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Items: 1 to 50 of 239

1.

Impaired adult neurogenesis is an early event in Alzheimer's disease neurodegeneration, mediated by intracellular Aβ oligomers.

Scopa C, Marrocco F, Latina V, Ruggeri F, Corvaglia V, La Regina F, Ammassari-Teule M, Middei S, Amadoro G, Meli G, Scardigli R, Cattaneo A.

Cell Death Differ. 2019 Oct 7. doi: 10.1038/s41418-019-0409-3. [Epub ahead of print]

PMID:
31591472
2.

Characterizing Individual Protein Aggregates by Infrared Nanospectroscopy and Atomic Force Microscopy.

Ruggeri FS, Šneideris T, Chia S, Vendruscolo M, Knowles TPJ.

J Vis Exp. 2019 Sep 12;(151). doi: 10.3791/60108.

PMID:
31566623
3.

Infrared nanospectroscopic mapping of a single metaphase chromosome.

Lipiec E, Ruggeri FS, Benadiba C, Borkowska AM, Kobierski JD, Miszczyk J, Wood BR, Deacon GB, Kulik A, Dietler G, Kwiatek WM.

Nucleic Acids Res. 2019 Oct 10;47(18):e108. doi: 10.1093/nar/gkz630.

4.

Soluble aggregates present in cerebrospinal fluid change in size and mechanism of toxicity during Alzheimer's disease progression.

De S, Whiten DR, Ruggeri FS, Hughes C, Rodrigues M, Sideris DI, Taylor CG, Aprile FA, Muyldermans S, Knowles TPJ, Vendruscolo M, Bryant C, Blennow K, Skoog I, Kern S, Zetterberg H, Klenerman D.

Acta Neuropathol Commun. 2019 Jul 26;7(1):120. doi: 10.1186/s40478-019-0777-4.

5.

Analysis of αB-crystallin polydispersity in solution through native microfluidic electrophoresis.

Wright MA, Ruggeri FS, Saar KL, Challa PK, Benesch JLP, Knowles TPJ.

Analyst. 2019 Jul 21;144(14):4413-4424. doi: 10.1039/c9an00382g. Epub 2019 Jun 19.

PMID:
31215547
6.

Virus like particles of GII.4 norovirus bind Toll Like Receptors 2 and 5.

Ponterio E, Mariotti S, Tabolacci C, Ruggeri FM, Nisini R.

Immunol Lett. 2019 May 30. pii: S0165-2478(19)30160-9. doi: 10.1016/j.imlet.2019.05.016. [Epub ahead of print]

PMID:
31154053
7.

Different soluble aggregates of Aβ42 can give rise to cellular toxicity through different mechanisms.

De S, Wirthensohn DC, Flagmeier P, Hughes C, Aprile FA, Ruggeri FS, Whiten DR, Emin D, Xia Z, Varela JA, Sormanni P, Kundel F, Knowles TPJ, Dobson CM, Bryant C, Vendruscolo M, Klenerman D.

Nat Commun. 2019 Apr 4;10(1):1541. doi: 10.1038/s41467-019-09477-3.

8.

Fabrication and Characterization of Reconstituted Silk Microgels for the Storage and Release of Small Molecules.

Liu X, Toprakcioglu Z, Dear AJ, Levin A, Ruggeri FS, Taylor CG, Hu M, Kumita JR, Andreasen M, Dobson CM, Shimanovich U, Knowles TPJ.

Macromol Rapid Commun. 2019 Apr;40(8):e1800898. doi: 10.1002/marc.201800898. Epub 2019 Mar 6.

PMID:
30840348
9.

Atomic force microscopy for single molecule characterisation of protein aggregation.

Ruggeri FS, Šneideris T, Vendruscolo M, Knowles TPJ.

Arch Biochem Biophys. 2019 Mar 30;664:134-148. doi: 10.1016/j.abb.2019.02.001. Epub 2019 Feb 8. Review.

10.

Trodusquemine enhances Aβ42 aggregation but suppresses its toxicity by displacing oligomers from cell membranes.

Limbocker R, Chia S, Ruggeri FS, Perni M, Cascella R, Heller GT, Meisl G, Mannini B, Habchi J, Michaels TCT, Challa PK, Ahn M, Casford ST, Fernando N, Xu CK, Kloss ND, Cohen SIA, Kumita JR, Cecchi C, Zasloff M, Linse S, Knowles TPJ, Chiti F, Vendruscolo M, Dobson CM.

Nat Commun. 2019 Jan 15;10(1):225. doi: 10.1038/s41467-018-07699-5.

11.

Shear wave elastography of median nerve at wrist and forearm. Heterogeneity of normative values.

Bedewi MA, Coraci D, Ruggeri F, Giovannini S, Gentile L, Padua L.

J Plast Reconstr Aesthet Surg. 2019 Jan;72(1):137-171. doi: 10.1016/j.bjps.2018.09.015. Epub 2018 Nov 13. No abstract available.

PMID:
30467003
12.

Microfluidic deposition for resolving single-molecule protein architecture and heterogeneity.

Ruggeri FS, Charmet J, Kartanas T, Peter Q, Chia S, Habchi J, Dobson CM, Vendruscolo M, Knowles TPJ.

Nat Commun. 2018 Sep 24;9(1):3890. doi: 10.1038/s41467-018-06345-4.

13.

Identification of Oxidative Stress in Red Blood Cells with Nanoscale Chemical Resolution by Infrared Nanospectroscopy.

Ruggeri FS, Marcott C, Dinarelli S, Longo G, Girasole M, Dietler G, Knowles TPJ.

Int J Mol Sci. 2018 Aug 30;19(9). pii: E2582. doi: 10.3390/ijms19092582.

14.

N-terminal Huntingtin (Htt) phosphorylation is a molecular switch regulating Htt aggregation, helical conformation, internalization, and nuclear targeting.

DeGuire SM, Ruggeri FS, Fares MB, Chiki A, Cendrowska U, Dietler G, Lashuel HA.

J Biol Chem. 2018 Nov 30;293(48):18540-18558. doi: 10.1074/jbc.RA118.004621. Epub 2018 Sep 5.

15.

Nanoplasmonic mid-infrared biosensor for in vitro protein secondary structure detection.

Etezadi D, Warner Iv JB, Ruggeri FS, Dietler G, Lashuel HA, Altug H.

Light Sci Appl. 2017 Aug 25;6(8):e17029. doi: 10.1038/lsa.2017.29. eCollection 2017 Aug.

16.

Solution fibre spinning technique for the fabrication of tuneable decellularised matrix-laden fibres and fibrous micromembranes.

Li Z, Tuffin J, Lei IM, Ruggeri FS, Lewis NS, Gill EL, Savin T, Huleihel L, Badylak SF, Knowles T, Satchell SC, Welsh GI, Saleem MA, Huang YYS.

Acta Biomater. 2018 Sep 15;78:111-122. doi: 10.1016/j.actbio.2018.08.010. Epub 2018 Aug 10.

PMID:
30099199
17.

The Lateral Femoral Cutaneous Nerve: Ultrasound Support in Nerve Assessing.

Coraci D, Giovannini S, Loreti C, Ruggeri F, Padua L.

Reg Anesth Pain Med. 2018 Aug;43(6):650-651. doi: 10.1097/AAP.0000000000000830. No abstract available.

PMID:
30036322
18.

Stabilization and Characterization of Cytotoxic Aβ40 Oligomers Isolated from an Aggregation Reaction in the Presence of Zinc Ions.

Mannini B, Habchi J, Chia S, Ruggeri FS, Perni M, Knowles TPJ, Dobson CM, Vendruscolo M.

ACS Chem Neurosci. 2018 Dec 19;9(12):2959-2971. doi: 10.1021/acschemneuro.8b00141. Epub 2018 Aug 10.

PMID:
29986583
19.

Identification and nanomechanical characterization of the fundamental single-strand protofilaments of amyloid α-synuclein fibrils.

Ruggeri FS, Benedetti F, Knowles TPJ, Lashuel HA, Sekatskii S, Dietler G.

Proc Natl Acad Sci U S A. 2018 Jul 10;115(28):7230-7235. doi: 10.1073/pnas.1721220115. Epub 2018 Jun 25.

20.

Determination of Polypeptide Conformation with Nanoscale Resolution in Water.

Ramer G, Ruggeri FS, Levin A, Knowles TPJ, Centrone A.

ACS Nano. 2018 Jul 24;12(7):6612-6619. doi: 10.1021/acsnano.8b01425. Epub 2018 Jun 28.

PMID:
29932670
21.

Cholesterol catalyses Aβ42 aggregation through a heterogeneous nucleation pathway in the presence of lipid membranes.

Habchi J, Chia S, Galvagnion C, Michaels TCT, Bellaiche MMJ, Ruggeri FS, Sanguanini M, Idini I, Kumita JR, Sparr E, Linse S, Dobson CM, Knowles TPJ, Vendruscolo M.

Nat Chem. 2018 Jun;10(6):673-683. doi: 10.1038/s41557-018-0031-x. Epub 2018 May 7.

PMID:
29736006
22.

Entropic Trapping of a Singly Charged Molecule in Solution.

Ruggeri F, Krishnan M.

Nano Lett. 2018 Jun 13;18(6):3773-3779. doi: 10.1021/acs.nanolett.8b01011. Epub 2018 May 2.

PMID:
29688720
23.

FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-π Interactions.

Qamar S, Wang G, Randle SJ, Ruggeri FS, Varela JA, Lin JQ, Phillips EC, Miyashita A, Williams D, Ströhl F, Meadows W, Ferry R, Dardov VJ, Tartaglia GG, Farrer LA, Kaminski Schierle GS, Kaminski CF, Holt CE, Fraser PE, Schmitt-Ulms G, Klenerman D, Knowles T, Vendruscolo M, St George-Hyslop P.

Cell. 2018 Apr 19;173(3):720-734.e15. doi: 10.1016/j.cell.2018.03.056.

24.

Water-Dispersible Polydopamine-Coated Nanofibers for Stimulation of Neuronal Growth and Adhesion.

Sieste S, Mack T, Synatschke CV, Schilling C, Meyer Zu Reckendorf C, Pendi L, Harvey S, Ruggeri FS, Knowles TPJ, Meier C, Ng DYW, Weil T, Knöll B.

Adv Healthc Mater. 2018 Jun;7(11):e1701485. doi: 10.1002/adhm.201701485. Epub 2018 Apr 10.

PMID:
29635761
25.

Spectrally resolved single-molecule electrometry.

Ruggeri F, Krishnan M.

J Chem Phys. 2018 Mar 28;148(12):123307. doi: 10.1063/1.5008936.

PMID:
29604878
26.

Molecular determinants of the interaction of EGCG with ordered and disordered proteins.

Fusco G, Sanz-Hernandez M, Ruggeri FS, Vendruscolo M, Dobson CM, De Simone A.

Biopolymers. 2018 Aug;109(10):e23117. doi: 10.1002/bip.23117. Epub 2018 Mar 30.

PMID:
29603125
27.

Lattice diffusion of a single molecule in solution.

Ruggeri F, Krishnan M.

Phys Rev E. 2017 Dec;96(6-1):062406. doi: 10.1103/PhysRevE.96.062406. Epub 2017 Dec 13.

PMID:
29347432
28.

Pilot survey of norovirus in Northern Italy: an example of surveillance of norovirus gastroenteritis.

Pagani E, Folli F, Tofani S, Ruggeri FM, Ostanello F, Di Bartolo I.

Epidemiol Infect. 2018 Feb;146(3):291-296. doi: 10.1017/S0950268817002989. Epub 2018 Jan 8.

PMID:
29307329
29.

Amyloid single-cell cytotoxicity assays by nanomotion detection.

Ruggeri FS, Mahul-Mellier AL, Kasas S, Lashuel HA, Longo G, Dietler G.

Cell Death Discov. 2017 Aug 21;3:17053. doi: 10.1038/cddiscovery.2017.53. eCollection 2017.

30.

Silk micrococoons for protein stabilisation and molecular encapsulation.

Shimanovich U, Ruggeri FS, De Genst E, Adamcik J, Barros TP, Porter D, Müller T, Mezzenga R, Dobson CM, Vollrath F, Holland C, Knowles TPJ.

Nat Commun. 2017 Jul 19;8:15902. doi: 10.1038/ncomms15902.

31.

Nanobodies raised against monomeric ɑ-synuclein inhibit fibril formation and destabilize toxic oligomeric species.

Iljina M, Hong L, Horrocks MH, Ludtmann MH, Choi ML, Hughes CD, Ruggeri FS, Guilliams T, Buell AK, Lee JE, Gandhi S, Lee SF, Bryant CE, Vendruscolo M, Knowles TPJ, Dobson CM, De Genst E, Klenerman D.

BMC Biol. 2017 Jul 3;15(1):57. doi: 10.1186/s12915-017-0390-6.

32.

Transversus abdominis plane (TAP) block versus thoracic epidural analgesia (TEA) in laparoscopic colon surgery in the ERAS program.

Pirrera B, Alagna V, Lucchi A, Berti P, Gabbianelli C, Martorelli G, Mozzoni L, Ruggeri F, Ingardia A, Nardi G, Garulli G.

Surg Endosc. 2018 Jan;32(1):376-382. doi: 10.1007/s00464-017-5686-7. Epub 2017 Jul 1.

PMID:
28667547
33.

Detection of uncommon G3P[3] rotavirus A (RVA) strain in rat possessing a human RVA-like VP6 and a novel NSP2 genotype.

Ianiro G, Di Bartolo I, De Sabato L, Pampiglione G, Ruggeri FM, Ostanello F.

Infect Genet Evol. 2017 Sep;53:206-211. doi: 10.1016/j.meegid.2017.06.008. Epub 2017 Jun 8.

PMID:
28603021
34.

Hospital-acquired rotavirus and norovirus acute gastroenteritis in a pediatric unit, in 2014-2015.

Valentini D, Ianiro G, Di Bartolo I, Di Camillo C, Boccuzzi E, Vittucci AC, Ruggeri FM, Monini M.

J Med Virol. 2017 Oct;89(10):1768-1774. doi: 10.1002/jmv.24866. Epub 2017 Jul 10.

PMID:
28547892
35.

Group A rotavirus genotypes in hospital-acquired gastroenteritis in Italy, 2012-14.

Ianiro G, Delogu R, Fiore L, Monini M, Ruggeri FM; RotaNet–Italy Study Group.

J Hosp Infect. 2017 Jul;96(3):262-267. doi: 10.1016/j.jhin.2017.04.004. Epub 2017 Apr 8.

PMID:
28446379
36.

Mutant Exon1 Huntingtin Aggregation is Regulated by T3 Phosphorylation-Induced Structural Changes and Crosstalk between T3 Phosphorylation and Acetylation at K6.

Chiki A, DeGuire SM, Ruggeri FS, Sanfelice D, Ansaloni A, Wang ZM, Cendrowska U, Burai R, Vieweg S, Pastore A, Dietler G, Lashuel HA.

Angew Chem Int Ed Engl. 2017 May 2;56(19):5202-5207. doi: 10.1002/anie.201611750. Epub 2017 Mar 23.

PMID:
28334491
37.

Single-molecule electrometry.

Ruggeri F, Zosel F, Mutter N, Różycka M, Wojtas M, Ożyhar A, Schuler B, Krishnan M.

Nat Nanotechnol. 2017 May;12(5):488-495. doi: 10.1038/nnano.2017.26. Epub 2017 Mar 13.

PMID:
28288117
38.

A stochastic model for MRSA transmission within a hospital ward incorporating environmental contamination.

Lee XJ, Fulford GR, Pettitt AN, Ruggeri F.

Epidemiol Infect. 2017 Mar;145(4):825-838. doi: 10.1017/S0950268816002880. Epub 2016 Dec 12.

PMID:
27938427
39.

Retrospective Study Evaluating Seroprevalence of Hepatitis E Virus in Blood Donors and in Swine Veterinarians in Italy (2004).

De Sabato L, Di Bartolo I, Montomoli E, Trombetta C, Ruggeri FM, Ostanello F.

Zoonoses Public Health. 2017 Jun;64(4):308-312. doi: 10.1111/zph.12332. Epub 2016 Dec 2.

PMID:
27911040
40.

Detection of Torque Teno Sus Virus in Pork Bile and Liver Sausages.

Monini M, Vignolo E, Ianiro G, Ostanello F, Ruggeri FM, Di Bartolo I.

Food Environ Virol. 2016 Dec;8(4):283-288. Epub 2016 Jun 13.

PMID:
27294982
41.

A critical concentration of N-terminal pyroglutamylated amyloid beta drives the misfolding of Ab1-42 into more toxic aggregates.

Galante D, Ruggeri FS, Dietler G, Pellistri F, Gatta E, Corsaro A, Florio T, Perico A, D'Arrigo C.

Int J Biochem Cell Biol. 2016 Oct;79:261-270. doi: 10.1016/j.biocel.2016.08.037. Epub 2016 Aug 31.

PMID:
27592450
42.

Nanoscale studies link amyloid maturity with polyglutamine diseases onset.

Ruggeri FS, Vieweg S, Cendrowska U, Longo G, Chiki A, Lashuel HA, Dietler G.

Sci Rep. 2016 Aug 8;6:31155. doi: 10.1038/srep31155.

43.

Molecular characterization of two rare human G8P[14] rotavirus strains, detected in Italy in 2012.

Delogu R, Ianiro G, Morea A, Chironna M, Fiore L, Ruggeri FM.

Infect Genet Evol. 2016 Oct;44:303-312. doi: 10.1016/j.meegid.2016.07.018. Epub 2016 Jul 19.

PMID:
27449953
44.

AFM-Based Single Molecule Techniques: Unraveling the Amyloid Pathogenic Species.

Ruggeri FS, Habchi J, Cerreta A, Dietler G.

Curr Pharm Des. 2016;22(26):3950-70. Review.

45.

Genetic variability of VP7, VP4, VP6 and NSP4 genes of common human G1P[8] rotavirus strains circulating in Italy between 2010 and 2014.

Ianiro G, Delogu R, Fiore L, Ruggeri FM; RotaNet-Italy Study Group.

Virus Res. 2016 Jul 15;220:117-28. doi: 10.1016/j.virusres.2016.04.018. Epub 2016 Apr 26.

PMID:
27130628
46.

Prevalence of Neuropathic Pain in Cancer Patients: Pooled Estimates From a Systematic Review of Published Literature and Results From a Survey Conducted in 50 Italian Palliative Care Centers.

Roberto A, Deandrea S, Greco MT, Corli O, Negri E, Pizzuto M, Ruggeri F.

J Pain Symptom Manage. 2016 Jun;51(6):1091-1102.e4. doi: 10.1016/j.jpainsymman.2015.12.336. Epub 2016 Mar 25. Review.

PMID:
27017920
47.

Group Intensive Cognitive Activation in Patients with Major or Mild Neurocognitive Disorder.

Panerai S, Tasca D, Musso S, Catania V, Ruggeri F, Raggi A, Muratore S, Prestianni G, Bonforte C, Ferri R.

Front Behav Neurosci. 2016 Feb 29;10:34. doi: 10.3389/fnbeh.2016.00034. eCollection 2016.

48.

Serological survey of hepatitis E virus infection in farmed and pet rabbits in Italy.

Di Bartolo I, De Sabato L, Marata A, Martinelli N, Magistrali CF, Monini M, Ponterio E, Ostanello F, Ruggeri FM.

Arch Virol. 2016 May;161(5):1343-6. doi: 10.1007/s00705-016-2778-y. Epub 2016 Feb 12.

PMID:
26873813
49.

Burden of pediatrics hospitalizations associated with Rotavirus gastroenteritis in Lombardy (Northern Italy) before immunization program.

Pellegrinelli L, Bubba L, Primache V, Chiaramonte I, Ruggeri FM, Fiore L, Binda S.

Ann Ist Super Sanita. 2015;51(4):346-51. doi: 10.4415/ANN_15_04_16.

50.

Complete genome sequencing of a genotype 3 hepatitis E virus strain identified in a swine farm in Italy.

Di Bartolo I, Angeloni G, Monini M, Maione E, Marrone R, Ostanello F, Ruggeri FM.

Virus Res. 2016 Jan 4;211:89-95. doi: 10.1016/j.virusres.2015.09.014. Epub 2015 Sep 28.

PMID:
26415753

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