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Items: 26


Neuropod Cells: Emerging Biology of the Gut-Brain Sensory Transduction.

Kaelberer MM, Rupprecht LE, Liu WW, Weng P, Bohórquez DV.

Annu Rev Neurosci. 2020 Feb 26. doi: 10.1146/annurev-neuro-091619-022657. [Epub ahead of print]


Cholinergic Receptor Blockade in the VTA Attenuates Cue-Induced Cocaine-Seeking and Reverses the Anxiogenic Effects of Forced Abstinence.

Nunes EJ, Bitner L, Hughley SM, Small KM, Walton SN, Rupprecht LE, Addy NA.

Neuroscience. 2019 Aug 10;413:252-263. doi: 10.1016/j.neuroscience.2019.06.028. Epub 2019 Jul 2.


Nicotine Self-administration Is Not Increased in the Methylazoxymethanol Acetate Rodent Model of Schizophrenia.

Weeks JJ, Rupprecht LE, Grace AA, Donny EC, Sved AF.

Nicotine Tob Res. 2020 Feb 6;22(2):204-212. doi: 10.1093/ntr/ntz048.


Neurobiological and Neurophysiological Mechanisms Underlying Nicotine Seeking and Smoking Relapse.

Schmidt HD, Rupprecht LE, Addy NA.

Mol Neuropsychiatry. 2019 Feb;4(4):169-189. doi: 10.1159/000494799. Epub 2018 Nov 19. Review.


Self-administered nicotine increases fat metabolism and suppresses weight gain in male rats.

Rupprecht LE, Kreisler AD, Spierling SR, de Guglielmo G, Kallupi M, George O, Donny EC, Zorrilla EP, Sved AF.

Psychopharmacology (Berl). 2018 Apr;235(4):1131-1140. doi: 10.1007/s00213-018-4830-y. Epub 2018 Jan 21.


Basic Science and Public Policy: Informed Regulation for Nicotine and Tobacco Products.

Fowler CD, Gipson CD, Kleykamp BA, Rupprecht LE, Harrell PT, Rees VW, Gould TJ, Oliver J, Bagdas D, Damaj MI, Schmidt HD, Duncan A, De Biasi M; Basic Science Network (BSN) of the Society for Research on Nicotine and Tobacco (SRNT).

Nicotine Tob Res. 2018 Jun 7;20(7):789-799. doi: 10.1093/ntr/ntx175. Review.


Animal Research on Nicotine Reduction: Current Evidence and Research Gaps.

Smith TT, Rupprecht LE, Denlinger-Apte RL, Weeks JJ, Panas RS, Donny EC, Sved AF.

Nicotine Tob Res. 2017 Sep 1;19(9):1005-1015. doi: 10.1093/ntr/ntx077.


Repeated administration of an acetylcholinesterase inhibitor attenuates nicotine taking in rats and smoking behavior in human smokers.

Ashare RL, Kimmey BA, Rupprecht LE, Bowers ME, Hayes MR, Schmidt HD.

Transl Psychiatry. 2017 Mar 28;7(3):e1072. doi: 10.1038/tp.2017.46. No abstract available.


Self-administered nicotine differentially impacts body weight gain in obesity-prone and obesity-resistant rats.

Rupprecht LE, Smith TT, Donny EC, Sved AF.

Physiol Behav. 2017 Jul 1;176:71-75. doi: 10.1016/j.physbeh.2017.02.007. Epub 2017 Feb 9.


Reducing nicotine exposure results in weight gain in smokers randomised to very low nicotine content cigarettes.

Rupprecht LE, Koopmeiners JS, Dermody SS, Oliver JA, al'Absi M, Benowitz NL, Denlinger-Apte R, Drobes DJ, Hatsukami D, McClernon FJ, Pacek LR, Smith TT, Sved AF, Tidey J, Vandrey R, Donny EC.

Tob Control. 2017 Mar;26(e1):e43-e48. doi: 10.1136/tobaccocontrol-2016-053301. Epub 2016 Nov 17.


Characterizing the relationship between increases in the cost of nicotine and decreases in nicotine content in adult male rats: implications for tobacco regulation.

Smith TT, Rupprecht LE, Sved AF, Donny EC.

Psychopharmacology (Berl). 2016 Dec;233(23-24):3953-3964. Epub 2016 Sep 14.


Self-Administered Nicotine Suppresses Body Weight Gain Independent of Food Intake in Male Rats.

Rupprecht LE, Smith TT, Donny EC, Sved AF.

Nicotine Tob Res. 2016 Sep;18(9):1869-1876. doi: 10.1093/ntr/ntw113. Epub 2016 May 18.


Effects of Monoamine Oxidase Inhibition on the Reinforcing Properties of Low-Dose Nicotine.

Smith TT, Rupprecht LE, Cwalina SN, Onimus MJ, Murphy SE, Donny EC, Sved AF.

Neuropsychopharmacology. 2016 Aug;41(9):2335-43. doi: 10.1038/npp.2016.36. Epub 2016 Mar 9.


Repeated administration of an acetylcholinesterase inhibitor attenuates nicotine taking in rats and smoking behavior in human smokers.

Ashare RL, Kimmey BA, Rupprecht LE, Bowers ME, Hayes MR, Schmidt HD.

Transl Psychiatry. 2016 Jan 19;6:e713. doi: 10.1038/tp.2015.209. Erratum in: Transl Psychiatry. 2017 Mar 28;7(3):e1072.


Adolescent Rats Self-Administer Less Nicotine Than Adults at Low Doses.

Schassburger RL, Pitzer EM, Smith TT, Rupprecht LE, Thiels E, Donny EC, Sved AF.

Nicotine Tob Res. 2016 Sep;18(9):1861-1868. doi: 10.1093/ntr/ntw006. Epub 2016 Jan 13.


Hindbrain GLP-1 receptor mediation of cisplatin-induced anorexia and nausea.

De Jonghe BC, Holland RA, Olivos DR, Rupprecht LE, Kanoski SE, Hayes MR.

Physiol Behav. 2016 Jan 1;153:109-14. doi: 10.1016/j.physbeh.2015.10.031. Epub 2015 Nov 7.


Obese Smokers as a Potential Subpopulation of Risk in Tobacco Reduction Policy.

Rupprecht LE, Donny EC, Sved AF.

Yale J Biol Med. 2015 Sep 3;88(3):289-94. eCollection 2015 Sep. Review.


Effects of MAO inhibition and a combination of minor alkaloids, β-carbolines, and acetaldehyde on nicotine self-administration in adult male rats.

Smith TT, Schaff MB, Rupprecht LE, Schassburger RL, Buffalari DM, Murphy SE, Sved AF, Donny EC.

Drug Alcohol Depend. 2015 Oct 1;155:243-52. doi: 10.1016/j.drugalcdep.2015.07.002. Epub 2015 Jul 13.


Behavioral mechanisms underlying nicotine reinforcement.

Rupprecht LE, Smith TT, Schassburger RL, Buffalari DM, Sved AF, Donny EC.

Curr Top Behav Neurosci. 2015;24:19-53. doi: 10.1007/978-3-319-13482-6_2. Review.


The food intake-suppressive effects of glucagon-like peptide-1 receptor signaling in the ventral tegmental area are mediated by AMPA/kainate receptors.

Mietlicki-Baase EG, Ortinski PI, Rupprecht LE, Olivos DR, Alhadeff AL, Pierce RC, Hayes MR.

Am J Physiol Endocrinol Metab. 2013 Dec 1;305(11):E1367-74. doi: 10.1152/ajpendo.00413.2013. Epub 2013 Oct 8.


Hindbrain GLP-1 receptor-mediated suppression of food intake requires a PI3K-dependent decrease in phosphorylation of membrane-bound Akt.

Rupprecht LE, Mietlicki-Baase EG, Zimmer DJ, McGrath LE, Olivos DR, Hayes MR.

Am J Physiol Endocrinol Metab. 2013 Sep 15;305(6):E751-9. doi: 10.1152/ajpendo.00367.2013. Epub 2013 Jul 30.


Amylin receptor signaling in the ventral tegmental area is physiologically relevant for the control of food intake.

Mietlicki-Baase EG, Rupprecht LE, Olivos DR, Zimmer DJ, Alter MD, Pierce RC, Schmidt HD, Hayes MR.

Neuropsychopharmacology. 2013 Aug;38(9):1685-97. doi: 10.1038/npp.2013.66. Epub 2013 Mar 8.


Donepezil, an acetylcholinesterase inhibitor, attenuates nicotine self-administration and reinstatement of nicotine seeking in rats.

Kimmey BA, Rupprecht LE, Hayes MR, Schmidt HD.

Addict Biol. 2014 Jul;19(4):539-51. doi: 10.1111/adb.12014. Epub 2012 Dec 12.


Galantamine, an acetylcholinesterase inhibitor and positive allosteric modulator of nicotinic acetylcholine receptors, attenuates nicotine taking and seeking in rats.

Hopkins TJ, Rupprecht LE, Hayes MR, Blendy JA, Schmidt HD.

Neuropsychopharmacology. 2012 Sep;37(10):2310-21. doi: 10.1038/npp.2012.83. Epub 2012 Jun 6.


The role of nausea in food intake and body weight suppression by peripheral GLP-1 receptor agonists, exendin-4 and liraglutide.

Kanoski SE, Rupprecht LE, Fortin SM, De Jonghe BC, Hayes MR.

Neuropharmacology. 2012 Apr;62(5-6):1916-27. doi: 10.1016/j.neuropharm.2011.12.022. Epub 2011 Dec 28.


GLP-1 neurons in the nucleus of the solitary tract project directly to the ventral tegmental area and nucleus accumbens to control for food intake.

Alhadeff AL, Rupprecht LE, Hayes MR.

Endocrinology. 2012 Feb;153(2):647-58. doi: 10.1210/en.2011-1443. Epub 2011 Nov 29.

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