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Items: 1 to 50 of 76

1.

A new lipoxygenase from the agaric fungus Agrocybe aegerita: Biochemical characterization and kinetic properties.

Karrer D, Rühl M.

PLoS One. 2019 Jun 19;14(6):e0218625. doi: 10.1371/journal.pone.0218625. eCollection 2019.

2.

New terpenoids from the fermentation broth of the edible mushroom Cyclocybe aegerita.

Surup F, Hennicke F, Sella N, Stroot M, Bernecker S, Pfütze S, Stadler M, Rühl M.

Beilstein J Org Chem. 2019 Apr 30;15:1000-1007. doi: 10.3762/bjoc.15.98. eCollection 2019.

3.

Signal peptide replacement resulted in recombinant homologous expression of laccase Lcc8 in Coprinopsis cinerea.

Schulze M, Geisler L, Majcherczyk A, Rühl M.

AMB Express. 2019 Mar 15;9(1):36. doi: 10.1186/s13568-019-0761-1.

4.

Aroma Profile Analyses of Filamentous Fungi Cultivated on Solid Substrates.

Orban A, Fraatz MA, Rühl M.

Adv Biochem Eng Biotechnol. 2019;169:85-107. doi: 10.1007/10_2019_87. Review.

PMID:
30828753
5.

Melleolides from Honey Mushroom Inhibit 5-Lipoxygenase via Cys159.

König S, Romp E, Krauth V, Rühl M, Dörfer M, Liening S, Hofmann B, Häfner AK, Steinhilber D, Karas M, Garscha U, Hoffmeister D, Werz O.

Cell Chem Biol. 2019 Jan 17;26(1):60-70.e4. doi: 10.1016/j.chembiol.2018.10.010. Epub 2018 Nov 8.

PMID:
30415966
6.

Enrichment of vitamin D2 in mycelium from submerged cultures of the agaric mushroom Pleurotus sapidus.

Ahlborn J, Calzolari N, Spielmeyer A, Avci SS, Zimmer M, Rühl M.

J Food Sci Technol. 2018 Sep;55(9):3833-3839. doi: 10.1007/s13197-018-3290-z. Epub 2018 Jun 20.

PMID:
30150844
7.

Nitro-fatty acids are formed in response to virus infection and are potent inhibitors of STING palmitoylation and signaling.

Hansen AL, Buchan GJ, Rühl M, Mukai K, Salvatore SR, Ogawa E, Andersen SD, Iversen MB, Thielke AL, Gunderstofte C, Motwani M, Møller CT, Jakobsen AS, Fitzgerald KA, Roos J, Lin R, Maier TJ, Goldbach-Mansky R, Miner CA, Qian W, Miner JJ, Rigby RE, Rehwinkel J, Jakobsen MR, Arai H, Taguchi T, Schopfer FJ, Olagnier D, Holm CK.

Proc Natl Acad Sci U S A. 2018 Aug 14;115(33):E7768-E7775. doi: 10.1073/pnas.1806239115. Epub 2018 Jul 30.

8.

Laccase production and pellet morphology of Coprinopsis cinerea transformants in liquid shake flask cultures.

Rühl M, Lange K, Kües U.

Appl Microbiol Biotechnol. 2018 Sep;102(18):7849-7863. doi: 10.1007/s00253-018-9227-7. Epub 2018 Jul 21.

PMID:
30032435
9.

Elucidation of chemical modifier reactivity towards peptides and proteins and the analysis of specific fragmentation by matrix-assisted laser desorption/ionization collision-induced dissociation tandem mass spectrometry.

Rühl M, Kühn B, Roos J, Maier TJ, Steinhilber D, Karas M.

Rapid Commun Mass Spectrom. 2018 Jul 2. doi: 10.1002/rcm.8223. [Epub ahead of print]

PMID:
29964304
10.

Anti-inflammatory nitro-fatty acids suppress tumor growth by triggering mitochondrial dysfunction and activation of the intrinsic apoptotic pathway in colorectal cancer cells.

Kühn B, Brat C, Fettel J, Hellmuth N, Maucher IV, Bulut U, Hock KJ, Grimmer J, Manolikakes G, Rühl M, Kühn A, Zacharowski K, Matrone C, Urbschat A, Roos J, Steinhilber D, Maier TJ.

Biochem Pharmacol. 2018 Sep;155:48-60. doi: 10.1016/j.bcp.2018.06.014. Epub 2018 Jun 15.

PMID:
29909078
11.
12.

GIGANTEA-like genes control seasonal growth cessation in Populus.

Ding J, Böhlenius H, Rühl MG, Chen P, Sane S, Zambrano JA, Zheng B, Eriksson ME, Nilsson O.

New Phytol. 2018 Jun;218(4):1491-1503. doi: 10.1111/nph.15087. Epub 2018 Mar 13.

13.

The genome sequence of the commercially cultivated mushroom Agrocybe aegerita reveals a conserved repertoire of fruiting-related genes and a versatile suite of biopolymer-degrading enzymes.

Gupta DK, Rühl M, Mishra B, Kleofas V, Hofrichter M, Herzog R, Pecyna MJ, Sharma R, Kellner H, Hennicke F, Thines M.

BMC Genomics. 2018 Jan 15;19(1):48. doi: 10.1186/s12864-017-4430-y.

14.

Mercury evidence for pulsed volcanism during the end-Triassic mass extinction.

Percival LME, Ruhl M, Hesselbo SP, Jenkyns HC, Mather TA, Whiteside JH.

Proc Natl Acad Sci U S A. 2017 Jul 25;114(30):7929-7934. doi: 10.1073/pnas.1705378114. Epub 2017 Jun 19.

15.

Cognitive deficits in patients with a chronic vestibular failure.

Popp P, Wulff M, Finke K, Rühl M, Brandt T, Dieterich M.

J Neurol. 2017 Mar;264(3):554-563. doi: 10.1007/s00415-016-8386-7. Epub 2017 Jan 10.

PMID:
28074268
16.

Michael acceptor containing drugs are a novel class of 5-lipoxygenase inhibitor targeting the surface cysteines C416 and C418.

Maucher IV, Rühl M, Kretschmer SB, Hofmann B, Kühn B, Fettel J, Vogel A, Flügel KT, Manolikakes G, Hellmuth N, Häfner AK, Golghalyani V, Ball AK, Piesche M, Matrone C, Geisslinger G, Parnham MJ, Karas M, Steinhilber D, Roos J, Maier TJ.

Biochem Pharmacol. 2017 Feb 1;125:55-74. doi: 10.1016/j.bcp.2016.11.004. Epub 2016 Nov 4.

PMID:
27823964
17.

Willingness to Be a Brain Donor: A Survey of Research Volunteers From 4 Racial/Ethnic Groups.

Boise L, Hinton L, Rosen HJ, Ruhl MC, Dodge H, Mattek N, Albert M, Denny A, Grill JD, Hughes T, Lingler JH, Morhardt D, Parfitt F, Peterson-Hazan S, Pop V, Rose T, Shah RC.

Alzheimer Dis Assoc Disord. 2017 Apr-Jun;31(2):135-140. doi: 10.1097/WAD.0000000000000174.

18.

Real World Data in Adaptive Biomedical Innovation: A Framework for Generating Evidence Fit for Decision-Making.

Schneeweiss S, Eichler HG, Garcia-Altes A, Chinn C, Eggimann AV, Garner S, Goettsch W, Lim R, Löbker W, Martin D, Müller T, Park BJ, Platt R, Priddy S, Ruhl M, Spooner A, Vannieuwenhuyse B, Willke RJ.

Clin Pharmacol Ther. 2016 Dec;100(6):633-646. doi: 10.1002/cpt.512. Epub 2016 Oct 19.

PMID:
27627027
19.

Characterization of the molecular mechanism of 5-lipoxygenase inhibition by 2-aminothiazoles.

Kretschmer SB, Woltersdorf S, Vogt D, Lillich FF, Rühl M, Karas M, Maucher IV, Roos J, Häfner AK, Kaiser A, Wurglics M, Schubert-Zsilavecz M, Angioni C, Geisslinger G, Stark H, Steinhilber D, Hofmann B.

Biochem Pharmacol. 2017 Jan 1;123:52-62. doi: 10.1016/j.bcp.2016.09.021. Epub 2016 Sep 23.

PMID:
27671344
20.

Circadian and Plastid Signaling Pathways Are Integrated to Ensure Correct Expression of the CBF and COR Genes during Photoperiodic Growth.

Norén L, Kindgren P, Stachula P, Rühl M, Eriksson ME, Hurry V, Strand Å.

Plant Physiol. 2016 Jun;171(2):1392-406. doi: 10.1104/pp.16.00374. Epub 2016 Apr 14.

21.

An aryl-alcohol oxidase of Pleurotus sapidus: heterologous expression, characterization, and application in a 2-enzyme system.

Galperin I, Javeed A, Luig H, Lochnit G, Rühl M.

Appl Microbiol Biotechnol. 2016 Sep;100(18):8021-30. doi: 10.1007/s00253-016-7567-8. Epub 2016 May 2.

PMID:
27138199
22.

Will My Soul Go to Heaven If They Take My Brain? Beliefs and Worries About Brain Donation Among Four Ethnic Groups.

Boise L, Hinton L, Rosen HJ, Ruhl M.

Gerontologist. 2017 Aug 1;57(4):719-734. doi: 10.1093/geront/gnv683.

23.

Jurassic climate mode governed by ocean gateway.

Korte C, Hesselbo SP, Ullmann CV, Dietl G, Ruhl M, Schweigert G, Thibault N.

Nat Commun. 2015 Dec 11;6:10015. doi: 10.1038/ncomms10015.

24.

DECISION-MAKING ALIGNED WITH RAPID-CYCLE EVALUATION IN HEALTH CARE.

Schneeweiss S, Shrank WH, Ruhl M, Maclure M.

Int J Technol Assess Health Care. 2015 Jan;31(4):214-22. doi: 10.1017/S0266462315000410. Epub 2015 Nov 20.

PMID:
26585440
25.

Depolymerization of lignosulfonates by submerged cultures of the basidiomycete Irpex consors and cloning of a putative versatile peroxidase.

Imami A, Riemer S, Schulze M, Amelung F, Gorshkov V, Rühl M, Ammenn J, Zorn H.

Enzyme Microb Technol. 2015 Dec;81:8-15. doi: 10.1016/j.enzmictec.2015.07.007. Epub 2015 Jul 28.

PMID:
26453467
26.

Prolyl-specific peptidases for applications in food protein hydrolysis.

Mika N, Zorn H, Rühl M.

Appl Microbiol Biotechnol. 2015 Oct;99(19):7837-46. doi: 10.1007/s00253-015-6838-0. Epub 2015 Aug 4. Review.

PMID:
26239067
27.

Evolution of CONSTANS Regulation and Function after Gene Duplication Produced a Photoperiodic Flowering Switch in the Brassicaceae.

Simon S, Rühl M, de Montaigu A, Wötzel S, Coupland G.

Mol Biol Evol. 2015 Sep;32(9):2284-301. doi: 10.1093/molbev/msv110. Epub 2015 May 13.

28.

The effect of a repeated immunoadsorption in patients with dilated cardiomyopathy after recurrence of severe heart failure symptoms.

Reinthaler M, Empen K, Herda LR, Schwabe A, Rühl M, Dörr M, Felix SB.

J Clin Apher. 2015 Aug;30(4):217-23. doi: 10.1002/jca.21364. Epub 2014 Oct 27.

PMID:
25346275
29.

Effect of a Jurassic oceanic anoxic event on belemnite ecology and evolution.

Ullmann CV, Thibault N, Ruhl M, Hesselbo SP, Korte C.

Proc Natl Acad Sci U S A. 2014 Jul 15;111(28):10073-6. doi: 10.1073/pnas.1320156111. Epub 2014 Jun 30.

30.

Non-growing Rhodopseudomonas palustris increases the hydrogen gas yield from acetate by shifting from the glyoxylate shunt to the tricarboxylic acid cycle.

McKinlay JB, Oda Y, Rühl M, Posto AL, Sauer U, Harwood CS.

J Biol Chem. 2014 Jan 24;289(4):1960-70. doi: 10.1074/jbc.M113.527515. Epub 2013 Dec 3.

31.

Insect-derived enzymes: a treasure for industrial biotechnology and food biotechnology.

Mika N, Zorn H, Rühl M.

Adv Biochem Eng Biotechnol. 2013;136:1-17. doi: 10.1007/10_2013_204.

PMID:
23881056
32.

Food and feed enzymes.

Fraatz MA, Rühl M, Zorn H.

Adv Biochem Eng Biotechnol. 2014;143:229-56. doi: 10.1007/10_2013_235. Review.

PMID:
23873095
33.

Willingness of older adults to share data and privacy concerns after exposure to unobtrusive in-home monitoring.

Boise L, Wild K, Mattek N, Ruhl M, Dodge HH, Kaye J.

Gerontechnology. 2013;11(3):428-435.

34.

Lcc1 and Lcc5 are the main laccases secreted in liquid cultures of Coprinopsis cinerea strains.

Rühl M, Majcherczyk A, Kües U.

Antonie Van Leeuwenhoek. 2013 May;103(5):1029-39. doi: 10.1007/s10482-013-9883-7. Epub 2013 Jan 23.

35.

The synthetic hydroxyproline-containing collagen analogue (Gly-Pro-Hyp)10 ameliorates acute DSS colitis.

Heimesaat MM, Heilmann K, Kühl AA, Erben U, Rühl M, Fischer A, Farndale RW, Bereswill S, Göbel UB, Zeitz M, Somasundaram R, Freise C.

Eur J Microbiol Immunol (Bp). 2012 Sep;2(3):192-200. doi: 10.1556/EuJMI.2.2012.3.4. Epub 2012 Sep 10.

36.

Susceptibility to chronic hepatitis C virus infection is influenced by sequence differences in immunodominant CD8+ T cell epitopes.

Ziegler S, Ruhl M, Tenckhoff H, Wiese M, Heinemann FM, Horn PA, Spengler U, Neumann-Haefelin C, Nattermann J, Timm J; East-German HCV Study Group.

J Hepatol. 2013 Jan;58(1):24-30. doi: 10.1016/j.jhep.2012.08.016. Epub 2012 Aug 25.

PMID:
22925811
37.

13C-flux analysis reveals NADPH-balancing transhydrogenation cycles in stationary phase of nitrogen-starving Bacillus subtilis.

Rühl M, Le Coq D, Aymerich S, Sauer U.

J Biol Chem. 2012 Aug 10;287(33):27959-70. doi: 10.1074/jbc.M112.366492. Epub 2012 Jun 27.

38.

Absolute configuration of antifibrotic (+)-episesamin isolated from Lindera obtusiloba BLUME.

Trowitzsch-Kienast W, Rühl M, Kim KY, Emmerling F, Erbenb U, Somasundaram R, Freise C.

Z Naturforsch C. 2011 Sep-Oct;66(9-10):460-4.

PMID:
22191210
39.
40.

Escape from a dominant HLA-B*15-restricted CD8+ T cell response against hepatitis C virus requires compensatory mutations outside the epitope.

Ruhl M, Chhatwal P, Strathmann H, Kuntzen T, Bankwitz D, Skibbe K, Walker A, Heinemann FM, Horn PA, Allen TM, Hoffmann D, Pietschmann T, Timm J.

J Virol. 2012 Jan;86(2):991-1000. doi: 10.1128/JVI.05603-11. Epub 2011 Nov 9.

41.

Assessing the comparative effectiveness of newly marketed medications: methodological challenges and implications for drug development.

Schneeweiss S, Gagne JJ, Glynn RJ, Ruhl M, Rassen JA.

Clin Pharmacol Ther. 2011 Dec;90(6):777-90. doi: 10.1038/clpt.2011.235. Epub 2011 Nov 2.

PMID:
22048230
42.

Collisional fragmentation of central carbon metabolites in LC-MS/MS increases precision of ¹³C metabolic flux analysis.

Rühl M, Rupp B, Nöh K, Wiechert W, Sauer U, Zamboni N.

Biotechnol Bioeng. 2012 Mar;109(3):763-71. doi: 10.1002/bit.24344. Epub 2011 Oct 28.

PMID:
22012626
43.

Multiple multi-copper oxidase gene families in basidiomycetes - what for?

Kües U, Rühl M.

Curr Genomics. 2011 Apr;12(2):72-94. doi: 10.2174/138920211795564377.

44.

Atmospheric carbon injection linked to end-Triassic mass extinction.

Ruhl M, Bonis NR, Reichart GJ, Sinninghe Damsté JS, Kürschner WM.

Science. 2011 Jul 22;333(6041):430-4. doi: 10.1126/science.1204255.

45.

CD8+ T-cell response promotes evolution of hepatitis C virus nonstructural proteins.

Ruhl M, Knuschke T, Schewior K, Glavinic L, Neumann-Haefelin C, Chang DI, Klein M, Heinemann FM, Tenckhoff H, Wiese M, Horn PA, Viazov S, Spengler U, Roggendorf M, Scherbaum N, Nattermann J, Hoffmann D, Timm J; East German HCV Study Group.

Gastroenterology. 2011 Jun;140(7):2064-73. doi: 10.1053/j.gastro.2011.02.060. Epub 2011 Mar 2.

PMID:
21376049
46.

Subpopulation-specific metabolic pathway usage in mixed cultures as revealed by reporter protein-based 13C analysis.

Rühl M, Hardt WD, Sauer U.

Appl Environ Microbiol. 2011 Mar;77(5):1816-21. doi: 10.1128/AEM.02696-10. Epub 2011 Jan 7.

47.

Coexpression of PD-1, 2B4, CD160 and KLRG1 on exhausted HCV-specific CD8+ T cells is linked to antigen recognition and T cell differentiation.

Bengsch B, Seigel B, Ruhl M, Timm J, Kuntz M, Blum HE, Pircher H, Thimme R.

PLoS Pathog. 2010 Jun 10;6(6):e1000947. doi: 10.1371/journal.ppat.1000947.

48.

Dynamic flux responses in riboflavin overproducing Bacillus subtilis to increasing glucose limitation in fed-batch culture.

Rühl M, Zamboni N, Sauer U.

Biotechnol Bioeng. 2010 Mar 1;105(4):795-804. doi: 10.1002/bit.22591.

PMID:
19882734
49.

Compensatory base changes illuminate morphologically difficult taxonomy.

Ruhl MW, Wolf M, Jenkins TM.

Mol Phylogenet Evol. 2010 Feb;54(2):664-9. doi: 10.1016/j.ympev.2009.07.036. Epub 2009 Aug 4.

PMID:
19660561
50.

Arabidopsis DOF transcription factors act redundantly to reduce CONSTANS expression and are essential for a photoperiodic flowering response.

Fornara F, Panigrahi KC, Gissot L, Sauerbrunn N, Rühl M, Jarillo JA, Coupland G.

Dev Cell. 2009 Jul;17(1):75-86. doi: 10.1016/j.devcel.2009.06.015.

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