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Items: 26


Positive follow-up blood cultures identify high mortality risk among patients with Gram-negative bacteraemia.

Maskarinec SA, Park LP, Ruffin F, Turner NA, Patel N, Eichenberger EM, van Duin D, Lodise T, Fowler VG Jr, Thaden JT.

Clin Microbiol Infect. 2020 Feb 28. pii: S1198-743X(20)30050-1. doi: 10.1016/j.cmi.2020.01.025. [Epub ahead of print]


Risk stratification biomarkers for Staphylococcus aureus bacteraemia.

Cao Y, Guimaraes AO, Peck MC, Mayba O, Ruffin F, Hong K, Carrasco-Triguero M, Fowler VG Jr, Maskarinec SA, Rosenberger CM.

Clin Transl Immunology. 2020 Feb 13;9(2):e1110. doi: 10.1002/cti2.1110. eCollection 2020.


Genetic variation of DNA methyltransferase-3A contributes to protection against persistent MRSA bacteremia in patients.

Mba Medie F, Sharma-Kuinkel BK, Ruffin F, Chan LC, Rossetti M, Chang YL, Park LP, Bayer AS, Filler SG, Ahn R, Reed EF, Gjertson D, Yeaman MR, Fowler VG Jr; MRSA Systems Immunobiology Group.

Proc Natl Acad Sci U S A. 2019 Oct 1;116(40):20087-20096. doi: 10.1073/pnas.1909849116. Epub 2019 Sep 16.


Associations of pathogen-specific and host-specific characteristics with disease outcome in patients with Staphylococcus aureus bacteremic pneumonia.

Sharma-Kuinkel BK, Tkaczyk C, Bonnell J, Yu L, Tovchigrechko A, Tabor DE, Park LP, Ruffin F, Esser MT, Sellman BR, Fowler VG Jr, Ruzin A.

Clin Transl Immunology. 2019 Jul 19;8(7):e01070. doi: 10.1002/cti2.1070. eCollection 2019.


Prognostic Power of Pathogen Cell-Free DNA in Staphylococcus aureus Bacteremia.

Guimaraes AO, Gutierrez J, Maskarinec SA, Cao Y, Hong K, Ruffin F, Carrasco-Triguero M, Peck MC, Fowler VG, Baruch A, Rosenberger CM.

Open Forum Infect Dis. 2019 Mar 15;6(4):ofz126. doi: 10.1093/ofid/ofz126. eCollection 2019 Apr.


Changing Characteristics of Staphylococcus aureus Bacteremia: Results From a 21-Year, Prospective, Longitudinal Study.

Souli M, Ruffin F, Choi SH, Park LP, Gao S, Lent NC, Sharma-Kuinkel BK, Thaden JT, Maskarinec SA, Wanda L, Hill-Rorie J, Warren B, Hansen B, Fowler VG.

Clin Infect Dis. 2019 Nov 13;69(11):1868-1877. doi: 10.1093/cid/ciz112.


Human genetic variation in GLS2 is associated with development of complicated Staphylococcus aureus bacteremia.

Scott WK, Medie FM, Ruffin F, Sharma-Kuinkel BK, Cyr DD, Guo S, Dykxhoorn DM, Skov RL, Bruun NE, Dahl A, Lerche CJ, Petersen A, Larsen AR, Lauridsen TK, Johansen HK, Ullum H, Sørensen E, Hassager C, Bundgaard H, Schønheyder HC, Torp-Pedersen C, Østergaard LB, Arpi M, Rosenvinge F, Erikstrup LT, Chehri M, Søgaard P, Andersen PS, Fowler VG Jr.

PLoS Genet. 2018 Oct 5;14(10):e1007667. doi: 10.1371/journal.pgen.1007667. eCollection 2018 Oct.


A Prognostic Model of Persistent Bacteremia and Mortality in Complicated Staphylococcus aureus Bloodstream Infection.

Guimaraes AO, Cao Y, Hong K, Mayba O, Peck MC, Gutierrez J, Ruffin F, Carrasco-Triguero M, Dinoso JB, Clemenzi-Allen A, Koss CA, Maskarinec SA, Chambers HF, Fowler VG, Baruch A, Rosenberger CM.

Clin Infect Dis. 2019 Apr 24;68(9):1502-1511. doi: 10.1093/cid/ciy739.


The Risk of Cardiac Device-Related Infection in Bacteremic Patients Is Species Specific: Results of a 12-Year Prospective Cohort.

Maskarinec SA, Thaden JT, Cyr DD, Ruffin F, Souli M, Fowler VG.

Open Forum Infect Dis. 2017 Jun 21;4(3):ofx132. doi: 10.1093/ofid/ofx132. eCollection 2017 Summer.


Geographic Expansion of Lyme Disease in Michigan, 2000-2014.

Lantos PM, Tsao J, Nigrovic LE, Auwaerter PG, Fowler VG, Ruffin F, Foster E, Hickling G.

Open Forum Infect Dis. 2017 Jan 9;4(1):ofw269. doi: 10.1093/ofid/ofw269. eCollection 2017 Winter.


Results from a 13-Year Prospective Cohort Study Show Increased Mortality Associated with Bloodstream Infections Caused by Pseudomonas aeruginosa Compared to Other Bacteria.

Thaden JT, Park LP, Maskarinec SA, Ruffin F, Fowler VG Jr, van Duin D.

Antimicrob Agents Chemother. 2017 May 24;61(6). pii: e02671-16. doi: 10.1128/AAC.02671-16. Print 2017 Jun.


Evaluating genetic susceptibility to Staphylococcus aureus bacteremia in African Americans using admixture mapping.

Cyr DD, Allen AS, Du GJ, Ruffin F, Adams C, Thaden JT, Maskarinec SA, Souli M, Guo S, Dykxhoorn DM, Scott WK, Fowler VG Jr.

Genes Immun. 2017 Mar;18(2):95-99. doi: 10.1038/gene.2017.6. Epub 2017 Mar 23.


Increased Costs Associated with Bloodstream Infections Caused by Multidrug-Resistant Gram-Negative Bacteria Are Due Primarily to Patients with Hospital-Acquired Infections.

Thaden JT, Li Y, Ruffin F, Maskarinec SA, Hill-Rorie JM, Wanda LC, Reed SD, Fowler VG Jr.

Antimicrob Agents Chemother. 2017 Feb 23;61(3). pii: e01709-16. doi: 10.1128/AAC.01709-16. Print 2017 Mar.


Diagnosis of Capnocytophaga canimorsus Sepsis by Whole-Genome Next-Generation Sequencing.

Abril MK, Barnett AS, Wegermann K, Fountain E, Strand A, Heyman BM, Blough BA, Swaminathan AC, Sharma-Kuinkel B, Ruffin F, Alexander BD, McCall CM, Costa SF, Arcasoy MO, Hong DK, Blauwkamp TA, Kertesz M, Fowler VG Jr, Kraft BD.

Open Forum Infect Dis. 2016 Jul 12;3(3):ofw144. eCollection 2016 Sep.


Application of Whole-Genome Sequencing to an Unusual Outbreak of Invasive Group A Streptococcal Disease.

Galloway-Peña J, Clement ME, Sharma Kuinkel BK, Ruffin F, Flores AR, Levinson H, Shelburne SA, Moore Z, Fowler VG Jr.

Open Forum Infect Dis. 2016 Feb 19;3(1):ofw042. doi: 10.1093/ofid/ofw042. eCollection 2016 Jan.


Increased in vitro phenol-soluble modulin production is associated with soft tissue infection source in clinical isolates of methicillin-susceptible Staphylococcus aureus.

Qi R, Joo HS, Sharma-Kuinkel B, Berlon NR, Park L, Fu CL, Messina JA, Thaden JT, Yan Q, Ruffin F, Maskarinec S, Warren B, Chu VH, Fortes CQ, Giannitsioti E, Durante-Mangoni E, Kanafani ZA, Otto M, Fowler VG Jr.

J Infect. 2016 Mar;72(3):302-8. doi: 10.1016/j.jinf.2015.11.002. Epub 2016 Jan 9.


Polymorphisms in Fibronectin Binding Proteins A and B among Staphylococcus aureus Bloodstream Isolates Are Not Associated with Arthroplasty Infection.

Eichenberger EM, Thaden JT, Sharma-Kuinkel B, Park LP, Rude TH, Ruffin F, Hos NJ, Seifert H, Rieg S, Kern WV, Lower SK, Fowler VG Jr, Kaasch AJ.

PLoS One. 2015 Nov 25;10(11):e0141436. doi: 10.1371/journal.pone.0141436. eCollection 2015.


Geographic Expansion of Lyme Disease in the Southeastern United States, 2000-2014.

Lantos PM, Nigrovic LE, Auwaerter PG, Fowler VG Jr, Ruffin F, Brinkerhoff RJ, Reber J, Williams C, Broyhill J, Pan WK, Gaines DN.

Open Forum Infect Dis. 2015 Sep 27;2(4):ofv143. doi: 10.1093/ofid/ofv143. eCollection 2015 Dec.


Poor Positive Predictive Value of Lyme Disease Serologic Testing in an Area of Low Disease Incidence.

Lantos PM, Branda JA, Boggan JC, Chudgar SM, Wilson EA, Ruffin F, Fowler V, Auwaerter PG, Nigrovic LE.

Clin Infect Dis. 2015 Nov 1;61(9):1374-80. doi: 10.1093/cid/civ584. Epub 2015 Jul 20.


Characterization of alpha-toxin hla gene variants, alpha-toxin expression levels, and levels of antibody to alpha-toxin in hemodialysis and postsurgical patients with Staphylococcus aureus bacteremia.

Sharma-Kuinkel BK, Wu Y, Tabor DE, Mok H, Sellman BR, Jenkins A, Yu L, Jafri HS, Rude TH, Ruffin F, Schell WA, Park LP, Yan Q, Thaden JT, Messina JA, Fowler VG Jr, Esser MT.

J Clin Microbiol. 2015 Jan;53(1):227-36. doi: 10.1128/JCM.02023-14. Epub 2014 Nov 12.


Staphylococcus aureus bacteremia at 5 US academic medical centers, 2008-2011: significant geographic variation in community-onset infections.

David MZ, Daum RS, Bayer AS, Chambers HF, Fowler VG Jr, Miller LG, Ostrowsky B, Baesa A, Boyle-Vavra S, Eells SJ, Garcia-Houchins S, Gialanella P, Macias-Gil R, Rude TH, Ruffin F, Sieth JJ, Volinski J, Spellberg B.

Clin Infect Dis. 2014 Sep 15;59(6):798-807. doi: 10.1093/cid/ciu410. Epub 2014 May 30.


A genome-wide association study of variants associated with acquisition of Staphylococcus aureus bacteremia in a healthcare setting.

Nelson CL, Pelak K, Podgoreanu MV, Ahn SH, Scott WK, Allen AS, Cowell LG, Rude TH, Zhang Y, Tong A, Ruffin F, Sharma-Kuinkel BK, Fowler VG Jr.

BMC Infect Dis. 2014 Feb 13;14:83. doi: 10.1186/1471-2334-14-83.


Panton-Valentine leukocidin is not the primary determinant of outcome for Staphylococcus aureus skin infections: evaluation from the CANVAS studies.

Tong A, Tong SY, Zhang Y, Lamlertthon S, Sharma-Kuinkel BK, Rude T, Ahn SH, Ruffin F, Llorens L, Tamarana G, Biek D, Critchley I, Fowler VG Jr.

PLoS One. 2012;7(5):e37212. doi: 10.1371/journal.pone.0037212. Epub 2012 May 18.


Presence of genes encoding panton-valentine leukocidin is not the primary determinant of outcome in patients with hospital-acquired pneumonia due to Staphylococcus aureus.

Sharma-Kuinkel BK, Ahn SH, Rude TH, Zhang Y, Tong SY, Ruffin F, Genter FC, Braughton KR, Deleo FR, Barriere SL, Fowler VG Jr.

J Clin Microbiol. 2012 Mar;50(3):848-56. doi: 10.1128/JCM.06219-11. Epub 2012 Jan 11.


Transmission of MRSA between companion animals and infected human patients presenting to outpatient medical care facilities.

Ferreira JP, Anderson KL, Correa MT, Lyman R, Ruffin F, Reller LB, Fowler VG Jr.

PLoS One. 2011;6(11):e26978. doi: 10.1371/journal.pone.0026978. Epub 2011 Nov 10.


Transmission of methicillin-resistant Staphylococcus aureus between human and hamster.

Ferreira JP, Fowler VG Jr, Correa MT, Lyman R, Ruffin F, Anderson KL.

J Clin Microbiol. 2011 Apr;49(4):1679-80. doi: 10.1128/JCM.02469-10. Epub 2011 Feb 16.

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