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Items: 42

1.

Splenectomy reduces lung metastases and tumoral and metastatic niche inflammation.

Stöth M, Freire Valls A, Chen M, Hidding S, Knipper K, Shen Y, Klose J, Ulrich A, Ruiz de Almodovar C, Schneider M, Schmidt T.

Int J Cancer. 2019 Apr 29. doi: 10.1002/ijc.32378. [Epub ahead of print]

PMID:
31034094
2.

Blood Vessels as Regulators of Neural Stem Cell Properties.

Karakatsani A, Shah B, Ruiz de Almodovar C.

Front Mol Neurosci. 2019 Apr 12;12:85. doi: 10.3389/fnmol.2019.00085. eCollection 2019. Review.

3.

Role of retinal pigment epithelium-derived exosomes and autophagy in new blood vessel formation.

Atienzar-Aroca S, Serrano-Heras G, Freire Valls A, Ruiz de Almodovar C, Muriach M, Barcia JM, Garcia-Verdugo JM, Romero FJ, Sancho-Pelluz J.

J Cell Mol Med. 2018 Nov;22(11):5244-5256. doi: 10.1111/jcmm.13730. Epub 2018 Aug 21.

4.

Unconventional Secretion Mediates the Trans-cellular Spreading of Tau.

Katsinelos T, Zeitler M, Dimou E, Karakatsani A, Müller HM, Nachman E, Steringer JP, Ruiz de Almodovar C, Nickel W, Jahn TR.

Cell Rep. 2018 May 15;23(7):2039-2055. doi: 10.1016/j.celrep.2018.04.056.

5.

Neurovascular Communication during CNS Development.

Paredes I, Himmels P, Ruiz de Almodóvar C.

Dev Cell. 2018 Apr 9;45(1):10-32. doi: 10.1016/j.devcel.2018.01.023. Review.

6.

A PRDX1-p38α heterodimer amplifies MET-driven invasion of IDH-wildtype and IDH-mutant gliomas.

Wirthschaft P, Bode J, Simon AEM, Hoffmann E, van Laack R, Krüwel T, Dietrich F, Bucher D, Hahn A, Sahm F, Breckwoldt MO, Kurz FT, Hielscher T, Fischer B, Dross N, Ruiz de Almodovar C, von Deimling A, Herold-Mende C, Plass C, Boulant S, Wiestler B, Reifenberger G, Lichter P, Wick W, Tews B.

Int J Cancer. 2018 Sep 1;143(5):1176-1187. doi: 10.1002/ijc.31404. Epub 2018 Apr 16.

PMID:
29582423
7.

Neuronal LRP4 regulates synapse formation in the developing CNS.

Karakatsani A, Marichal N, Urban S, Kalamakis G, Ghanem A, Schick A, Zhang Y, Conzelmann KK, Rüegg MA, Berninger B, Ruiz de Almodovar C, Gascón S, Kröger S.

Development. 2017 Dec 15;144(24):4604-4615. doi: 10.1242/dev.150110. Epub 2017 Oct 23.

8.

YAP/TAZ Orchestrate VEGF Signaling during Developmental Angiogenesis.

Wang X, Freire Valls A, Schermann G, Shen Y, Moya IM, Castro L, Urban S, Solecki GM, Winkler F, Riedemann L, Jain RK, Mazzone M, Schmidt T, Fischer T, Halder G, Ruiz de Almodóvar C.

Dev Cell. 2017 Sep 11;42(5):462-478.e7. doi: 10.1016/j.devcel.2017.08.002. Epub 2017 Aug 31.

9.

CNS Macrophages Control Neurovascular Development via CD95L.

Chen S, Tisch N, Kegel M, Yerbes R, Hermann R, Hudalla H, Zuliani C, Gülcüler GS, Zwadlo K, von Engelhardt J, Ruiz de Almodóvar C, Martin-Villalba A.

Cell Rep. 2017 May 16;19(7):1378-1393. doi: 10.1016/j.celrep.2017.04.056.

10.

Motor neurons control blood vessel patterning in the developing spinal cord.

Himmels P, Paredes I, Adler H, Karakatsani A, Luck R, Marti HH, Ermakova O, Rempel E, Stoeckli ET, Ruiz de Almodóvar C.

Nat Commun. 2017 Mar 6;8:14583. doi: 10.1038/ncomms14583.

11.

TAM receptors Tyro3 and Mer as novel targets in colorectal cancer.

Schmitz R, Valls AF, Yerbes R, von Richter S, Kahlert C, Loges S, Weitz J, Schneider M, Ruiz de Almodovar C, Ulrich A, Schmidt T.

Oncotarget. 2016 Aug 30;7(35):56355-56370. doi: 10.18632/oncotarget.10889.

12.

The Oxygen Sensor PHD2 Controls Dendritic Spines and Synapses via Modification of Filamin A.

Segura I, Lange C, Knevels E, Moskalyuk A, Pulizzi R, Eelen G, Chaze T, Tudor C, Boulegue C, Holt M, Daelemans D, Matondo M, Ghesquière B, Giugliano M, Ruiz de Almodovar C, Dewerchin M, Carmeliet P.

Cell Rep. 2016 Mar 22;14(11):2653-67. doi: 10.1016/j.celrep.2016.02.047. Epub 2016 Mar 10.

13.

Human mesenchymal stem cells enhance the systemic effects of radiotherapy.

de Araújo Farias V, O'Valle F, Lerma BA, Ruiz de Almodóvar C, López-Peñalver JJ, Nieto A, Santos A, Fernández BI, Guerra-Librero A, Ruiz-Ruiz MC, Guirado D, Schmidt T, Oliver FJ, Ruiz de Almodóvar JM.

Oncotarget. 2015 Oct 13;6(31):31164-80. doi: 10.18632/oncotarget.5216.

14.

The Orphan Receptor Tie1 Controls Angiogenesis and Vascular Remodeling by Differentially Regulating Tie2 in Tip and Stalk Cells.

Savant S, La Porta S, Budnik A, Busch K, Hu J, Tisch N, Korn C, Valls AF, Benest AV, Terhardt D, Qu X, Adams RH, Baldwin HS, Ruiz de Almodóvar C, Rodewald HR, Augustin HG.

Cell Rep. 2015 Sep 22;12(11):1761-73. doi: 10.1016/j.celrep.2015.08.024. Epub 2015 Sep 3.

15.

Inhibition of Ebola virus glycoprotein-mediated cytotoxicity by targeting its transmembrane domain and cholesterol.

Hacke M, Björkholm P, Hellwig A, Himmels P, Ruiz de Almodóvar C, Brügger B, Wieland F, Ernst AM.

Nat Commun. 2015 Jul 9;6:7688. doi: 10.1038/ncomms8688.

PMID:
26158910
16.

Glioma cell VEGFR-2 confers resistance to chemotherapeutic and antiangiogenic treatments in PTEN-deficient glioblastoma.

Kessler T, Sahm F, Blaes J, Osswald M, Rübmann P, Milford D, Urban S, Jestaedt L, Heiland S, Bendszus M, Hertenstein A, Pfenning PN, Ruiz de Almodóvar C, Wick A, Winkler F, von Deimling A, Platten M, Wick W, Weiler M.

Oncotarget. 2015 Oct 13;6(31):31050-68. doi: 10.18632/oncotarget.2910.

17.

Neurodegeneration, neurogenesis, and oxidative stress.

Santos R, Ruiz de Almodóvar C, Bulteau AL, Gomes CM.

Oxid Med Cell Longev. 2013;2013:730581. doi: 10.1155/2013/730581. Epub 2013 Nov 24. No abstract available.

18.

The NADPH oxidase Nox2 regulates VEGFR1/CSF-1R-mediated microglial chemotaxis and promotes early postnatal infiltration of phagocytes in the subventricular zone of the mouse cerebral cortex.

Lelli A, Gervais A, Colin C, Chéret C, Ruiz de Almodovar C, Carmeliet P, Krause KH, Boillée S, Mallat M.

Glia. 2013 Sep;61(9):1542-55. doi: 10.1002/glia.22540. Epub 2013 Jul 8.

PMID:
23836548
19.

Inhibition of tumor angiogenesis and growth by a small-molecule multi-FGF receptor blocker with allosteric properties.

Bono F, De Smet F, Herbert C, De Bock K, Georgiadou M, Fons P, Tjwa M, Alcouffe C, Ny A, Bianciotto M, Jonckx B, Murakami M, Lanahan AA, Michielsen C, Sibrac D, Dol-Gleizes F, Mazzone M, Zacchigna S, Herault JP, Fischer C, Rigon P, Ruiz de Almodovar C, Claes F, Blanc I, Poesen K, Zhang J, Segura I, Gueguen G, Bordes MF, Lambrechts D, Broussy R, van de Wouwer M, Michaux C, Shimada T, Jean I, Blacher S, Noel A, Motte P, Rom E, Rakic JM, Katsuma S, Schaeffer P, Yayon A, Van Schepdael A, Schwalbe H, Gervasio FL, Carmeliet G, Rozensky J, Dewerchin M, Simons M, Christopoulos A, Herbert JM, Carmeliet P.

Cancer Cell. 2013 Apr 15;23(4):477-88. doi: 10.1016/j.ccr.2013.02.019.

20.

VEGF ligands and receptors: implications in neurodevelopment and neurodegeneration.

Carmeliet P, Ruiz de Almodovar C.

Cell Mol Life Sci. 2013 May;70(10):1763-78. doi: 10.1007/s00018-013-1283-7. Epub 2013 Mar 12. Review. Erratum in: Cell Mol Life Sci. 2013 Jun;70(12):2221. Carmen, Ruiz de Almodovar [corrected to Ruiz de Almodovar, Carmen].

PMID:
23475071
21.

Targeting placental growth factor/neuropilin 1 pathway inhibits growth and spread of medulloblastoma.

Snuderl M, Batista A, Kirkpatrick ND, Ruiz de Almodovar C, Riedemann L, Walsh EC, Anolik R, Huang Y, Martin JD, Kamoun W, Knevels E, Schmidt T, Farrar CT, Vakoc BJ, Mohan N, Chung E, Roberge S, Peterson T, Bais C, Zhelyazkova BH, Yip S, Hasselblatt M, Rossig C, Niemeyer E, Ferrara N, Klagsbrun M, Duda DG, Fukumura D, Xu L, Carmeliet P, Jain RK.

Cell. 2013 Feb 28;152(5):1065-76. doi: 10.1016/j.cell.2013.01.036.

22.

VEGF modulates NMDA receptors activity in cerebellar granule cells through Src-family kinases before synapse formation.

Meissirel C, Ruiz de Almodovar C, Knevels E, Coulon C, Chounlamountri N, Segura I, de Rossi P, Vinckier S, Anthonis K, Deléglise B, de Mol M, Ali C, Dassonville K, Loyens E, Honnorat J, Michotte Y, Rogemond V, Smolders I, Voets T, Vivien D, Vanden Berghe P, Van den Bosch L, Robberecht W, Chédotal A, Oliviero S, Dewerchin M, Schmucker D, Thomasset N, Salin P, Carmeliet P.

Proc Natl Acad Sci U S A. 2011 Aug 16;108(33):13782-7. doi: 10.1073/pnas.1100341108. Epub 2011 Jul 29.

23.

VEGF mediates commissural axon chemoattraction through its receptor Flk1.

Ruiz de Almodovar C, Fabre PJ, Knevels E, Coulon C, Segura I, Haddick PC, Aerts L, Delattin N, Strasser G, Oh WJ, Lange C, Vinckier S, Haigh J, Fouquet C, Gu C, Alitalo K, Castellani V, Tessier-Lavigne M, Chedotal A, Charron F, Carmeliet P.

Neuron. 2011 Jun 9;70(5):966-78. doi: 10.1016/j.neuron.2011.04.014.

24.

Matrix-binding vascular endothelial growth factor (VEGF) isoforms guide granule cell migration in the cerebellum via VEGF receptor Flk1.

Ruiz de Almodovar C, Coulon C, Salin PA, Knevels E, Chounlamountri N, Poesen K, Hermans K, Lambrechts D, Van Geyte K, Dhondt J, Dresselaers T, Renaud J, Aragones J, Zacchigna S, Geudens I, Gall D, Stroobants S, Mutin M, Dassonville K, Storkebaum E, Jordan BF, Eriksson U, Moons L, D'Hooge R, Haigh JJ, Belin MF, Schiffmann S, Van Hecke P, Gallez B, Vinckier S, Chédotal A, Honnorat J, Thomasset N, Carmeliet P, Meissirel C.

J Neurosci. 2010 Nov 10;30(45):15052-66. doi: 10.1523/JNEUROSCI.0477-10.2010.

25.

Epithelial: Endothelial cross-talk regulates exocrine differentiation in developing pancreas.

Pierreux CE, Cordi S, Hick AC, Achouri Y, Ruiz de Almodovar C, Prévot PP, Courtoy PJ, Carmeliet P, Lemaigre FP.

Dev Biol. 2010 Nov 1;347(1):216-27. doi: 10.1016/j.ydbio.2010.08.024. Epub 2010 Aug 31.

26.

Impaired autonomic regulation of resistance arteries in mice with low vascular endothelial growth factor or upon vascular endothelial growth factor trap delivery.

Storkebaum E, Ruiz de Almodovar C, Meens M, Zacchigna S, Mazzone M, Vanhoutte G, Vinckier S, Miskiewicz K, Poesen K, Lambrechts D, Janssen GM, Fazzi GE, Verstreken P, Haigh J, Schiffers PM, Rohrer H, Van der Linden A, De Mey JG, Carmeliet P.

Circulation. 2010 Jul 20;122(3):273-81. doi: 10.1161/CIRCULATIONAHA.109.929364. Epub 2010 Jul 6.

PMID:
20606119
27.

Role of delta-like-4/Notch in the formation and wiring of the lymphatic network in zebrafish.

Geudens I, Herpers R, Hermans K, Segura I, Ruiz de Almodovar C, Bussmann J, De Smet F, Vandevelde W, Hogan BM, Siekmann A, Claes F, Moore JC, Pistocchi AS, Loges S, Mazzone M, Mariggi G, Bruyère F, Cotelli F, Kerjaschki D, Noël A, Foidart JM, Gerhardt H, Ny A, Langenberg T, Lawson ND, Duckers HJ, Schulte-Merker S, Carmeliet P, Dewerchin M.

Arterioscler Thromb Vasc Biol. 2010 Sep;30(9):1695-702. doi: 10.1161/ATVBAHA.110.203034. Epub 2010 May 13.

28.

The neurovascular link in health and disease: an update.

Segura I, De Smet F, Hohensinner PJ, Ruiz de Almodovar C, Carmeliet P.

Trends Mol Med. 2009 Oct;15(10):439-51. doi: 10.1016/j.molmed.2009.08.005. Epub 2009 Oct 2. Review.

PMID:
19801203
29.

Role and therapeutic potential of VEGF in the nervous system.

Ruiz de Almodovar C, Lambrechts D, Mazzone M, Carmeliet P.

Physiol Rev. 2009 Apr;89(2):607-48. doi: 10.1152/physrev.00031.2008. Review.

30.

Building in resistance to endothelial cell death.

Mazzone M, Ruiz de Almodovar C, Carmeliet P.

Nat Genet. 2007 Nov;39(11):1308-9. No abstract available.

PMID:
17968346
31.

Similarities between angiogenesis and neural development: what small animal models can tell us.

Zacchigna S, Ruiz de Almodovar C, Carmeliet P.

Curr Top Dev Biol. 2008;80:1-55. Review.

PMID:
17950371
32.

A new mouse model to study acquired lymphedema.

Schneider M, Ny A, Ruiz de Almodovar C, Carmeliet P.

PLoS Med. 2006 Jul;3(7):e264. Epub 2006 Jul 18. No abstract available.

33.

Selective regulation of arterial branching morphogenesis by synectin.

Chittenden TW, Claes F, Lanahan AA, Autiero M, Palac RT, Tkachenko EV, Elfenbein A, Ruiz de Almodovar C, Dedkov E, Tomanek R, Li W, Westmore M, Singh JP, Horowitz A, Mulligan-Kehoe MJ, Moodie KL, Zhuang ZW, Carmeliet P, Simons M.

Dev Cell. 2006 Jun;10(6):783-95.

34.

An SDF-1 trap for myeloid cells stimulates angiogenesis.

Ruiz de Almodovar C, Luttun A, Carmeliet P.

Cell. 2006 Jan 13;124(1):18-21. Review.

35.

Interferon-gamma and TRAIL in human breast tumor cells.

Ruiz de Almodóvar C, López-Rivas A, Ruiz-Ruiz C.

Vitam Horm. 2004;67:291-318. Review.

PMID:
15110183
36.

Transcriptional regulation of the TRAIL-R3 gene.

Ruiz de Almodóvar C, López-Rivas A, Redondo JM, Rodríguez A.

Vitam Horm. 2004;67:51-63. Review.

PMID:
15110171
37.

The up-regulation of human caspase-8 by interferon-gamma in breast tumor cells requires the induction and action of the transcription factor interferon regulatory factor-1.

Ruiz-Ruiz C, Ruiz de Almodóvar C, Rodríguez A, Ortiz-Ferrón G, Redondo JM, López-Rivas A.

J Biol Chem. 2004 May 7;279(19):19712-20. Epub 2004 Mar 1.

38.

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) decoy receptor TRAIL-R3 is up-regulated by p53 in breast tumor cells through a mechanism involving an intronic p53-binding site.

Ruiz de Almodóvar C, Ruiz-Ruiz C, Rodríguez A, Ortiz-Ferrón G, Redondo JM, López-Rivas A.

J Biol Chem. 2004 Feb 6;279(6):4093-101. Epub 2003 Nov 17.

39.

Inhibition of glucose metabolism sensitizes tumor cells to death receptor-triggered apoptosis through enhancement of death-inducing signaling complex formation and apical procaspase-8 processing.

Muñoz-Pinedo C, Ruiz-Ruiz C, Ruiz de Almodóvar C, Palacios C, López-Rivas A.

J Biol Chem. 2003 Apr 11;278(15):12759-68. Epub 2003 Jan 29.

40.

Transcription initiation sites and promoter structure of the human TRAIL-R3 gene.

Ruiz de Almodóvar C, López-Rivas A, Redondo JM, Rodríguez A.

FEBS Lett. 2002 Nov 6;531(2):304-8.

41.

Death on the beach: a rosy forecast for the 21st century.

Muñoz-Pinedo C, Ruiz de Almodóvar C, Ruiz-Ruiz C.

Cell Death Differ. 2002 Sep;9(9):1026-9. No abstract available.

42.

The differential sensitivity of Bc1-2-overexpressing human breast tumor cells to TRAIL or doxorubicin-induced apoptosis is dependent on Bc1-2 protein levels.

Ruiz de Almodóvar C, Ruiz-Ruiz C, Muñoz-Pinedo C, Robledo G, López-Rivas A.

Oncogene. 2001 Oct 25;20(48):7128-33.

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