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Items: 1 to 50 of 137

1.

NLRP3 inflammasome suppression improves longevity and prevents cardiac aging in male mice.

Marín-Aguilar F, Lechuga-Vieco AV, Alcocer-Gómez E, Castejón-Vega B, Lucas J, Garrido C, Peralta-Garcia A, Pérez-Pulido AJ, Varela-López A, Quiles JL, Ryffel B, Flores I, Bullón P, Ruiz-Cabello J, Cordero MD.

Aging Cell. 2019 Oct 18:e13050. doi: 10.1111/acel.13050. [Epub ahead of print]

2.

NLRP3 inflammasome inhibition by MCC950 in aged mice improves health via enhanced autophagy and PPARα activity.

Marín-Aguilar F, Castejón-Vega B, Alcocer-Gómez E, Lendines-Cordero D, Cooper MA, de la Cruz P, Andújar-Pulido E, Pérez-Alegre M, Muntané J, Pérez-Pulido AJ, Ryffel B, Robertson AAB, Ruiz-Cabello J, Bullón P, Cordero MD.

J Gerontol A Biol Sci Med Sci. 2019 Oct 11. pii: glz239. doi: 10.1093/gerona/glz239. [Epub ahead of print]

PMID:
31603987
3.

Long-Term Dabigatran Treatment Delays Alzheimer's Disease Pathogenesis in the TgCRND8 Mouse Model.

Cortes-Canteli M, Kruyer A, Fernandez-Nueda I, Marcos-Diaz A, Ceron C, Richards AT, Jno-Charles OC, Rodriguez I, Callejas S, Norris EH, Sanchez-Gonzalez J, Ruiz-Cabello J, Ibanez B, Strickland S, Fuster V.

J Am Coll Cardiol. 2019 Oct 15;74(15):1910-1923. doi: 10.1016/j.jacc.2019.07.081.

4.

Regulation of Mother-to-Offspring Transmission of mtDNA Heteroplasmy.

Latorre-Pellicer A, Lechuga-Vieco AV, Johnston IG, Hämäläinen RH, Pellico J, Justo-Méndez R, Fernández-Toro JM, Clavería C, Guaras A, Sierra R, Llop J, Torres M, Criado LM, Suomalainen A, Jones NS, Ruíz-Cabello J, Enríquez JA.

Cell Metab. 2019 Oct 3. pii: S1550-4131(19)30510-8. doi: 10.1016/j.cmet.2019.09.007. [Epub ahead of print]

5.

Cu-Doped Extremely Small Iron Oxide Nanoparticles with Large Longitudinal Relaxivity: One-Pot Synthesis and in Vivo Targeted Molecular Imaging.

Fernández-Barahona I, Gutiérrez L, Veintemillas-Verdaguer S, Pellico J, Morales MDP, Catala M, Del Pozo MA, Ruiz-Cabello J, Herranz F.

ACS Omega. 2019 Feb 6;4(2):2719-2727. doi: 10.1021/acsomega.8b03004. eCollection 2019 Feb 28.

6.

Metabolomic profile of acute respiratory distress syndrome of different etiologies.

Izquierdo-García JL, Nin N, Cardinal-Fernandez P, Ruiz-Cabello J, Lorente JÁ.

Intensive Care Med. 2019 Sep;45(9):1318-1320. doi: 10.1007/s00134-019-05634-w. Epub 2019 May 13. No abstract available.

PMID:
31087114
7.

p38γ is essential for cell cycle progression and liver tumorigenesis.

Tomás-Loba A, Manieri E, González-Terán B, Mora A, Leiva-Vega L, Santamans AM, Romero-Becerra R, Rodríguez E, Pintor-Chocano A, Feixas F, López JA, Caballero B, Trakala M, Blanco Ó, Torres JL, Hernández-Cosido L, Montalvo-Romeral V, Matesanz N, Roche-Molina M, Bernal JA, Mischo H, León M, Caballero A, Miranda-Saavedra D, Ruiz-Cabello J, Nevzorova YA, Cubero FJ, Bravo J, Vázquez J, Malumbres M, Marcos M, Osuna S, Sabio G.

Nature. 2019 Apr;568(7753):557-560. doi: 10.1038/s41586-019-1112-8. Epub 2019 Apr 10.

PMID:
30971822
8.

Quantitative assessment of myocardial blood flow and extracellular volume fraction using 68Ga-DOTA-PET: A feasibility and validation study in large animals.

Velasco C, Mota-Cobián A, Mota RA, Pellico J, Herranz F, Galán-Arriola C, Ibáñez B, Ruiz-Cabello J, Mateo J, España S.

J Nucl Cardiol. 2019 Mar 29. doi: 10.1007/s12350-019-01694-z. [Epub ahead of print]

PMID:
30927149
9.

Vascular smooth muscle cell-specific progerin expression in a mouse model of Hutchinson-Gilford progeria syndrome promotes arterial stiffness: Therapeutic effect of dietary nitrite.

Del Campo L, Sánchez-López A, Salaices M, von Kleeck RA, Expósito E, González-Gómez C, Cussó L, Guzmán-Martínez G, Ruiz-Cabello J, Desco M, Assoian RK, Briones AM, Andrés V.

Aging Cell. 2019 Jun;18(3):e12936. doi: 10.1111/acel.12936. Epub 2019 Mar 18.

10.

A dual 1H/19F birdcage coil for small animals at 7 T MRI.

Villa-Valverde P, Rodríguez I, Padró D, Benito M, Garrido-Salmon CE, Ruiz-Cabello J.

MAGMA. 2019 Feb;32(1):79-87. doi: 10.1007/s10334-018-00733-z. Epub 2019 Feb 16.

PMID:
30778714
11.

Unambiguous detection of atherosclerosis using bioorthogonal nanomaterials.

Pellico J, Fernández-Barahona I, Benito M, Gaitán-Simón Á, Gutiérrez L, Ruiz-Cabello J, Herranz F.

Nanomedicine. 2019 Apr;17:26-35. doi: 10.1016/j.nano.2018.12.015. Epub 2019 Jan 14.

PMID:
30654185
12.

MRI Study of the Influence of Surface Coating Aging on the In Vivo Biodistribution of Iron Oxide Nanoparticles.

Carregal-Romero S, Plaza-García S, Piñol R, Murillo JL, Ruiz-Cabello J, Padro D, Millán A, Ramos-Cabrer P.

Biosensors (Basel). 2018 Dec 12;8(4). pii: E127. doi: 10.3390/bios8040127.

13.

Aging and the Inflammasomes.

Marín-Aguilar F, Ruiz-Cabello J, Cordero MD.

Exp Suppl. 2018;108:303-320. doi: 10.1007/978-3-319-89390-7_13.

PMID:
30536177
14.

Synthesis of 68Ga Core-doped Iron Oxide Nanoparticles for Dual Positron Emission Tomography /(T1)Magnetic Resonance Imaging.

Fernández-Barahona I, Ruiz-Cabello J, Herranz F, Pellico J.

J Vis Exp. 2018 Nov 20;(141). doi: 10.3791/58269.

PMID:
30531725
15.

Identification of novel metabolomic biomarkers in an experimental model of septic acute kidney injury.

Izquierdo-Garcia JL, Nin N, Cardinal-Fernandez P, Rojas Y, de Paula M, Granados R, Martínez-Caro L, Ruíz-Cabello J, Lorente JA.

Am J Physiol Renal Physiol. 2019 Jan 1;316(1):F54-F62. doi: 10.1152/ajprenal.00315.2018. Epub 2018 Oct 31.

PMID:
30379100
16.

Metabolic Reprogramming in the Heart and Lung in a Murine Model of Pulmonary Arterial Hypertension.

Izquierdo-Garcia JL, Arias T, Rojas Y, Garcia-Ruiz V, Santos A, Martin-Puig S, Ruiz-Cabello J.

Front Cardiovasc Med. 2018 Aug 15;5:110. doi: 10.3389/fcvm.2018.00110. eCollection 2018.

17.

Hybrid Decorated Core@Shell Janus Nanoparticles as a Flexible Platform for Targeted Multimodal Molecular Bioimaging of Cancer.

Sánchez A, Ovejero Paredes K, Ruiz-Cabello J, Martínez-Ruíz P, Pingarrón JM, Villalonga R, Filice M.

ACS Appl Mater Interfaces. 2018 Sep 19;10(37):31032-31043. doi: 10.1021/acsami.8b10452. Epub 2018 Sep 7.

PMID:
30141615
18.

HIV transgene expression impairs K+ channel function in the pulmonary vasculature.

Mondejar-Parreño G, Morales-Cano D, Barreira B, Callejo M, Ruiz-Cabello J, Moreno L, Esquivel-Ruiz S, Mathie A, Butrous G, Perez-Vizcaino F, Cogolludo A.

Am J Physiol Lung Cell Mol Physiol. 2018 Nov 1;315(5):L711-L723. doi: 10.1152/ajplung.00045.2018. Epub 2018 Aug 23.

19.

Micellar Iron Oxide Nanoparticles Coated with Anti-Tumor Glycosides.

Groult H, García-Álvarez I, Romero-Ramírez L, Nieto-Sampedro M, Herranz F, Fernández-Mayoralas A, Ruiz-Cabello J.

Nanomaterials (Basel). 2018 Jul 25;8(8). pii: E567. doi: 10.3390/nano8080567.

20.

Ablation of the stress protease OMA1 protects against heart failure in mice.

Acin-Perez R, Lechuga-Vieco AV, Del Mar Muñoz M, Nieto-Arellano R, Torroja C, Sánchez-Cabo F, Jiménez C, González-Guerra A, Carrascoso I, Benincá C, Quiros PM, López-Otín C, Castellano JM, Ruíz-Cabello J, Jiménez-Borreguero LJ, Enríquez JA.

Sci Transl Med. 2018 Mar 28;10(434). pii: eaan4935. doi: 10.1126/scitranslmed.aan4935.

PMID:
29593106
21.

Iron Oxide Nanoradiomaterials: Combining Nanoscale Properties with Radioisotopes for Enhanced Molecular Imaging.

Pellico J, Llop J, Fernández-Barahona I, Bhavesh R, Ruiz-Cabello J, Herranz F.

Contrast Media Mol Imaging. 2017 Nov 21;2017:1549580. doi: 10.1155/2017/1549580. eCollection 2017. Review.

22.

Protein corona and phospholipase activity drive selective accumulation of nanomicelles in atherosclerotic plaques.

Lechuga-Vieco AV, Groult H, Pellico J, Mateo J, Enríquez JA, Ruiz-Cabello J, Herranz F.

Nanomedicine. 2018 Apr;14(3):643-650. doi: 10.1016/j.nano.2017.12.021. Epub 2018 Jan 6.

PMID:
29317346
23.

Metabolomic Profile of ARDS by Nuclear Magnetic Resonance Spectroscopy in Patients With H1N1 Influenza Virus Pneumonia.

Izquierdo-Garcia JL, Nin N, Jimenez-Clemente J, Horcajada JP, Arenas-Miras MDM, Gea J, Esteban A, Ruiz-Cabello J, Lorente JA.

Shock. 2018 Nov;50(5):504-510. doi: 10.1097/SHK.0000000000001099.

PMID:
29293175
24.

NLRP3-inflammasome inhibition prevents high fat and high sugar diets-induced heart damage through autophagy induction.

Pavillard LE, Cañadas-Lozano D, Alcocer-Gómez E, Marín-Aguilar F, Pereira S, Robertson AAB, Muntané J, Ryffel B, Cooper MA, Quiles JL, Bullón P, Ruiz-Cabello J, Cordero MD.

Oncotarget. 2017 Sep 8;8(59):99740-99756. doi: 10.18632/oncotarget.20763. eCollection 2017 Nov 21.

25.

In vivo imaging of lung inflammation with neutrophil-specific 68Ga nano-radiotracer.

Pellico J, Lechuga-Vieco AV, Almarza E, Hidalgo A, Mesa-Nuñez C, Fernández-Barahona I, Quintana JA, Bueren J, Enríquez JA, Ruiz-Cabello J, Herranz F.

Sci Rep. 2017 Oct 16;7(1):13242. doi: 10.1038/s41598-017-12829-y.

26.

MKK6 controls T3-mediated browning of white adipose tissue.

Matesanz N, Bernardo E, Acín-Pérez R, Manieri E, Pérez-Sieira S, Hernández-Cosido L, Montalvo-Romeral V, Mora A, Rodríguez E, Leiva-Vega L, Lechuga-Vieco AV, Ruiz-Cabello J, Torres JL, Crespo-Ruiz M, Centeno F, Álvarez CV, Marcos M, Enríquez JA, Nogueiras R, Sabio G.

Nat Commun. 2017 Oct 11;8(1):856. doi: 10.1038/s41467-017-00948-z.

27.

One-Step Fast Synthesis of Nanoparticles for MRI: Coating Chemistry as the Key Variable Determining Positive or Negative Contrast.

Pellico J, Ruiz-Cabello J, Fernández-Barahona I, Gutiérrez L, Lechuga-Vieco AV, Enríquez JA, Morales MP, Herranz F.

Langmuir. 2017 Oct 3;33(39):10239-10247. doi: 10.1021/acs.langmuir.7b01759. Epub 2017 Sep 18.

PMID:
28882034
28.

Family of Bioactive Heparin-Coated Iron Oxide Nanoparticles with Positive Contrast in Magnetic Resonance Imaging for Specific Biomedical Applications.

Groult H, Poupard N, Herranz F, Conforto E, Bridiau N, Sannier F, Bordenave S, Piot JM, Ruiz-Cabello J, Fruitier-Arnaudin I, Maugard T.

Biomacromolecules. 2017 Oct 9;18(10):3156-3167. doi: 10.1021/acs.biomac.7b00797. Epub 2017 Sep 22.

PMID:
28850787
29.

Experimental methods for flow and aerosol measurements in human airways and their replicas.

Lizal F, Jedelsky J, Morgan K, Bauer K, Llop J, Cossio U, Kassinos S, Verbanck S, Ruiz-Cabello J, Santos A, Koch E, Schnabel C.

Eur J Pharm Sci. 2018 Feb 15;113:95-131. doi: 10.1016/j.ejps.2017.08.021. Epub 2017 Aug 23. Review.

PMID:
28842353
30.

The effect of tissue-segmented attenuation maps on PET quantification with a special focus on large arteries.

Mota-Cobian A, Alonso-Farto JC, Fernández-Friera L, Sánchez-González J, López-Melgar B, Jiménez-Borreguero LJ, Fuster V, Ruiz-Cabello J, España S.

Rev Esp Med Nucl Imagen Mol. 2018 Mar - Apr;37(2):94-102. doi: 10.1016/j.remn.2017.03.008. Epub 2017 Jun 20. English, Spanish.

PMID:
28641952
31.

Retraction: Bmi1 limits dilated cardiomyopathy and heart failure by inhibiting cardiac senescence.

Gonzalez-Valdes I, Hidalgo I, Bujarrabal A, Lara-Pezzi E, Padron-Barthe L, Garcia-Pavia P, Gómez-Del Arco P, Redondo JM, Ruiz-Cabello JM, Jimenez-Borreguero LJ, Enriquez JA, de la Pompa JL, Hidalgo A, Gonzalez S.

Nat Commun. 2017 Mar 7;8:14006. doi: 10.1038/ncomms14006. No abstract available.

32.

Assessment of regional pulmonary blood flow using 68Ga-DOTA PET.

Velasco C, Mateo J, Santos A, Mota-Cobian A, Herranz F, Pellico J, Mota RA, España S, Ruiz-Cabello J.

EJNMMI Res. 2017 Dec;7(1):7. doi: 10.1186/s13550-017-0259-2. Epub 2017 Jan 18.

33.

Effects of Quercetin in a Rat Model of Hemorrhagic Traumatic Shock and Reperfusion.

Chamorro V, Pandolfi R, Moreno L, Barreira B, Martínez-Ramas A, Morales-Cano D, Ruiz-Cabello J, Lorente JA, Duarte J, Cogolludo Á, Alvarez-Sala JL, Perez-Vizcaino F.

Molecules. 2016 Dec 20;21(12). pii: E1739. doi: 10.3390/molecules21121739.

34.

Myocardial VHL-HIF Signaling Controls an Embryonic Metabolic Switch Essential for Cardiac Maturation.

Menendez-Montes I, Escobar B, Palacios B, Gómez MJ, Izquierdo-Garcia JL, Flores L, Jiménez-Borreguero LJ, Aragones J, Ruiz-Cabello J, Torres M, Martin-Puig S.

Dev Cell. 2016 Dec 19;39(6):724-739. doi: 10.1016/j.devcel.2016.11.012.

35.

Could NLRP3-Inflammasome Be a Cardiovascular Risk Biomarker in Acute Myocardial Infarction Patients?

Bullón P, Cano-García FJ, Alcocer-Gómez E, Varela-López A, Roman-Malo L, Ruiz-Salmerón RJ, Quiles JL, Navarro-Pando JM, Battino M, Ruiz-Cabello J, Jiménez-Borreguero LJ, Cordero MD.

Antioxid Redox Signal. 2017 Aug 10;27(5):269-275. doi: 10.1089/ars.2016.6970. Epub 2017 Jan 20.

PMID:
27967213
36.

Corrigendum: Mitochondrial and nuclear DNA matching shapes metabolism and healthy ageing.

Latorre-Pellicer A, Moreno-Loshuertos R, Lechuga-Vieco AV, Sánchez-Cabo F, Torroja C, Acín-Pérez R, Calvo E, Aix E, González-Guerra A, Logan A, Bernad-Miana ML, Romanos E, Cruz R, Cogliati S, Sobrino B, Carracedo Á, Pérez-Martos A, Fernández-Silva P, Ruíz-Cabello J, Murphy MP, Flores I, Vázquez J, Enríquez JA.

Nature. 2017 Feb 2;542(7639):124. doi: 10.1038/nature20773. Epub 2016 Dec 7. No abstract available.

PMID:
27926738
37.

Recent advances in the preparation and application of multifunctional iron oxide and liposome-based nanosystems for multimodal diagnosis and therapy.

Marciello M, Pellico J, Fernandez-Barahona I, Herranz F, Ruiz-Cabello J, Filice M.

Interface Focus. 2016 Dec 6;6(6):20160055. Review.

38.

Non-Invasive Imaging of Lung Remodeling and Right Ventricle Metabolic Shift in an Animal Model of Pulmonary Hypertension.

Arias T, Mateo J, España S, Izquierdo JL, Jiménez-Borreguero JJ, Ruiz-Cabello JM.

J Am Soc Hypertens. 2016 Jul;10 Suppl 1:e1-e2. doi: 10.1016/j.jash.2016.06.006. No abstract available.

PMID:
27677127
39.

New Biochemical Insights into the Mechanisms of Pulmonary Arterial Hypertension in Humans.

Bujak R, Mateo J, Blanco I, Izquierdo-García JL, Dudzik D, Markuszewski MJ, Peinado VI, Laclaustra M, Barberá JA, Barbas C, Ruiz-Cabello J.

PLoS One. 2016 Aug 3;11(8):e0160505. doi: 10.1371/journal.pone.0160505. eCollection 2016.

40.

Mitochondrial and nuclear DNA matching shapes metabolism and healthy ageing.

Latorre-Pellicer A, Moreno-Loshuertos R, Lechuga-Vieco AV, Sánchez-Cabo F, Torroja C, Acín-Pérez R, Calvo E, Aix E, González-Guerra A, Logan A, Bernad-Miana ML, Romanos E, Cruz R, Cogliati S, Sobrino B, Carracedo Á, Pérez-Martos A, Fernández-Silva P, Ruíz-Cabello J, Murphy MP, Flores I, Vázquez J, Enríquez JA.

Nature. 2016 Jul 28;535(7613):561-5. Epub 2016 Jul 6.

PMID:
27383793
41.

Accurate quantification of atherosclerotic plaque volume by 3D vascular ultrasound using the volumetric linear array method.

López-Melgar B, Fernández-Friera L, Sánchez-González J, Vilchez JP, Cecconi A, Mateo J, Peñalvo JL, Oliva B, García-Ruiz JM, Kauffman S, Jiménez-Borreguero LJ, Ruiz-Cabello J, Fernández-Ortiz A, Ibáñez B, Fuster V.

Atherosclerosis. 2016 May;248:230-7. doi: 10.1016/j.atherosclerosis.2016.03.002. Epub 2016 Mar 15.

PMID:
27038420
42.

Microwave-driven Synthesis of Iron Oxide Nanoparticles for Fast Detection of Atherosclerosis.

Pellico J, Ruiz-Cabello J, Herranz F.

J Vis Exp. 2016 Mar 22;(109). doi: 10.3791/53472.

43.

Lung Tissue Volume is Elevated in Obesity and Reduced by Bariatric Surgery.

Santos A, Rivas E, Rodríguez-Roisin R, Sánchez M, Ruiz-Cabello J, Arismendi E, Venegas JG.

Obes Surg. 2016 Oct;26(10):2475-82. doi: 10.1007/s11695-016-2137-9.

PMID:
27000884
44.

Fast synthesis and bioconjugation of (68) Ga core-doped extremely small iron oxide nanoparticles for PET/MR imaging.

Pellico J, Ruiz-Cabello J, Saiz-Alía M, Del Rosario G, Caja S, Montoya M, Fernández de Manuel L, Morales MP, Gutiérrez L, Galiana B, Enríquez JA, Herranz F.

Contrast Media Mol Imaging. 2016 May;11(3):203-10. doi: 10.1002/cmmi.1681. Epub 2016 Jan 8.

PMID:
26748837
45.

Cardiovascular imaging: what have we learned from animal models?

Santos A, Fernández-Friera L, Villalba M, López-Melgar B, España S, Mateo J, Mota RA, Jiménez-Borreguero J, Ruiz-Cabello J.

Front Pharmacol. 2015 Oct 21;6:227. doi: 10.3389/fphar.2015.00227. eCollection 2015. Review.

46.

T₁-MRI Fluorescent Iron Oxide Nanoparticles by Microwave Assisted Synthesis.

Bhavesh R, Lechuga-Vieco AV, Ruiz-Cabello J, Herranz F.

Nanomaterials (Basel). 2015 Nov 4;5(4):1880-1890. doi: 10.3390/nano5041880.

47.

Magnetic Resonance Imaging of the Atherosclerotic Mouse Aorta.

Mateo J, Benito M, España S, Sanz J, Jiménez-Borreguero J, Fuster V, Ruiz-Cabello J.

Methods Mol Biol. 2015;1339:387-94. doi: 10.1007/978-1-4939-2929-0_29.

PMID:
26445806
48.

In Vivo ¹⁸F-FDG-PET Imaging in Mouse Atherosclerosis.

Mateo J, Bilbao I, Vaquero JJ, Ruiz-Cabello J, España S.

Methods Mol Biol. 2015;1339:377-86. doi: 10.1007/978-1-4939-2929-0_28.

PMID:
26445805
49.

Stress-Induced Depressive Behaviors Require a Functional NLRP3 Inflammasome.

Alcocer-Gómez E, Ulecia-Morón C, Marín-Aguilar F, Rybkina T, Casas-Barquero N, Ruiz-Cabello J, Ryffel B, Apetoh L, Ghiringhelli F, Bullón P, Sánchez-Alcazar JA, Carrión AM, Cordero MD.

Mol Neurobiol. 2016 Sep;53(7):4874-82. doi: 10.1007/s12035-015-9408-7. Epub 2015 Sep 11.

PMID:
26362308
50.

AMPK Phosphorylation Modulates Pain by Activation of NLRP3 Inflammasome.

Bullón P, Alcocer-Gómez E, Carrión AM, Marín-Aguilar F, Garrido-Maraver J, Román-Malo L, Ruiz-Cabello J, Culic O, Ryffel B, Apetoh L, Ghiringhelli F, Battino M, Sánchez-Alcazar JA, Cordero MD.

Antioxid Redox Signal. 2016 Jan 20;24(3):157-70. doi: 10.1089/ars.2014.6120. Epub 2015 Sep 16.

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