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Acute sprint exercise transcriptome in human skeletal muscle.

Rundqvist HC, Montelius A, Osterlund T, Norman B, Esbjornsson M, Jansson E.

PLoS One. 2019 Oct 24;14(10):e0223024. doi: 10.1371/journal.pone.0223024. eCollection 2019.


Doxorubicin-induced skeletal muscle atrophy: Elucidating the underlying molecular pathways.

Hiensch AE, Bolam KA, Mijwel S, Jeneson JAL, Huitema ADR, Kranenburg O, van der Wall E, Rundqvist H, Wengstrom Y, May AM.

Acta Physiol (Oxf). 2019 Oct 10:e13400. doi: 10.1111/apha.13400. [Epub ahead of print] Review.


Effects of Exercise on Chemotherapy Completion and Hospitalization Rates: The OptiTrain Breast Cancer Trial.

Mijwel S, Bolam KA, Gerrevall J, Foukakis T, Wengström Y, Rundqvist H.

Oncologist. 2019 Aug 7. pii: theoncologist.2019-0262. doi: 10.1634/theoncologist.2019-0262. [Epub ahead of print]


Acute and chronic hypoxia differentially predispose lungs for metastases.

Reiterer M, Colaço R, Emrouznejad P, Jensen A, Rundqvist H, Johnson RS, Branco C.

Sci Rep. 2019 Jul 15;9(1):10246. doi: 10.1038/s41598-019-46763-y.


Two-year follow-up of the OptiTrain randomised controlled exercise trial.

Bolam KA, Mijwel S, Rundqvist H, Wengström Y.

Breast Cancer Res Treat. 2019 Jun;175(3):637-648. doi: 10.1007/s10549-019-05204-0. Epub 2019 Mar 26.


High-intensity exercise during chemotherapy induces beneficial effects 12 months into breast cancer survivorship.

Mijwel S, Jervaeus A, Bolam KA, Norrbom J, Bergh J, Rundqvist H, Wengström Y.

J Cancer Surviv. 2019 Apr;13(2):244-256. doi: 10.1007/s11764-019-00747-z. Epub 2019 Mar 25.


Glycolytic Response to Inflammation Over Time: Role of Myeloid HIF-1alpha.

Fitzpatrick SF, Gojkovic M, Macias D, Tegnebratt T, Lu L, Samén E, Rundqvist H, Johnson RS.

Front Physiol. 2018 Nov 22;9:1624. doi: 10.3389/fphys.2018.01624. eCollection 2018.


Exercise training during chemotherapy preserves skeletal muscle fiber area, capillarization, and mitochondrial content in patients with breast cancer.

Mijwel S, Cardinale DA, Norrbom J, Chapman M, Ivarsson N, Wengström Y, Sundberg CJ, Rundqvist H.

FASEB J. 2018 Oct;32(10):5495-5505. doi: 10.1096/fj.201700968R. Epub 2018 May 11.


The Factor Inhibiting HIF Asparaginyl Hydroxylase Regulates Oxidative Metabolism and Accelerates Metabolic Adaptation to Hypoxia.

Sim J, Cowburn AS, Palazon A, Madhu B, Tyrakis PA, Macías D, Bargiela DM, Pietsch S, Gralla M, Evans CE, Kittipassorn T, Chey YCJ, Branco CM, Rundqvist H, Peet DJ, Johnson RS.

Cell Metab. 2018 Apr 3;27(4):898-913.e7. doi: 10.1016/j.cmet.2018.02.020.


Treatment response assessment with (R)-[11CPAQ PET in the MMTV-PyMT mouse model of breast cancer.

Tegnebratt T, Lu L, Eksborg S, Chireh A, Damberg P, Nikkhou-Aski S, Foukakis T, Rundqvist H, Holmin S, Kuiper RV, Samen E.

EJNMMI Res. 2018 Apr 3;8(1):25. doi: 10.1186/s13550-018-0380-x.


Highly favorable physiological responses to concurrent resistance and high-intensity interval training during chemotherapy: the OptiTrain breast cancer trial.

Mijwel S, Backman M, Bolam KA, Olofsson E, Norrbom J, Bergh J, Sundberg CJ, Wengström Y, Rundqvist H.

Breast Cancer Res Treat. 2018 May;169(1):93-103. doi: 10.1007/s10549-018-4663-8. Epub 2018 Jan 18.


Adding high-intensity interval training to conventional training modalities: optimizing health-related outcomes during chemotherapy for breast cancer: the OptiTrain randomized controlled trial.

Mijwel S, Backman M, Bolam KA, Jervaeus A, Sundberg CJ, Margolin S, Browall M, Rundqvist H, Wengström Y.

Breast Cancer Res Treat. 2018 Feb;168(1):79-93. doi: 10.1007/s10549-017-4571-3. Epub 2017 Nov 14.


An HIF-1α/VEGF-A Axis in Cytotoxic T Cells Regulates Tumor Progression.

Palazon A, Tyrakis PA, Macias D, Veliça P, Rundqvist H, Fitzpatrick S, Vojnovic N, Phan AT, Loman N, Hedenfalk I, Hatschek T, Lövrot J, Foukakis T, Goldrath AW, Bergh J, Johnson RS.

Cancer Cell. 2017 Nov 13;32(5):669-683.e5. doi: 10.1016/j.ccell.2017.10.003.


Hypoxic sprint exercise as a complement to the "Live High-Train Low" regimen.

Rundqvist H, Gustafsson T.

Acta Physiol (Oxf). 2018 Jan;222(1). doi: 10.1111/apha.12989. Epub 2017 Dec 5. No abstract available.


Influence of nutrient ingestion on amino acid transporters and protein synthesis in human skeletal muscle after sprint exercise.

Rundqvist HC, Esbjörnsson M, Rooyackers O, Österlund T, Moberg M, Apro W, Blomstrand E, Jansson E.

J Appl Physiol (1985). 2017 Dec 1;123(6):1501-1515. doi: 10.1152/japplphysiol.00244.2017. Epub 2017 Aug 31.


Human cancer-associated fibroblasts enhance glutathione levels and antagonize drug-induced prostate cancer cell death.

Cheteh EH, Augsten M, Rundqvist H, Bianchi J, Sarne V, Egevad L, Bykov VJ, Östman A, Wiman KG.

Cell Death Dis. 2017 Jun 1;8(6):e2848. doi: 10.1038/cddis.2017.225.


A Molecular Mechanism To Switch the Aryl Hydrocarbon Receptor from a Transcription Factor to an E3 Ubiquitin Ligase.

Luecke-Johansson S, Gralla M, Rundqvist H, Ho JC, Johnson RS, Gradin K, Poellinger L.

Mol Cell Biol. 2017 Jun 15;37(13). pii: e00630-16. doi: 10.1128/MCB.00630-16. Print 2017 Jul 1.


Modelling pulmonary microthrombosis coupled to metastasis: distinct effects of thrombogenesis on tumorigenesis.

Evans CE, Palazon A, Sim J, Tyrakis PA, Prodger A, Lu X, Chan S, Bendahl PO, Belting M, Von Euler L, Rundqvist H, Johnson RS, Branco C.

Biol Open. 2017 May 15;6(5):688-697. doi: 10.1242/bio.024653.


[Aerobic and muscle-strengthening exercise should be recommended].

Rundqvist H, Wengström Y.

Lakartidningen. 2017 Feb 14;114. pii: EFHC. Swedish. No abstract available.


Optitrain: a randomised controlled exercise trial for women with breast cancer undergoing chemotherapy.

Wengström Y, Bolam KA, Mijwel S, Sundberg CJ, Backman M, Browall M, Norrbom J, Rundqvist H.

BMC Cancer. 2017 Feb 6;17(1):100. doi: 10.1186/s12885-017-3079-x.


Boosting the hypoxic response in myeloid cells accelerates resolution of fibrosis and regeneration of the liver in mice.

Kantari-Mimoun C, Krzywinska E, Castells M, Milien C, Klose R, Meinecke AK, Lemberger U, Mathivet T, Gojkovic M, Schrödter K, Österreicher C, Fandrey J, Rundqvist H, Stockmann C.

Oncotarget. 2017 Feb 28;8(9):15085-15100. doi: 10.18632/oncotarget.14749.


Physical Activity During and After Adjuvant Treatment for Breast Cancer: An Integrative Review of Women's Experiences.

Browall M, Mijwel S, Rundqvist H, Wengström Y.

Integr Cancer Ther. 2018 Mar;17(1):16-30. doi: 10.1177/1534735416683807. Epub 2016 Dec 23. Review.


Validation of 2 Submaximal Cardiorespiratory Fitness Tests in Patients With Breast Cancer Undergoing Chemotherapy.

Mijwel S, Cardinale D, Ekblom-Bak E, Sundberg CJ, Wengström Y, Rundqvist H.

Rehabil Oncol. 2016 Oct;34(4):137-143. Epub 2016 Oct 14.


Cutaneous exposure to hypoxia does not affect skin perfusion in humans.

Siebenmann C, Keramidas ME, Rundqvist H, Mijwel S, Cowburn AS, Johnson RS, Eiken O.

Acta Physiol (Oxf). 2017 Jul;220(3):361-369. doi: 10.1111/apha.12825. Epub 2016 Nov 30.


Autocrine VEGF Isoforms Differentially Regulate Endothelial Cell Behavior.

Yamamoto H, Rundqvist H, Branco C, Johnson RS.

Front Cell Dev Biol. 2016 Sep 21;4:99. eCollection 2016.


Skeletal muscle hypoxia-inducible factor-1 and exercise.

Lindholm ME, Rundqvist H.

Exp Physiol. 2016 Jan;101(1):28-32. doi: 10.1113/EP085318. Epub 2015 Oct 15. Review.


Role of Tumor Pericytes in the Recruitment of Myeloid-Derived Suppressor Cells.

Hong J, Tobin NP, Rundqvist H, Li T, Lavergne M, García-Ibáñez Y, Qin H, Paulsson J, Zeitelhofer M, Adzemovic MZ, Nilsson I, Roswall P, Hartman J, Johnson RS, Östman A, Bergh J, Poljakovic M, Genové G.

J Natl Cancer Inst. 2015 Aug 21;107(10). pii: djv209. doi: 10.1093/jnci/djv209. Print 2015 Oct. Erratum in: J Natl Cancer Inst. 2016 Mar;108(3). pii: djv434. doi: 10.1093/jnci/djv434.


Rapidly elevated levels of PGC-1α-b protein in human skeletal muscle after exercise: exploring regulatory factors in a randomized controlled trial.

Gidlund EK, Ydfors M, Appel S, Rundqvist H, Sundberg CJ, Norrbom J.

J Appl Physiol (1985). 2015 Aug 15;119(4):374-84. doi: 10.1152/japplphysiol.01000.2014. Epub 2015 Jun 18.


Confrontation of fibroblasts with cancer cells in vitro: gene network analysis of transcriptome changes and differential capacity to inhibit tumor growth.

Alexeyenko A, Alkasalias T, Pavlova T, Szekely L, Kashuba V, Rundqvist H, Wiklund P, Egevad L, Csermely P, Korcsmaros T, Guven H, Klein G.

J Exp Clin Cancer Res. 2015 Jun 18;34:62. doi: 10.1186/s13046-015-0178-x.


An integrative analysis reveals coordinated reprogramming of the epigenome and the transcriptome in human skeletal muscle after training.

Lindholm ME, Marabita F, Gomez-Cabrero D, Rundqvist H, Ekström TJ, Tegnér J, Sundberg CJ.

Epigenetics. 2014 Dec;9(12):1557-69. doi: 10.4161/15592294.2014.982445.


Negative regulation of HIF in skeletal muscle of elite endurance athletes: a tentative mechanism promoting oxidative metabolism.

Lindholm ME, Fischer H, Poellinger L, Johnson RS, Gustafsson T, Sundberg CJ, Rundqvist H.

Am J Physiol Regul Integr Comp Physiol. 2014 Aug 1;307(3):R248-55. doi: 10.1152/ajpregu.00036.2013. Epub 2014 Jun 4.


Visualization of angiogenesis during cancer development in the polyoma middle T breast cancer model: molecular imaging with (R)-[11C]PAQ.

Samén E, Lu L, Mulder J, Thorell JO, Damberg P, Tegnebratt T, Holmgren L, Rundqvist H, Stone-Elander S.

EJNMMI Res. 2014 Mar 26;4(1):17. doi: 10.1186/2191-219X-4-17.


ACTN3 genotype and modulation of skeletal muscle response to exercise in human subjects.

Norman B, Esbjörnsson M, Rundqvist H, Österlund T, Glenmark B, Jansson E.

J Appl Physiol (1985). 2014 May 1;116(9):1197-203. doi: 10.1152/japplphysiol.00557.2013. Epub 2014 Mar 20.


Nutrient ingestion increased mTOR signaling, but not hVps34 activity in human skeletal muscle after sprint exercise.

Rundqvist HC, Lilja MR, Rooyackers O, Odrzywol K, Murray JT, Esbjörnsson M, Jansson E.

Physiol Rep. 2013 Oct;1(5):e00076. doi: 10.1002/phy2.76. Epub 2013 Sep 23.


Effect of acute exercise on prostate cancer cell growth.

Rundqvist H, Augsten M, Strömberg A, Rullman E, Mijwel S, Kharaziha P, Panaretakis T, Gustafsson T, Östman A.

PLoS One. 2013 Jul 5;8(7):e67579. doi: 10.1371/journal.pone.0067579. Print 2013.


Tumour oxygenation: implications for breast cancer prognosis.

Rundqvist H, Johnson RS.

J Intern Med. 2013 Aug;274(2):105-12. doi: 10.1111/joim.12091. Review.


Reduction in plasma leucine after sprint exercise is greater in males than in females.

Esbjörnsson M, Rooyackers O, Norman B, Rundqvist HC, Nowak J, Bülow J, Simonsen L, Jansson E.

Scand J Med Sci Sports. 2012 Jun;22(3):399-409. doi: 10.1111/j.1600-0838.2010.01222.x. Epub 2010 Sep 7.


Aberrant mural cell recruitment to lymphatic vessels and impaired lymphatic drainage in a murine model of pulmonary fibrosis.

Meinecke AK, Nagy N, Lago GD, Kirmse S, Klose R, Schrödter K, Zimmermann A, Helfrich I, Rundqvist H, Theegarten D, Anhenn O, Orian-Rousseau V, Johnson RS, Alitalo K, Fischer JW, Fandrey J, Stockmann C.

Blood. 2012 Jun 14;119(24):5931-42. doi: 10.1182/blood-2011-12-396895. Epub 2012 Apr 30.


Fibroblasts--a key host cell type in tumor initiation, progression, and metastasis.

Strell C, Rundqvist H, Ostman A.

Ups J Med Sci. 2012 May;117(2):187-95. doi: 10.3109/03009734.2012.654859. Epub 2012 Apr 17.


Targeting of distinct signaling cascades and cancer-associated fibroblasts define the efficacy of Sorafenib against prostate cancer cells.

Kharaziha P, Rodriguez P, Li Q, Rundqvist H, Björklund AC, Augsten M, Ullén A, Egevad L, Wiklund P, Nilsson S, Kroemer G, Grander D, Panaretakis T.

Cell Death Dis. 2012 Jan 26;3:e262. doi: 10.1038/cddis.2012.1.


Sprint exercise enhances skeletal muscle p70S6k phosphorylation and more so in women than in men.

Esbjörnsson M, Rundqvist HC, Mascher H, Österlund T, Rooyackers O, Blomstrand E, Jansson E.

Acta Physiol (Oxf). 2012 Jul;205(3):411-22. doi: 10.1111/j.1748-1716.2012.02404.x. Epub 2012 Jan 23.


Alternative splice variant PGC-1α-b is strongly induced by exercise in human skeletal muscle.

Norrbom J, Sällstedt EK, Fischer H, Sundberg CJ, Rundqvist H, Gustafsson T.

Am J Physiol Endocrinol Metab. 2011 Dec;301(6):E1092-8. doi: 10.1152/ajpendo.00119.2011. Epub 2011 Aug 23.


Hypoxia and metastasis in breast cancer.

Rundqvist H, Johnson RS.

Curr Top Microbiol Immunol. 2010;345:121-39. doi: 10.1007/82_2010_77. Review.


Training response of mitochondrial transcription factors in human skeletal muscle.

Norrbom J, Wallman SE, Gustafsson T, Rundqvist H, Jansson E, Sundberg CJ.

Acta Physiol (Oxf). 2010 Jan;198(1):71-9. doi: 10.1111/j.1748-1716.2009.02030.x. Epub 2009 Aug 13.


Activation of the erythropoietin receptor in human skeletal muscle.

Rundqvist H, Rullman E, Sundberg CJ, Fischer H, Eisleitner K, Ståhlberg M, Sundblad P, Jansson E, Gustafsson T.

Eur J Endocrinol. 2009 Sep;161(3):427-34. doi: 10.1530/EJE-09-0342. Epub 2009 Jun 10.


Strength, power, fiber types, and mRNA expression in trained men and women with different ACTN3 R577X genotypes.

Norman B, Esbjörnsson M, Rundqvist H, Osterlund T, von Walden F, Tesch PA.

J Appl Physiol (1985). 2009 Mar;106(3):959-65. doi: 10.1152/japplphysiol.91435.2008. Epub 2009 Jan 15.


Endurance exercise activates matrix metalloproteinases in human skeletal muscle.

Rullman E, Norrbom J, Strömberg A, Wågsäter D, Rundqvist H, Haas T, Gustafsson T.

J Appl Physiol (1985). 2009 Mar;106(3):804-12. doi: 10.1152/japplphysiol.90872.2008. Epub 2009 Jan 8.


HIF-1alpha in endurance training: suppression of oxidative metabolism.

Mason SD, Rundqvist H, Papandreou I, Duh R, McNulty WJ, Howlett RA, Olfert IM, Sundberg CJ, Denko NC, Poellinger L, Johnson RS.

Am J Physiol Regul Integr Comp Physiol. 2007 Nov;293(5):R2059-69. Epub 2007 Sep 12.


The influence of physical training on the angiopoietin and VEGF-A systems in human skeletal muscle.

Gustafsson T, Rundqvist H, Norrbom J, Rullman E, Jansson E, Sundberg CJ.

J Appl Physiol (1985). 2007 Sep;103(3):1012-20. Epub 2007 Jun 14.


A single bout of exercise activates matrix metalloproteinase in human skeletal muscle.

Rullman E, Rundqvist H, Wågsäter D, Fischer H, Eriksson P, Sundberg CJ, Jansson E, Gustafsson T.

J Appl Physiol (1985). 2007 Jun;102(6):2346-51. Epub 2007 Jan 25.

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