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Items: 1 to 50 of 170

1.

Retinol Saturase Knock-Out Mice are Characterized by Impaired Clearance of Apoptotic Cells and Develop Mild Autoimmunity.

Sarang Z, Sághy T, Budai Z, Ujlaky-Nagy L, Bedekovics J, Beke L, Méhes G, Nagy G, Rühl R, Moise AR, Palczewski K, Szondy Z.

Biomolecules. 2019 Nov 13;9(11). pii: E737. doi: 10.3390/biom9110737.

2.

Saturated and monounsaturated fatty acids in membranes are determined by the gene expression of their metabolizing enzymes SCD1 and ELOVL6 regulated by the intake of dietary fat.

Weiss-Hersh K, Garcia AL, Marosvölgyi T, Szklenár M, Decsi T, Rühl R.

Eur J Nutr. 2019 Nov 1. doi: 10.1007/s00394-019-02121-2. [Epub ahead of print]

PMID:
31676951
3.

Isotretinoin is indirectly effective in sebocytes.

Kovács D, Hegyi K, Szegedi A, Deák D, Póliska S, Rühl R, Zouboulis CC, Törőcsik D.

Br J Dermatol. 2019 Sep 28. doi: 10.1111/bjd.18562. [Epub ahead of print] No abstract available.

PMID:
31562833
4.

Structure, electrical conductivity and oxygen transport properties of perovskite-type oxides CaMn1-x-yTixFeyO3-δ.

Ruhl R, Song J, Thoréton V, Singh SP, Wiik K, Larring Y, Bouwmeester HJM.

Phys Chem Chem Phys. 2019 Oct 9;21(39):21824-21835. doi: 10.1039/c9cp04911h.

PMID:
31552399
5.

Apo-14´-Carotenoic Acid Is a Novel Endogenous and Bioactive Apo-Carotenoid.

Aydemir G, Domínguez M, de Lera AR, Mihaly J, Törőcsik D, Rühl R.

Nutrients. 2019 Sep 4;11(9). pii: E2084. doi: 10.3390/nu11092084.

6.

Brain ventricular volume changes induced by long-duration spaceflight.

Van Ombergen A, Jillings S, Jeurissen B, Tomilovskaya E, Rumshiskaya A, Litvinova L, Nosikova I, Pechenkova E, Rukavishnikov I, Manko O, Danylichev S, Rühl RM, Kozlovskaya IB, Sunaert S, Parizel PM, Sinitsyn V, Laureys S, Sijbers J, Zu Eulenburg P, Wuyts FL.

Proc Natl Acad Sci U S A. 2019 May 21;116(21):10531-10536. doi: 10.1073/pnas.1820354116. Epub 2019 May 6.

7.

Alternative retinoid X receptor (RXR) ligands.

Krężel W, Rühl R, de Lera AR.

Mol Cell Endocrinol. 2019 Jul 1;491:110436. doi: 10.1016/j.mce.2019.04.016. Epub 2019 Apr 23. Review.

PMID:
31026478
8.

Standardising practice in cardiology: reducing clinical variation and cost at Ochsner Health System.

Oravetz P, White CJ, Carmouche D, Swan N, Donaldson J, Ruhl R, Valdenor C, Paculdo D, Tran M, Peabody J.

Open Heart. 2019 Mar 22;6(1):e000994. doi: 10.1136/openhrt-2018-000994. eCollection 2019.

9.

β-Carotene in the human body: metabolic bioactivation pathways - from digestion to tissue distribution and excretion.

Bohn T, Desmarchelier C, El SN, Keijer J, van Schothorst E, Rühl R, Borel P.

Proc Nutr Soc. 2019 Feb;78(1):68-87. doi: 10.1017/S0029665118002641. Review.

PMID:
30747092
10.

Transcriptomic and lipidomic profiling of eicosanoid/docosanoid signalling in affected and non-affected skin of human atopic dermatitis patients.

Töröcsik D, Weise C, Gericke J, Szegedi A, Lucas R, Mihaly J, Worm M, Rühl R.

Exp Dermatol. 2019 Feb;28(2):177-189. doi: 10.1111/exd.13867.

PMID:
30575130
11.
12.

Brain Tissue-Volume Changes in Cosmonauts.

Van Ombergen A, Jillings S, Jeurissen B, Tomilovskaya E, Rühl RM, Rumshiskaya A, Nosikova I, Litvinova L, Annen J, Pechenkova EV, Kozlovskaya IB, Sunaert S, Parizel PM, Sinitsyn V, Laureys S, Sijbers J, Zu Eulenburg P, Wuyts FL.

N Engl J Med. 2018 Oct 25;379(17):1678-1680. doi: 10.1056/NEJMc1809011. No abstract available.

PMID:
30354959
13.

Reduced Carotenoid and Retinoid Concentrations and Altered Lycopene Isomer Ratio in Plasma of Atopic Dermatitis Patients.

Lucas R, Mihály J, Lowe GM, Graham DL, Szklenar M, Szegedi A, Töröcsik D, Rühl R.

Nutrients. 2018 Oct 1;10(10). pii: E1390. doi: 10.3390/nu10101390.

14.

Proteomic responses of carotenoid and retinol administration to Mongolian gerbils.

Bohn T, Planchon S, Leclercq CC, Renaut J, Mihaly J, Beke G, Rühl R.

Food Funct. 2018 Jul 17;9(7):3835-3844. doi: 10.1039/c8fo00278a.

PMID:
29951678
15.

MicroRNA regulation of the MRN complex impacts DNA damage, cellular senescence, and angiogenic signaling.

Espinosa-Diez C, Wilson R, Chatterjee N, Hudson C, Ruhl R, Hipfinger C, Helms E, Khan OF, Anderson DG, Anand S.

Cell Death Dis. 2018 May 24;9(6):632. doi: 10.1038/s41419-018-0690-y.

16.

microRNA-451a regulates colorectal cancer proliferation in response to radiation.

Ruhl R, Rana S, Kelley K, Espinosa-Diez C, Hudson C, Lanciault C, Thomas CR Jr, Liana Tsikitis V, Anand S.

BMC Cancer. 2018 May 3;18(1):517. doi: 10.1186/s12885-018-4370-1.

17.

Functional correlate and delineated connectivity pattern of human motion aftereffect responses substantiate a subjacent visual-vestibular interaction.

Rühl RM, Bauermann T, Dieterich M, Zu Eulenburg P.

Neuroimage. 2018 Jul 1;174:22-34. doi: 10.1016/j.neuroimage.2018.02.057. Epub 2018 Mar 14.

PMID:
29518571
18.

A Review About Lycopene-Induced Nuclear Hormone Receptor Signalling in Inflammation and Lipid Metabolism via still Unknown Endogenous Apo-10´-Lycopenoids.

Caris-Veyrat C, Garcia AL, Reynaud E, Lucas R, Aydemir G, Rühl R.

Int J Vitam Nutr Res. 2016 Feb;86(1-2):62-70. doi: 10.1024/0300-9831/a000404. Epub 2017 Oct 20.

PMID:
29052471
19.

Understanding and Resetting Radiation Sensitivity in Rectal Cancer.

Kelley KA, Ruhl RA, Rana SR, Dewey E, Espinosa C, Thomas CR Jr, Martindale RG, Anand S, Tsikitis VL.

Ann Surg. 2017 Oct;266(4):610-616. doi: 10.1097/SLA.0000000000002409.

PMID:
28742699
20.

Sebum lipids influence macrophage polarization and activation.

Lovászi M, Mattii M, Eyerich K, Gácsi A, Csányi E, Kovács D, Rühl R, Szegedi A, Kemény L, Ståhle M, Zouboulis CC, Eyerich S, Törőcsik D.

Br J Dermatol. 2017 Dec;177(6):1671-1682. doi: 10.1111/bjd.15754. Epub 2017 Nov 28.

PMID:
28646583
21.

Colorectal Cancer Liver Metastasis: Evolving Paradigms and Future Directions.

Zarour LR, Anand S, Billingsley KG, Bisson WH, Cercek A, Clarke MF, Coussens LM, Gast CE, Geltzeiler CB, Hansen L, Kelley KA, Lopez CD, Rana SR, Ruhl R, Tsikitis VL, Vaccaro GM, Wong MH, Mayo SC.

Cell Mol Gastroenterol Hepatol. 2017 Jan 20;3(2):163-173. doi: 10.1016/j.jcmgh.2017.01.006. eCollection 2017 Mar. Review.

22.

Interactions of retinoids with the ABC transporters P-glycoprotein and Breast Cancer Resistance Protein.

Tarapcsák S, Szalóki G, Telbisz Á, Gyöngy Z, Matúz K, Csősz É, Nagy P, Holb IJ, Rühl R, Nagy L, Szabó G, Goda K.

Sci Rep. 2017 Feb 1;7:41376. doi: 10.1038/srep41376.

23.

Sebaceous Gland-Rich Skin Is Characterized by TSLP Expression and Distinct Immune Surveillance Which Is Disturbed in Rosacea.

Dajnoki Z, Béke G, Kapitány A, Mócsai G, Gáspár K, Rühl R, Hendrik Z, Juhász I, Zouboulis CC, Bácsi A, Bíró T, Törőcsik D, Szegedi A.

J Invest Dermatol. 2017 May;137(5):1114-1125. doi: 10.1016/j.jid.2016.12.025. Epub 2017 Jan 25.

24.

Host-related factors explaining interindividual variability of carotenoid bioavailability and tissue concentrations in humans.

Bohn T, Desmarchelier C, Dragsted LO, Nielsen CS, Stahl W, Rühl R, Keijer J, Borel P.

Mol Nutr Food Res. 2017 Jun;61(6). doi: 10.1002/mnfr.201600685. Epub 2017 Feb 27. Review.

25.

MicroRNA regulation of endothelial TREX1 reprograms the tumour microenvironment.

Wilson R, Espinosa-Diez C, Kanner N, Chatterjee N, Ruhl R, Hipfinger C, Advani SJ, Li J, Khan OF, Franovic A, Weis SM, Kumar S, Coussens LM, Anderson DG, Chen CC, Cheresh DA, Anand S.

Nat Commun. 2016 Nov 25;7:13597. doi: 10.1038/ncomms13597.

26.

Alterations in Epidermal Eicosanoid Metabolism Contribute to Inflammation and Impaired Late Differentiation in FLG-Mutated Atopic Dermatitis.

Blunder S, Rühl R, Moosbrugger-Martinz V, Krimmel C, Geisler A, Zhu H, Crumrine D, Elias PM, Gruber R, Schmuth M, Dubrac S.

J Invest Dermatol. 2017 Mar;137(3):706-715. doi: 10.1016/j.jid.2016.09.034. Epub 2016 Oct 26.

27.

RhoA controls retinoid signaling by ROCK dependent regulation of retinol metabolism.

García-Mariscal A, Peyrollier K, Basse A, Pedersen E, Rühl R, van Hengel J, Brakebusch C.

Small GTPases. 2018 Sep 3;9(5):433-444. doi: 10.1080/21541248.2016.1248272. Epub 2016 Nov 16.

28.

Reduced adiponectin expression after high-fat diet is associated with selective up-regulation of ALDH1A1 and further retinoic acid receptor signaling in adipose tissue.

Landrier JF, Kasiri E, Karkeni E, Mihály J, Béke G, Weiss K, Lucas R, Aydemir G, Salles J, Walrand S, de Lera AR, Rühl R.

FASEB J. 2017 Jan;31(1):203-211. doi: 10.1096/fj.201600263RR. Epub 2016 Oct 11.

29.

Lycopene supplementation restores vitamin A deficiency in mice and possesses thereby partial pro-vitamin A activity transmitted via RAR signaling.

Aydemir G, Kasiri Y, Bartók EM, Birta E, Fröhlich K, Böhm V, Mihaly J, Rühl R.

Mol Nutr Food Res. 2016 Nov;60(11):2413-2420. doi: 10.1002/mnfr.201600031. Epub 2016 Jul 29.

PMID:
27296317
30.

Relationship Between All-trans-13,14-Dihydro Retinoic Acid and Pancreatic Adenocarcinoma.

Bazhin AV, Bleul T, de Lera AR, Werner J, Rühl R.

Pancreas. 2016 Jul;45(6):e29-31. doi: 10.1097/MPA.0000000000000601. No abstract available.

PMID:
27295537
31.

An Endogenous Mammalian Retinoid X Receptor Ligand, At Last!

de Lera ÁR, Krezel W, Rühl R.

ChemMedChem. 2016 May 19;11(10):1027-37. doi: 10.1002/cmdc.201600105. Epub 2016 May 6.

PMID:
27151148
32.

Determinants of epoxy allergy in the construction industry: a case-control study.

Spee T, Timmerman JG, Rühl R, Kersting K, Heederik DJ, Smit LA.

Contact Dermatitis. 2016 May;74(5):259-66. doi: 10.1111/cod.12529. Epub 2016 Jan 29.

PMID:
26822500
33.

Decreased peroxisome proliferator-activated receptor γ level and signalling in sebaceous glands of patients with acne vulgaris.

Dozsa A, Mihaly J, Dezso B, Csizmadia E, Keresztessy T, Marko L, Rühl R, Remenyik E, Nagy L.

Clin Exp Dermatol. 2016 Jul;41(5):547-51. doi: 10.1111/ced.12794. Epub 2016 Jan 23.

PMID:
26800853
34.

Dietary regulation of adiponectin by direct and indirect lipid activators of nuclear hormone receptors.

Rühl R, Landrier JF.

Mol Nutr Food Res. 2016 Jan;60(1):175-84. doi: 10.1002/mnfr.201500619. Epub 2015 Dec 10. Review.

PMID:
26610729
35.

TSLP expression in the skin is mediated via RARγ-RXR pathways.

Mihály J, Gericke J, Lucas R, de Lera AR, Alvarez S, Törőcsik D, Rühl R.

Immunobiology. 2016 Feb;221(2):161-5. doi: 10.1016/j.imbio.2015.09.013. Epub 2015 Sep 10.

PMID:
26531761
36.

Sebocytes differentially express and secrete adipokines.

Kovács D, Lovászi M, Póliska S, Oláh A, Bíró T, Veres I, Zouboulis CC, Ståhle M, Rühl R, Remenyik É, Törőcsik D.

Exp Dermatol. 2016 Mar;25(3):194-9. doi: 10.1111/exd.12879. Epub 2016 Jan 11.

PMID:
26476096
37.

9-cis-13,14-Dihydroretinoic Acid Is an Endogenous Retinoid Acting as RXR Ligand in Mice.

Rühl R, Krzyżosiak A, Niewiadomska-Cimicka A, Rochel N, Szeles L, Vaz B, Wietrzych-Schindler M, Álvarez S, Szklenar M, Nagy L, de Lera AR, Krężel W.

PLoS Genet. 2015 Jun 1;11(6):e1005213. doi: 10.1371/journal.pgen.1005213. eCollection 2015 Jun.

38.

Vitamin A-deficient diet accelerated atherogenesis in apolipoprotein E(-/-) mice and dietary β-carotene prevents this consequence.

Relevy NZ, Harats D, Harari A, Ben-Amotz A, Bitzur R, Rühl R, Shaish A.

Biomed Res Int. 2015;2015:758723. doi: 10.1155/2015/758723. Epub 2015 Feb 23.

39.

LRAT overexpression diminishes intracellular levels of biologically active retinoids and reduces retinoid antitumor efficacy in the murine melanoma B16F10 cell line.

Amann PM, Czaja K, Bazhin AV, Rühl R, Eichmüller SB, Merk HF, Baron JM.

Skin Pharmacol Physiol. 2015;28(4):205-12.

PMID:
25721651
40.

Poly(ADP) ribose polymerase-1 ablation alters eicosanoid and docosanoid signaling and metabolism in a murine model of contact hypersensitivity.

Kiss B, Szántó M, Szklenár M, Brunyánszki A, Marosvölgyi T, Sárosi E, Remenyik É, Gergely P, Virág L, Decsi T, Rühl R, Bai P.

Mol Med Rep. 2015 Apr;11(4):2861-7. doi: 10.3892/mmr.2014.3044. Epub 2014 Dec 4.

PMID:
25482287
41.

Knockdown of lecithin retinol acyltransferase increases all-trans retinoic acid levels and restores retinoid sensitivity in malignant melanoma cells.

Amann PM, Czaja K, Bazhin AV, Rühl R, Skazik C, Heise R, Marquardt Y, Eichmüller SB, Merk HF, Baron JM.

Exp Dermatol. 2014 Nov;23(11):832-7. doi: 10.1111/exd.12548. Epub 2014 Oct 10.

PMID:
25236354
42.

Leptin promotes a proinflammatory lipid profile and induces inflammatory pathways in human SZ95 sebocytes.

Törőcsik D, Kovács D, Camera E, Lovászi M, Cseri K, Nagy GG, Molinaro R, Rühl R, Tax G, Szabó K, Picardo M, Kemény L, Zouboulis CC, Remenyik É.

Br J Dermatol. 2014 Dec;171(6):1326-35. doi: 10.1111/bjd.13229. Epub 2014 Nov 20.

PMID:
24975960
43.

Steroid concentrations in patients with atopic dermatitis: reduced plasma dehydroepiandrosterone sulfate and increased cortisone levels.

Mihály J, Sonntag D, Krebiehl G, Szegedi A, Töröcsik D, Rühl R.

Br J Dermatol. 2015 Jan;172(1):285-8. doi: 10.1111/bjd.13219. Epub 2014 Nov 22. No abstract available. Erratum in: Br J Dermatol. 2015 Jun;172(6):1688.

PMID:
24974914
44.

Increased FADS2-derived n-6 PUFAs and reduced n-3 PUFAs in plasma of atopic dermatitis patients.

Mihály J, Marosvölgyi T, Szegedi A, Köröskényi K, Lucas R, Törőcsik D, Garcia AL, Decsi T, Rühl R.

Skin Pharmacol Physiol. 2014;27(5):242-8. doi: 10.1159/000358290. Epub 2014 May 20.

PMID:
24854601
45.

Macrophages engulfing apoptotic cells produce nonclassical retinoids to enhance their phagocytic capacity.

Sarang Z, Joós G, Garabuczi É, Rühl R, Gregory CD, Szondy Z.

J Immunol. 2014 Jun 15;192(12):5730-8. doi: 10.4049/jimmunol.1400284. Epub 2014 May 21.

46.

Reduced retinoids and retinoid receptors' expression in pancreatic cancer: A link to patient survival.

Bleul T, Rühl R, Bulashevska S, Karakhanova S, Werner J, Bazhin AV.

Mol Carcinog. 2015 Sep;54(9):870-9. doi: 10.1002/mc.22158. Epub 2014 Apr 11.

PMID:
24729540
47.

Hypoxia reduces the efficiency of elisidepsin by inhibiting hydroxylation and altering the structure of lipid rafts.

Király A, Váradi T, Hajdu T, Rühl R, Galmarini CM, Szöllősi J, Nagy P.

Mar Drugs. 2013 Dec 2;11(12):4858-75. doi: 10.3390/md11124858.

48.

Effect of high versus low doses of fat and vitamin A dietary supplementation on fatty acid composition of phospholipids in mice.

Weiss K, Mihály J, Liebisch G, Marosvölgyi T, Garcia AL, Schmitz G, Decsi T, Rühl R.

Genes Nutr. 2014 Jan;9(1):368. doi: 10.1007/s12263-013-0368-0. Epub 2013 Dec 4.

49.

Downregulation of STRA6 expression in epidermal keratinocytes leads to hyperproliferation-associated differentiation in both in vitro and in vivo skin models.

Skazik C, Amann PM, Heise R, Marquardt Y, Czaja K, Kim A, Rühl R, Kurschat P, Merk HF, Bickers DR, Baron JM.

J Invest Dermatol. 2014 Jun;134(6):1579-1588. doi: 10.1038/jid.2013.507. Epub 2013 Nov 27.

50.

PPARγ-mediated and arachidonic acid-dependent signaling is involved in differentiation and lipid production of human sebocytes.

Dozsa A, Dezso B, Toth BI, Bacsi A, Poliska S, Camera E, Picardo M, Zouboulis CC, Bíró T, Schmitz G, Liebisch G, Rühl R, Remenyik E, Nagy L.

J Invest Dermatol. 2014 Apr;134(4):910-920. doi: 10.1038/jid.2013.413. Epub 2013 Oct 15.

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