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Items: 12

1.

Isoform-specific hyperactivation of calpain-2 occurs presymptomatically at the synapse in Alzheimer's disease mice and correlates with memory deficits in human subjects.

Ahmad F, Das D, Kommaddi RP, Diwakar L, Gowaikar R, Rupanagudi KV, Bennett DA, Ravindranath V.

Sci Rep. 2018 Sep 3;8(1):13119. doi: 10.1038/s41598-018-31073-6.

2.

Reprint of "Dual blockade of the pro-inflammatory chemokine CCL2 and the homeostatic chemokine CXCL12 is as effective as high dose cyclophosphamide in murine proliferative lupus nephritis".

Devarapu SK, Kumar Vr S, Rupanagudi KV, Kulkarni OP, Eulberg D, Klussmann S, Anders HJ.

Clin Immunol. 2017 Dec;185:119-127. doi: 10.1016/j.clim.2017.10.011. Epub 2017 Oct 28.

PMID:
29111236
3.

Reactive Oxygen Species-Mediated Loss of Synaptic Akt1 Signaling Leads to Deficient Activity-Dependent Protein Translation Early in Alzheimer's Disease.

Ahmad F, Singh K, Das D, Gowaikar R, Shaw E, Ramachandran A, Rupanagudi KV, Kommaddi RP, Bennett DA, Ravindranath V.

Antioxid Redox Signal. 2017 Dec 1;27(16):1269-1280. doi: 10.1089/ars.2016.6860. Epub 2017 Apr 12.

4.

Dual blockade of the pro-inflammatory chemokine CCL2 and the homeostatic chemokine CXCL12 is as effective as high dose cyclophosphamide in murine proliferative lupus nephritis.

Devarapu SK, Kumar Vr S, Rupanagudi KV, Kulkarni OP, Eulberg D, Klussmann S, Anders HJ.

Clin Immunol. 2016 Aug;169:139-147. doi: 10.1016/j.clim.2016.07.003. Epub 2016 Jul 5.

PMID:
27392463
5.

Focal adhesion kinase regulates the activity of the osmosensitive transcription factor TonEBP/NFAT5 under hypertonic conditions.

Neuhofer W, Küper C, Lichtnekert J, Holzapfel K, Rupanagudi KV, Fraek ML, Bartels H, Beck FX.

Front Physiol. 2014 Apr 4;5:123. doi: 10.3389/fphys.2014.00123. eCollection 2014.

6.

Cathepsin S inhibition suppresses systemic lupus erythematosus and lupus nephritis because cathepsin S is essential for MHC class II-mediated CD4 T cell and B cell priming.

Rupanagudi KV, Kulkarni OP, Lichtnekert J, Darisipudi MN, Mulay SR, Schott B, Gruner S, Haap W, Hartmann G, Anders HJ.

Ann Rheum Dis. 2015 Feb;74(2):452-63. doi: 10.1136/annrheumdis-2013-203717. Epub 2013 Dec 3.

PMID:
24300027
7.

Calcium oxalate crystals induce renal inflammation by NLRP3-mediated IL-1β secretion.

Mulay SR, Kulkarni OP, Rupanagudi KV, Migliorini A, Darisipudi MN, Vilaysane A, Muruve D, Shi Y, Munro F, Liapis H, Anders HJ.

J Clin Invest. 2013 Jan;123(1):236-46. doi: 10.1172/JCI63679. Epub 2012 Dec 10.

8.

Histones from dying renal cells aggravate kidney injury via TLR2 and TLR4.

Allam R, Scherbaum CR, Darisipudi MN, Mulay SR, Hägele H, Lichtnekert J, Hagemann JH, Rupanagudi KV, Ryu M, Schwarzenberger C, Hohenstein B, Hugo C, Uhl B, Reichel CA, Krombach F, Monestier M, Liapis H, Moreth K, Schaefer L, Anders HJ.

J Am Soc Nephrol. 2012 Aug;23(8):1375-88. doi: 10.1681/ASN.2011111077. Epub 2012 Jun 7.

9.

Anti-GBM glomerulonephritis involves IL-1 but is independent of NLRP3/ASC inflammasome-mediated activation of caspase-1.

Lichtnekert J, Kulkarni OP, Mulay SR, Rupanagudi KV, Ryu M, Allam R, Vielhauer V, Muruve D, Lindenmeyer MT, Cohen CD, Anders HJ.

PLoS One. 2011;6(10):e26778. doi: 10.1371/journal.pone.0026778. Epub 2011 Oct 27.

10.

Activated protein C attenuates systemic lupus erythematosus and lupus nephritis in MRL-Fas(lpr) mice.

Lichtnekert J, Rupanagudi KV, Kulkarni OP, Darisipudi MN, Allam R, Anders HJ.

J Immunol. 2011 Sep 15;187(6):3413-21. doi: 10.4049/jimmunol.1101125. Epub 2011 Aug 17.

11.

Polyene macrolide antifungal drugs trigger interleukin-1β secretion by activating the NLRP3 inflammasome.

Darisipudi MN, Allam R, Rupanagudi KV, Anders HJ.

PLoS One. 2011;6(5):e19588. doi: 10.1371/journal.pone.0019588. Epub 2011 May 23.

12.

Cutting edge: cyclic polypeptide and aminoglycoside antibiotics trigger IL-1β secretion by activating the NLRP3 inflammasome.

Allam R, Darisipudi MN, Rupanagudi KV, Lichtnekert J, Tschopp J, Anders HJ.

J Immunol. 2011 Mar 1;186(5):2714-8. doi: 10.4049/jimmunol.1002657. Epub 2011 Jan 28.

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