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Items: 1 to 50 of 82

1.

Betacellulin (BTC) Biases the EGFR To Dimerize with ErbB3.

Rush JS, Peterson JL, Ceresa BP.

Mol Pharmacol. 2018 Dec;94(6):1382-1390. doi: 10.1124/mol.118.113399. Epub 2018 Sep 24.

PMID:
30249613
2.

Nonclinical Safety Assessment of CFZ533, a Fc-Silent Anti-CD40 Antibody, in Cynomolgus Monkeys.

Ulrich P, Flandre T, Espie P, Sickert D, Rubic-Schneider T, Shaw DA, Rush JS.

Toxicol Sci. 2018 Nov 1;166(1):192-202. doi: 10.1093/toxsci/kfy196.

PMID:
30099540
3.

Characterization of the in vitro and in vivo properties of CFZ533, a blocking and non-depleting anti-CD40 monoclonal antibody.

Ristov J, Espie P, Ulrich P, Sickert D, Flandre T, Dimitrova M, Müller-Ristig D, Weider D, Robert G, Schmutz P, Greutmann B, Cordoba-Castro F, Schneider MA, Warncke M, Kolbinger F, Cote S, Heusser C, Bruns C, Rush JS.

Am J Transplant. 2018 Dec;18(12):2895-2904. doi: 10.1111/ajt.14872. Epub 2018 May 24.

PMID:
29665205
4.

Small-molecule inhibitors directly target CARD9 and mimic its protective variant in inflammatory bowel disease.

Leshchiner ES, Rush JS, Durney MA, Cao Z, Dančík V, Chittick B, Wu H, Petrone A, Bittker JA, Phillips A, Perez JR, Shamji AF, Kaushik VK, Daly MJ, Graham DB, Schreiber SL, Xavier RJ.

Proc Natl Acad Sci U S A. 2017 Oct 24;114(43):11392-11397. doi: 10.1073/pnas.1705748114. Epub 2017 Oct 9.

5.

The molecular mechanism of N-acetylglucosamine side-chain attachment to the Lancefield group A carbohydrate in Streptococcus pyogenes.

Rush JS, Edgar RJ, Deng P, Chen J, Zhu H, van Sorge NM, Morris AJ, Korotkov KV, Korotkova N.

J Biol Chem. 2017 Nov 24;292(47):19441-19457. doi: 10.1074/jbc.M117.815910. Epub 2017 Oct 11.

6.

RNF166 Determines Recruitment of Adaptor Proteins during Antibacterial Autophagy.

Heath RJ, Goel G, Baxt LA, Rush JS, Mohanan V, Paulus GLC, Jani V, Lassen KG, Xavier RJ.

Cell Rep. 2016 Nov 22;17(9):2183-2194. doi: 10.1016/j.celrep.2016.11.005.

7.

Administration of Menadione, Vitamin K3, Ameliorates Off-Target Effects on Corneal Epithelial Wound Healing Due to Receptor Tyrosine Kinase Inhibition.

Rush JS, Bingaman DP, Chaney PG, Wax MB, Ceresa BP.

Invest Ophthalmol Vis Sci. 2016 Nov 1;57(14):5864-5871. doi: 10.1167/iovs.16-19952.

PMID:
27802516
8.

SpyB, a Small Heme-Binding Protein, Affects the Composition of the Cell Wall in Streptococcus pyogenes.

Edgar RJ, Chen J, Kant S, Rechkina E, Rush JS, Forsberg LS, Jaehrig B, Azadi P, Tchesnokova V, Sokurenko EV, Zhu H, Korotkov KV, Pancholi V, Korotkova N.

Front Cell Infect Microbiol. 2016 Oct 13;6:126. eCollection 2016.

9.

Genomic and Secondary Metabolite Analyses of Streptomyces sp. 2AW Provide Insight into the Evolution of the Cycloheximide Pathway.

Stulberg ER, Lozano GL, Morin JB, Park H, Baraban EG, Mlot C, Heffelfinger C, Phillips GM, Rush JS, Phillips AJ, Broderick NA, Thomas MG, Stabb EV, Handelsman J.

Front Microbiol. 2016 May 3;7:573. doi: 10.3389/fmicb.2016.00573. eCollection 2016.

10.

ALG1-CDG: Clinical and Molecular Characterization of 39 Unreported Patients.

Ng BG, Shiryaev SA, Rymen D, Eklund EA, Raymond K, Kircher M, Abdenur JE, Alehan F, Midro AT, Bamshad MJ, Barone R, Berry GT, Brumbaugh JE, Buckingham KJ, Clarkson K, Cole FS, O'Connor S, Cooper GM, Van Coster R, Demmer LA, Diogo L, Fay AJ, Ficicioglu C, Fiumara A, Gahl WA, Ganetzky R, Goel H, Harshman LA, He M, Jaeken J, James PM, Katz D, Keldermans L, Kibaek M, Kornberg AJ, Lachlan K, Lam C, Yaplito-Lee J, Nickerson DA, Peters HL, Race V, Régal L, Rush JS, Rutledge SL, Shendure J, Souche E, Sparks SE, Trapane P, Sanchez-Valle A, Vilain E, Vøllo A, Waechter CJ, Wang RY, Wolfe LA, Wong DA, Wood T, Yang AC; University of Washington Center for Mendelian Genomics, Matthijs G, Freeze HH.

Hum Mutat. 2016 Jul;37(7):653-60. doi: 10.1002/humu.22983. Epub 2016 Mar 21.

11.

Role of Flippases in Protein Glycosylation in the Endoplasmic Reticulum.

Rush JS.

Lipid Insights. 2016 Feb 21;8(Suppl 1):45-53. doi: 10.4137/LPI.S31784. eCollection 2015. Review.

12.

Ubiquitin Ligase TRIM62 Regulates CARD9-Mediated Anti-fungal Immunity and Intestinal Inflammation.

Cao Z, Conway KL, Heath RJ, Rush JS, Leshchiner ES, Ramirez-Ortiz ZG, Nedelsky NB, Huang H, Ng A, Gardet A, Cheng SC, Shamji AF, Rioux JD, Wijmenga C, Netea MG, Means TK, Daly MJ, Xavier RJ.

Immunity. 2015 Oct 20;43(4):715-26. doi: 10.1016/j.immuni.2015.10.005.

13.

A novel, blocking, Fc-silent anti-CD40 monoclonal antibody prolongs nonhuman primate renal allograft survival in the absence of B cell depletion.

Cordoba F, Wieczorek G, Audet M, Roth L, Schneider MA, Kunkler A, Stuber N, Erard M, Ceci M, Baumgartner R, Apolloni R, Cattini A, Robert G, Ristig D, Munz J, Haeberli L, Grau R, Sickert D, Heusser C, Espie P, Bruns C, Patel D, Rush JS.

Am J Transplant. 2015 Nov;15(11):2825-36. doi: 10.1111/ajt.13377. Epub 2015 Jul 2.

14.

A new TLR2 agonist promotes cross-presentation by mouse and human antigen presenting cells.

Santone M, Aprea S, Wu TY, Cooke MP, Mbow ML, Valiante NM, Rush JS, Dougan S, Avalos A, Ploegh H, De Gregorio E, Buonsanti C, D'Oro U.

Hum Vaccin Immunother. 2015;11(8):2038-50. doi: 10.1080/21645515.2015.1027467.

15.

Deficiency of MALT1 paracaspase activity results in unbalanced regulatory and effector T and B cell responses leading to multiorgan inflammation.

Bornancin F, Renner F, Touil R, Sic H, Kolb Y, Touil-Allaoui I, Rush JS, Smith PA, Bigaud M, Junker-Walker U, Burkhart C, Dawson J, Niwa S, Katopodis A, Nuesslein-Hildesheim B, Weckbecker G, Zenke G, Kinzel B, Traggiai E, Brenner D, Brüstle A, St Paul M, Zamurovic N, McCoy KD, Rolink A, Régnier CH, Mak TW, Ohashi PS, Patel DD, Calzascia T.

J Immunol. 2015 Apr 15;194(8):3723-34. doi: 10.4049/jimmunol.1402254. Epub 2015 Mar 11.

16.

Novel Citronellyl-Based Photoprobes Designed to Identify ER Proteins Interacting with Dolichyl Phosphate in Yeast and Mammalian Cells.

Rush JS, Subramanian T, Subramanian KL, Onono FO, Waechter CJ, Spielmann HP.

Curr Chem Biol. 2015;9(2):123-141.

17.

Antagonizing c-Cbl enhances EGFR-dependent corneal epithelial homeostasis.

Rush JS, Boeving MA, Berry WL, Ceresa BP.

Invest Ophthalmol Vis Sci. 2014 Jul 1;55(8):4691-9. doi: 10.1167/iovs.14-14133.

18.

Severe, fatal multisystem manifestations in a patient with dolichol kinase-congenital disorder of glycosylation.

Lieu MT, Ng BG, Rush JS, Wood T, Basehore MJ, Hegde M, Chang RC, Abdenur JE, Freeze HH, Wang RY.

Mol Genet Metab. 2013 Dec;110(4):484-9. doi: 10.1016/j.ymgme.2013.09.016. Epub 2013 Oct 4.

19.

RAB7 and TSG101 are required for the constitutive recycling of unliganded EGFRs via distinct mechanisms.

Rush JS, Ceresa BP.

Mol Cell Endocrinol. 2013 Dec 5;381(1-2):188-97. doi: 10.1016/j.mce.2013.07.029. Epub 2013 Aug 7.

20.

Site-specific chemical protein conjugation using genetically encoded aldehyde tags.

Rabuka D, Rush JS, deHart GW, Wu P, Bertozzi CR.

Nat Protoc. 2012 May 10;7(6):1052-67. doi: 10.1038/nprot.2012.045.

21.

Analyses of MbtB, MbtE, and MbtF suggest revisions to the mycobactin biosynthesis pathway in Mycobacterium tuberculosis.

McMahon MD, Rush JS, Thomas MG.

J Bacteriol. 2012 Jun;194(11):2809-18. doi: 10.1128/JB.00088-12. Epub 2012 Mar 23.

22.

Endosomal accumulation of the activated epidermal growth factor receptor (EGFR) induces apoptosis.

Rush JS, Quinalty LM, Engelman L, Sherry DM, Ceresa BP.

J Biol Chem. 2012 Jan 2;287(1):712-22. doi: 10.1074/jbc.M111.294470. Epub 2011 Nov 18.

23.

From commensal to pathogen: translocation of Enterococcus faecalis from the midgut to the hemocoel of Manduca sexta.

Mason KL, Stepien TA, Blum JE, Holt JF, Labbe NH, Rush JS, Raffa KF, Handelsman J.

MBio. 2011 May 17;2(3):e00065-11. doi: 10.1128/mBio.00065-11. Print 2011.

24.

Nogo-B receptor is necessary for cellular dolichol biosynthesis and protein N-glycosylation.

Harrison KD, Park EJ, Gao N, Kuo A, Rush JS, Waechter CJ, Lehrman MA, Sessa WC.

EMBO J. 2011 May 13;30(12):2490-500. doi: 10.1038/emboj.2011.147.

25.

A chemical method for labeling lysine methyltransferase substrates.

Binda O, Boyce M, Rush JS, Palaniappan KK, Bertozzi CR, Gozani O.

Chembiochem. 2011 Jan 24;12(2):330-4. doi: 10.1002/cbic.201000433. Epub 2010 Nov 17.

26.

Bioluminescent probes of sulfatase activity.

Rush JS, Beatty KE, Bertozzi CR.

Chembiochem. 2010 Oct 18;11(15):2096-9. doi: 10.1002/cbic.201000115. No abstract available.

27.

Expression of functional bacterial undecaprenyl pyrophosphate synthase in the yeast rer2{Delta} mutant and CHO cells.

Rush JS, Matveev S, Guan Z, Raetz CR, Waechter CJ.

Glycobiology. 2010 Dec;20(12):1585-93. doi: 10.1093/glycob/cwq107. Epub 2010 Aug 4.

28.

Real-time bioluminescence imaging of glycans on live cells.

Cohen AS, Dubikovskaya EA, Rush JS, Bertozzi CR.

J Am Chem Soc. 2010 Jun 30;132(25):8563-5. doi: 10.1021/ja101766r.

29.

A novel epimerase that converts GlcNAc-P-P-undecaprenol to GalNAc-P-P-undecaprenol in Escherichia coli O157.

Rush JS, Alaimo C, Robbiani R, Wacker M, Waechter CJ.

J Biol Chem. 2010 Jan 15;285(3):1671-80. doi: 10.1074/jbc.M109.061630. Epub 2009 Nov 18.

30.

Suppression of Rft1 expression does not impair the transbilayer movement of Man5GlcNAc2-P-P-dolichol in sealed microsomes from yeast.

Rush JS, Gao N, Lehrman MA, Matveev S, Waechter CJ.

J Biol Chem. 2009 Jul 24;284(30):19835-42. doi: 10.1074/jbc.M109.000893. Epub 2009 Jun 3.

31.

New aldehyde tag sequences identified by screening formylglycine generating enzymes in vitro and in vivo.

Rush JS, Bertozzi CR.

J Am Chem Soc. 2008 Sep 17;130(37):12240-1. doi: 10.1021/ja804530w. Epub 2008 Aug 23.

32.

Does Rft1 flip an N-glycan lipid precursor?

Frank CG, Sanyal S, Rush JS, Waechter CJ, Menon AK.

Nature. 2008 Jul 31;454(7204):E3-4; discussion E4-5. doi: 10.1038/nature07165.

PMID:
18668045
33.
34.

Glycosyltransferase mechanisms: impact of a 5-fluoro substituent in acceptor and donor substrates on catalysis.

Hartman MC, Jiang S, Rush JS, Waechter CJ, Coward JK.

Biochemistry. 2007 Oct 16;46(41):11630-8. Epub 2007 Sep 21.

36.

Expression of activation-induced cytidine deaminase is regulated by cell division, providing a mechanistic basis for division-linked class switch recombination.

Rush JS, Liu M, Odegard VH, Unniraman S, Schatz DG.

Proc Natl Acad Sci U S A. 2005 Sep 13;102(37):13242-7. Epub 2005 Sep 2.

39.
40.

Non-redundancy of cytidine deaminases in class switch recombination.

Fugmann SD, Rush JS, Schatz DG.

Eur J Immunol. 2004 Mar;34(3):844-849. doi: 10.1002/eji.200324418.

41.
42.

Deficiency of UDP-GlcNAc:Dolichol Phosphate N-Acetylglucosamine-1 Phosphate Transferase (DPAGT1) causes a novel congenital disorder of Glycosylation Type Ij.

Wu X, Rush JS, Karaoglu D, Krasnewich D, Lubinsky MS, Waechter CJ, Gilmore R, Freeze HH.

Hum Mutat. 2003 Aug;22(2):144-50.

PMID:
12872255
43.
44.

Identification and characterization of a cDNA encoding a dolichyl pyrophosphate phosphatase located in the endoplasmic reticulum of mammalian cells.

Rush JS, Cho SK, Jiang S, Hofmann SL, Waechter CJ.

J Biol Chem. 2002 Nov 22;277(47):45226-34. Epub 2002 Aug 26.

46.

The CWH8 gene encodes a dolichyl pyrophosphate phosphatase with a luminally oriented active site in the endoplasmic reticulum of Saccharomyces cerevisiae.

Fernandez F, Rush JS, Toke DA, Han GS, Quinn JE, Carman GM, Choi JY, Voelker DR, Aebi M, Waechter CJ.

J Biol Chem. 2001 Nov 2;276(44):41455-64. Epub 2001 Aug 14.

48.
49.

Requirement of the Lec35 gene for all known classes of monosaccharide-P-dolichol-dependent glycosyltransferase reactions in mammals.

Anand M, Rush JS, Ray S, Doucey MA, Weik J, Ware FE, Hofsteenge J, Waechter CJ, Lehrman MA.

Mol Biol Cell. 2001 Feb;12(2):487-501.

50.

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