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Squamous Cell Carcinoma of the Hand: A Retrospective Study in Immunosuppressed and Immunocompetent Individuals.

Mull JL, Phelan PS, Mull AB, Russell AJ, Hurst EA, Council ML.

Dermatol Surg. 2020 Feb 4. doi: 10.1097/DSS.0000000000002336. [Epub ahead of print]


A Semiautomated, Phenotypic, In Vitro Scratch Assay for Assessing Retinal Pigment Epithelial Cell Wound Healing.

Storm T, Wilson I, Campbell R, Bolinches-Amorós A, Russell AJ, Davies SG, Barnard AR, MacLaren RE.

J Ocul Pharmacol Ther. 2020 Feb 6. doi: 10.1089/jop.2019.0116. [Epub ahead of print]


Effects of a selective androgen receptor modulator (SARM), GSK2849466A, on stress urinary incontinence and bladder activity in rats with ovariectomy-induced oestrogen deficiency.

Kadekawa K, Kawamorita N, Shimizu T, Kurobe M, Turnbull PS, Chandra S, Kambara T, Barton JC, Russell AJ, Yoshimura N.

BJU Int. 2020 Feb 3. doi: 10.1111/bju.15022. [Epub ahead of print]


Tuning Butyrylcholinesterase Inactivation and Reactivation by Polymer-Based Protein Engineering.

Zhang L, Baker SL, Murata H, Harris N, Ji W, Amitai G, Matyjaszewski K, Russell AJ.

Adv Sci (Weinh). 2019 Nov 13;7(1):1901904. doi: 10.1002/advs.201901904. eCollection 2020 Jan.


Activated PI3Kδ breaches multiple B cell tolerance checkpoints and causes autoantibody production.

Lau A, Avery DT, Jackson K, Lenthall H, Volpi S, Brigden H, Russell AJ, Bier J, Reed JH, Smart JM, Cole T, Choo S, Gray PE, Berglund LJ, Hsu P, Wong M, O'Sullivan M, Boztug K, Meyts I, Uzel G, Notarangelo LD, Brink R, Goodnow CC, Tangye SG, Deenick EK.

J Exp Med. 2020 Feb 3;217(2). pii: e20191336. doi: 10.1084/jem.20191336.


Structure-function-dynamics of α-chymotrypsin based conjugates as a function of polymer charge.

Munasinghe A, Baker SL, Lin P, Russell AJ, Colina CM.

Soft Matter. 2020 Jan 2;16(2):456-465. doi: 10.1039/c9sm01842e.


Chemical Proteomics and Phenotypic Profiling Identifies the Aryl Hydrocarbon Receptor as a Molecular Target of the Utrophin Modulator Ezutromid.

Wilkinson IVL, Perkins KJ, Dugdale H, Moir L, Vuorinen A, Chatzopoulou M, Squire SE, Monecke S, Lomow A, Geese M, Charles PD, Burch P, Tinsley JM, Wynne GM, Davies SG, Wilson FX, Rastinejad F, Mohammed S, Davies KE, Russell AJ.

Angew Chem Int Ed Engl. 2020 Feb 3;59(6):2420-2428. doi: 10.1002/anie.201912392. Epub 2020 Jan 3.


Atom Transfer Radical Polymerization for Biorelated Hybrid Materials.

Baker SL, Kaupbayeva B, Lathwal S, Das SR, Russell AJ, Matyjaszewski K.

Biomacromolecules. 2019 Dec 9;20(12):4272-4298. doi: 10.1021/acs.biomac.9b01271. Epub 2019 Nov 18.


Characterisation of utrophin modulator SMT C1100 as a non-competitive inhibitor of firefly luciferase.

Wilkinson IVL, Reynolds JK, Galan SRG, Vuorinen A, Sills AJ, Pires E, Wynne GM, Wilson FX, Russell AJ.

Bioorg Chem. 2020 Jan;94:103395. doi: 10.1016/j.bioorg.2019.103395. Epub 2019 Oct 28.


Erythrocytes as carriers of immunoglobulin-based therapeutics.

Ji W, Smith PN, Koepsel RR, Andersen JD, Baker SL, Zhang L, Carmali S, Myerson JW, Muzykantov V, Russell AJ.

Acta Biomater. 2020 Jan 1;101:422-435. doi: 10.1016/j.actbio.2019.10.027. Epub 2019 Oct 25.


Transforming protein-polymer conjugate purification by tuning protein solubility.

Baker SL, Munasinghe A, Kaupbayeva B, Rebecca Kang N, Certiat M, Murata H, Matyjaszewski K, Lin P, Colina CM, Russell AJ.

Nat Commun. 2019 Oct 17;10(1):4718. doi: 10.1038/s41467-019-12612-9.


Isolation, Structural Identification, Synthesis, and Pharmacological Profiling of 1,2-trans-Dihydro-1,2-diol Metabolites of the Utrophin Modulator Ezutromid.

Chatzopoulou M, Claridge TDW, Davies KE, Davies SG, Elsey DJ, Emer E, Fletcher AM, Harriman S, Robinson N, Rowley JA, Russell AJ, Tinsley JM, Weaver R, Wilkinson IVL, Willis NJ, Wilson FX, Wynne GM.

J Med Chem. 2020 Mar 12;63(5):2547-2556. doi: 10.1021/acs.jmedchem.9b01547. Epub 2019 Oct 25.


A Biased Agonist at Immunometabolic Receptor GPR84 Causes Distinct Functional Effects in Macrophages.

Lucy D, Purvis GSD, Zeboudj L, Chatzopoulou M, Recio C, Bataille CJR, Wynne GM, Greaves DR, Russell AJ.

ACS Chem Biol. 2019 Sep 20;14(9):2055-2064. doi: 10.1021/acschembio.9b00533. Epub 2019 Sep 10.


The Malaria Cell Atlas: Single parasite transcriptomes across the complete Plasmodium life cycle.

Howick VM, Russell AJC, Andrews T, Heaton H, Reid AJ, Natarajan K, Butungi H, Metcalf T, Verzier LH, Rayner JC, Berriman M, Herren JK, Billker O, Hemberg M, Talman AM, Lawniczak MKN.

Science. 2019 Aug 23;365(6455). pii: eaaw2619. doi: 10.1126/science.aaw2619.


Clinical Importance of Myc Family Oncogene Aberrations in Epithelial Ovarian Cancer.

Jung M, Russell AJ, Kennedy C, Gifford AJ; Australian Ovarian Cancer Study Group, Mallitt KA, Sivarajasingam S, Bowtell DD, DeFazio A, Haber M, Norris MD, Henderson MJ.

JNCI Cancer Spectr. 2018 Nov 16;2(3):pky047. doi: 10.1093/jncics/pky047. eCollection 2018 Jul.


Self-reported motivations for offending by autistic sexual offenders.

Payne KL, Maras K, Russell AJ, Brosnan MJ.

Autism. 2020 Feb;24(2):307-320. doi: 10.1177/1362361319858860. Epub 2019 Jun 28.


Charge-Preserving Atom Transfer Radical Polymerization Initiator Rescues the Lost Function of Negatively Charged Protein-Polymer Conjugates.

Baker SL, Murata H, Kaupbayeva B, Tasbolat A, Matyjaszewski K, Russell AJ.

Biomacromolecules. 2019 Jun 10;20(6):2392-2405. doi: 10.1021/acs.biomac.9b00379. Epub 2019 May 22.


Inhibition of polyamine synthesis and uptake reduces tumor progression and prolongs survival in mouse models of neuroblastoma.

Gamble LD, Purgato S, Murray J, Xiao L, Yu DMT, Hanssen KM, Giorgi FM, Carter DR, Gifford AJ, Valli E, Milazzo G, Kamili A, Mayoh C, Liu B, Eden G, Sarraf S, Allan S, Di Giacomo S, Flemming CL, Russell AJ, Cheung BB, Oberthuer A, London WB, Fischer M, Trahair TN, Fletcher JI, Marshall GM, Ziegler DS, Hogarty MD, Burns MR, Perini G, Norris MD, Haber M.

Sci Transl Med. 2019 Jan 30;11(477). pii: eaau1099. doi: 10.1126/scitranslmed.aau1099.


Structure-based development of new RAS-effector inhibitors from a combination of active and inactive RAS-binding compounds.

Cruz-Migoni A, Canning P, Quevedo CE, Bataille CJR, Bery N, Miller A, Russell AJ, Phillips SEV, Carr SB, Rabbitts TH.

Proc Natl Acad Sci U S A. 2019 Feb 12;116(7):2545-2550. doi: 10.1073/pnas.1811360116. Epub 2019 Jan 25.


Can enzyme proximity accelerate cascade reactions?

Kuzmak A, Carmali S, von Lieres E, Russell AJ, Kondrat S.

Sci Rep. 2019 Jan 24;9(1):455. doi: 10.1038/s41598-018-37034-3.


Molecular Sieving on the Surface of a Nano-Armored Protein.

Kaupbayeva B, Murata H, Lucas A, Matyjaszewski K, Minden JS, Russell AJ.

Biomacromolecules. 2019 Mar 11;20(3):1235-1245. doi: 10.1021/acs.biomac.8b01651. Epub 2019 Feb 4.


Correction to: HIF prolyl hydroxylase inhibition protects skeletal muscle from eccentric contraction induced injury.

Billin AN, Honeycutt SE, McDougal AV, Kerr JP, Chen Z, Freudenberg JM, Rajpal DK, Luo G, Kramer HF, Geske RS, Fang F, Yao B, Clark RV, Lepore J, Cobitz A, Miller R, Nosaka K, Hinken AC, Russell AJ.

Skelet Muscle. 2018 Dec 10;8(1):38. doi: 10.1186/s13395-018-0185-7.


HIF prolyl hydroxylase inhibition protects skeletal muscle from eccentric contraction-induced injury.

Billin AN, Honeycutt SE, McDougal AV, Kerr JP, Chen Z, Freudenberg JM, Rajpal DK, Luo G, Kramer HF, Geske RS, Fang F, Yao B, Clark RV, Lepore J, Cobitz A, Miller R, Nosaka K, Hinken AC, Russell AJ.

Skelet Muscle. 2018 Nov 13;8(1):35. doi: 10.1186/s13395-018-0179-5. Erratum in: Skelet Muscle. 2018 Dec 10;8(1):38.


Biocatalytic "Oxygen-Fueled" Atom Transfer Radical Polymerization.

Enciso AE, Fu L, Lathwal S, Olszewski M, Wang Z, Das SR, Russell AJ, Matyjaszewski K.

Angew Chem Int Ed Engl. 2018 Dec 3;57(49):16157-16161. doi: 10.1002/anie.201809018. Epub 2018 Nov 8.


Adapting Psychological Therapies for Autism - Therapist Experience, Skills and Confidence.

Cooper K, Loades ME, Russell AJ.

Res Autism Spectr Disord. 2018 Jan 1;45:43-50. doi: 10.1016/j.rasd.2017.11.002.


Chemical Instability and Promiscuity of Arylmethylidenepyrazolinone-Based MDMX Inhibitors.

Stefaniak J, Lewis AM, Conole D, Galan SRG, Bataille CJR, Wynne GM, Castaldi MP, Lundbäck T, Russell AJ, Huber KVM.

ACS Chem Biol. 2018 Oct 19;13(10):2849-2854. doi: 10.1021/acschembio.8b00665. Epub 2018 Sep 19.


Tailoring Site Specificity of Bioconjugation Using Step-Wise Atom-Transfer Radical Polymerization on Proteins.

Carmali S, Murata H, Matyjaszewski K, Russell AJ.

Biomacromolecules. 2018 Oct 8;19(10):4044-4051. doi: 10.1021/acs.biomac.8b01064. Epub 2018 Sep 20.


Small molecule inhibitors of RAS-effector protein interactions derived using an intracellular antibody fragment.

Quevedo CE, Cruz-Migoni A, Bery N, Miller A, Tanaka T, Petch D, Bataille CJR, Lee LYW, Fallon PS, Tulmin H, Ehebauer MT, Fernandez-Fuentes N, Russell AJ, Carr SB, Phillips SEV, Rabbitts TH.

Nat Commun. 2018 Aug 9;9(1):3169. doi: 10.1038/s41467-018-05707-2.


Intramolecular Interactions of Conjugated Polymers Mimic Molecular Chaperones to Stabilize Protein-Polymer Conjugates.

Baker SL, Munasinghe A, Murata H, Lin P, Matyjaszewski K, Colina CM, Russell AJ.

Biomacromolecules. 2018 Sep 10;19(9):3798-3813. doi: 10.1021/acs.biomac.8b00927. Epub 2018 Aug 22.


The AMPK/p27Kip1 Axis Regulates Autophagy/Apoptosis Decisions in Aged Skeletal Muscle Stem Cells.

White JP, Billin AN, Campbell ME, Russell AJ, Huffman KM, Kraus WE.

Stem Cell Reports. 2018 Aug 14;11(2):425-439. doi: 10.1016/j.stemcr.2018.06.014. Epub 2018 Jul 19.


In vivo GDF3 administration abrogates aging related muscle regeneration delay following acute sterile injury.

Patsalos A, Simandi Z, Hays TT, Peloquin M, Hajian M, Restrepo I, Coen PM, Russell AJ, Nagy L.

Aging Cell. 2018 Oct;17(5):e12815. doi: 10.1111/acel.12815. Epub 2018 Jul 12.


2,4-Diaminothieno[3,2-d]pyrimidines, a new class of anthelmintic with activity against adult and egg stages of whipworm.

Partridge FA, Forman R, Willis NJ, Bataille CJR, Murphy EA, Brown AE, Heyer-Chauhan N, Marinič B, Sowood DJC, Wynne GM, Else KJ, Russell AJ, Sattelle DB.

PLoS Negl Trop Dis. 2018 Jul 11;12(7):e0006487. doi: 10.1371/journal.pntd.0006487. eCollection 2018 Jul.


Activation of the Immune-Metabolic Receptor GPR84 Enhances Inflammation and Phagocytosis in Macrophages.

Recio C, Lucy D, Purvis GSD, Iveson P, Zeboudj L, Iqbal AJ, Lin D, O'Callaghan C, Davison L, Griesbach E, Russell AJ, Wynne GM, Dib L, Monaco C, Greaves DR.

Front Immunol. 2018 Jun 20;9:1419. doi: 10.3389/fimmu.2018.01419. eCollection 2018.


Single-Cell (Multi)omics Technologies.

Chappell L, Russell AJC, Voet T.

Annu Rev Genomics Hum Genet. 2018 Aug 31;19:15-41. doi: 10.1146/annurev-genom-091416-035324. Epub 2018 May 4. Review.


Gender Identity in Autism: Sex Differences in Social Affiliation with Gender Groups.

Cooper K, Smith LGE, Russell AJ.

J Autism Dev Disord. 2018 Dec;48(12):3995-4006. doi: 10.1007/s10803-018-3590-1.


Molecular Profiling and Clonal Tracking of Secreted Rheumatoid Factors in Primary Sjögren's Syndrome.

Wang JJ, Reed JH, Colella AD, Russell AJ, Murray-Brown W, Chataway TK, Jackson KJL, Goodnow CC, Gordon TP.

Arthritis Rheumatol. 2018 Oct;70(10):1617-1625. doi: 10.1002/art.40539. Epub 2018 Aug 3.


Discovery of Tirasemtiv, the First Direct Fast Skeletal Muscle Troponin Activator.

Collibee SE, Bergnes G, Muci A, Browne WF 4th, Garard M, Hinken AC, Russell AJ, Suehiro I, Hartman J, Kawas R, Lu PP, Lee KH, Marquez D, Tomlinson M, Xu D, Kennedy A, Hwee D, Schaletzky J, Leung K, Malik FI, Morgans DJ Jr, Morgan BP.

ACS Med Chem Lett. 2018 Feb 13;9(4):354-358. doi: 10.1021/acsmedchemlett.7b00546. eCollection 2018 Apr 12.


Solid-phase synthesis of protein-polymers on reversible immobilization supports.

Murata H, Carmali S, Baker SL, Matyjaszewski K, Russell AJ.

Nat Commun. 2018 Feb 27;9(1):845. doi: 10.1038/s41467-018-03153-8.


Synthesis of Polymer Bioconjugates via Photoinduced Atom Transfer Radical Polymerization under Blue Light Irradiation.

Fu L, Wang Z, Lathwal S, Enciso AE, Simakova A, Das SR, Russell AJ, Matyjaszewski K.

ACS Macro Lett. 2018;7(10):1248-1253. doi: 10.1021/acsmacrolett.8b00609. Epub 2018 Sep 27.


Cognitive-behavioural therapy for adult attention-deficit hyperactivity disorder: a proof of concept randomised controlled trial.

Dittner AJ, Hodsoll J, Rimes KA, Russell AJ, Chalder T.

Acta Psychiatr Scand. 2018 Feb;137(2):125-137. doi: 10.1111/acps.12836. Epub 2017 Dec 27.


Simvastatin activates single skeletal RyR1 channels but exerts more complex regulation of the cardiac RyR2 isoform.

Venturi E, Lindsay C, Lotteau S, Yang Z, Steer E, Witschas K, Wilson AD, Wickens JR, Russell AJ, Steele D, Calaghan S, Sitsapesan R.

Br J Pharmacol. 2018 Mar;175(6):938-952. doi: 10.1111/bph.14136. Epub 2018 Feb 5.


A Breathing Atom-Transfer Radical Polymerization: Fully Oxygen-Tolerant Polymerization Inspired by Aerobic Respiration of Cells.

Enciso AE, Fu L, Russell AJ, Matyjaszewski K.

Angew Chem Int Ed Engl. 2018 Jan 22;57(4):933-936. doi: 10.1002/anie.201711105. Epub 2018 Jan 2.


An automated high-throughput system for phenotypic screening of chemical libraries on C. elegans and parasitic nematodes.

Partridge FA, Brown AE, Buckingham SD, Willis NJ, Wynne GM, Forman R, Else KJ, Morrison AA, Matthews JB, Russell AJ, Lomas DA, Sattelle DB.

Int J Parasitol Drugs Drug Resist. 2018 Apr;8(1):8-21. doi: 10.1016/j.ijpddr.2017.11.004. Epub 2017 Dec 2.


The Role of Metabolite-Sensing G Protein-Coupled Receptors in Inflammation and Metabolic Disease.

Recio C, Lucy D, Iveson P, Iqbal AJ, Valaris S, Wynne G, Russell AJ, Choudhury RP, O'Callaghan C, Monaco C, Greaves DR.

Antioxid Redox Signal. 2018 Jul 20;29(3):237-256. doi: 10.1089/ars.2017.7168. Epub 2018 Jan 17. Review.


Safety at The William Quarrier Scottish Epilepsy Centre.

Anderson J, Grant V, Elgammal M, Campbell A, Hampshire J, Hansen S, Russell AJC.

Seizure. 2017 Dec;53:10-12. doi: 10.1016/j.seizure.2017.10.003. Epub 2017 Oct 16.


Efficacy of a series of alpha-pyrone derivatives against Leishmania (L.) infantum and Trypanosoma cruzi.

Tempone AG, Ferreira DD, Lima ML, Costa Silva TA, Borborema SET, Reimão JQ, Galuppo MK, Guerra JM, Russell AJ, Wynne GM, Lai RYL, Cadelis MM, Copp BR.

Eur J Med Chem. 2017 Oct 20;139:947-960. doi: 10.1016/j.ejmech.2017.08.055. Epub 2017 Sep 1.


The William Quarrier Scottish Epilepsy Centre, Glasgow, Scotland.

Russell AJC, Anderson J, Razvi S, Oto M, Hill J, Gahagan G.

Epilepsy Behav. 2017 Nov;76S:S41-S45. doi: 10.1016/j.yebeh.2017.07.029. Epub 2017 Aug 31. No abstract available.


Probing Competitive and Co-operative Hydroxyl and Ammonium Hydrogen-Bonding Directed Epoxidations.

Brambilla M, Brennan MB, Csatayová K, Davies SG, Fletcher AM, Kennett AMR, Lee JA, Roberts PM, Russell AJ, Thomson JE.

J Org Chem. 2017 Oct 6;82(19):10297-10309. doi: 10.1021/acs.joc.7b01774. Epub 2017 Sep 19.


Bactericidal Specificity and Resistance Profile of Poly(Quaternary Ammonium) Polymers and Protein-Poly(Quaternary Ammonium) Conjugates.

Ji W, Koepsel RR, Murata H, Zadan S, Campbell AS, Russell AJ.

Biomacromolecules. 2017 Aug 14;18(8):2583-2593. doi: 10.1021/acs.biomac.7b00705. Epub 2017 Jul 14.


ATRP-grown protein-polymer conjugates containing phenylpiperazine selectively enhance transepithelial protein transport.

Cummings CS, Fein K, Murata H, Ball RL, Russell AJ, Whitehead KA.

J Control Release. 2017 Jun 10;255:270-278. doi: 10.1016/j.jconrel.2017.04.035. Epub 2017 Apr 25.


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