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Items: 16

1.

Silica cloaking of adenovirus enhances gene delivery while reducing immunogenicity.

Sapre AA, Yong G, Yeh YS, Ruff LE, Plaut JS, Sayar Z, Agarwal A, Martinez J, Nguyen TN, Liu YT, Messmer BT, Esener SC, Fischer JM.

J Control Release. 2019 Mar 10;297:48-59. doi: 10.1016/j.jconrel.2019.01.034. Epub 2019 Jan 25.

PMID:
30690106
2.

Identification of Peptide Mimotope Ligands for Natalizumab.

Ruff LE, Pfeilsticker JA, Johnsen NE, Nocchi S, Messmer BT.

Sci Rep. 2018 Sep 27;8(1):14473. doi: 10.1038/s41598-018-32832-1.

3.

Individualized Dosing of Therapeutic Monoclonal Antibodies-a Changing Treatment Paradigm?

Strik AS, Wang YC, Ruff LE, Yashar W, Messmer BT, Mould DR.

AAPS J. 2018 Sep 5;20(6):99. doi: 10.1208/s12248-018-0257-y.

PMID:
30187153
4.

Molecular and Spectroscopic Characterization of Aspergillus flavipes and Pseudomonas putida L-Methionine γ-Lyase in Vitro.

El-Sayed AS, Ruff LE, Ghany SE, Ali GS, Esener S.

Appl Biochem Biotechnol. 2017 Apr;181(4):1513-1532. doi: 10.1007/s12010-016-2299-x. Epub 2016 Oct 29.

PMID:
27796875
5.

Selection of DNA nanoparticles with preferential binding to aggregated protein target.

Ruff LE, Sapre AA, Plaut JS, De Maere E, Mortier C, Nguyen V, Separa K, Vandenbogaerde S, Vandewalle L, Esener SC, Messmer BT.

Nucleic Acids Res. 2016 Jun 2;44(10):e96. doi: 10.1093/nar/gkw136. Epub 2016 Mar 11.

6.

Antigen-loaded pH-sensitive hydrogel microparticles are taken up by dendritic cells with no requirement for targeting antibodies.

Ruff LE, Mahmoud EA, Sankaranarayanan J, Morachis JM, Katayama CD, Corr M, Hedrick SM, Almutairi A.

Integr Biol (Camb). 2013 Jan;5(1):195-203. doi: 10.1039/c2ib20109g.

7.

Multivalent porous silicon nanoparticles enhance the immune activation potency of agonistic CD40 antibody.

Gu L, Ruff LE, Qin Z, Corr M, Hedrick SM, Sailor MJ.

Adv Mater. 2012 Aug 2;24(29):3981-7. doi: 10.1002/adma.201200776. Epub 2012 Jun 12.

8.

HLA B*5701-positive long-term nonprogressors/elite controllers are not distinguished from progressors by the clonal composition of HIV-specific CD8+ T cells.

Mendoza D, Royce C, Ruff LE, Ambrozak DR, Quigley MF, Dang T, Venturi V, Price DA, Douek DC, Migueles SA, Connors M.

J Virol. 2012 Apr;86(7):4014-8. doi: 10.1128/JVI.06982-11. Epub 2012 Jan 25.

9.

High-functional-avidity cytotoxic T lymphocyte responses to HLA-B-restricted Gag-derived epitopes associated with relative HIV control.

Berger CT, Frahm N, Price DA, Mothe B, Ghebremichael M, Hartman KL, Henry LM, Brenchley JM, Ruff LE, Venturi V, Pereyra F, Sidney J, Sette A, Douek DC, Walker BD, Kaufmann DE, Brander C.

J Virol. 2011 Sep;85(18):9334-45. doi: 10.1128/JVI.00460-11. Epub 2011 Jul 13.

10.

Acquisition of direct antiviral effector functions by CMV-specific CD4+ T lymphocytes with cellular maturation.

Casazza JP, Betts MR, Price DA, Precopio ML, Ruff LE, Brenchley JM, Hill BJ, Roederer M, Douek DC, Koup RA.

J Exp Med. 2006 Dec 25;203(13):2865-77. Epub 2006 Dec 11.

11.

Preferential infection shortens the life span of human immunodeficiency virus-specific CD4+ T cells in vivo.

Brenchley JM, Ruff LE, Casazza JP, Koup RA, Price DA, Douek DC.

J Virol. 2006 Jul;80(14):6801-9.

12.

Avidity for antigen shapes clonal dominance in CD8+ T cell populations specific for persistent DNA viruses.

Price DA, Brenchley JM, Ruff LE, Betts MR, Hill BJ, Roederer M, Koup RA, Migueles SA, Gostick E, Wooldridge L, Sewell AK, Connors M, Douek DC.

J Exp Med. 2005 Nov 21;202(10):1349-61. Epub 2005 Nov 14.

13.

T cell receptor recognition motifs govern immune escape patterns in acute SIV infection.

Price DA, West SM, Betts MR, Ruff LE, Brenchley JM, Ambrozak DR, Edghill-Smith Y, Kuroda MJ, Bogdan D, Kunstman K, Letvin NL, Franchini G, Wolinsky SM, Koup RA, Douek DC.

Immunity. 2004 Dec;21(6):793-803.

14.

CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract.

Brenchley JM, Schacker TW, Ruff LE, Price DA, Taylor JH, Beilman GJ, Nguyen PL, Khoruts A, Larson M, Haase AT, Douek DC.

J Exp Med. 2004 Sep 20;200(6):749-59. Epub 2004 Sep 13.

15.

Definitive separation of graft-versus-leukemia- and graft-versus-host-specific CD4+ T cells by virtue of their receptor beta loci sequences.

Michalek J, Collins RH, Durrani HP, Vaclavkova P, Ruff LE, Douek DC, Vitetta ES.

Proc Natl Acad Sci U S A. 2003 Feb 4;100(3):1180-4. Epub 2003 Jan 16.

16.

Beta 1-integrins regulate the formation and adhesion of ovarian carcinoma multicellular spheroids.

Casey RC, Burleson KM, Skubitz KM, Pambuccian SE, Oegema TR Jr, Ruff LE, Skubitz AP.

Am J Pathol. 2001 Dec;159(6):2071-80.

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