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Items: 14

1.

Phenotype-Based Screens with Conformation-Specific Inhibitors Reveal p38 Gamma and Delta as Targets for HCC Polypharmacology.

Yu JX, Craig AJ, Duffy ME, Villacorta-Martin C, Miguela V, Ruiz de Galarreta M, Scopton AP, Silber L, Maldonado AY, Rialdi A, Guccione E, Lujambio A, Villanueva A, Dar AC.

Mol Cancer Ther. 2019 Sep;18(9):1506-1519. doi: 10.1158/1535-7163.MCT-18-0571. Epub 2019 Jun 18.

PMID:
31213506
2.

β-Catenin Activation Promotes Immune Escape and Resistance to Anti-PD-1 Therapy in Hepatocellular Carcinoma.

Ruiz de Galarreta M, Bresnahan E, Molina-Sánchez P, Lindblad KE, Maier B, Sia D, Puigvehi M, Miguela V, Casanova-Acebes M, Dhainaut M, Villacorta-Martin C, Singhi AD, Moghe A, von Felden J, Tal Grinspan L, Wang S, Kamphorst AO, Monga SP, Brown BD, Villanueva A, Llovet JM, Merad M, Lujambio A.

Cancer Discov. 2019 Aug;9(8):1124-1141. doi: 10.1158/2159-8290.CD-19-0074. Epub 2019 Jun 11.

PMID:
31186238
3.

Hepatocellular carcinoma: killing one bird with two stones.

Ruiz de Galarreta M, Lujambio A.

Gut. 2019 Sep;68(9):1543-1544. doi: 10.1136/gutjnl-2019-318649. Epub 2019 May 10. No abstract available.

PMID:
31076399
4.

Erratum: DNA sensing in senescence.

Ruiz de Galarreta M, Lujambio A.

Nat Cell Biol. 2017 Nov 29;19(12):1441. doi: 10.1038/ncb3644.

PMID:
29184173
5.

Cell type-specific pharmacological kinase inhibition for cancer chemoprevention.

Deshmukh M, Nakagawa S, Higashi T, Vincek A, Venkatesh A, Ruiz de Galarreta M, Koh AP, Goossens N, Hirschfield H, Bian CB, Fujiwara N, Ono A, Hoshida H, El-Abtah M, Ahmad NB, Lujambio A, Sanchez R, Fuchs BC, Poelstra K, Prakash J, Hoshida Y; Precision Liver Cancer Prevention Consortium.

Nanomedicine. 2018 Feb;14(2):317-325. doi: 10.1016/j.nano.2017.11.004. Epub 2017 Nov 20.

6.

Freeze-dried strawberry and blueberry attenuates diet-induced obesity and insulin resistance in rats by inhibiting adipogenesis and lipogenesis.

Aranaz P, Romo-Hualde A, Zabala M, Navarro-Herrera D, Ruiz de Galarreta M, Gil AG, Martinez JA, Milagro FI, González-Navarro CJ.

Food Funct. 2017 Nov 15;8(11):3999-4013. doi: 10.1039/c7fo00996h.

PMID:
29022978
7.

DNA sensing in senescence.

Ruiz de Galarreta M, Lujambio A.

Nat Cell Biol. 2017 Aug 31;19(9):1008-1009. doi: 10.1038/ncb3603. Erratum in: Nat Cell Biol. 2017 Nov 29;19(12 ):1441.

PMID:
28855731
8.

Therapeutic editing of hepatocyte genome in vivo.

Ruiz de Galarreta M, Lujambio A.

J Hepatol. 2017 Oct;67(4):818-828. doi: 10.1016/j.jhep.2017.05.012. Epub 2017 May 17. Review.

PMID:
28527665
9.

Palbociclib (PD-0332991), a selective CDK4/6 inhibitor, restricts tumour growth in preclinical models of hepatocellular carcinoma.

Bollard J, Miguela V, Ruiz de Galarreta M, Venkatesh A, Bian CB, Roberto MP, Tovar V, Sia D, Molina-Sánchez P, Nguyen CB, Nakagawa S, Llovet JM, Hoshida Y, Lujambio A.

Gut. 2017 Jul;66(7):1286-1296. doi: 10.1136/gutjnl-2016-312268. Epub 2016 Nov 14.

10.

Cartilage oligomeric matrix protein participates in the pathogenesis of liver fibrosis.

Magdaleno F, Arriazu E, Ruiz de Galarreta M, Chen Y, Ge X, Conde de la Rosa L, Nieto N.

J Hepatol. 2016 Nov;65(5):963-971. doi: 10.1016/j.jhep.2016.06.003. Epub 2016 Jun 15.

11.

Oxidation pathways underlying the pro-oxidant effects of apigenin.

Andueza A, García-Garzón A, Ruiz de Galarreta M, Ansorena E, Iraburu MJ, López-Zabalza MJ, Martínez-Irujo JJ.

Free Radic Biol Med. 2015 Oct;87:169-80. doi: 10.1016/j.freeradbiomed.2015.06.003. Epub 2015 Jun 25.

PMID:
26119779
12.

Fibronectin peptides as potential regulators of hepatic fibrosis through apoptosis of hepatic stellate cells.

Mòdol T, Brice N, Ruiz de Galarreta M, García Garzón A, Iraburu MJ, Martínez-Irujo JJ, López-Zabalza MJ.

J Cell Physiol. 2015 Mar;230(3):546-53. doi: 10.1002/jcp.24714.

PMID:
24976518
13.

Extracellular matrix and liver disease.

Arriazu E, Ruiz de Galarreta M, Cubero FJ, Varela-Rey M, Pérez de Obanos MP, Leung TM, Lopategi A, Benedicto A, Abraham-Enachescu I, Nieto N.

Antioxid Redox Signal. 2014 Sep 1;21(7):1078-97. doi: 10.1089/ars.2013.5697. Epub 2014 Jan 8. Review.

14.

GCN2 kinase is a key regulator of fibrogenesis and acute and chronic liver injury induced by carbon tetrachloride in mice.

Arriazu E, Ruiz de Galarreta M, López-Zabalza MJ, Leung TM, Nieto N, Iraburu MJ.

Lab Invest. 2013 Mar;93(3):303-10. doi: 10.1038/labinvest.2012.173. Epub 2013 Jan 14.

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