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Items: 20

1.

Neuropathy-related mutations alter the membrane binding properties of the human myelin protein P0 cytoplasmic tail.

Raasakka A, Ruskamo S, Barker R, Krokengen OC, Vatne GH, Kristiansen CK, Hallin EI, Skoda MWA, Bergmann U, Wacklin-Knecht H, Jones NC, Hoffmann SV, Kursula P.

PLoS One. 2019 Jun 7;14(6):e0216833. doi: 10.1371/journal.pone.0216833. eCollection 2019.

2.

Molecular structure and function of myelin protein P0 in membrane stacking.

Raasakka A, Ruskamo S, Kowal J, Han H, Baumann A, Myllykoski M, Fasano A, Rossano R, Riccio P, Bürck J, Ulrich AS, Stahlberg H, Kursula P.

Sci Rep. 2019 Jan 24;9(1):642. doi: 10.1038/s41598-018-37009-4.

3.

The N-terminal domain of unknown function (DUF959) in collagen XVIII is intrinsically disordered and highly O-glycosylated.

Kaur I, Ruskamo S, Koivunen J, Heljasvaara R, Lackman JJ, Izzi V, Petäjä-Repo UE, Kursula P, Pihlajaniemi T.

Biochem J. 2018 Nov 20;475(22):3577-3593. doi: 10.1042/BCJ20180405.

PMID:
30327321
4.

Structure and dynamics of a human myelin protein P2 portal region mutant indicate opening of the β barrel in fatty acid binding proteins.

Laulumaa S, Nieminen T, Raasakka A, Krokengen OC, Safaryan A, Hallin EI, Brysbaert G, Lensink MF, Ruskamo S, Vattulainen I, Kursula P.

BMC Struct Biol. 2018 Jun 25;18(1):8. doi: 10.1186/s12900-018-0087-2.

5.

Structural basis for PDZ domain interactions in the post-synaptic density scaffolding protein Shank3.

Ponna SK, Ruskamo S, Myllykoski M, Keller C, Boeckers TM, Kursula P.

J Neurochem. 2018 Jun;145(6):449-463. doi: 10.1111/jnc.14322. Epub 2018 Jun 10.

6.

Publisher Correction: Molecular mechanisms of Charcot-Marie-Tooth neuropathy linked to mutations in human myelin protein P2.

Ruskamo S, Nieminen T, Kristiansen CK, Vatne GH, Baumann A, Hallin EI, Raasakka A, Joensuu P, Bergmann U, Vattulainen I, Kursula P.

Sci Rep. 2018 Jan 8;8(1):517. doi: 10.1038/s41598-017-18751-7.

7.

Molecular mechanisms of Charcot-Marie-Tooth neuropathy linked to mutations in human myelin protein P2.

Ruskamo S, Nieminen T, Kristiansen CK, Vatne GH, Baumann A, Hallin EI, Raasakka A, Joensuu P, Bergmann U, Vattulainen I, Kursula P.

Sci Rep. 2017 Jul 26;7(1):6510. doi: 10.1038/s41598-017-06781-0. Erratum in: Sci Rep. 2018 Jan 8;8(1):517.

8.

Membrane Association Landscape of Myelin Basic Protein Portrays Formation of the Myelin Major Dense Line.

Raasakka A, Ruskamo S, Kowal J, Barker R, Baumann A, Martel A, Tuusa J, Myllykoski M, Bürck J, Ulrich AS, Stahlberg H, Kursula P.

Sci Rep. 2017 Jul 10;7(1):4974. doi: 10.1038/s41598-017-05364-3.

9.

The N-terminal cytoplasmic domain of neuregulin 1 type III is intrinsically disordered.

Chukhlieb M, Raasakka A, Ruskamo S, Kursula P.

Amino Acids. 2015 Aug;47(8):1567-77. doi: 10.1007/s00726-015-1998-x. Epub 2015 May 6.

PMID:
25944317
10.

A role of peripheral myelin protein 2 in lipid homeostasis of myelinating Schwann cells.

Zenker J, Stettner M, Ruskamo S, Domènech-Estévez E, Baloui H, Médard JJ, Verheijen MH, Brouwers JF, Kursula P, Kieseier BC, Chrast R.

Glia. 2014 Sep;62(9):1502-12. doi: 10.1002/glia.22696. Epub 2014 May 21.

PMID:
24849898
11.

A novel structural unit in the N-terminal region of filamins.

Sethi R, Seppälä J, Tossavainen H, Ylilauri M, Ruskamo S, Pentikäinen OT, Pentikäinen U, Permi P, Ylänne J.

J Biol Chem. 2014 Mar 21;289(12):8588-98. doi: 10.1074/jbc.M113.537456. Epub 2014 Jan 27.

12.

Atomic resolution view into the structure-function relationships of the human myelin peripheral membrane protein P2.

Ruskamo S, Yadav RP, Sharma S, Lehtimäki M, Laulumaa S, Aggarwal S, Simons M, Bürck J, Ulrich AS, Juffer AH, Kursula I, Kursula P.

Acta Crystallogr D Biol Crystallogr. 2014 Jan;70(Pt 1):165-76. doi: 10.1107/S1399004713027910. Epub 2013 Dec 31.

13.

Myelin-specific proteins: a structurally diverse group of membrane-interacting molecules.

Han H, Myllykoski M, Ruskamo S, Wang C, Kursula P.

Biofactors. 2013 May-Jun;39(3):233-41. doi: 10.1002/biof.1076. Epub 2013 Jan 24. Review.

PMID:
23780694
14.

Juxtanodin is an intrinsically disordered F-actin-binding protein.

Ruskamo S, Chukhlieb M, Vahokoski J, Bhargav SP, Liang F, Kursula I, Kursula P.

Sci Rep. 2012;2:899. doi: 10.1038/srep00899. Epub 2012 Nov 29.

15.

Production and crystallization of a panel of structure-based mutants of the human myelin peripheral membrane protein P2.

Lehtimäki M, Laulumaa S, Ruskamo S, Kursula P.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Nov 1;68(Pt 11):1359-62. doi: 10.1107/S1744309112039036. Epub 2012 Oct 30.

16.

The C-terminal rod 2 fragment of filamin A forms a compact structure that can be extended.

Ruskamo S, Gilbert R, Hofmann G, Jiang P, Campbell ID, Ylänne J, Pentikäinen U.

Biochem J. 2012 Sep 1;446(2):261-9. doi: 10.1042/BJ20120361.

PMID:
22676060
17.

Assembly of a filamin four-domain fragment and the influence of splicing variant-1 on the structure.

Pentikäinen U, Jiang P, Takala H, Ruskamo S, Campbell ID, Ylänne J.

J Biol Chem. 2011 Jul 29;286(30):26921-30. doi: 10.1074/jbc.M110.195958. Epub 2011 Jun 2.

18.

Structure of the human filamin A actin-binding domain.

Ruskamo S, Ylänne J.

Acta Crystallogr D Biol Crystallogr. 2009 Nov;65(Pt 11):1217-21. doi: 10.1107/S0907444909037330. Epub 2009 Oct 22.

PMID:
19923718
19.

Atomic structures of two novel immunoglobulin-like domain pairs in the actin cross-linking protein filamin.

Heikkinen OK, Ruskamo S, Konarev PV, Svergun DI, Iivanainen T, Heikkinen SM, Permi P, Koskela H, Kilpeläinen I, Ylänne J.

J Biol Chem. 2009 Sep 11;284(37):25450-8. doi: 10.1074/jbc.M109.019661. Epub 2009 Jul 21.

20.

Structural basis of the migfilin-filamin interaction and competition with integrin beta tails.

Lad Y, Jiang P, Ruskamo S, Harburger DS, Ylänne J, Campbell ID, Calderwood DA.

J Biol Chem. 2008 Dec 12;283(50):35154-63. doi: 10.1074/jbc.M802592200. Epub 2008 Sep 30.

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