohr K, Wanker E, Russell RB, Andrade-Navarro MA, Eils R, König R.

PLoS Comput Biol. 2014 Sep 25;10(9):e1003814. doi: 10.1371/journal.pcbi.1003814. eCollection 2014 Sep.

22.

The mutational pattern of primary lymphoma of the central nervous system determined by whole-exome sequencing.

Vater I, Montesinos-Rongen M, Schlesner M, Haake A, Purschke F, Sprute R, Mettenmeyer N, Nazzal I, Nagel I, Gutwein J, Richter J, Buchhalter I, Russell RB, Wiestler OD, Eils R, Deckert M, Siebert R.

Leukemia. 2015 Mar;29(3):677-85. doi: 10.1038/leu.2014.264. Epub 2014 Sep 5.

PMID:
25189415
23.

SMARCA4-mutated atypical teratoid/rhabdoid tumors are associated with inherited germline alterations and poor prognosis.

Hasselblatt M, Nagel I, Oyen F, Bartelheim K, Russell RB, Schüller U, Junckerstorff R, Rosenblum M, Alassiri AH, Rossi S, Schmid I, Gottardo NG, Toledano H, Viscardi E, Balbin M, Witkowski L, Lu Q, Betts MJ, Foulkes WD, Siebert R, Frühwald MC, Schneppenheim R.

Acta Neuropathol. 2014 Sep;128(3):453-6. doi: 10.1007/s00401-014-1323-x. Epub 2014 Jul 25. No abstract available.

PMID:
25060813
24.

Recurrent RHOA mutations in pediatric Burkitt lymphoma treated according to the NHL-BFM protocols.

Rohde M, Richter J, Schlesner M, Betts MJ, Claviez A, Bonn BR, Zimmermann M, Damm-Welk C, Russell RB, Borkhardt A, Eils R, Hoell JI, Szczepanowski M, Oschlies I, Klapper W, Burkhardt B, Siebert R; German ICGC MMML-Seq-Project; NHL-BFM Study Group.

Genes Chromosomes Cancer. 2014 Nov;53(11):911-6. doi: 10.1002/gcc.22202. Epub 2014 Jul 8.

PMID:
25044415
25.

Recurrent mutation of JAK3 in T-cell prolymphocytic leukemia.

Bergmann AK, Schneppenheim S, Seifert M, Betts MJ, Haake A, Lopez C, Maria Murga Penas E, Vater I, Jayne S, Dyer MJ, Schrappe M, Dührsen U, Ammerpohl O, Russell RB, Küppers R, Dürig J, Siebert R.

Genes Chromosomes Cancer. 2014 Apr;53(4):309-16. doi: 10.1002/gcc.22141. Epub 2014 Jan 21.

PMID:
24446122
26.

A recurrent 11q aberration pattern characterizes a subset of MYC-negative high-grade B-cell lymphomas resembling Burkitt lymphoma.

Salaverria I, Martin-Guerrero I, Wagener R, Kreuz M, Kohler CW, Richter J, Pienkowska-Grela B, Adam P, Burkhardt B, Claviez A, Damm-Welk C, Drexler HG, Hummel M, Jaffe ES, Küppers R, Lefebvre C, Lisfeld J, Löffler M, Macleod RA, Nagel I, Oschlies I, Rosolowski M, Russell RB, Rymkiewicz G, Schindler D, Schlesner M, Scholtysik R, Schwaenen C, Spang R, Szczepanowski M, Trümper L, Vater I, Wessendorf S, Klapper W, Siebert R; Molecular Mechanisms in Malignant Lymphoma Network Project; Berlin-Frankfurt-Münster Non-Hodgkin Lymphoma Group.

Blood. 2014 Feb 20;123(8):1187-98. doi: 10.1182/blood-2013-06-507996. Epub 2014 Jan 7.

27.

Molecular dissection of human Argonaute proteins by DNA shuffling.

Schürmann N, Trabuco LG, Bender C, Russell RB, Grimm D.

Nat Struct Mol Biol. 2013 Jul;20(7):818-26. doi: 10.1038/nsmb.2607. Epub 2013 Jun 9.

PMID:
23748378
28.

Recurrent mutation of the ID3 gene in Burkitt lymphoma identified by integrated genome, exome and transcriptome sequencing.

Richter J, Schlesner M, Hoffmann S, Kreuz M, Leich E, Burkhardt B, Rosolowski M, Ammerpohl O, Wagener R, Bernhart SH, Lenze D, Szczepanowski M, Paulsen M, Lipinski S, Russell RB, Adam-Klages S, Apic G, Claviez A, Hasenclever D, Hovestadt V, Hornig N, Korbel JO, Kube D, Langenberger D, Lawerenz C, Lisfeld J, Meyer K, Picelli S, Pischimarov J, Radlwimmer B, Rausch T, Rohde M, Schilhabel M, Scholtysik R, Spang R, Trautmann H, Zenz T, Borkhardt A, Drexler HG, Möller P, MacLeod RA, Pott C, Schreiber S, Trümper L, Loeffler M, Stadler PF, Lichter P, Eils R, Küppers R, Hummel M, Klapper W, Rosenstiel P, Rosenwald A, Brors B, Siebert R; ICGC MMML-Seq Project.

Nat Genet. 2012 Dec;44(12):1316-20. doi: 10.1038/ng.2469. Epub 2012 Nov 11.

PMID:
23143595
29.

Negative protein-protein interaction datasets derived from large-scale two-hybrid experiments.

Trabuco LG, Betts MJ, Russell RB.

Methods. 2012 Dec;58(4):343-8. doi: 10.1016/j.ymeth.2012.07.028. Epub 2012 Aug 4.

PMID:
22884951
30.

Computational identification of novel amino-acid interactions in HIV Gag via correlated evolution.

Kalinina OV, Oberwinkler H, Glass B, Kräusslich HG, Russell RB, Briggs JA.

PLoS One. 2012;7(8):e42468. doi: 10.1371/journal.pone.0042468. Epub 2012 Aug 3.

31.

Dissecting the genomic complexity underlying medulloblastoma.

Jones DT, Jäger N, Kool M, Zichner T, Hutter B, Sultan M, Cho YJ, Pugh TJ, Hovestadt V, Stütz AM, Rausch T, Warnatz HJ, Ryzhova M, Bender S, Sturm D, Pleier S, Cin H, Pfaff E, Sieber L, Wittmann A, Remke M, Witt H, Hutter S, Tzaridis T, Weischenfeldt J, Raeder B, Avci M, Amstislavskiy V, Zapatka M, Weber UD, Wang Q, Lasitschka B, Bartholomae CC, Schmidt M, von Kalle C, Ast V, Lawerenz C, Eils J, Kabbe R, Benes V, van Sluis P, Koster J, Volckmann R, Shih D, Betts MJ, Russell RB, Coco S, Tonini GP, Schüller U, Hans V, Graf N, Kim YJ, Monoranu C, Roggendorf W, Unterberg A, Herold-Mende C, Milde T, Kulozik AE, von Deimling A, Witt O, Maass E, Rössler J, Ebinger M, Schuhmann MU, Frühwald MC, Hasselblatt M, Jabado N, Rutkowski S, von Bueren AO, Williamson D, Clifford SC, McCabe MG, Collins VP, Wolf S, Wiemann S, Lehrach H, Brors B, Scheurlen W, Felsberg J, Reifenberger G, Northcott PA, Taylor MD, Meyerson M, Pomeroy SL, Yaspo ML, Korbel JO, Korshunov A, Eils R, Pfister SM, Lichter P.

Nature. 2012 Aug 2;488(7409):100-5. doi: 10.1038/nature11284.

32.

The structure of proteins.

Lupas AN, Russell RB.

J Struct Biol. 2012 Sep;179(3):251. doi: 10.1016/j.jsb.2012.05.012. Epub 2012 May 26. No abstract available.

PMID:
22641090
33.

PepSite: prediction of peptide-binding sites from protein surfaces.

Trabuco LG, Lise S, Petsalaki E, Russell RB.

Nucleic Acids Res. 2012 Jul;40(Web Server issue):W423-7. doi: 10.1093/nar/gks398. Epub 2012 May 16.

34.

Topic pages: PLoS Computational Biology meets Wikipedia.

Wodak SJ, Mietchen D, Collings AM, Russell RB, Bourne PE.

PLoS Comput Biol. 2012;8(3):e1002446. doi: 10.1371/journal.pcbi.1002446. Epub 2012 Mar 29. No abstract available.

35.

Cross-talk between phosphorylation and lysine acetylation in a genome-reduced bacterium.

van Noort V, Seebacher J, Bader S, Mohammed S, Vonkova I, Betts MJ, Kühner S, Kumar R, Maier T, O'Flaherty M, Rybin V, Schmeisky A, Yus E, Stülke J, Serrano L, Russell RB, Heck AJ, Bork P, Gavin AC.

Mol Syst Biol. 2012 Feb 28;8:571. doi: 10.1038/msb.2012.4.

36.

ProtChemSI: a network of protein-chemical structural interactions.

Kalinina OV, Wichmann O, Apic G, Russell RB.

Nucleic Acids Res. 2012 Jan;40(Database issue):D549-53. doi: 10.1093/nar/gkr1049. Epub 2011 Nov 21.

37.

Content disputes in Wikipedia reflect geopolitical instability.

Apic G, Betts MJ, Russell RB.

PLoS One. 2011;6(6):e20902. doi: 10.1371/journal.pone.0020902. Epub 2011 Jun 22.

38.

Combinations of protein-chemical complex structures reveal new targets for established drugs.

Kalinina OV, Wichmann O, Apic G, Russell RB.

PLoS Comput Biol. 2011 May;7(5):e1002043. doi: 10.1371/journal.pcbi.1002043. Epub 2011 May 5.

39.

The three-dimensional molecular structure of the desmosomal plaque.

Al-Amoudi A, Castaño-Diez D, Devos DP, Russell RB, Johnson GT, Frangakis AS.

Proc Natl Acad Sci U S A. 2011 Apr 19;108(16):6480-5. doi: 10.1073/pnas.1019469108. Epub 2011 Apr 4.

40.

A systematic screen for protein-lipid interactions in Saccharomyces cerevisiae.

Gallego O, Betts MJ, Gvozdenovic-Jeremic J, Maeda K, Matetzki C, Aguilar-Gurrieri C, Beltran-Alvarez P, Bonn S, Fernández-Tornero C, Jensen LJ, Kuhn M, Trott J, Rybin V, Müller CW, Bork P, Kaksonen M, Russell RB, Gavin AC.

Mol Syst Biol. 2010 Nov 30;6:430. doi: 10.1038/msb.2010.87.

41.

Domain recombination: a workhorse for evolutionary innovation.

Apic G, Russell RB.

Sci Signal. 2010 Sep 14;3(139):pe30. doi: 10.1126/scisignal.3139pe30.

PMID:
20841565
42.

An automated stochastic approach to the identification of the protein specificity determinants and functional subfamilies.

Mazin PV, Gelfand MS, Mironov AA, Rakhmaninova AB, Rubinov AR, Russell RB, Kalinina OV.

Algorithms Mol Biol. 2010 Jul 15;5:29. doi: 10.1186/1748-7188-5-29.

43.

WD40 proteins propel cellular networks.

Stirnimann CU, Petsalaki E, Russell RB, Müller CW.

Trends Biochem Sci. 2010 Oct;35(10):565-74. doi: 10.1016/j.tibs.2010.04.003. Epub 2010 May 5. Review.

PMID:
20451393
44.

Modular architecture of nucleotide-binding pockets.

Gherardini PF, Ausiello G, Russell RB, Helmer-Citterich M.

Nucleic Acids Res. 2010 Jun;38(11):3809-16. doi: 10.1093/nar/gkq090. Epub 2010 Feb 25.

45.

Impact of genome reduction on bacterial metabolism and its regulation.

Yus E, Maier T, Michalodimitrakis K, van Noort V, Yamada T, Chen WH, Wodke JA, Güell M, Martínez S, Bourgeois R, Kühner S, Raineri E, Letunic I, Kalinina OV, Rode M, Herrmann R, Gutiérrez-Gallego R, Russell RB, Gavin AC, Bork P, Serrano L.

Science. 2009 Nov 27;326(5957):1263-8. doi: 10.1126/science.1177263.

46.

Proteome organization in a genome-reduced bacterium.

Kühner S, van Noort V, Betts MJ, Leo-Macias A, Batisse C, Rode M, Yamada T, Maier T, Bader S, Beltran-Alvarez P, Castaño-Diez D, Chen WH, Devos D, Güell M, Norambuena T, Racke I, Rybin V, Schmidt A, Yus E, Aebersold R, Herrmann R, Böttcher B, Frangakis AS, Russell RB, Serrano L, Bork P, Gavin AC.

Science. 2009 Nov 27;326(5957):1235-40. doi: 10.1126/science.1176343.

47.

A more structured metabolome.

Betts MJ, Russell RB.

Nat Struct Mol Biol. 2009 Nov;16(11):1125-6. doi: 10.1038/nsmb1109-1125. No abstract available.

PMID:
19888310
48.

Hb M Dothan [beta 25/26 (B7/B8)/(GGT/GAG-->GAG//Gly/Glu-->Glu]; a new mechanism of unstable methemoglobin variant and molecular characteristics.

Kutlar F, Hilliard LM, Zhuang L, Patel N, Eroglu B, Meiler SE, Carmichael H, Russell RB, Kutlar A.

Blood Cells Mol Dis. 2009 Nov-Dec;43(3):235-8. doi: 10.1016/j.bcmd.2009.08.006. Epub 2009 Sep 15.

PMID:
19758826
49.

Combining specificity determining and conserved residues improves functional site prediction.

Kalinina OV, Gelfand MS, Russell RB.

BMC Bioinformatics. 2009 Jun 9;10:174. doi: 10.1186/1471-2105-10-174.

50.

Accurate prediction of peptide binding sites on protein surfaces.

Petsalaki E, Stark A, García-Urdiales E, Russell RB.

PLoS Comput Biol. 2009 Mar;5(3):e1000335. doi: 10.1371/journal.pcbi.1000335. Epub 2009 Mar 27.

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