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Items: 24

1.

The Novel Bromodomain and Extraterminal Domain Inhibitor INCB054329 Induces Vulnerabilities in Myeloma Cells That Inform Rational Combination Strategies.

Stubbs MC, Burn TC, Sparks RB, Maduskuie T, Diamond S, Rupar M, Wen X, Volgina A, Zolotarjova N, Waeltz P, Favata M, Jalluri R, Liu H, Liu XM, Li J, Collins R, Falahatpisheh N, Polam P, DiMatteo D, Feldman P, Dostalik V, Thekkat P, Gardiner C, He X, Li Y, Covington M, Wynn R, Ruggeri B, Yeleswaram S, Xue C, Yao W, Combs AP, Huber R, Hollis G, Scherle P, Liu P.

Clin Cancer Res. 2018 Sep 11. pii: clincanres.0098.2018. doi: 10.1158/1078-0432.CCR-18-0098. [Epub ahead of print]

PMID:
30206163
2.

Monolith Chromatography as Sample Preparation Step in Virome Studies of Water Samples.

Gutiérrez-Aguirre I, Kutnjak D, Rački N, Rupar M, Ravnikar M.

Methods Mol Biol. 2018;1746:63-75. doi: 10.1007/978-1-4939-7683-6_6.

PMID:
29492887
3.

INCB040093 Is a Novel PI3Kδ Inhibitor for the Treatment of B Cell Lymphoid Malignancies.

Shin N, Li YL, Mei S, Wang KH, Hall L, Katiyar K, Wang Q, Yang G, Rumberger B, Leffet L, He X, Rupar M, Bowman K, Favata M, Li J, Liu M, Li Y, Covington M, Koblish H, Soloviev M, Shuey D, Burn T, Diamond S, Fridman J, Combs A, Yao W, Yeleswaram S, Hollis G, Vaddi K, Huber R, Newton R, Scherle P.

J Pharmacol Exp Ther. 2018 Jan;364(1):120-130. doi: 10.1124/jpet.117.244947. Epub 2017 Nov 10.

PMID:
29127109
4.

Deep sequencing of virus-derived small interfering RNAs and RNA from viral particles shows highly similar mutational landscapes of a plant virus population.

Kutnjak D, Rupar M, Gutierrez-Aguirre I, Curk T, Kreuze JF, Ravnikar M.

J Virol. 2015 May;89(9):4760-9. doi: 10.1128/JVI.03685-14. Epub 2015 Feb 11.

5.

The Janus kinase 2 inhibitor fedratinib inhibits thiamine uptake: a putative mechanism for the onset of Wernicke's encephalopathy.

Zhang Q, Zhang Y, Diamond S, Boer J, Harris JJ, Li Y, Rupar M, Behshad E, Gardiner C, Collier P, Liu P, Burn T, Wynn R, Hollis G, Yeleswaram S.

Drug Metab Dispos. 2014 Oct;42(10):1656-62. doi: 10.1124/dmd.114.058883. Epub 2014 Jul 25.

6.

Surface plasmon resonance for monitoring the interaction of Potato virus Y with monoclonal antibodies.

Gutiérrez-Aguirre I, Hodnik V, Glais L, Rupar M, Jacquot E, Anderluh G, Ravnikar M.

Anal Biochem. 2014 Feb 15;447:74-81. doi: 10.1016/j.ab.2013.10.032. Epub 2013 Nov 9.

PMID:
24220292
7.

Validation of standards for quantitative assessment of JAK2 c.1849G>T (p.V617F) allele burden analysis in clinical samples.

Collier P, Patel K, Waeltz P, Rupar M, Luthra R, Liu PC, Hollis G, Huber R, Verstovsek S, Burn TC.

Genet Test Mol Biomarkers. 2013 May;17(5):429-37. doi: 10.1089/gtmb.2012.0366. Epub 2013 Mar 28.

8.

Assessment of SNaPshot and single step RT-qPCR methods for discriminating Potato virus Y (PVY) subgroups.

Rupar M, Kogovšek P, Pompe-Novak M, Gutiérrez-Aguirre I, Delaunay A, Jacquot E, Ravnikar M.

J Virol Methods. 2013 Apr;189(1):93-100. doi: 10.1016/j.jviromet.2013.01.013. Epub 2013 Feb 5.

PMID:
23396125
9.

Fast purification of the filamentous Potato virus Y using monolithic chromatographic supports.

Rupar M, Ravnikar M, Tušek-Žnidarič M, Kramberger P, Glais L, Gutiérrez-Aguirre I.

J Chromatogr A. 2013 Jan 11;1272:33-40. doi: 10.1016/j.chroma.2012.11.058. Epub 2012 Nov 29.

PMID:
23253119
10.

Automated DNA extraction for large numbers of plant samples.

Mehle N, Nikolić P, Rupar M, Boben J, Ravnikar M, Dermastia M.

Methods Mol Biol. 2013;938:139-45. doi: 10.1007/978-1-62703-089-2_12.

PMID:
22987412
11.

Molecular evolution and phylogeography of potato virus Y based on the CP gene.

Cuevas JM, Delaunay A, Rupar M, Jacquot E, Elena SF.

J Gen Virol. 2012 Nov;93(Pt 11):2496-501. doi: 10.1099/vir.0.044347-0. Epub 2012 Jul 25.

PMID:
22837421
12.

Phosphorylation State-Dependent High Throughput Screening of the c-Met Kinase.

Behshad E, Klabe RM, Margulis A, Becker-Pasha M, Rupar MJ, Collier P, Liu PC, Hollis GF, Burn TC, Wynn R.

Curr Chem Genomics. 2010 Apr 23;4:27-33. doi: 10.2174/1875397301004010027.

13.

Selective inhibition of IDO1 effectively regulates mediators of antitumor immunity.

Liu X, Shin N, Koblish HK, Yang G, Wang Q, Wang K, Leffet L, Hansbury MJ, Thomas B, Rupar M, Waeltz P, Bowman KJ, Polam P, Sparks RB, Yue EW, Li Y, Wynn R, Fridman JS, Burn TC, Combs AP, Newton RC, Scherle PA.

Blood. 2010 Apr 29;115(17):3520-30. doi: 10.1182/blood-2009-09-246124. Epub 2010 Mar 2.

14.

Efficacy of the JAK2 inhibitor INCB16562 in a murine model of MPLW515L-induced thrombocytosis and myelofibrosis.

Koppikar P, Abdel-Wahab O, Hedvat C, Marubayashi S, Patel J, Goel A, Kucine N, Gardner JR, Combs AP, Vaddi K, Haley PJ, Burn TC, Rupar M, Bromberg JF, Heaney ML, de Stanchina E, Fridman JS, Levine RL.

Blood. 2010 Apr 8;115(14):2919-27. doi: 10.1182/blood-2009-04-218842. Epub 2010 Feb 12.

15.

Preclinical characterization of the selective JAK1/2 inhibitor INCB018424: therapeutic implications for the treatment of myeloproliferative neoplasms.

Quintás-Cardama A, Vaddi K, Liu P, Manshouri T, Li J, Scherle PA, Caulder E, Wen X, Li Y, Waeltz P, Rupar M, Burn T, Lo Y, Kelley J, Covington M, Shepard S, Rodgers JD, Haley P, Kantarjian H, Fridman JS, Verstovsek S.

Blood. 2010 Apr 15;115(15):3109-17. doi: 10.1182/blood-2009-04-214957. Epub 2010 Feb 3.

16.

High-throughput determination of mode of inhibition in lead identification and optimization.

Wei M, Wynn R, Hollis G, Liao B, Margulis A, Reid BG, Klabe R, Liu PC, Becker-Pasha M, Rupar M, Burn TC, McCall DE, Li Y.

J Biomol Screen. 2007 Mar;12(2):220-8.

PMID:
17351185
17.

Potent benzimidazole sulfonamide protein tyrosine phosphatase 1B inhibitors containing the heterocyclic (S)-isothiazolidinone phosphotyrosine mimetic.

Combs AP, Zhu W, Crawley ML, Glass B, Polam P, Sparks RB, Modi D, Takvorian A, McLaughlin E, Yue EW, Wasserman Z, Bower M, Wei M, Rupar M, Ala PJ, Reid BM, Ellis D, Gonneville L, Emm T, Taylor N, Yeleswaram S, Li Y, Wynn R, Burn TC, Hollis G, Liu PC, Metcalf B.

J Med Chem. 2006 Jun 29;49(13):3774-89.

PMID:
16789735
18.

Identification of ADAM10 as a major source of HER2 ectodomain sheddase activity in HER2 overexpressing breast cancer cells.

Liu PC, Liu X, Li Y, Covington M, Wynn R, Huber R, Hillman M, Yang G, Ellis D, Marando C, Katiyar K, Bradley J, Abremski K, Stow M, Rupar M, Zhuo J, Li YL, Lin Q, Burns D, Xu M, Zhang C, Qian DQ, He C, Sharief V, Weng L, Agrios C, Shi E, Metcalf B, Newton R, Friedman S, Yao W, Scherle P, Hollis G, Burn TC.

Cancer Biol Ther. 2006 Jun;5(6):657-64. Epub 2006 Jun 14.

PMID:
16627989
19.

Binary toxins from Bacillus thuringiensis active against the western corn rootworm, Diabrotica virgifera virgifera LeConte.

Baum JA, Chu CR, Rupar M, Brown GR, Donovan WP, Huesing JE, Ilagan O, Malvar TM, Pleau M, Walters M, Vaughn T.

Appl Environ Microbiol. 2004 Aug;70(8):4889-98.

20.

Purification of Her-2 extracellular domain and identification of its cleavage site.

Yuan CX, Lasut AL, Wynn R, Neff NT, Hollis GF, Ramaker ML, Rupar MJ, Liu P, Meade R.

Protein Expr Purif. 2003 Jun;29(2):217-22.

PMID:
12767812
21.

Generation of multiple farnesoid-X-receptor isoforms through the use of alternative promoters.

Huber RM, Murphy K, Miao B, Link JR, Cunningham MR, Rupar MJ, Gunyuzlu PL, Haws TF, Kassam A, Powell F, Hollis GF, Young PR, Mukherjee R, Burn TC.

Gene. 2002 May 15;290(1-2):35-43.

PMID:
12062799
22.

Absence of post-translational aspartyl beta-hydroxylation of epidermal growth factor domains in mice leads to developmental defects and an increased incidence of intestinal neoplasia.

Dinchuk JE, Focht RJ, Kelley JA, Henderson NL, Zolotarjova NI, Wynn R, Neff NT, Link J, Huber RM, Burn TC, Rupar MJ, Cunningham MR, Selling BH, Ma J, Stern AA, Hollis GF, Stein RB, Friedman PA.

J Biol Chem. 2002 Apr 12;277(15):12970-7. Epub 2001 Dec 31.

23.

Characterization of two genes encoding Bacillus thuringiensis insecticidal crystal proteins toxic to Coleoptera species.

Donovan WP, Rupar MJ, Slaney AC, Malvar T, Gawron-Burke MC, Johnson TB.

Appl Environ Microbiol. 1992 Dec;58(12):3921-7.

24.

Two novel strains of Bacillus thuringiensis toxic to coleopterans.

Rupar MJ, Donovan WP, Groat RG, Slaney AC, Mattison JW, Johnson TB, Charles JF, Dumanoir VC, de Barjac H.

Appl Environ Microbiol. 1991 Nov;57(11):3337-44.

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