Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 82

1.

Imepitoin Shows Benzodiazepine-Like Effects in Models of Anxiety.

Engel O, Masic A, Landsberg G, Brooks M, Mills DS, Rundfeldt C.

Front Pharmacol. 2018 Nov 1;9:1225. doi: 10.3389/fphar.2018.01225. eCollection 2018.

2.

Clinical evaluation of a combination therapy of imepitoin with phenobarbital in dogs with refractory idiopathic epilepsy.

Neßler J, Rundfeldt C, Löscher W, Kostic D, Keefe T, Tipold A.

BMC Vet Res. 2017 Jan 25;13(1):33. doi: 10.1186/s12917-017-0957-z.

3.

Quality of life of dogs with chronic epilepsy.

Rundfeldt C.

Vet Rec. 2016 Jun 25;178(26):650-1. doi: 10.1136/vr.i3444. No abstract available.

PMID:
27339925
4.
5.

Ubiquitin is a versatile scaffold protein for the generation of molecules with de novo binding and advantageous drug-like properties.

Job F, Settele F, Lorey S, Rundfeldt C, Baumann L, Beck-Sickinger AG, Haupts U, Lilie H, Bosse-Doenecke E.

FEBS Open Bio. 2015 Jul 10;5:579-93. doi: 10.1016/j.fob.2015.07.002. eCollection 2015.

6.

Evaluation of the efficacy of meloxicam for post-operative management of pain and inflammation in horses after orthopaedic surgery in a placebo controlled clinical field trial.

Walliser U, Fenner A, Mohren N, Keefe T, deVries F, Rundfeldt C.

BMC Vet Res. 2015 May 15;11:113. doi: 10.1186/s12917-015-0427-4.

7.

Activity and Safety of Inhaled Itraconazole Nanosuspension in a Model Pulmonary Aspergillus fumigatus Infection in Inoculated Young Quails.

Wlaź P, Knaga S, Kasperek K, Wlaź A, Poleszak E, Jeżewska-Witkowska G, Winiarczyk S, Wyska E, Heinekamp T, Rundfeldt C.

Mycopathologia. 2015 Aug;180(1-2):35-42. doi: 10.1007/s11046-015-9885-2. Epub 2015 Mar 20.

8.

Anxiogenic- and antidepressant-like behavior in corneally kindled rats.

Wlaź P, Poleszak E, Serefko A, Wlaź A, Rundfeldt C.

Pharmacol Rep. 2015 Apr;67(2):349-52. doi: 10.1016/j.pharep.2014.10.012. Epub 2014 Oct 29.

PMID:
25712662
9.

Clinical efficacy and safety of imepitoin in comparison with phenobarbital for the control of idiopathic epilepsy in dogs.

Tipold A, Keefe TJ, Löscher W, Rundfeldt C, de Vries F.

J Vet Pharmacol Ther. 2015 Apr;38(2):160-8. doi: 10.1111/jvp.12151. Epub 2014 Jul 31.

PMID:
25079881
10.

Imepitoin as novel treatment option for canine idiopathic epilepsy: pharmacokinetics, distribution, and metabolism in dogs.

Rundfeldt C, Gasparic A, Wlaź P.

J Vet Pharmacol Ther. 2014 Oct;37(5):421-34. doi: 10.1111/jvp.12117. Epub 2014 Mar 10.

11.

Novel ubiquitin-derived high affinity binding proteins with tumor targeting properties.

Lorey S, Fiedler E, Kunert A, Nerkamp J, Lange C, Fiedler M, Bosse-Doenecke E, Meysing M, Gloser M, Rundfeldt C, Rauchhaus U, Hänssgen I, Göttler T, Steuernagel A, Fiedler U, Haupts U.

J Biol Chem. 2014 Mar 21;289(12):8493-507. doi: 10.1074/jbc.M113.519884. Epub 2014 Jan 28.

12.

The pharmacology of imepitoin: the first partial benzodiazepine receptor agonist developed for the treatment of epilepsy.

Rundfeldt C, Löscher W.

CNS Drugs. 2014 Jan;28(1):29-43. doi: 10.1007/s40263-013-0129-z. Review.

PMID:
24357084
13.

A model for treating avian aspergillosis: serum and lung tissue kinetics for Japanese quail (Coturnix japonica) following single and multiple aerosol exposures of a nanoparticulate itraconazole suspension.

Rundfeldt C, Wyska E, Steckel H, Witkowski A, Jeżewska-Witkowska G, Wlaź P.

Med Mycol. 2013 Nov;51(8):800-10. doi: 10.3109/13693786.2013.803166. Epub 2013 Jul 2.

PMID:
23815436
14.

Inhalable highly concentrated itraconazole nanosuspension for the treatment of bronchopulmonary aspergillosis.

Rundfeldt C, Steckel H, Scherliess H, Wyska E, Wlaź P.

Eur J Pharm Biopharm. 2013 Jan;83(1):44-53. doi: 10.1016/j.ejpb.2012.09.018. Epub 2012 Oct 12.

PMID:
23064325
15.
16.

The atypical anxiolytic drug, tofisopam, selectively blocks phosphodiesterase isoenzymes and is active in the mouse model of negative symptoms of psychosis.

Rundfeldt C, Socała K, Wlaź P.

J Neural Transm (Vienna). 2010 Nov;117(11):1319-25. doi: 10.1007/s00702-010-0507-3. Epub 2010 Oct 22.

17.

Effects of sarcosine, a glycine transporter type 1 inhibitor, in two mouse seizure models.

Socała K, Nieoczym D, Rundfeldt C, Wlaź P.

Pharmacol Rep. 2010 Mar-Apr;62(2):392-7.

18.

Effects of sildenafil on pentylenetetrazol-induced convulsions in mice and amygdala-kindled seizures in rats.

Nieoczym D, Socała K, Rundfeldt C, Wlaź P.

Pharmacol Rep. 2010 Mar-Apr;62(2):383-91.

19.

The putative lipid raft modulator miltefosine displays immunomodulatory action in T-cell dependent dermal inflammation models.

Bäumer W, Wlaź P, Jennings G, Rundfeldt C.

Eur J Pharmacol. 2010 Feb 25;628(1-3):226-32. doi: 10.1016/j.ejphar.2009.11.018. Epub 2009 Nov 14.

PMID:
19917276
20.

Highly selective phosphodiesterase 4 inhibitors for the treatment of allergic skin diseases and psoriasis.

Bäumer W, Hoppmann J, Rundfeldt C, Kietzmann M.

Inflamm Allergy Drug Targets. 2007 Mar;6(1):17-26. Review.

PMID:
17352685
21.

New GABA-modulating 1,2,4-oxadiazole derivatives and their anticonvulsant activity.

Lankau HJ, Unverferth K, Grunwald C, Hartenhauer H, Heinecke K, Bernöster K, Dost R, Egerland U, Rundfeldt C.

Eur J Med Chem. 2007 Jun;42(6):873-9. Epub 2007 Jan 12.

PMID:
17303289
22.

ELB139 an agonist at the benzodiazepine binding site increases 5-HT in the striatum and prefrontal cortex of rats: a microdialysis study.

Langen B, Rundfeldt C.

Pharmacol Biochem Behav. 2007 Jan;86(1):79-85. Epub 2006 Dec 22.

PMID:
17257662
23.

Retigabine.

Porter RJ, Nohria V, Rundfeldt C.

Neurotherapeutics. 2007 Jan;4(1):149-54. Review.

PMID:
17199031
24.

The novel anxiolytic ELB139 displays selectivity to recombinant GABA(A) receptors different from diazepam.

Rabe H, Kronbach C, Rundfeldt C, Lüddens H.

Neuropharmacology. 2007 Mar;52(3):796-801. Epub 2006 Nov 7.

PMID:
17087982
25.

Antidystonic effects of Kv7 (KCNQ) channel openers in the dt sz mutant, an animal model of primary paroxysmal dystonia.

Richter A, Sander SE, Rundfeldt C.

Br J Pharmacol. 2006 Nov;149(6):747-53. Epub 2006 Oct 3.

26.

Synthesis, pharmacology, and structure-activity relationships of novel imidazolones and pyrrolones as modulators of GABAA receptors.

Grunwald C, Rundfeldt C, Lankau HJ, Arnold T, Höfgen N, Dost R, Egerland U, Hofmann HJ, Unverferth K.

J Med Chem. 2006 Mar 23;49(6):1855-66.

PMID:
16539371
27.
28.

Anticonvulsant activity and tolerance of ELB138 in dogs with epilepsy: a clinical pilot study.

Rieck S, Rundfeldt C, Tipold A.

Vet J. 2006 Jul;172(1):86-95.

PMID:
15905110
29.

Characterization in rats of the anxiolytic potential of ELB139 [1-(4-chlorophenyl)-4-piperidin-1-yl-1,5-dihydro-imidazol-2-on], a new agonist at the benzodiazepine binding site of the GABAA receptor.

Langen B, Egerland U, Bernöster K, Dost R, Unverferth K, Rundfeldt C.

J Pharmacol Exp Ther. 2005 Aug;314(2):717-24. Epub 2005 Apr 28.

PMID:
15860576
31.

The anti-hyperalgesic activity of retigabine is mediated by KCNQ potassium channel activation.

Dost R, Rostock A, Rundfeldt C.

Naunyn Schmiedebergs Arch Pharmacol. 2004 Apr;369(4):382-90. Epub 2004 Mar 9.

PMID:
15007538
33.

AWD 12-281, a highly selective phosphodiesterase 4 inhibitor, is effective in the prevention and treatment of inflammatory reactions in a model of allergic dermatitis.

Bäumer W, Gorr G, Hoppmann J, Ehinger AM, Rundfeldt C, Kietzmann M.

J Pharm Pharmacol. 2003 Aug;55(8):1107-14.

PMID:
12956900
34.
35.

Effects of retigabine on rhythmic synchronous activity of human neocortical slices.

Straub H, Köhling R, Höhling J, Rundfeldt C, Tuxhorn I, Ebner A, Wolf P, Pannek H, Speckmann E.

Epilepsy Res. 2001 May;44(2-3):155-65.

PMID:
11325571
37.

A neurochemical study of the novel antiepileptic drug retigabine in mouse brain.

Sills GJ, Rundfeldt C, Butler E, Forrest G, Thompson GG, Brodie MJ.

Pharmacol Res. 2000 Dec;42(6):553-7.

PMID:
11058408
38.

Flupirtine and retigabine prevent L-glutamate toxicity in rat pheochromocytoma PC 12 cells.

Seyfried J, Evert BO, Rundfeldt C, Schulz JB, Kovar KA, Klockgether T, Wüllner U.

Eur J Pharmacol. 2000 Jul 21;400(2-3):155-66.

PMID:
10988329
39.
41.

Retigabine strongly reduces repetitive firing in rat entorhinal cortex.

Hetka R, Rundfeldt C, Heinemann U, Schmitz D.

Eur J Pharmacol. 1999 Dec 15;386(2-3):165-71.

PMID:
10618466
43.

Synthesis and anticonvulsant activity of new 4-aminopyrazoles and 5-aminopyrazol-3-ones.

Lankau HJ, Menzer M, Rostock A, Arnold T, Rundfeldt C, Unverferth K.

Pharmazie. 1999 Sep;54(9):705-6. No abstract available.

PMID:
10522275
44.

3-Amino- and 5-aminopyrazoles with anticonvulsant activity.

Lankau HJ, Menzer M, Rostock A, Arnold T, Rundfeldt C, Unverferth K.

Arch Pharm (Weinheim). 1999 Jun;332(6):219-21.

PMID:
10399492
45.
47.
48.
50.

Supplemental Content

Loading ...
Support Center