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Items: 1 to 50 of 124

1.

mir-124-5p Regulates Phagocytosis of Human Macrophages by Targeting the Actin Cytoskeleton via the ARP2/3 Complex.

Herdoiza Padilla E, Crauwels P, Bergner T, Wiederspohn N, Förstner S, Rinas R, Ruf A, Kleemann M, Handrick R, Tuckermann J, Otte K, Walther P, Riedel CU.

Front Immunol. 2019 Oct 4;10:2210. doi: 10.3389/fimmu.2019.02210. eCollection 2019.

2.

Data-Driven UPLC-Orbitrap MS Analysis in Astrochemistry.

Ruf A, Poinot P, Geffroy C, Le Sergeant d'Hendecourt L, Danger G.

Life (Basel). 2019 May 2;9(2). pii: E35. doi: 10.3390/life9020035.

3.

The chemodiversity of algal dissolved organic matter from lysed Microcystis aeruginosa cells and its ability to form disinfection by-products during chlorination.

Gonsior M, Powers LC, Williams E, Place A, Chen F, Ruf A, Hertkorn N, Schmitt-Kopplin P.

Water Res. 2019 May 15;155:300-309. doi: 10.1016/j.watres.2019.02.030. Epub 2019 Feb 27.

4.

Comparison of Volumetric and Bead-Based Counting of CD34 Cells by Single-Platform Flow Cytometry.

Saraiva L, Wang L, Kammel M, Kummrow A, Atkinson E, Lee JY, Yalcinkaya B, Akgöz M, Höckner J, Ruf A, Engel A, Zhang YZ, O'Shea O, Sassi MP, Divieto C, Lekishvili T, Campbell J, Liu Y, Wang J, Stebbings R, Gaigalas AK, Rigsby P, Neukammer J, Vessillier S.

Cytometry B Clin Cytom. 2019 Feb 20. doi: 10.1002/cyto.b.21773. [Epub ahead of print]

PMID:
30790450
5.

From research to clinic: A sensor reduction method for high-density EEG neurofeedback systems.

Pal P, Theisen DL, Datko M, van Lutterveld R, Roy A, Ruf A, Brewer JA.

Clin Neurophysiol. 2019 Mar;130(3):352-358. doi: 10.1016/j.clinph.2018.11.023. Epub 2018 Dec 16.

PMID:
30669011
6.

Unresolved issues in the prophylaxis of bacterial infections in patients with cirrhosis.

Dirchwolf M, Marciano S, Martínez J, Ruf AE.

World J Hepatol. 2018 Dec 27;10(12):892-897. doi: 10.4254/wjh.v10.i12.892.

7.

Can Mindfulness Address Maladaptive Eating Behaviors? Why Traditional Diet Plans Fail and How New Mechanistic Insights May Lead to Novel Interventions.

Brewer JA, Ruf A, Beccia AL, Essien GI, Finn LM, van Lutterveld R, Mason AE.

Front Psychol. 2018 Sep 10;9:1418. doi: 10.3389/fpsyg.2018.01418. eCollection 2018.

8.

Data-Driven Astrochemistry: One Step Further within the Origin of Life Puzzle.

Ruf A, d'Hendecourt LLS, Schmitt-Kopplin P.

Life (Basel). 2018 Jun 1;8(2). pii: E18. doi: 10.3390/life8020018. Review.

9.

Domain swap in the C-terminal ubiquitin-like domain of human doublecortin.

Rufer AC, Kusznir E, Burger D, Stihle M, Ruf A, Rudolph MG.

Acta Crystallogr D Struct Biol. 2018 May 1;74(Pt 5):450-462. doi: 10.1107/S2059798318004813. Epub 2018 Apr 26.

PMID:
29717716
10.

Do dihydroxymagnesium carboxylates form Grignard-type reagents? A theoretical investigation on decarboxylative fragmentation.

Ruf A, Kanawati B, Schmitt-Kopplin P.

J Mol Model. 2018 Mar 27;24(4):106. doi: 10.1007/s00894-018-3639-2.

PMID:
29589173
11.

Trends in liver transplantation for hepatitis C in a country with reduced access to direct-acting antiviral agents.

Dirchwolf M, Marciano S, Giunta DH, Posadas-Martínez ML, Biggins SW, Ruf AE.

Clin Transplant. 2018 Apr;32(4):e13230. doi: 10.1111/ctr.13230. Epub 2018 Mar 23.

PMID:
29485711
12.

Mapping complex mind states: EEG neural substrates of meditative unified compassionate awareness.

Schoenberg PLA, Ruf A, Churchill J, Brown DP, Brewer JA.

Conscious Cogn. 2018 Jan;57:41-53. doi: 10.1016/j.concog.2017.11.003. Epub 2017 Nov 21.

PMID:
29169033
13.

Three-Dimensional Imaging of Biological Tissue by Cryo X-Ray Ptychography.

Shahmoradian SH, Tsai EHR, Diaz A, Guizar-Sicairos M, Raabe J, Spycher L, Britschgi M, Ruf A, Stahlberg H, Holler M.

Sci Rep. 2017 Jul 24;7(1):6291. doi: 10.1038/s41598-017-05587-4.

14.

Singlet Fission in Weakly Interacting Acene Molecules.

Izadnia S, Schönleber DW, Eisfeld A, Ruf A, LaForge AC, Stienkemeier F.

J Phys Chem Lett. 2017 May 4;8(9):2068-2073. doi: 10.1021/acs.jpclett.7b00319. Epub 2017 Apr 25.

PMID:
28421765
15.

Ombitasvir/paritaprevir/ritonavir/dasabuvir ± ribavirin is safe and effective in HCV-infected patients in a real-life cohort from Latin America.

Mendizabal M, Haddad L, Gallardo PE, Ferrada A, Soza AA, Adrover R, Aravena E, Roblero JP, Prieto J, Vujacich C, Romero G, Muñoz A, Anders M, Hernández N, Coccozella D, Gruz F, Reggiardo MV, Ruf AE, Varón A, Cartier M, Pérez Ravier R, Ridruejo E, Peralta M, Poncino D, Vorobioff J, Aballay Soteras G, Silva MO.

J Med Virol. 2017 Sep;89(9):1590-1596. doi: 10.1002/jmv.24816. Epub 2017 Jun 6.

PMID:
28370222
16.

Previously unknown class of metalorganic compounds revealed in meteorites.

Ruf A, Kanawati B, Hertkorn N, Yin QZ, Moritz F, Harir M, Lucio M, Michalke B, Wimpenny J, Shilobreeva S, Bronsky B, Saraykin V, Gabelica Z, Gougeon RD, Quirico E, Ralew S, Jakubowski T, Haack H, Gonsior M, Jenniskens P, Hinman NW, Schmitt-Kopplin P.

Proc Natl Acad Sci U S A. 2017 Mar 14;114(11):2819-2824. doi: 10.1073/pnas.1616019114. Epub 2017 Feb 27.

17.

Quadruple space-group ambiguity owing to rotational and translational noncrystallographic symmetry in human liver fructose-1,6-bisphosphatase.

Ruf A, Tetaz T, Schott B, Joseph C, Rudolph MG.

Acta Crystallogr D Struct Biol. 2016 Nov 1;72(Pt 11):1212-1224. Epub 2016 Oct 28.

18.

Clinical epidemiology of acute hepatitis C in South America.

Dirchwolf M, Marciano S, Mauro E, Ruf AE, Rezzonico L, Anders M, Chiodi D, Petta NG, Borzi S, Tanno F, Ridruejo E, Barreyro F, Shulman C, Plaza P, Carbonetti R, Tadey L, Schroder T, Fainboim H.

J Med Virol. 2017 Feb;89(2):276-283. doi: 10.1002/jmv.24588. Epub 2016 Oct 21.

PMID:
27253181
19.

Revising metrics for aggressiveness assessment in liver transplantation centers.

Ruf AE, Dirchwolf M, Biggins SW, Villamil FG.

J Hepatol. 2016 Nov;65(5):1066-1067. doi: 10.1016/j.jhep.2016.06.033. Epub 2016 Jul 28. No abstract available.

PMID:
27476766
20.

Crystal Structures of the Human Doublecortin C- and N-terminal Domains in Complex with Specific Antibodies.

Burger D, Stihle M, Sharma A, Di Lello P, Benz J, D'Arcy B, Debulpaep M, Fry D, Huber W, Kremer T, Laeremans T, Matile H, Ross A, Rufer AC, Schoch G, Steinmetz MO, Steyaert J, Rudolph MG, Thoma R, Ruf A.

J Biol Chem. 2016 Jul 29;291(31):16292-306. doi: 10.1074/jbc.M116.726547. Epub 2016 May 10.

21.

Consensus, Dilemmas, and Challenges in Living Donor Liver Transplantation in Latin America.

Salvalaggio PR, Seda Neto J, Alves JA, Fonseca EA, Carneiro de Albuquerque L, Andraus W, Massarollo PB, Duro Garcia V, Maurette RJ, Ruf AE, Pacheco-Moreira LF, Caicedo Rusca LA, Osorio VB, Matamoros MA, Varela-Fascinetto G, Jarufe NP.

Transplantation. 2016 Jun;100(6):1161-4. doi: 10.1097/TP.0000000000001180. Review.

PMID:
27203583
22.

Challenges and Rewards in Medicinal Chemistry Targeting Cardiovascular and Metabolic Diseases.

Neidhart W, Ackermann J, Amrein K, Conte A, Hunziker D, Kuhn B, Märki HP, Nettekoven M, Ruf A, Schulz-Gasch T, Mayweg AV.

Chimia (Aarau). 2015;69(7-8):407-13. doi: 10.2533/chimia.2015.407. Review.

PMID:
26507592
23.

Combinational Effect of CYP3A5 and MDR-1 Polymorphisms on Tacrolimus Pharmacokinetics in Liver Transplant Patients.

Buendía JA, Otamendi E, Kravetz MC, Cairo F, Ruf A, de Davila M, Powazniak Y, Nafissi J, Lazarowski A, Bramuglia G, Villamil F.

Exp Clin Transplant. 2015 Oct;13(5):441-8.

24.

Challenges and Rewards in Medicinal Chemistry Targeting Cardiovascular and Metabolic Diseases.

Neidhart W, Ackermann J, Amrein K, Conte A, Hunziker D, Kuhn B, Märki HP, Nettekoven M, Ruf A, Schulz-Gasch T, Mayweg AV.

Chimia (Aarau). 2015 Aug 19;69(7):407-413. doi: 10.2533/chimia.2015.407.

PMID:
28482972
25.

Role of systemic inflammation in cirrhosis: From pathogenesis to prognosis.

Dirchwolf M, Ruf AE.

World J Hepatol. 2015 Aug 8;7(16):1974-81. doi: 10.4254/wjh.v7.i16.1974.

26.

C-reactive protein and model for end-stage liver disease score: Have we found the fifth element?

Ruf AE, Villamil FG.

Liver Transpl. 2015 Jun;21(6):713-5. doi: 10.1002/lt.24140. Epub 2015 May 9. No abstract available.

27.

Elucidation of direct competition and allosteric modulation of small-molecular-weight protein ligands using surface plasmon resonance methods.

Huber W, Sinopoli A, Kohler J, Hug M, Ruf A, Huber S.

J Mol Recognit. 2015 Aug;28(8):480-91. doi: 10.1002/jmr.2465. Epub 2015 Mar 12.

PMID:
25763559
28.

Real-time monitoring of binding events on a thermostabilized human A2A receptor embedded in a lipid bilayer by surface plasmon resonance.

Bocquet N, Kohler J, Hug MN, Kusznir EA, Rufer AC, Dawson RJ, Hennig M, Ruf A, Huber W, Huber S.

Biochim Biophys Acta. 2015 May;1848(5):1224-33. doi: 10.1016/j.bbamem.2015.02.014. Epub 2015 Feb 25.

29.

Donor selection criteria for liver transplantation in Argentina: are current standards too rigorous?

Dirchwolf M, Ruf AE, Biggins SW, Bisigniano L, Hansen Krogh D, Villamil FG.

Transpl Int. 2015 Feb;28(2):206-13. doi: 10.1111/tri.12489. Epub 2014 Dec 4.

30.

Liver transplantation in Latin America: the state-of-the-art and future trends.

Salvalaggio PR, Caicedo JC, de Albuquerque LC, Contreras A, Garcia VD, Felga GE, Maurette RJ, Medina-Pestana JO, Niño-Murcia A, Pacheco-Moreira LF, Rocca J, Rodriguez-Davalos M, Ruf A, Rusca LA, Vilatoba M.

Transplantation. 2014 Aug 15;98(3):241-6. doi: 10.1097/TP.0000000000000198.

PMID:
25093292
31.

Reducing necrotizing enterocolitis in very low birth weight infants using quality-improvement methods.

Patel AL, Trivedi S, Bhandari NP, Ruf A, Scala CM, Witowitch G, Chen Y, Renschen C, Meier PP, Silvestri JM.

J Perinatol. 2014 Nov;34(11):850-7. doi: 10.1038/jp.2014.123. Epub 2014 Jul 10.

32.

A general protocol for the generation of Nanobodies for structural biology.

Pardon E, Laeremans T, Triest S, Rasmussen SG, Wohlkönig A, Ruf A, Muyldermans S, Hol WG, Kobilka BK, Steyaert J.

Nat Protoc. 2014 Mar;9(3):674-93. doi: 10.1038/nprot.2014.039. Epub 2014 Feb 27.

33.

Indirect absorption spectroscopy using quantum cascade lasers: mid-infrared refractometry and photothermal spectroscopy.

Pfeifer M, Ruf A, Fischer P.

Opt Express. 2013 Nov 4;21(22):25643-54. doi: 10.1364/OE.21.025643.

PMID:
24216789
34.

Determination of protein-ligand binding constants of a cooperatively regulated tetrameric enzyme using electrospray mass spectrometry.

Cubrilovic D, Haap W, Barylyuk K, Ruf A, Badertscher M, Gubler M, Tetaz T, Joseph C, Benz J, Zenobi R.

ACS Chem Biol. 2014 Jan 17;9(1):218-26. doi: 10.1021/cb4007002. Epub 2013 Nov 6.

PMID:
24128068
35.

Mapping the conformational space accessible to BACE2 using surface mutants and cocrystals with Fab fragments, Fynomers and Xaperones.

Banner DW, Gsell B, Benz J, Bertschinger J, Burger D, Brack S, Cuppuleri S, Debulpaep M, Gast A, Grabulovski D, Hennig M, Hilpert H, Huber W, Kuglstatter A, Kusznir E, Laeremans T, Matile H, Miscenic C, Rufer AC, Schlatter D, Steyaert J, Stihle M, Thoma R, Weber M, Ruf A.

Acta Crystallogr D Biol Crystallogr. 2013 Jun;69(Pt 6):1124-37. doi: 10.1107/S0907444913006574. Epub 2013 May 15.

PMID:
23695257
36.

Structure of gentlyase, the neutral metalloprotease of Paenibacillus polymyxa.

Ruf A, Stihle M, Benz J, Schmidt M, Sobek H.

Acta Crystallogr D Biol Crystallogr. 2013 Jan;69(Pt 1):24-31. doi: 10.1107/S0907444912041169. Epub 2012 Dec 20.

37.

Structure of the acid-sensing ion channel 1 in complex with the gating modifier Psalmotoxin 1.

Dawson RJ, Benz J, Stohler P, Tetaz T, Joseph C, Huber S, Schmid G, Hügin D, Pflimlin P, Trube G, Rudolph MG, Hennig M, Ruf A.

Nat Commun. 2012 Jul 3;3:936. doi: 10.1038/ncomms1917.

PMID:
22760635
38.

A novel 506kb deletion causing εγδβ thalassemia.

Rooks H, Clark B, Best S, Rushton P, Oakley M, Thein OS, Cuthbert AC, Britland A, Ruf A, Thein SL.

Blood Cells Mol Dis. 2012 Oct 15-Dec 15;49(3-4):121-7. doi: 10.1016/j.bcmd.2012.05.010. Epub 2012 Jun 5.

PMID:
22677107
39.

Comparative molecular profiling of the PPARα/γ activator aleglitazar: PPAR selectivity, activity and interaction with cofactors.

Dietz M, Mohr P, Kuhn B, Maerki HP, Hartman P, Ruf A, Benz J, Grether U, Wright MB.

ChemMedChem. 2012 Jun;7(6):1101-11. doi: 10.1002/cmdc.201100598. Epub 2012 Apr 4.

40.
41.

Combining biophysical screening and X-ray crystallography for fragment-based drug discovery.

Hennig M, Ruf A, Huber W.

Top Curr Chem. 2012;317:115-43. doi: 10.1007/128_2011_225. Review.

PMID:
21837555
42.

Unique carbohydrate-carbohydrate interactions are required for high affinity binding between FcgammaRIII and antibodies lacking core fucose.

Ferrara C, Grau S, Jäger C, Sondermann P, Brünker P, Waldhauer I, Hennig M, Ruf A, Rufer AC, Stihle M, Umaña P, Benz J.

Proc Natl Acad Sci U S A. 2011 Aug 2;108(31):12669-74. doi: 10.1073/pnas.1108455108. Epub 2011 Jul 18.

43.

Orally active aminopyridines as inhibitors of tetrameric fructose-1,6-bisphosphatase.

Hebeisen P, Haap W, Kuhn B, Mohr P, Wessel HP, Zutter U, Kirchner S, Ruf A, Benz J, Joseph C, Alvarez-Sánchez R, Gubler M, Schott B, Benardeau A, Tozzo E, Kitas E.

Bioorg Med Chem Lett. 2011 Jun 1;21(11):3237-42. doi: 10.1016/j.bmcl.2011.04.044. Epub 2011 Apr 20.

PMID:
21550236
44.

Coagulation status in patients with coronary artery disease taking 100 mg aspirin and healthy volunteers using PFA-100® and ROTEM®.

Feuring M, Wehling M, Ruf A, Burkhardt H, Schultz A.

Int J Clin Pharmacol Ther. 2011 May;49(5):328-35.

PMID:
21543036
45.

Enhancing the stability and solubility of the glucocorticoid receptor ligand-binding domain by high-throughput library screening.

Seitz T, Thoma R, Schoch GA, Stihle M, Benz J, D'Arcy B, Wiget A, Ruf A, Hennig M, Sterner R.

J Mol Biol. 2010 Nov 5;403(4):562-77. doi: 10.1016/j.jmb.2010.08.048. Epub 2010 Sep 17.

PMID:
20850457
46.

Visceral Kaposi's sarcoma remission after intestinal transplant. First case report and systematic literature review.

D'Amico F, Fuxman C, Nachman F, Bitetti L, Fauda M, Echevarria C, Solar H, Politi P, Cabanne A, Mauriño E, Ruf A, Gondolesi GE.

Transplantation. 2010 Sep 15;90(5):547-54. doi: 10.1097/TP.0b013e3181ea3936.

PMID:
20625354
47.

Structure of the human fatty acid synthase KS-MAT didomain as a framework for inhibitor design.

Pappenberger G, Benz J, Gsell B, Hennig M, Ruf A, Stihle M, Thoma R, Rudolph MG.

J Mol Biol. 2010 Mar 26;397(2):508-19. doi: 10.1016/j.jmb.2010.01.066. Epub 2010 Feb 2.

PMID:
20132826
48.

The PFA-100R cannot detect blood group-dependent inhibition of platelet function by eptifibatide or abciximab at therapeutic plasma concentrations.

Feuring M, Ruf A, Schultz A, Wehling M.

Platelets. 2010;21(3):176-82. doi: 10.3109/09537100903518260.

PMID:
20121459
49.

Sulfonylureido thiazoles as fructose-1,6-bisphosphatase inhibitors for the treatment of type-2 diabetes.

Kitas E, Mohr P, Kuhn B, Hebeisen P, Wessel HP, Haap W, Ruf A, Benz J, Joseph C, Huber W, Sanchez RA, Paehler A, Benardeau A, Gubler M, Schott B, Tozzo E.

Bioorg Med Chem Lett. 2010 Jan 15;20(2):594-9. doi: 10.1016/j.bmcl.2009.11.093. Epub 2009 Nov 22.

PMID:
19969452
50.

Molecular switch in the glucocorticoid receptor: active and passive antagonist conformations.

Schoch GA, D'Arcy B, Stihle M, Burger D, Bär D, Benz J, Thoma R, Ruf A.

J Mol Biol. 2010 Jan 22;395(3):568-77. doi: 10.1016/j.jmb.2009.11.011. Epub 2009 Nov 11.

PMID:
19913032

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