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Insights into the assembly and activation of the microtubule nucleator γ-TuRC.

Liu P, Zupa E, Neuner A, Böhler A, Loerke J, Flemming D, Ruppert T, Rudack T, Peter C, Spahn C, Gruss OJ, Pfeffer S, Schiebel E.

Nature. 2020 Feb;578(7795):467-471. doi: 10.1038/s41586-019-1896-6. Epub 2019 Dec 19.


Joint recommendations for a total services account as a factor in simplifying contracts.

Bruns I, Schade-Brittinger C, Wissing F, Ruppert T, Trillsch M.

Ger Med Sci. 2019 Oct 24;17:Doc10. doi: 10.3205/000276. eCollection 2019. Review.


YAP-dependent induction of UHMK1 supports nuclear enrichment of the oncogene MYBL2 and proliferation in liver cancer cells.

Wei T, Weiler SME, Tóth M, Sticht C, Lutz T, Thomann S, De La Torre C, Straub B, Merker S, Ruppert T, Marquardt J, Singer S, Gretz N, Schirmacher P, Breuhahn K.

Oncogene. 2019 Jul;38(27):5541-5550. doi: 10.1038/s41388-019-0801-y. Epub 2019 Apr 1.


SIRT7-Dependent Deacetylation of Fibrillarin Controls Histone H2A Methylation and rRNA Synthesis during the Cell Cycle.

Iyer-Bierhoff A, Krogh N, Tessarz P, Ruppert T, Nielsen H, Grummt I.

Cell Rep. 2018 Dec 11;25(11):2946-2954.e5. doi: 10.1016/j.celrep.2018.11.051.


The human phosphatase CDC14A modulates primary cilium length by regulating centrosomal actin nucleation.

Uddin B, Partscht P, Chen NP, Neuner A, Weiß M, Hardt R, Jafarpour A, Heßling B, Ruppert T, Lorenz H, Pereira G, Schiebel E.

EMBO Rep. 2019 Jan;20(1). pii: e46544. doi: 10.15252/embr.201846544. Epub 2018 Nov 22.


Software Sensor for Activity-Time Monitoring and Fault Detection in Production Lines.

Ruppert T, Abonyi J.

Sensors (Basel). 2018 Jul 19;18(7). pii: E2346. doi: 10.3390/s18072346.


A role for 2-Cys peroxiredoxins in facilitating cytosolic protein thiol oxidation.

Stöcker S, Maurer M, Ruppert T, Dick TP.

Nat Chem Biol. 2018 Feb;14(2):148-155. doi: 10.1038/nchembio.2536. Epub 2017 Dec 18.


Effects of a video feedback parent training program during child welfare visitation.

Nese RNT, Anderson CM, Ruppert T, Fisher PA.

Child Youth Serv Rev. 2016 Dec;71:266-276. doi: 10.1016/j.childyouth.2016.11.007. Epub 2016 Nov 8.


Human phosphatase CDC14A regulates actin organization through dephosphorylation of epithelial protein lost in neoplasm.

Chen NP, Uddin B, Hardt R, Ding W, Panic M, Lucibello I, Kammerer P, Ruppert T, Schiebel E.

Proc Natl Acad Sci U S A. 2017 May 16;114(20):5201-5206. doi: 10.1073/pnas.1619356114. Epub 2017 May 2.


Stress-Induced Protein S-Glutathionylation and S-Trypanothionylation in African Trypanosomes-A Quantitative Redox Proteome and Thiol Analysis.

Ulrich K, Finkenzeller C, Merker S, Rojas F, Matthews K, Ruppert T, Krauth-Siegel RL.

Antioxid Redox Signal. 2017 Sep 20;27(9):517-533. doi: 10.1089/ars.2016.6947. Epub 2017 Mar 24.


Current practice and perspectives in CRO oversight based on a survey performed among members of the German Association of Research-Based Pharmaceutical Companies (vfa).

Hennig M, Hundt F, Busta S, Mikus S, Sanden PH, Sörgel A, Ruppert T.

Ger Med Sci. 2017 Jan 26;15:Doc02. doi: 10.3205/000243. eCollection 2017.


Expression of the novel maternal centrosome assembly factor Wdr8 is required for vertebrate embryonic mitoses.

Inoue D, Stemmer M, Thumberger T, Ruppert T, Bärenz F, Wittbrodt J, Gruss OJ.

Nat Commun. 2017 Jan 18;8:14090. doi: 10.1038/ncomms14090.


Protein O-Mannosylation in the Murine Brain: Occurrence of Mono-O-Mannosyl Glycans and Identification of New Substrates.

Bartels MF, Winterhalter PR, Yu J, Liu Y, Lommel M, Möhrlen F, Hu H, Feizi T, Westerlind U, Ruppert T, Strahl S.

PLoS One. 2016 Nov 3;11(11):e0166119. doi: 10.1371/journal.pone.0166119. eCollection 2016.


The HMGB1 protein induces a metabolic type of tumour cell death by blocking aerobic respiration.

Gdynia G, Sauer SW, Kopitz J, Fuchs D, Duglova K, Ruppert T, Miller M, Pahl J, Cerwenka A, Enders M, Mairbäurl H, Kamiński MM, Penzel R, Zhang C, Fuller JC, Wade RC, Benner A, Chang-Claude J, Brenner H, Hoffmeister M, Zentgraf H, Schirmacher P, Roth W.

Nat Commun. 2016 Mar 7;7:10764. doi: 10.1038/ncomms10764.


Transition Supports for At-Risk Students: A Case Example.

Buchanan R, Ruppert T, Cariveau T.

J Risk Issues. 2016;19(2):9-15.


WDR8 is a centriolar satellite and centriole-associated protein that promotes ciliary vesicle docking during ciliogenesis.

Kurtulmus B, Wang W, Ruppert T, Neuner A, Cerikan B, Viol L, Dueñas-Sánchez R, Gruss OJ, Pereira G.

J Cell Sci. 2016 Feb 1;129(3):621-36. doi: 10.1242/jcs.179713. Epub 2015 Dec 16.


Refining an intervention for students with emotional disturbance using qualitative parent and teacher data.

Buchanan R, Nese RNT, Palinkas LA, Ruppert T.

Child Youth Serv Rev. 2015 Nov;58:41-49. doi: 10.1016/j.childyouth.2015.08.014. Epub 2015 Aug 24.


Molecular and biochemical alterations in tubular epithelial cells of patients with isolated methylmalonic aciduria.

Ruppert T, Schumann A, Gröne HJ, Okun JG, Kölker S, Morath MA, Sauer SW.

Hum Mol Genet. 2015 Dec 15;24(24):7049-59. doi: 10.1093/hmg/ddv405. Epub 2015 Sep 29.


Preventing E-cadherin aberrant N-glycosylation at Asn-554 improves its critical function in gastric cancer.

Carvalho S, Catarino TA, Dias AM, Kato M, Almeida A, Hessling B, Figueiredo J, Gärtner F, Sanches JM, Ruppert T, Miyoshi E, Pierce M, Carneiro F, Kolarich D, Seruca R, Yamaguchi Y, Taniguchi N, Reis CA, Pinho SS.

Oncogene. 2016 Mar 31;35(13):1619-31. doi: 10.1038/onc.2015.225. Epub 2015 Jul 20.


Maleic Acid--but Not Structurally Related Methylmalonic Acid--Interrupts Energy Metabolism by Impaired Calcium Homeostasis.

Tuncel AT, Ruppert T, Wang BT, Okun JG, Kölker S, Morath MA, Sauer SW.

PLoS One. 2015 Jun 18;10(6):e0128770. doi: 10.1371/journal.pone.0128770. eCollection 2015.


Peroxiredoxin-2 and STAT3 form a redox relay for H2O2 signaling.

Sobotta MC, Liou W, Stöcker S, Talwar D, Oehler M, Ruppert T, Scharf AN, Dick TP.

Nat Chem Biol. 2015 Jan;11(1):64-70. doi: 10.1038/nchembio.1695. Epub 2014 Nov 24.


Pediatric psychopharmacological research in the post EU regulation 1901/2006 era.

Schmäl C, Becker K, Berg R, Brünger M, Lehmkuhl G, Oehler KU, Ruppert T, Staudter C, Trott GE, Dittmann RW.

Z Kinder Jugendpsychiatr Psychother. 2014 Nov;42(6):441-9. doi: 10.1024/1422-4917/a000322.


Patient relevant endpoints in oncology: current issues in the context of early benefit assessment in Germany.

Dabisch I, Dethling J, Dintsios CM, Drechsler M, Kalanovic D, Kaskel P, Langer F, Ruof J, Ruppert T, Wirth D.

Health Econ Rev. 2014 Jan 24;4(1):2. doi: 10.1186/2191-1991-4-2.


Proteins and lipids of glycosomal membranes from Leishmania tarentolae and Trypanosoma brucei.

Colasante C, Voncken F, Manful T, Ruppert T, Tielens AGM, van Hellemond JJ, Clayton C.

F1000Res. 2013 Jan 29;2:27. doi: 10.12688/f1000research.2-27.v1. eCollection 2013.


TNF-α mediates mitochondrial uncoupling and enhances ROS-dependent cell migration via NF-κB activation in liver cells.

Kastl L, Sauer SW, Ruppert T, Beissbarth T, Becker MS, Süss D, Krammer PH, Gülow K.

FEBS Lett. 2014 Jan 3;588(1):175-83. doi: 10.1016/j.febslet.2013.11.033. Epub 2013 Dec 4.


Protein O-mannosylation is crucial for E-cadherin-mediated cell adhesion.

Lommel M, Winterhalter PR, Willer T, Dahlhoff M, Schneider MR, Bartels MF, Renner-Müller I, Ruppert T, Wolf E, Strahl S.

Proc Natl Acad Sci U S A. 2013 Dec 24;110(52):21024-9. doi: 10.1073/pnas.1316753110. Epub 2013 Dec 2.


O-glycosylation of the non-canonical T-cadherin from rabbit skeletal muscle by single mannose residues.

Winterhalter PR, Lommel M, Ruppert T, Strahl S.

FEBS Lett. 2013 Nov 15;587(22):3715-21. doi: 10.1016/j.febslet.2013.09.041. Epub 2013 Oct 7.


The centriolar satellite protein SSX2IP promotes centrosome maturation.

Bärenz F, Inoue D, Yokoyama H, Tegha-Dunghu J, Freiss S, Draeger S, Mayilo D, Cado I, Merker S, Klinger M, Hoeckendorf B, Pilz S, Hupfeld K, Steinbeisser H, Lorenz H, Ruppert T, Wittbrodt J, Gruss OJ.

J Cell Biol. 2013 Jul 8;202(1):81-95. doi: 10.1083/jcb.201302122. Epub 2013 Jul 1.


The in vivo TRPV6 protein starts at a non-AUG triplet, decoded as methionine, upstream of canonical initiation at AUG.

Fecher-Trost C, Wissenbach U, Beck A, Schalkowsky P, Stoerger C, Doerr J, Dembek A, Simon-Thomas M, Weber A, Wollenberg P, Ruppert T, Middendorff R, Maurer HH, Flockerzi V.

J Biol Chem. 2013 Jun 7;288(23):16629-44. doi: 10.1074/jbc.M113.469726. Epub 2013 Apr 23.


Detection and initial characterization of protein entities consisting of the HIV glycoprotein cytoplasmic C-terminal domain alone.

Pfeiffer T, Ruppert T, Schaal H, Bosch V.

Virology. 2013 Jun 20;441(1):85-94. doi: 10.1016/j.virol.2013.03.009. Epub 2013 Apr 3.


T cell activation is driven by an ADP-dependent glucokinase linking enhanced glycolysis with mitochondrial reactive oxygen species generation.

Kamiński MM, Sauer SW, Kamiński M, Opp S, Ruppert T, Grigaravičius P, Grudnik P, Gröne HJ, Krammer PH, Gülow K.

Cell Rep. 2012 Nov 29;2(5):1300-15. doi: 10.1016/j.celrep.2012.10.009. Epub 2012 Nov 15.


Toward visualization in policy modeling.

Kohlhammer J, Nazemi K, Ruppert T, Burkhardt D.

IEEE Comput Graph Appl. 2012 Sep-Oct;32(5):84-9. doi: 10.1109/MCG.2012.107.


The balance in the delivery of ER components and the vacuolar proton pump to the phagosome depends on myosin IK in Dictyostelium.

Dieckmann R, Guého A, Monroy R, Ruppert T, Bloomfield G, Soldati T.

Mol Cell Proteomics. 2012 Oct;11(10):886-900. Epub 2012 Jun 26.


Remuneration for non-interventional studies--results of a survey in the pharmaceutical industry in Germany.

Ruppert T, Hahn M, Hundt F.

Ger Med Sci. 2012;10:Doc04. doi: 10.3205/000155. Epub 2012 Feb 7.


S100A9 is a biliary protein marker of disease activity in primary sclerosing cholangitis.

Reinhard L, Rupp C, Riedel HD, Ruppert T, Giese T, Flechtenmacher C, Weiss KH, Kloeters-Plachky P, Stremmel W, Schirmacher P, Sauer P, Gotthardt DN.

PLoS One. 2012;7(1):e29821. doi: 10.1371/journal.pone.0029821. Epub 2012 Jan 11.


Enzymes of cysteine synthesis show extensive and conserved modifications patterns that include N(α)-terminal acetylation.

Wirtz M, Heeg C, Samami AA, Ruppert T, Hell R.

Amino Acids. 2010 Oct;39(4):1077-86. doi: 10.1007/s00726-010-0694-0. Epub 2010 Jul 24.


The role of protein quality control in mitochondrial protein homeostasis under oxidative stress.

Bender T, Leidhold C, Ruppert T, Franken S, Voos W.

Proteomics. 2010 Apr;10(7):1426-43. doi: 10.1002/pmic.200800619.


Alkylation of adenosine deaminase and thioredoxin by acrylamide in human cell cultures.

Schwend T, Möller M, Schabacker J, Ruppert T, Wink M.

Z Naturforsch C J Biosci. 2009 May-Jun;64(5-6):447-53.


Mimicking Ndc80 phosphorylation triggers spindle assembly checkpoint signalling.

Kemmler S, Stach M, Knapp M, Ortiz J, Pfannstiel J, Ruppert T, Lechner J.

EMBO J. 2009 Apr 22;28(8):1099-110. doi: 10.1038/emboj.2009.62. Epub 2009 Mar 19.


The gene mpn310 (hmw2) from Mycoplasma pneumoniae encodes two proteins, HMW2 and HMW2-s, which differ in size but use the same reading frame.

Boonmee A, Ruppert T, Herrmann R.

FEMS Microbiol Lett. 2009 Jan;290(2):174-81. doi: 10.1111/j.1574-6968.2008.01422.x. Epub 2008 Nov 19.


EML3 is a nuclear microtubule-binding protein required for the correct alignment of chromosomes in metaphase.

Tegha-Dunghu J, Neumann B, Reber S, Krause R, Erfle H, Walter T, Held M, Rogers P, Hupfeld K, Ruppert T, Ellenberg J, Gruss OJ.

J Cell Sci. 2008 May 15;121(Pt 10):1718-26. doi: 10.1242/jcs.019174. Epub 2008 Apr 29.


Analysis of the Arabidopsis O-acetylserine(thiol)lyase gene family demonstrates compartment-specific differences in the regulation of cysteine synthesis.

Heeg C, Kruse C, Jost R, Gutensohn M, Ruppert T, Wirtz M, Hell R.

Plant Cell. 2008 Jan;20(1):168-85. doi: 10.1105/tpc.107.056747. Epub 2008 Jan 25.


Gliotoxin production by clinical and environmental Aspergillus fumigatus strains.

Kupfahl C, Michalka A, Lass-Flörl C, Fischer G, Haase G, Ruppert T, Geginat G, Hof H.

Int J Med Microbiol. 2008 Apr;298(3-4):319-27. Epub 2007 Jun 15.


Candida species fail to produce the immunosuppressive secondary metabolite gliotoxin in vitro.

Kupfahl C, Ruppert T, Dietz A, Geginat G, Hof H.

FEMS Yeast Res. 2007 Sep;7(6):986-92. Epub 2007 May 31.


Catalytic mechanism of the glutathione peroxidase-type tryparedoxin peroxidase of Trypanosoma brucei.

Schlecker T, Comini MA, Melchers J, Ruppert T, Krauth-Siegel RL.

Biochem J. 2007 Aug 1;405(3):445-54.


The Drosophila mitotic inhibitor Frühstart specifically binds to the hydrophobic patch of cyclins.

Gawliński P, Nikolay R, Goursot C, Lawo S, Chaurasia B, Herz HM, Kussler-Schneider Y, Ruppert T, Mayer M, Grosshans J.

EMBO Rep. 2007 May;8(5):490-6. Epub 2007 Apr 13.


Glutathionylation of trypanosomal thiol redox proteins.

Melchers J, Dirdjaja N, Ruppert T, Krauth-Siegel RL.

J Biol Chem. 2007 Mar 23;282(12):8678-94. Epub 2007 Jan 22.

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