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Items: 1 to 50 of 235

1.

Exploitation of Synthetic mRNA To Drive Immune Effector Cell Recruitment and Functional Reprogramming In Vivo.

Xu Y, Huang L, Kirschman JL, Vanover DA, Tiwari PM, Santangelo PJ, Shen X, Russell DG.

J Immunol. 2019 Jan 15;202(2):608-617. doi: 10.4049/jimmunol.1800924. Epub 2018 Dec 12.

PMID:
30541883
2.

The Deconstructed Granuloma: A Complex High-Throughput Drug Screening Platform for the Discovery of Host-Directed Therapeutics Against Tuberculosis.

Huang L, Kushner NL, Theriault ME, Pisu D, Tan S, McNamara CW, Petrassi HM, Russell DG, Brown AC.

Front Cell Infect Microbiol. 2018 Aug 14;8:275. doi: 10.3389/fcimb.2018.00275. eCollection 2018.

3.

Enhanced Permeability and Retention-like Extravasation of Nanoparticles from the Vasculature into Tuberculosis Granulomas in Zebrafish and Mouse Models.

Fenaroli F, Repnik U, Xu Y, Johann K, Van Herck S, Dey P, Skjeldal FM, Frei DM, Bagherifam S, Kocere A, Haag R, De Geest BG, Barz M, Russell DG, Griffiths G.

ACS Nano. 2018 Aug 28;12(8):8646-8661. doi: 10.1021/acsnano.8b04433. Epub 2018 Aug 15.

PMID:
30081622
4.

Matrix metalloproteinase inhibitors enhance the efficacy of frontline drugs against Mycobacterium tuberculosis.

Xu Y, Wang L, Zimmerman MD, Chen KY, Huang L, Fu DJ, Kaya F, Rakhilin N, Nazarova EV, Bu P, Dartois V, Russell DG, Shen X.

PLoS Pathog. 2018 Apr 26;14(4):e1006974. doi: 10.1371/journal.ppat.1006974. eCollection 2018 Apr.

5.

Growth of Mycobacterium tuberculosis in vivo segregates with host macrophage metabolism and ontogeny.

Huang L, Nazarova EV, Tan S, Liu Y, Russell DG.

J Exp Med. 2018 Apr 2;215(4):1135-1152. doi: 10.1084/jem.20172020. Epub 2018 Mar 2.

6.

A Survey of the Public Perception of Chiropractic After Exposure to Chiropractic Public Place Marketing Events in New Zealand.

Russell DG, Glucina TT, Sherson MW, Bredin M.

J Chiropr Humanit. 2017 Mar 30;24(1):9-14. doi: 10.1016/j.echu.2017.02.001. eCollection 2017 Dec.

7.

HIV-associated disruption of lung cytokine networks is incompletely restored in asymptomatic HIV-infected Malawian adults on antiretroviral therapy.

Jambo KC, Tembo DL, Kamng'ona AW, Musicha P, Banda DH, Kankwatira AM, Malamba RD, Allain TJ, Heyderman RS, Russell DG, Mwandumba HC.

ERJ Open Res. 2017 Dec 14;3(4). pii: 00097-2017. doi: 10.1183/23120541.00097-2017. eCollection 2017 Oct.

8.

Alveolar T-helper 17 responses to streptococcus pneumoniae are preserved in ART-untreated and treated HIV-infected Malawian adults.

Peno C, Banda DH, Jambo N, Kankwatira AM, Malamba RD, Allain TJ, Ferreira DM, Heyderman RS, Russell DG, Mwandumba HC, Jambo KC.

J Infect. 2018 Feb;76(2):168-176. doi: 10.1016/j.jinf.2017.10.013. Epub 2017 Nov 29.

9.

Functional Analysis of Phagocyte Activity in Whole Blood from HIV/Tuberculosis-Infected Individuals Using a Novel Flow Cytometry-Based Assay.

Gupta-Wright A, Tembo D, Jambo KC, Chimbayo E, Mvaya L, Caldwell S, Russell DG, Mwandumba HC.

Front Immunol. 2017 Sep 28;8:1222. doi: 10.3389/fimmu.2017.01222. eCollection 2017.

10.

Host transcriptional responses following ex vivo re-challenge with Mycobacterium tuberculosis vary with disease status.

Yu EA, John SH, Tablante EC, King CA, Kenneth J, Russell DG, Mehta S.

PLoS One. 2017 Oct 4;12(10):e0185640. doi: 10.1371/journal.pone.0185640. eCollection 2017.

11.

Protective immunity against tuberculosis: what does it look like and how do we find it?

Huang L, Russell DG.

Curr Opin Immunol. 2017 Oct;48:44-50. doi: 10.1016/j.coi.2017.08.001. Epub 2017 Aug 18. Review.

12.

2-N-Arylthiazole inhibitors of Mycobacterium tuberculosis.

Clark MP, Wang T, Perola E, Deininger DD, Zuccola HJ, Jones SM, Gao H, VanderVen BC, Russell DG, Shoen CM, Cynamon MH, Thomson JA, Locher CP.

Bioorg Med Chem Lett. 2017 Sep 1;27(17):3987-3991. doi: 10.1016/j.bmcl.2017.07.067. Epub 2017 Jul 27.

PMID:
28778468
13.

Rv3723/LucA coordinates fatty acid and cholesterol uptake in Mycobacterium tuberculosis.

Nazarova EV, Montague CR, La T, Wilburn KM, Sukumar N, Lee W, Caldwell S, Russell DG, VanderVen BC.

Elife. 2017 Jun 27;6. pii: e26969. doi: 10.7554/eLife.26969.

14.

Correction: Mycobacterium tuberculosis arrests host cycle at the G1/S transition to establish long term infection.

Cumming BM, Rahman MA, Lamprecht DA, Rohde KH, Saini V, Adamson JH, Russell DG, Steyn AJC.

PLoS Pathog. 2017 Jul 14;13(7):e1006490. doi: 10.1371/journal.ppat.1006490. eCollection 2017 Jul.

15.

Microbiology: Diversity breeds tolerance.

Russell DG.

Nature. 2017 May 31;546(7656):44-45. doi: 10.1038/546044a. No abstract available.

PMID:
28569816
16.

Mycobacterium tuberculosis arrests host cycle at the G1/S transition to establish long term infection.

Cumming BM, Rahman MA, Lamprecht DA, Rohde KH, Saini V, Adamson JH, Russell DG, Steyn AJC.

PLoS Pathog. 2017 May 22;13(5):e1006389. doi: 10.1371/journal.ppat.1006389. eCollection 2017 May. Erratum in: PLoS Pathog. 2017 Jul 14;13(7):e1006490.

17.

Novel protein acetyltransferase, Rv2170, modulates carbon and energy metabolism in Mycobacterium tuberculosis.

Lee W, VanderVen BC, Walker S, Russell DG.

Sci Rep. 2017 Mar 6;7(1):72. doi: 10.1038/s41598-017-00067-1.

18.

The Minimal Unit of Infection: Mycobacterium tuberculosis in the Macrophage.

VanderVen BC, Huang L, Rohde KH, Russell DG.

Microbiol Spectr. 2016 Dec;4(6). doi: 10.1128/microbiolspec.TBTB2-0025-2016. Review.

19.

Pathogenic mycobacteria achieve cellular persistence by inhibiting the Niemann-Pick Type C disease cellular pathway.

Fineran P, Lloyd-Evans E, Lack NA, Platt N, Davis LC, Morgan AJ, Höglinger D, Tatituri RVV, Clark S, Williams IM, Tynan P, Al Eisa N, Nazarova E, Williams A, Galione A, Ory DS, Besra GS, Russell DG, Brenner MB, Sim E, Platt FM.

Wellcome Open Res. 2016 Nov 18;1:18. doi: 10.12688/wellcomeopenres.10036.2.

20.

A prospective survey of chiropractic student experiences with pediatric care and variability of case mix while on clinical placement in Rarotonga.

Todd AJ, Carroll MT, Russell DG, Mitchell EK.

J Chiropr Educ. 2017 Mar;31(1):14-19. doi: 10.7899/JCE-16-4. Epub 2016 Dec 14.

21.

MARCO variants are associated with phagocytosis, pulmonary tuberculosis susceptibility and Beijing lineage.

Thuong NT, Tram TT, Dinh TD, Thai PV, Heemskerk D, Bang ND, Chau TT, Russell DG, Thwaites GE, Hawn TR, Caws M, Dunstan SJ.

Genes Immun. 2016 Dec;17(7):419-425. doi: 10.1038/gene.2016.43. Epub 2016 Nov 17.

22.
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24.

Heterogeneous loss of HIV transcription and proviral DNA from 8E5/LAV lymphoblastic leukemia cells revealed by RNA FISH:FLOW analyses.

Wilburn KM, Mwandumba HC, Jambo KC, Boliar S, Solouki S, Russell DG, Gludish DW.

Retrovirology. 2016 Aug 11;13(1):55. doi: 10.1186/s12977-016-0289-2.

25.

The ins and outs of the Mycobacterium tuberculosis-containing vacuole.

Russell DG.

Cell Microbiol. 2016 Aug;18(8):1065-9. doi: 10.1111/cmi.12623. Epub 2016 Jun 27.

26.

Immune activation of the host cell induces drug tolerance in Mycobacterium tuberculosis both in vitro and in vivo.

Liu Y, Tan S, Huang L, Abramovitch RB, Rohde KH, Zimmerman MD, Chen C, Dartois V, VanderVen BC, Russell DG.

J Exp Med. 2016 May 2;213(5):809-25. doi: 10.1084/jem.20151248. Epub 2016 Apr 25.

27.

Changes in Quality of Life in 7 Older Adult Patients Receiving Activator Methods Chiropractic Technique.

Russell DG, Kimura MN, Cowie HR, de Groot CM, McMinn EA, Sherson MW.

J Chiropr Med. 2016 Mar;15(1):59-66. doi: 10.1016/j.jcm.2016.02.008. Epub 2016 Mar 25.

28.

The HIV-1 protein Vpr impairs phagosome maturation by controlling microtubule-dependent trafficking.

Dumas A, Lê-Bury G, Marie-Anaïs F, Herit F, Mazzolini J, Guilbert T, Bourdoncle P, Russell DG, Benichou S, Zahraoui A, Niedergang F.

J Cell Biol. 2015 Oct 26;211(2):359-72. doi: 10.1083/jcb.201503124.

29.

Chronic Household Air Pollution Exposure Is Associated with Impaired Alveolar Macrophage Function in Malawian Non-Smokers.

Rylance J, Chimpini C, Semple S, Russell DG, Jackson MJ, Heyderman RS, Gordon SB.

PLoS One. 2015 Sep 25;10(9):e0138762. doi: 10.1371/journal.pone.0138762. eCollection 2015.

30.

Perforin-2 is essential for intracellular defense of parenchymal cells and phagocytes against pathogenic bacteria.

McCormack RM, de Armas LR, Shiratsuchi M, Fiorentino DG, Olsson ML, Lichtenheld MG, Morales A, Lyapichev K, Gonzalez LE, Strbo N, Sukumar N, Stojadinovic O, Plano GV, Munson GP, Tomic-Canic M, Kirsner RS, Russell DG, Podack ER.

Elife. 2015 Sep 24;4. pii: e06508. doi: 10.7554/eLife.06508.

31.

Lesion-Specific Immune Response in Granulomas of Patients with Pulmonary Tuberculosis: A Pilot Study.

Subbian S, Tsenova L, Kim MJ, Wainwright HC, Visser A, Bandyopadhyay N, Bader JS, Karakousis PC, Murrmann GB, Bekker LG, Russell DG, Kaplan G.

PLoS One. 2015 Jul 2;10(7):e0132249. doi: 10.1371/journal.pone.0132249. eCollection 2015.

32.

Trans-species communication in the Mycobacterium tuberculosis-infected macrophage.

Tan S, Russell DG.

Immunol Rev. 2015 Mar;264(1):233-48. doi: 10.1111/imr.12254. Review.

33.

Novel inhibitors of cholesterol degradation in Mycobacterium tuberculosis reveal how the bacterium's metabolism is constrained by the intracellular environment.

VanderVen BC, Fahey RJ, Lee W, Liu Y, Abramovitch RB, Memmott C, Crowe AM, Eltis LD, Perola E, Deininger DD, Wang T, Locher CP, Russell DG.

PLoS Pathog. 2015 Feb 12;11(2):e1004679. doi: 10.1371/journal.ppat.1004679. eCollection 2015 Feb.

34.

Detection and quantification of microbial manipulation of phagosomal function.

Podinovskaia M, Russell DG.

Methods Cell Biol. 2015;126:305-29. doi: 10.1016/bs.mcb.2014.10.026. Epub 2015 Jan 14.

PMID:
25665452
35.

The Sculpting of the Mycobacterium tuberculosis Genome by Host Cell-Derived Pressures.

Russell DG, Lee W, Tan S, Sukumar N, Podinovskaia M, Fahey RJ, Vanderven BC.

Microbiol Spectr. 2014 Oct;2(5). doi: 10.1128/microbiolspec.MGM2-0016-2013. Review.

36.

Household air pollution causes dose-dependent inflammation and altered phagocytosis in human macrophages.

Rylance J, Fullerton DG, Scriven J, Aljurayyan AN, Mzinza D, Barrett S, Wright AK, Wootton DG, Glennie SJ, Baple K, Knott A, Mortimer K, Russell DG, Heyderman RS, Gordon SB.

Am J Respir Cell Mol Biol. 2015 May;52(5):584-93. doi: 10.1165/rcmb.2014-0188OC.

37.

Exploitation of Mycobacterium tuberculosis reporter strains to probe the impact of vaccination at sites of infection.

Sukumar N, Tan S, Aldridge BB, Russell DG.

PLoS Pathog. 2014 Sep 18;10(9):e1004394. doi: 10.1371/journal.ppat.1004394. eCollection 2014 Sep.

38.

Asymptomatic HIV-infected individuals on antiretroviral therapy exhibit impaired lung CD4(+) T-cell responses to mycobacteria.

Jambo KC, Banda DH, Afran L, Kankwatira AM, Malamba RD, Allain TJ, Gordon SB, Heyderman RS, Russell DG, Mwandumba HC.

Am J Respir Crit Care Med. 2014 Oct 15;190(8):938-47. doi: 10.1164/rccm.201405-0864OC.

39.

Temporary storage or permanent removal? The division of nitrogen between biotic assimilation and denitrification in stormwater biofiltration systems.

Payne EG, Fletcher TD, Russell DG, Grace MR, Cavagnaro TR, Evrard V, Deletic A, Hatt BE, Cook PL.

PLoS One. 2014 Mar 26;9(3):e90890. doi: 10.1371/journal.pone.0090890. eCollection 2014.

40.

Dynamic quantitative assays of phagosomal function.

Podinovskaia M, VanderVen BC, Yates RM, Glennie S, Fullerton D, Mwandumba HC, Russell DG.

Curr Protoc Immunol. 2013 Oct 1;102:Unit 14.34.. doi: 10.1002/0471142735.im1434s102.

41.

Small alveolar macrophages are infected preferentially by HIV and exhibit impaired phagocytic function.

Jambo KC, Banda DH, Kankwatira AM, Sukumar N, Allain TJ, Heyderman RS, Russell DG, Mwandumba HC.

Mucosal Immunol. 2014 Sep;7(5):1116-26. doi: 10.1038/mi.2013.127. Epub 2014 Jan 29.

42.

Trp'ing tuberculosis.

Russell DG.

Cell. 2013 Dec 5;155(6):1209-10. doi: 10.1016/j.cell.2013.11.015.

43.

Project on Elite Athlete Commitment (PEAK): IV. identification of new candidate commitment sources in the sport commitment model.

Scanlan TK, Russell DG, Scanlan LA, Klunchoo TJ, Chow GM.

J Sport Exerc Psychol. 2013 Oct;35(5):525-35.

PMID:
24197720
44.

Perspective: Graduation time.

Russell DG, Nathan CF.

Nature. 2013 Oct 10;502(7470):S7. doi: 10.1038/502S7a. No abstract available.

PMID:
24108080
45.

Defects in neutrophil granule mobilization and bactericidal activity in familial hemophagocytic lymphohistiocytosis type 5 (FHL-5) syndrome caused by STXBP2/Munc18-2 mutations.

Zhao XW, Gazendam RP, Drewniak A, van Houdt M, Tool AT, van Hamme JL, Kustiawan I, Meijer AB, Janssen H, Russell DG, van de Corput L, Tesselaar K, Boelens JJ, Kuhnle I, Van Der Werff Ten Bosch J, Kuijpers TW, van den Berg TK.

Blood. 2013 Jul 4;122(1):109-11. doi: 10.1182/blood-2013-03-494039. Epub 2013 May 17.

46.

Mycobacterium tuberculosis responds to chloride and pH as synergistic cues to the immune status of its host cell.

Tan S, Sukumar N, Abramovitch RB, Parish T, Russell DG.

PLoS Pathog. 2013;9(4):e1003282. doi: 10.1371/journal.ppat.1003282. Epub 2013 Apr 4.

47.

Intracellular Mycobacterium tuberculosis exploits host-derived fatty acids to limit metabolic stress.

Lee W, VanderVen BC, Fahey RJ, Russell DG.

J Biol Chem. 2013 Mar 8;288(10):6788-800. doi: 10.1074/jbc.M112.445056. Epub 2013 Jan 10.

48.

The evolutionary pressures that have molded Mycobacterium tuberculosis into an infectious adjuvant.

Russell DG.

Curr Opin Microbiol. 2013 Feb;16(1):78-84. doi: 10.1016/j.mib.2012.11.007. Epub 2013 Jan 3. Review.

49.

Mycobacterial trehalose dimycolate reprograms macrophage global gene expression and activates matrix metalloproteinases.

Sakamoto K, Kim MJ, Rhoades ER, Allavena RE, Ehrt S, Wainwright HC, Russell DG, Rohde KH.

Infect Immun. 2013 Mar;81(3):764-76. doi: 10.1128/IAI.00906-12. Epub 2012 Dec 21.

50.

Infection of macrophages with Mycobacterium tuberculosis induces global modifications to phagosomal function.

Podinovskaia M, Lee W, Caldwell S, Russell DG.

Cell Microbiol. 2013 Jun;15(6):843-59. doi: 10.1111/cmi.12092. Epub 2013 Jan 9.

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