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Items: 28

1.

Comparing modalities of conducting the six-minute walk test in healthy children and adolescents.

Rauchenzauner M, Schneider J, Colleselli V, Ruepp M, Cortina G, Högler W, Neururer S, Geiger R.

Minerva Pediatr. 2019 Jun;71(3):229-234. doi: 10.23736/S0026-4946.18.05185-X.

PMID:
31017381
2.

Targeting CD47 in Anaplastic Thyroid Carcinoma Enhances Tumor Phagocytosis by Macrophages and Is a Promising Therapeutic Strategy.

Schürch CM, Roelli MA, Forster S, Wasmer MH, Brühl F, Maire RS, Di Pancrazio S, Ruepp MD, Giger R, Perren A, Schmitt AM, Krebs P, Charles RP, Dettmer MS.

Thyroid. 2019 Jul;29(7):979-992. doi: 10.1089/thy.2018.0555. Epub 2019 May 10.

3.

The Solution Structure of FUS Bound to RNA Reveals a Bipartite Mode of RNA Recognition with Both Sequence and Shape Specificity.

Loughlin FE, Lukavsky PJ, Kazeeva T, Reber S, Hock EM, Colombo M, Von Schroetter C, Pauli P, Cléry A, Mühlemann O, Polymenidou M, Ruepp MD, Allain FH.

Mol Cell. 2019 Feb 7;73(3):490-504.e6. doi: 10.1016/j.molcel.2018.11.012. Epub 2018 Dec 20.

PMID:
30581145
4.

Mapping the Orthosteric Binding Site of the Human 5-HT3 Receptor Using Photo-cross-linking Antagonists.

Jack T, Leuenberger M, Ruepp MD, Vernekar SKV, Thompson AJ, Braga-Lagache S, Heller M, Lochner M.

ACS Chem Neurosci. 2019 Jan 16;10(1):438-450. doi: 10.1021/acschemneuro.8b00327. Epub 2018 Sep 11.

PMID:
30149702
5.

Hypertonic Stress Causes Cytoplasmic Translocation of Neuronal, but Not Astrocytic, FUS due to Impaired Transportin Function.

Hock EM, Maniecka Z, Hruska-Plochan M, Reber S, Laferrière F, Sahadevan M K S, Ederle H, Gittings L, Pelkmans L, Dupuis L, Lashley T, Ruepp MD, Dormann D, Polymenidou M.

Cell Rep. 2018 Jul 24;24(4):987-1000.e7. doi: 10.1016/j.celrep.2018.06.094.

6.

Phase Separation of FUS Is Suppressed by Its Nuclear Import Receptor and Arginine Methylation.

Hofweber M, Hutten S, Bourgeois B, Spreitzer E, Niedner-Boblenz A, Schifferer M, Ruepp MD, Simons M, Niessing D, Madl T, Dormann D.

Cell. 2018 Apr 19;173(3):706-719.e13. doi: 10.1016/j.cell.2018.03.004.

7.

The emerging role of minor intron splicing in neurological disorders.

Jutzi D, Akinyi MV, Mechtersheimer J, Frilander MJ, Ruepp MD.

Cell Stress. 2018 Feb 22;2(3):40-54. doi: 10.15698/cst2018.03.126. Review.

8.

CRISPR-Trap: a clean approach for the generation of gene knockouts and gene replacements in human cells.

Reber S, Mechtersheimer J, Nasif S, Benitez JA, Colombo M, Domanski M, Jutzi D, Hedlund E, Ruepp MD.

Mol Biol Cell. 2018 Jan 15;29(2):75-83. doi: 10.1091/mbc.E17-05-0288. Epub 2017 Nov 22.

9.

The binding orientations of structurally-related ligands can differ; A cautionary note.

Ruepp MD, Wei H, Leuenberger M, Lochner M, Thompson AJ.

Neuropharmacology. 2017 Jun;119:48-61. doi: 10.1016/j.neuropharm.2017.01.023. Epub 2017 Jan 27.

10.

The binding orientation of epibatidine at α7 nACh receptors.

Thompson AJ, Metzger S, Lochner M, Ruepp MD.

Neuropharmacology. 2017 Apr;116:421-428. doi: 10.1016/j.neuropharm.2017.01.008. Epub 2017 Jan 12.

11.

Minor intron splicing is regulated by FUS and affected by ALS-associated FUS mutants.

Reber S, Stettler J, Filosa G, Colombo M, Jutzi D, Lenzken SC, Schweingruber C, Bruggmann R, Bachi A, Barabino SM, Mühlemann O, Ruepp MD.

EMBO J. 2016 Jul 15;35(14):1504-21. doi: 10.15252/embj.201593791. Epub 2016 Jun 1.

12.

Identification of Interactions in the NMD Complex Using Proximity-Dependent Biotinylation (BioID).

Schweingruber C, Soffientini P, Ruepp MD, Bachi A, Mühlemann O.

PLoS One. 2016 Mar 2;11(3):e0150239. doi: 10.1371/journal.pone.0150239. eCollection 2016.

13.

Monomethylated and unmethylated FUS exhibit increased binding to Transportin and distinguish FTLD-FUS from ALS-FUS.

Suárez-Calvet M, Neumann M, Arzberger T, Abou-Ajram C, Funk E, Hartmann H, Edbauer D, Kremmer E, Göbl C, Resch M, Bourgeois B, Madl T, Reber S, Jutzi D, Ruepp MD, Mackenzie IR, Ansorge O, Dormann D, Haass C.

Acta Neuropathol. 2016 Apr;131(4):587-604. doi: 10.1007/s00401-016-1544-2. Epub 2016 Feb 19.

PMID:
26895297
14.

FUS/TLS contributes to replication-dependent histone gene expression by interaction with U7 snRNPs and histone-specific transcription factors.

Raczynska KD, Ruepp MD, Brzek A, Reber S, Romeo V, Rindlisbacher B, Heller M, Szweykowska-Kulinska Z, Jarmolowski A, Schümperli D.

Nucleic Acids Res. 2015 Nov 16;43(20):9711-28. doi: 10.1093/nar/gkv794. Epub 2015 Aug 6.

15.

A fluorescent approach for identifying P2X1 ligands.

Ruepp MD, Brozik JA, de Esch IJ, Farndale RW, Murrell-Lagnado RD, Thompson AJ.

Neuropharmacology. 2015 Nov;98:13-21. doi: 10.1016/j.neuropharm.2015.05.016. Epub 2015 May 28.

16.

Tracking individual membrane proteins and their biochemistry: The power of direct observation.

Barden AO, Goler AS, Humphreys SC, Tabatabaei S, Lochner M, Ruepp MD, Jack T, Simonin J, Thompson AJ, Jones JP, Brozik JA.

Neuropharmacology. 2015 Nov;98:22-30. doi: 10.1016/j.neuropharm.2015.05.003. Epub 2015 May 18. Review.

PMID:
25998277
17.

Sex-, age-, and height-specific reference curves for the 6-min walk test in healthy children and adolescents.

Saraff V, Schneider J, Colleselli V, Ruepp M, Rauchenzauner M, Neururer S, Geiger R, Högler W.

Eur J Pediatr. 2015 Jun;174(6):837-40. doi: 10.1007/s00431-014-2454-8. Epub 2014 Dec 10.

PMID:
25491900
18.

Characterizing new fluorescent tools for studying 5-HT₃ receptor pharmacology.

Jack T, Simonin J, Ruepp MD, Thompson AJ, Gertsch J, Lochner M.

Neuropharmacology. 2015 Mar;90:63-73. doi: 10.1016/j.neuropharm.2014.11.007. Epub 2014 Nov 22.

PMID:
25460187
19.

Synthesis and characterization of photoaffinity probes that target the 5-HT3 receptor.

Jack T, Ruepp MD, Thompson AJ, Mühlemann O, Lochner M.

Chimia (Aarau). 2014;68(4):239-42. doi: 10.2533/chimia.2014.239.

PMID:
24983606
20.

Effect of combined systemic and local morpholino treatment on the spinal muscular atrophy Δ7 mouse model phenotype.

Nizzardo M, Simone C, Salani S, Ruepp MD, Rizzo F, Ruggieri M, Zanetta C, Brajkovic S, Moulton HM, Müehlemann O, Bresolin N, Comi GP, Corti S.

Clin Ther. 2014 Mar 1;36(3):340-56.e5. doi: 10.1016/j.clinthera.2014.02.004.

PMID:
24636820
21.

Comparison of EJC-enhanced and EJC-independent NMD in human cells reveals two partially redundant degradation pathways.

Metze S, Herzog VA, Ruepp MD, Mühlemann O.

RNA. 2013 Oct;19(10):1432-48. doi: 10.1261/rna.038893.113. Epub 2013 Aug 20.

22.

Paraquat modulates alternative pre-mRNA splicing by modifying the intracellular distribution of SRPK2.

Vivarelli S, Lenzken SC, Ruepp MD, Ranzini F, Maffioletti A, Alvarez R, Mühlemann O, Barabino SM.

PLoS One. 2013 Apr 16;8(4):e61980. doi: 10.1371/journal.pone.0061980. Print 2013.

23.

mRNA 3' end processing and more--multiple functions of mammalian cleavage factor I-68.

Ruepp MD, Schümperli D, Barabino SM.

Wiley Interdiscip Rev RNA. 2011 Jan-Feb;2(1):79-91. doi: 10.1002/wrna.35. Review.

PMID:
21956970
24.

Interactions of CstF-64, CstF-77, and symplekin: implications on localisation and function.

Ruepp MD, Schweingruber C, Kleinschmidt N, Schümperli D.

Mol Biol Cell. 2011 Jan 1;22(1):91-104. doi: 10.1091/mbc.E10-06-0543. Epub 2010 Nov 30.

25.

The 68 kDa subunit of mammalian cleavage factor I interacts with the U7 small nuclear ribonucleoprotein and participates in 3'-end processing of animal histone mRNAs.

Ruepp MD, Vivarelli S, Pillai RS, Kleinschmidt N, Azzouz TN, Barabino SM, Schümperli D.

Nucleic Acids Res. 2010 Nov;38(21):7637-50. doi: 10.1093/nar/gkq613. Epub 2010 Jul 15.

26.

Mammalian pre-mRNA 3' end processing factor CF I m 68 functions in mRNA export.

Ruepp MD, Aringhieri C, Vivarelli S, Cardinale S, Paro S, Schümperli D, Barabino SM.

Mol Biol Cell. 2009 Dec;20(24):5211-23. doi: 10.1091/mbc.E09-05-0389.

27.

Rescue of a severe mouse model for spinal muscular atrophy by U7 snRNA-mediated splicing modulation.

Meyer K, Marquis J, Trüb J, Nlend Nlend R, Verp S, Ruepp MD, Imboden H, Barde I, Trono D, Schümperli D.

Hum Mol Genet. 2009 Feb 1;18(3):546-55. doi: 10.1093/hmg/ddn382. Epub 2008 Nov 13.

PMID:
19010792
28.

Efficacy of Artichoke dry extract in patients with hyperlipoproteinemia.

Englisch W, Beckers C, Unkauf M, Ruepp M, Zinserling V.

Arzneimittelforschung. 2000 Mar;50(3):260-5.

PMID:
10758778

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