Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 268

1.

Urine collection methods for non-toilet-trained children in biological monitoring studies: Validation of a disposable diaper for characterization of tebuconazole exposure.

Oerlemans A, van Dael MFP, Vermeulen RCH, Russel FGM, Scheepers PTJ.

Toxicol Lett. 2018 Oct 4. pii: S0378-4274(18)31949-0. doi: 10.1016/j.toxlet.2018.09.018. [Epub ahead of print]

2.

Experimental study of diclofenac and its biliary metabolites on anastomotic healing.

Yauw STK, Lomme RMLM, van den Broek P, Greupink R, Russel FGM, van Goor H.

BJS Open. 2018 May 17;2(4):220-228. doi: 10.1002/bjs5.63. eCollection 2018 Aug.

3.

Screening of Drug-Transporter Interactions in a 3D Microfluidic Renal Proximal Tubule on a Chip.

Vriend J, Nieskens TTG, Vormann MK, van den Berge BT, van den Heuvel A, Russel FGM, Suter-Dick L, Lanz HL, Vulto P, Masereeuw R, Wilmer MJ.

AAPS J. 2018 Jul 26;20(5):87. doi: 10.1208/s12248-018-0247-0.

PMID:
30051196
4.

Disease-Associated Changes in Drug Transporters May Impact the Pharmacokinetics and/or Toxicity of Drugs: A White Paper From the International Transporter Consortium.

Evers R, Piquette-Miller M, Polli JW, Russel FGM, Sprowl JA, Tohyama K, Ware JA, de Wildt SN, Xie W, Brouwer KLR; International Transporter Consortium.

Clin Pharmacol Ther. 2018 May 14. doi: 10.1002/cpt.1115. [Epub ahead of print] Review.

PMID:
29756222
5.

Placental disposition of the immunosuppressive drug tacrolimus in renal transplant recipients and in ex vivo perfused placental tissue.

Freriksen JJM, Feyaerts D, van den Broek PHH, van der Heijden OWH, van Drongelen J, van Hamersvelt HW, Russel FGM, van der Molen RG, Greupink R.

Eur J Pharm Sci. 2018 Jul 1;119:244-248. doi: 10.1016/j.ejps.2018.04.017. Epub 2018 Apr 12.

6.

Corrigendum to 'Development of a mechanistic biokinetic model for hepatic bile acid handling to predict possible cholestatic effects of drugs' [European Journal of Pharmaceutical Sciences 115 (2018) 175-184].

Notenboom S, Weigand KM, Proost JH, van Lipzig MM, van de Steeg E, van den Broek PHH, Greupink R, Russel FGM, Groothuis GMM.

Eur J Pharm Sci. 2018 May 30;117:392-393. doi: 10.1016/j.ejps.2018.04.005. No abstract available.

PMID:
29650218
7.

A Mechanism-Based Population Pharmacokinetic Analysis Assessing the Feasibility of Efavirenz Dose Reduction to 400 mg in Pregnant Women.

Schalkwijk S, Ter Heine R, Colbers AC, Huitema ADR, Denti P, Dooley KE, Capparelli E, Best BM, Cressey TR, Greupink R, Russel FGM, Mirochnick M, Burger DM.

Clin Pharmacokinet. 2018 Nov;57(11):1421-1433. doi: 10.1007/s40262-018-0642-9.

PMID:
29520730
8.

Expression of Organic Anion Transporter 1 or 3 in Human Kidney Proximal Tubule Cells Reduces Cisplatin Sensitivity.

Nieskens TTG, Peters JGP, Dabaghie D, Korte D, Jansen K, Van Asbeck AH, Tavraz NN, Friedrich T, Russel FGM, Masereeuw R, Wilmer MJ.

Drug Metab Dispos. 2018 May;46(5):592-599. doi: 10.1124/dmd.117.079384. Epub 2018 Mar 7.

PMID:
29514829
9.

Development of a mechanistic biokinetic model for hepatic bile acid handling to predict possible cholestatic effects of drugs.

Notenboom S, Weigand KM, Proost JH, van Lipzig MMH, van de Steeg E, van den Broek PHH, Greupink R, Russel FGM, Groothuis GMM.

Eur J Pharm Sci. 2018 Mar 30;115:175-184. doi: 10.1016/j.ejps.2018.01.007. Epub 2018 Jan 5. Erratum in: Eur J Pharm Sci. 2018 May 30;117:392-393.

10.

Parenteral bilirubin in healthy volunteers: a reintroduction in translational research.

Dekker D, Dorresteijn MJ, Welzen MEB, Timman S, Pickkers P, Burger DM, Smits P, Wagener FADTG, Russel FGM.

Br J Clin Pharmacol. 2018 Feb;84(2):268-279. doi: 10.1111/bcp.13458. Epub 2017 Dec 15.

PMID:
29068066
11.

Proguanil and cycloguanil are organic cation transporter and multidrug and toxin extrusion substrates.

van der Velden M, Bilos A, van den Heuvel JJMW, Rijpma SR, Hurkmans EGE, Sauerwein RW, Russel FGM, Koenderink JB.

Malar J. 2017 Oct 23;16(1):422. doi: 10.1186/s12936-017-2062-y.

12.

Statins Affect Skeletal Muscle Performance: Evidence for Disturbances in Energy Metabolism.

Allard NAE, Schirris TJJ, Verheggen RJ, Russel FGM, Rodenburg RJ, Smeitink JAM, Thompson PD, Hopman MTE, Timmers S.

J Clin Endocrinol Metab. 2018 Jan 1;103(1):75-84. doi: 10.1210/jc.2017-01561.

PMID:
29040646
13.

Therapeutic effects of the mitochondrial ROS-redox modulator KH176 in a mammalian model of Leigh Disease.

de Haas R, Das D, Garanto A, Renkema HG, Greupink R, van den Broek P, Pertijs J, Collin RWJ, Willems P, Beyrath J, Heerschap A, Russel FG, Smeitink JA.

Sci Rep. 2017 Sep 15;7(1):11733. doi: 10.1038/s41598-017-09417-5.

14.

Mild intracellular acidification by dexamethasone attenuates mitochondrial dysfunction in a human inflammatory proximal tubule epithelial cell model.

Schirris TJJ, Jansen J, Mihajlovic M, van den Heuvel LP, Masereeuw R, Russel FGM.

Sci Rep. 2017 Sep 6;7(1):10623. doi: 10.1038/s41598-017-10483-y.

15.

Prediction of Fetal Darunavir Exposure by Integrating Human Ex-Vivo Placental Transfer and Physiologically Based Pharmacokinetic Modeling.

Schalkwijk S, Buaben AO, Freriksen JJM, Colbers AP, Burger DM, Greupink R, Russel FGM.

Clin Pharmacokinet. 2018 Jun;57(6):705-716. doi: 10.1007/s40262-017-0583-8.

16.

Flucloxacillin Results in Suboptimal Plasma Voriconazole Concentrations.

Muilwijk EW, Dekkers BGJ, Henriet SSV, Verweij PE, Witjes B, Lashof AMLO, Groeneveld GH, van der Hoeven J, Alffenaar JWC, Russel FGM, van de Veerdonk F, Brüggemann RJM.

Antimicrob Agents Chemother. 2017 Aug 24;61(9). pii: e00915-17. doi: 10.1128/AAC.00915-17. Print 2017 Sep.

17.

The Role of Efflux Pumps in Tuberculosis Treatment and Their Promise as a Target in Drug Development: Unraveling the Black Box.

Te Brake LHM, de Knegt GJ, de Steenwinkel JE, van Dam TJP, Burger DM, Russel FGM, van Crevel R, Koenderink JB, Aarnoutse RE.

Annu Rev Pharmacol Toxicol. 2018 Jan 6;58:271-291. doi: 10.1146/annurev-pharmtox-010617-052438. Epub 2017 Jul 17.

PMID:
28715978
18.

Editor's Highlight: PlacentalDisposition and Effects of Crizotinib: An Ex Vivo Study in the Isolated Dual-Side Perfused Human Cotyledon.

Eliesen GAM, van den Broek P, van den Heuvel JJ, Bilos A, Pertijs J, van Drongelen J, Russel FGM, Greupink R.

Toxicol Sci. 2017 Jun 1;157(2):500-509. doi: 10.1093/toxsci/kfx063.

PMID:
28369651
19.

Uremic Solutes in Chronic Kidney Disease and Their Role in Progression.

van den Brand JA, Mutsaers HA, van Zuilen AD, Blankestijn PJ, van den Broek PH, Russel FG, Masereeuw R, Wetzels JF.

PLoS One. 2016 Dec 29;11(12):e0168117. doi: 10.1371/journal.pone.0168117. eCollection 2016.

20.

Effects of a human recombinant alkaline phosphatase during impaired mitochondrial function in human renal proximal tubule epithelial cells.

Peters E, Schirris T, van Asbeck AH, Gerretsen J, Eymael J, Ashikov A, Adjobo-Hermans MJ, Russel F, Pickkers P, Masereeuw R.

Eur J Pharmacol. 2017 Feb 5;796:149-157. doi: 10.1016/j.ejphar.2016.12.034. Epub 2016 Dec 22.

PMID:
28012971
21.

Moxifloxacin Is a Potent In Vitro Inhibitor of OCT- and MATE-Mediated Transport of Metformin and Ethambutol.

Te Brake LH, van den Heuvel JJ, Buaben AO, van Crevel R, Bilos A, Russel FG, Aarnoutse RE, Koenderink JB.

Antimicrob Agents Chemother. 2016 Nov 21;60(12):7105-7114. Print 2016 Dec.

22.

Cathepsin L is crucial for the development of early experimental diabetic nephropathy.

Garsen M, Rops AL, Dijkman H, Willemsen B, van Kuppevelt TH, Russel FG, Rabelink TJ, Berden JH, Reinheckel T, van der Vlag J.

Kidney Int. 2016 Nov;90(5):1012-1022. doi: 10.1016/j.kint.2016.06.035. Epub 2016 Aug 26.

PMID:
27575559
23.

Substantially lowered dolutegravir exposure in a treatment-experienced perinatally HIV-1-infected pregnant woman.

Schalkwijk S, Feiterna-Sperling C, Weizsäcker K, Colbers A, Bührer C, Greupink R, Russel FG, Burger D; PANNA network.

AIDS. 2016 Jul 31;30(12):1999-2001. doi: 10.1097/QAD.0000000000001123. No abstract available.

PMID:
27428578
24.

Protective Efficacy Induced by Genetically Attenuated Mid-to-Late Liver-Stage Arresting Plasmodium berghei Δmrp2 Parasites.

van der Velden M, Rijpma SR, Verweij V, van Gemert GJ, Chevalley-Maurel S, van de Vegte-Bolmer M, Franke-Fayard BM, Russel FG, Janse CJ, Sauerwein RW, Koenderink JB.

Am J Trop Med Hyg. 2016 Aug 3;95(2):378-82. doi: 10.4269/ajtmh.16-0226. Epub 2016 Jun 13.

25.

Anemia, Micronutrient Deficiencies, and Malaria in Children and Women in Sierra Leone Prior to the Ebola Outbreak - Findings of a Cross-Sectional Study.

Wirth JP, Rohner F, Woodruff BA, Chiwile F, Yankson H, Koroma AS, Russel F, Sesay F, Dominguez E, Petry N, Shahab-Ferdows S, de Onis M, Hodges MH.

PLoS One. 2016 May 10;11(5):e0155031. doi: 10.1371/journal.pone.0155031. eCollection 2016.

26.

Inhibitory Potential of Antifungal Drugs on ATP-Binding Cassette Transporters P-Glycoprotein, MRP1 to MRP5, BCRP, and BSEP.

Lempers VJ, van den Heuvel JJ, Russel FG, Aarnoutse RE, Burger DM, Brüggemann RJ, Koenderink JB.

Antimicrob Agents Chemother. 2016 May 23;60(6):3372-9. doi: 10.1128/AAC.02931-15. Print 2016 Jun.

27.

Vital and dispensable roles of Plasmodium multidrug resistance transporters during blood- and mosquito-stage development.

Rijpma SR, van der Velden M, Annoura T, Matz JM, Kenthirapalan S, Kooij TW, Matuschewski K, van Gemert GJ, van de Vegte-Bolmer M, Siebelink-Stoter R, Graumans W, Ramesar J, Klop O, Russel FG, Sauerwein RW, Janse CJ, Franke-Fayard BM, Koenderink JB.

Mol Microbiol. 2016 Jul;101(1):78-91. doi: 10.1111/mmi.13373. Epub 2016 May 23.

28.

The effect of dipyridamole on the pharmacokinetics of metformin: a randomized crossover study in healthy volunteers.

El Messaoudi S, Russel FG, Colbers A, Bandell CC, van den Broek PH, Burger DM, Rongen GA, Riksen NP.

Eur J Clin Pharmacol. 2016 Jun;72(6):725-30. doi: 10.1007/s00228-016-2039-8. Epub 2016 Mar 15.

29.

First reported use of elvitegravir and cobicistat during pregnancy.

Schalkwijk S, Colbers A, Konopnicki D, Greupink R, Russel FG, Burger D; PANNA network.

AIDS. 2016 Mar 13;30(5):807-8. doi: 10.1097/QAD.0000000000000976. No abstract available.

PMID:
26913711
30.

MRP1 mediates folate transport and antifolate sensitivity in Plasmodium falciparum.

Rijpma SR, van der Velden M, Bilos A, Jansen RS, Mahakena S, Russel FG, Sauerwein RW, van de Wetering K, Koenderink JB.

FEBS Lett. 2016 Feb;590(4):482-92. doi: 10.1002/1873-3468.12079. Epub 2016 Feb 17.

31.

Heterogeneous transport of digitalis-like compounds by P-glycoprotein in vesicular and cellular assays.

Gozalpour E, Wilmer MJ, Bilos A, Masereeuw R, Russel FG, Koenderink JB.

Toxicol In Vitro. 2016 Apr;32:138-45. doi: 10.1016/j.tiv.2015.12.009. Epub 2015 Dec 17.

PMID:
26708294
32.

Inhibitory potential of tuberculosis drugs on ATP-binding cassette drug transporters.

Te Brake LH, Russel FG, van den Heuvel JJ, de Knegt GJ, de Steenwinkel JE, Burger DM, Aarnoutse RE, Koenderink JB.

Tuberculosis (Edinb). 2016 Jan;96:150-7. doi: 10.1016/j.tube.2015.08.004. Epub 2015 Oct 9.

PMID:
26682943
33.

Feline hepatic biotransformation of diazepam: Differences between cats and dogs.

van Beusekom CD, van den Heuvel JJ, Koenderink JB, Russel FG, Schrickx JA.

Res Vet Sci. 2015 Dec;103:119-25. doi: 10.1016/j.rvsc.2015.09.016. Epub 2015 Sep 25.

PMID:
26679806
34.

Placental transfer of the HIV integrase inhibitor dolutegravir in an ex vivo human cotyledon perfusion model.

Schalkwijk S, Greupink R, Colbers AP, Wouterse AC, Verweij VG, van Drongelen J, Teulen M, van den Oetelaar D, Burger DM, Russel FG.

J Antimicrob Chemother. 2016 Feb;71(2):480-3. doi: 10.1093/jac/dkv358. Epub 2015 Nov 3.

PMID:
26538508
35.

Mitoenergetic Dysfunction Triggers a Rapid Compensatory Increase in Steady-State Glucose Flux.

Liemburg-Apers DC, Schirris TJ, Russel FG, Willems PH, Koopman WJ.

Biophys J. 2015 Oct 6;109(7):1372-86. doi: 10.1016/j.bpj.2015.08.002.

36.

Mitochondrial ADP/ATP exchange inhibition: a novel off-target mechanism underlying ibipinabant-induced myotoxicity.

Schirris TJ, Ritschel T, Herma Renkema G, Willems PH, Smeitink JA, Russel FG.

Sci Rep. 2015 Sep 29;5:14533. doi: 10.1038/srep14533.

37.

Statin Lactonization by Uridine 5'-Diphospho-glucuronosyltransferases (UGTs).

Schirris TJ, Ritschel T, Bilos A, Smeitink JA, Russel FG.

Mol Pharm. 2015 Nov 2;12(11):4048-55. doi: 10.1021/acs.molpharmaceut.5b00474. Epub 2015 Oct 6.

PMID:
26412035
38.

Physiologically Based Modelling of Darunavir/Ritonavir Pharmacokinetics During Pregnancy.

Colbers A, Greupink R, Litjens C, Burger D, Russel FG.

Clin Pharmacokinet. 2016 Mar;55(3):381-96. doi: 10.1007/s40262-015-0325-8.

39.

Gait analysis in a mouse model resembling Leigh disease.

de Haas R, Russel FG, Smeitink JA.

Behav Brain Res. 2016 Jan 1;296:191-198. doi: 10.1016/j.bbr.2015.09.006. Epub 2015 Sep 9.

PMID:
26363424
40.

Multidrug ATP-binding cassette transporters are essential for hepatic development of Plasmodium sporozoites.

Rijpma SR, van der Velden M, González-Pons M, Annoura T, van Schaijk BC, van Gemert GJ, van den Heuvel JJ, Ramesar J, Chevalley-Maurel S, Ploemen IH, Khan SM, Franetich JF, Mazier D, de Wilt JH, Serrano AE, Russel FG, Janse CJ, Sauerwein RW, Koenderink JB, Franke-Fayard BM.

Cell Microbiol. 2016 Mar;18(3):369-83. doi: 10.1111/cmi.12517. Epub 2015 Nov 10.

41.

Statin-Induced Myopathy Is Associated with Mitochondrial Complex III Inhibition.

Schirris TJ, Renkema GH, Ritschel T, Voermans NC, Bilos A, van Engelen BG, Brandt U, Koopman WJ, Beyrath JD, Rodenburg RJ, Willems PH, Smeitink JA, Russel FG.

Cell Metab. 2015 Sep 1;22(3):399-407. doi: 10.1016/j.cmet.2015.08.002.

42.

Salvia Miltiorrhiza Root Water-Extract (Danshen) Has No Beneficial Effect on Cardiovascular Risk Factors. A Randomized Double-Blind Cross-Over Trial.

van Poppel PC, Breedveld P, Abbink EJ, Roelofs H, van Heerde W, Smits P, Lin W, Tan AH, Russel FG, Donders R, Tack CJ, Rongen GA.

PLoS One. 2015 Jul 20;10(7):e0128695. doi: 10.1371/journal.pone.0128695. eCollection 2015.

43.

PfMDR2 and PfMDR5 are dispensable for Plasmodium falciparum asexual parasite multiplication but change in vitro susceptibility to anti-malarial drugs.

van der Velden M, Rijpma SR, Russel FG, Sauerwein RW, Koenderink JB.

Malar J. 2015 Feb 14;14:76. doi: 10.1186/s12936-015-0581-y.

44.

Exposure to total and protein-unbound rifampin is not affected by malnutrition in Indonesian tuberculosis patients.

te Brake LH, Ruslami R, Later-Nijland H, Mooren F, Teulen M, Apriani L, Koenderink JB, Russel FG, Burger DM, Alisjahbana B, Wieringa F, van Crevel R, Aarnoutse RE.

Antimicrob Agents Chemother. 2015;59(6):3233-9. doi: 10.1128/AAC.03485-14. Epub 2015 Mar 23.

45.

Including carrier-mediated transport in oral uptake prediction of nutrients and pharmaceuticals in humans.

O'Connor IA, Veltman K, Huijbregts MA, Ragas AM, Russel FG, Hendriks AJ.

Environ Toxicol Pharmacol. 2014 Nov;38(3):938-47. doi: 10.1016/j.etap.2014.10.007. Epub 2014 Oct 22.

PMID:
25461554
46.

Aggregate dermal exposure to cyclic siloxanes in personal care products: implications for risk assessment.

Biesterbos JW, Beckmann G, van Wel L, Anzion RB, von Goetz N, Dudzina T, Roeleveld N, Ragas AM, Russel FG, Scheepers PT.

Environ Int. 2015 Jan;74:231-9. doi: 10.1016/j.envint.2014.10.017. Epub 2014 Nov 5.

PMID:
25454240
47.

Na(+),K(+)-ATPase isoform selectivity for digitalis-like compounds is determined by two amino acids in the first extracellular loop.

Weigand KM, Laursen M, Swarts HG, Engwerda AH, Prüfert C, Sandrock J, Nissen P, Fedosova NU, Russel FG, Koenderink JB.

Chem Res Toxicol. 2014 Dec 15;27(12):2082-92. doi: 10.1021/tx500290k. Epub 2014 Nov 12.

PMID:
25361285
48.

Multidrug resistance protein 4/ ATP binding cassette transporter 4: a new potential therapeutic target for acute myeloid leukemia.

Copsel S, Bruzzone A, May M, Beyrath J, Wargon V, Cany J, Russel FG, Shayo C, Davio C.

Oncotarget. 2014 Oct 15;5(19):9308-21.

49.

Convallatoxin: a new P-glycoprotein substrate.

Gozalpour E, Greupink R, Bilos A, Verweij V, van den Heuvel JJ, Masereeuw R, Russel FG, Koenderink JB.

Eur J Pharmacol. 2014 Dec 5;744:18-27. doi: 10.1016/j.ejphar.2014.09.031. Epub 2014 Sep 28.

PMID:
25264938
50.

Application of urine proteomics for biomarker discovery in drug-induced liver injury.

van Swelm RP, Kramers C, Masereeuw R, Russel FG.

Crit Rev Toxicol. 2014 Nov;44(10):823-41. doi: 10.3109/10408444.2014.931341. Epub 2014 Sep 29. Review.

PMID:
25264586

Supplemental Content

Loading ...
Support Center