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Items: 1 to 50 of 53

1.

Analysis of endogenous peptides released from osteoarthritic cartilage unravels novel pathogenic markers.

Fernandez-Puente P, González-Rodríguez L, Calamia V, Picchi F, Lourido L, Camacho-Encina M, Oreiro N, Rocha B, Paz R, Marina A, García C, Blanco FJ, Ruiz-Romero C.

Mol Cell Proteomics. 2019 Jul 27. pii: mcp.RA119.001554. doi: 10.1074/mcp.RA119.001554. [Epub ahead of print]

2.

Anti-Inflammatory Effects of Novel Standardized Platelet Rich Plasma Releasates on Knee Osteoarthritic Chondrocytes and Cartilage in Vitro.

Gato-Calvo L, Hermida-Gomez T, Ruiz Romero C, Burguera EF, Blanco FJ.

Curr Pharm Biotechnol. 2019 Jun 19. doi: 10.2174/1389201020666190619111118. [Epub ahead of print]

PMID:
31237204
3.

Platelet-rich plasma in osteoarthritis treatment: review of current evidence.

Gato-Calvo L, Magalhaes J, Ruiz-Romero C, Blanco FJ, Burguera EF.

Ther Adv Chronic Dis. 2019 Feb 19;10:2040622319825567. doi: 10.1177/2040622319825567. eCollection 2019. Review.

4.

What did we learn from 'omics' studies in osteoarthritis.

Ruiz-Romero C, Rego-Perez I, Blanco FJ.

Curr Opin Rheumatol. 2018 Jan;30(1):114-120. doi: 10.1097/BOR.0000000000000460. Review.

PMID:
29035928
5.

Defining the proteomic landscape of rheumatoid arthritis: progress and prospective clinical applications.

Lourido L, Blanco FJ, Ruiz-Romero C.

Expert Rev Proteomics. 2017 May;14(5):431-444. doi: 10.1080/14789450.2017.1321481. Epub 2017 May 2. Review.

PMID:
28425787
6.

Screening and Validation of Novel Biomarkers in Osteoarticular Pathologies by Comprehensive Combination of Protein Array Technologies.

Sierra-Sánchez Á, Garrido-Martín D, Lourido L, González-González M, Díez P, Ruiz-Romero C, Sjöber R, Droste C, De Las Rivas J, Nilsson P, Blanco F, Fuentes M.

J Proteome Res. 2017 May 5;16(5):1890-1899. doi: 10.1021/acs.jproteome.6b00980. Epub 2017 Apr 17.

PMID:
28379711
7.

Discovery of circulating proteins associated to knee radiographic osteoarthritis.

Lourido L, Ayoglu B, Fernández-Tajes J, Oreiro N, Henjes F, Hellström C, Schwenk JM, Ruiz-Romero C, Nilsson P, Blanco FJ.

Sci Rep. 2017 Mar 9;7(1):137. doi: 10.1038/s41598-017-00195-8.

8.

Mass spectrometry imaging: a novel technology in rheumatology.

Rocha B, Ruiz-Romero C, Blanco FJ.

Nat Rev Rheumatol. 2017 Jan;13(1):52-63. doi: 10.1038/nrrheum.2016.184. Epub 2016 Nov 24. Review.

PMID:
27881864
9.

Multiplexed mass spectrometry monitoring of biomarker candidates for osteoarthritis.

Fernández-Puente P, Calamia V, González-Rodríguez L, Lourido L, Camacho-Encina M, Oreiro N, Ruiz-Romero C, Blanco FJ.

J Proteomics. 2017 Jan 30;152:216-225. doi: 10.1016/j.jprot.2016.11.012. Epub 2016 Nov 16.

PMID:
27865793
10.

MALDI mass spectrometry imaging in rheumatic diseases.

Rocha B, Cillero-Pastor B, Blanco FJ, Ruiz-Romero C.

Biochim Biophys Acta Proteins Proteom. 2017 Jul;1865(7):784-794. doi: 10.1016/j.bbapap.2016.10.004. Epub 2016 Oct 11. Review.

PMID:
27742553
11.

Identification of Factors Produced and Secreted by Mesenchymal Stromal Cells with the SILAC Method.

Rocha B, Calamia V, Blanco FJ, Ruiz-Romero C.

Methods Mol Biol. 2016;1416:551-65. doi: 10.1007/978-1-4939-3584-0_33.

PMID:
27236695
12.

A double-blind, randomized, cross-over, placebo-controlled, pilot trial with Sativex in Huntington's disease.

López-Sendón Moreno JL, García Caldentey J, Trigo Cubillo P, Ruiz Romero C, García Ribas G, Alonso Arias MA, García de Yébenes MJ, Tolón RM, Galve-Roperh I, Sagredo O, Valdeolivas S, Resel E, Ortega-Gutierrez S, García-Bermejo ML, Fernández Ruiz J, Guzmán M, García de Yébenes Prous J.

J Neurol. 2016 Jul;263(7):1390-400. doi: 10.1007/s00415-016-8145-9. Epub 2016 May 9.

PMID:
27159993
13.

Lessons from the proteomic study of osteoarthritis.

Ruiz-Romero C, Fernández-Puente P, Calamia V, Blanco FJ.

Expert Rev Proteomics. 2015 Aug;12(4):433-43. doi: 10.1586/14789450.2015.1065182. Epub 2015 Jul 7. Review.

PMID:
26152498
14.

Integrating medical and research information: a big data approach.

Tilve Álvarez CM, Ayora Pais A, Ruíz Romero C, Llamas Gómez D, Carrajo García L, Blanco García FJ, Vázquez González G.

Stud Health Technol Inform. 2015;210:707-11.

PMID:
25991244
15.

Secretome analysis of human articular chondrocytes unravels catabolic effects of nicotine on the joint.

Lourido L, Calamia V, Fernández-Puente P, Mateos J, Oreiro N, Blanco FJ, Ruiz-Romero C.

Proteomics Clin Appl. 2016 Jun;10(6):671-80. doi: 10.1002/prca.201400186. Epub 2015 Jun 15.

PMID:
25914226
16.

The Spanish biology/disease initiative within the human proteome project: Application to rheumatic diseases.

Ruiz-Romero C, Calamia V, Albar JP, Casal JI, Corrales FJ, Fernández-Puente P, Gil C, Mateos J, Vivanco F, Blanco FJ.

J Proteomics. 2015 Sep 8;127(Pt B):406-13. doi: 10.1016/j.jprot.2015.01.023. Epub 2015 Feb 14. Review.

PMID:
25686859
17.

Quantitative proteomic profiling of human articular cartilage degradation in osteoarthritis.

Lourido L, Calamia V, Mateos J, Fernández-Puente P, Fernández-Tajes J, Blanco FJ, Ruiz-Romero C.

J Proteome Res. 2014 Dec 5;13(12):6096-106. doi: 10.1021/pr501024p. Epub 2014 Nov 21.

PMID:
25383958
18.

Characterization of lipidic markers of chondrogenic differentiation using mass spectrometry imaging.

Rocha B, Cillero-Pastor B, Eijkel G, Bruinen AL, Ruiz-Romero C, Heeren RM, Blanco FJ.

Proteomics. 2015 Feb;15(4):702-13. doi: 10.1002/pmic.201400260. Epub 2015 Jan 3.

PMID:
25346268
19.

Analysis of autoantibody profiles in osteoarthritis using comprehensive protein array concepts.

Henjes F, Lourido L, Ruiz-Romero C, Fernández-Tajes J, Schwenk JM, Gonzalez-Gonzalez M, Blanco FJ, Nilsson P, Fuentes M.

J Proteome Res. 2014 Nov 7;13(11):5218-29. doi: 10.1021/pr500775a. Epub 2014 Oct 9.

PMID:
25227461
20.

A pharmacoproteomic study confirms the synergistic effect of chondroitin sulfate and glucosamine.

Calamia V, Mateos J, Fernández-Puente P, Lourido L, Rocha B, Fernández-Costa C, Montell E, Vergés J, Ruiz-Romero C, Blanco FJ.

Sci Rep. 2014 Jun 10;4:5069. doi: 10.1038/srep05069.

21.

Sequential depletion coupled to C18 sequential extraction as a rapid tool for human serum multiple profiling.

Fernández-Costa C, Reboiro-Jato M, Fdez-Riverola F, Ruiz-Romero C, Blanco FJ, Capelo-Martínez JL.

Talanta. 2014 Jul;125:189-95. doi: 10.1016/j.talanta.2014.02.050. Epub 2014 Feb 28.

PMID:
24840432
22.

LC-MALDI-TOF/TOF for shotgun proteomics.

Fernández-Puente P, Mateos J, Blanco FJ, Ruiz-Romero C.

Methods Mol Biol. 2014;1156:27-38. doi: 10.1007/978-1-4939-0685-7_2.

PMID:
24791979
23.

Cryoconservation of peptide extracts from trypsin digestion of proteins for proteomic analysis in a hospital biobank facility.

Mateos J, Pintor-Iglesias A, Fernández-Puente P, García-Camba M, Ruiz-Romero C, Doménech N, Blanco FJ.

J Proteome Res. 2014 Apr 4;13(4):1930-7. doi: 10.1021/pr401046u. Epub 2014 Mar 3.

PMID:
24521361
24.

Secretome analysis of human mesenchymal stem cells undergoing chondrogenic differentiation.

Rocha B, Calamia V, Casas V, Carrascal M, Blanco FJ, Ruiz-Romero C.

J Proteome Res. 2014 Feb 7;13(2):1045-54. doi: 10.1021/pr401030n. Epub 2014 Jan 15.

PMID:
24400832
25.

Surfing transcriptomic landscapes. A step beyond the annotation of chromosome 16 proteome.

Segura V, Medina-Aunon JA, Mora MI, Martínez-Bartolomé S, Abian J, Aloria K, Antúnez O, Arizmendi JM, Azkargorta M, Barceló-Batllori S, Beaskoetxea J, Bech-Serra JJ, Blanco F, Monteiro MB, Cáceres D, Canals F, Carrascal M, Casal JI, Clemente F, Colomé N, Dasilva N, Díaz P, Elortza F, Fernández-Puente P, Fuentes M, Gallardo O, Gharbi SI, Gil C, González-Tejedo C, Hernáez ML, Lombardía M, Lopez-Lucendo M, Marcilla M, Mato JM, Mendes M, Oliveira E, Orera I, Pascual-Montano A, Prieto G, Ruiz-Romero C, Sánchez del Pino MM, Tabas-Madrid D, Valero ML, Vialas V, Villanueva J, Albar JP, Corrales FJ.

J Proteome Res. 2014 Jan 3;13(1):158-72. doi: 10.1021/pr400721r. Epub 2013 Nov 5.

PMID:
24138474
26.

An assessment of the indirect high intensity ultrasonic assisted cleavage of complex proteomes with immobilized trypsin.

Fernández-Costa C, Ruiz-Romero C, Blanco FJ, Santos HM, Capelo JL.

Talanta. 2013 Mar 15;106:163-8. doi: 10.1016/j.talanta.2012.12.022. Epub 2012 Dec 22.

PMID:
23598111
27.

Achievements and challenges of proteomics in the study of rheumatoid arthritis.

Ruiz-Romero C, Blanco FJ.

Curr Top Med Chem. 2013;13(6):732-42. Review.

PMID:
23574522
28.

New targets for disease modifying osteoarthritis drugs: chondrogenesis and Runx1.

Blanco FJ, Ruiz-Romero C.

Ann Rheum Dis. 2013 May;72(5):631-4. doi: 10.1136/annrheumdis-2012-202652. Epub 2013 Feb 26. No abstract available.

PMID:
23444194
29.

Secretome analysis of chondroitin sulfate-treated chondrocytes reveals anti-angiogenic, anti-inflammatory and anti-catabolic properties.

Calamia V, Lourido L, Fernández-Puente P, Mateos J, Rocha B, Montell E, Vergés J, Ruiz-Romero C, Blanco FJ.

Arthritis Res Ther. 2012 Oct 2;14(5):R202. doi: 10.1186/ar4040.

30.

Metabolic labeling of human bone marrow mesenchymal stem cells for the quantitative analysis of their chondrogenic differentiation.

Rocha B, Calamia V, Mateos J, Fernández-Puente P, Blanco FJ, Ruiz-Romero C.

J Proteome Res. 2012 Nov 2;11(11):5350-61. doi: 10.1021/pr300572r. Epub 2012 Oct 3.

PMID:
22989065
31.

Sequential depletion of human serum for the search of osteoarthritis biomarkers.

Fernández-Costa C, Calamia V, Fernández-Puente P, Capelo-Martínez JL, Ruiz-Romero C, Blanco FJ.

Proteome Sci. 2012 Sep 12;10(1):55. doi: 10.1186/1477-5956-10-55.

32.

Osteoarthritis: Metabolomic characterization of metabolic phenotypes in OA.

Blanco FJ, Ruiz-Romero C.

Nat Rev Rheumatol. 2012 Feb 7;8(3):130-2. doi: 10.1038/nrrheum.2012.11. No abstract available.

PMID:
22310187
33.

Differential protein profiling of synovial fluid from rheumatoid arthritis and osteoarthritis patients using LC-MALDI TOF/TOF.

Mateos J, Lourido L, Fernández-Puente P, Calamia V, Fernández-López C, Oreiro N, Ruiz-Romero C, Blanco FJ.

J Proteomics. 2012 Jun 6;75(10):2869-78. doi: 10.1016/j.jprot.2011.12.042. Epub 2012 Jan 8.

PMID:
22245418
34.

Pharmacoproteomic study of three different chondroitin sulfate compounds on intracellular and extracellular human chondrocyte proteomes.

Calamia V, Fernández-Puente P, Mateos J, Lourido L, Rocha B, Montell E, Vergés J, Ruiz-Romero C, Blanco FJ.

Mol Cell Proteomics. 2012 Jun;11(6):M111.013417. doi: 10.1074/mcp.M111.013417. Epub 2011 Dec 27.

35.

Hsp90β inhibition modulates nitric oxide production and nitric oxide-induced apoptosis in human chondrocytes.

Calamia V, de Andrés MC, Oreiro N, Ruiz-Romero C, Blanco FJ.

BMC Musculoskelet Disord. 2011 Oct 17;12:237. doi: 10.1186/1471-2474-12-237.

36.

A comparison of depletion versus equalization for reducing high-abundance proteins in human serum.

Fernández C, Santos HM, Ruíz-Romero C, Blanco FJ, Capelo-Martínez JL.

Electrophoresis. 2011 Nov;32(21):2966-74. doi: 10.1002/elps.201100183. Epub 2011 Oct 14.

PMID:
21997478
37.

Identification of a panel of novel serum osteoarthritis biomarkers.

Fernández-Puente P, Mateos J, Fernández-Costa C, Oreiro N, Fernández-López C, Ruiz-Romero C, Blanco FJ.

J Proteome Res. 2011 Nov 4;10(11):5095-101. doi: 10.1021/pr200695p. Epub 2011 Oct 19.

PMID:
21973172
38.

Dimethylarginine dimethylaminohydrolase 2, a newly identified mitochondrial protein modulating nitric oxide synthesis in normal human chondrocytes.

Cillero-Pastor B, Mateos J, Fernández-López C, Oreiro N, Ruiz-Romero C, Blanco FJ.

Arthritis Rheum. 2012 Jan;64(1):204-12. doi: 10.1002/art.30652.

39.

Metabolic labeling of chondrocytes for the quantitative analysis of the interleukin-1-beta-mediated modulation of their intracellular and extracellular proteomes.

Calamia V, Rocha B, Mateos J, Fernández-Puente P, Ruiz-Romero C, Blanco FJ.

J Proteome Res. 2011 Aug 5;10(8):3701-11. doi: 10.1021/pr200331k. Epub 2011 Jul 5.

PMID:
21692455
40.

The role of mitochondria in osteoarthritis.

Blanco FJ, Rego I, Ruiz-Romero C.

Nat Rev Rheumatol. 2011 Mar;7(3):161-9. doi: 10.1038/nrrheum.2010.213. Epub 2011 Jan 4. Review.

PMID:
21200395
41.

A Block-matching based technique for the analysis of 2D gel images.

Freire A, Seoane JA, Rodríguez A, Ruiz-Romero C, López-Campos G, Dorado J.

Stud Health Technol Inform. 2010;160(Pt 2):1282-6.

PMID:
20841891
42.

Pharmacoproteomic study of the effects of chondroitin and glucosamine sulfate on human articular chondrocytes.

Calamia V, Ruiz-Romero C, Rocha B, Fernández-Puente P, Mateos J, Montell E, Vergés J, Blanco FJ.

Arthritis Res Ther. 2010;12(4):R138. doi: 10.1186/ar3077. Epub 2010 Jul 13.

43.

Hypoxia conditions differentially modulate human normal and osteoarthritic chondrocyte proteomes.

Ruiz-Romero C, Calamia V, Rocha B, Mateos J, Fernández-Puente P, Blanco FJ.

J Proteome Res. 2010 Jun 4;9(6):3035-45. doi: 10.1021/pr901209s.

PMID:
20387907
44.

Proteomic analysis by two-dimensional electrophoresis to identify the normal human chondrocyte proteome stimulated by tumor necrosis factor alpha and interleukin-1beta.

Cillero-Pastor B, Ruiz-Romero C, Caramés B, López-Armada MJ, Blanco FJ.

Arthritis Rheum. 2010 Mar;62(3):802-14. doi: 10.1002/art.27265.

45.

Strategies to optimize two-dimensional gel electrophoresis analysis of the human joint proteome.

Ruiz-Romero C, Calamia V, Carreira V, Mateos J, Fernández P, Blanco FJ.

Talanta. 2010 Feb 15;80(4):1552-60. doi: 10.1016/j.talanta.2009.05.022. Epub 2009 May 22.

PMID:
20082814
46.

Proteomics role in the search for improved diagnosis, prognosis and treatment of osteoarthritis.

Ruiz-Romero C, Blanco FJ.

Osteoarthritis Cartilage. 2010 Apr;18(4):500-9. doi: 10.1016/j.joca.2009.11.012. Epub 2009 Dec 23. Review.

47.

Mitochondrial proteomics and its application in biomedical research.

Ruiz-Romero C, Blanco FJ.

Mol Biosyst. 2009 Oct;5(10):1130-42. doi: 10.1039/b906296n. Epub 2009 Aug 3. Review.

PMID:
19756302
48.

The role of proteomics in osteoarthritis pathogenesis research.

Ruiz-Romero C, Blanco FJ.

Curr Drug Targets. 2009 Jun;10(6):543-56. Review.

PMID:
19519357
49.

Mitochondrial dysregulation of osteoarthritic human articular chondrocytes analyzed by proteomics: a decrease in mitochondrial superoxide dismutase points to a redox imbalance.

Ruiz-Romero C, Calamia V, Mateos J, Carreira V, Martínez-Gomariz M, Fernández M, Blanco FJ.

Mol Cell Proteomics. 2009 Jan;8(1):172-89. doi: 10.1074/mcp.M800292-MCP200. Epub 2008 Sep 9.

50.

Proteomic analysis of human osteoarthritic chondrocytes reveals protein changes in stress and glycolysis.

Ruiz-Romero C, Carreira V, Rego I, Remeseiro S, López-Armada MJ, Blanco FJ.

Proteomics. 2008 Feb;8(3):495-507. doi: 10.1002/pmic.200700249.

PMID:
18186017

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