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Items: 31

1.

Protein association changes in the Hedgehog signaling complex mediate differential signaling strength.

Giordano C, Ruel L, Poux C, Therond P.

Development. 2018 Dec 12;145(24). pii: dev166850. doi: 10.1242/dev.166850.

2.

Public Knowledge and Credibility Perceptions of the FDA as a Tobacco Regulator.

Schmidt AM, Jarman KL, Ranney LM, Queen TL, Noar SM, Ruel L, Agans R, Hannan A, Goldstein AO.

Nicotine Tob Res. 2018 Sep 25;20(11):1310-1316. doi: 10.1093/ntr/ntx215.

3.

Regulation of the protein kinase activity of ShaggyZeste-white3 by components of the Wingless pathway in Drosophila cells and embryos.

Ruel L, Stambolic V, Ali A, Manoukian AS, Woodgett JR.

J Biol Chem. 2016 Oct 28;291(44):23364. No abstract available.

4.

Switch of PKA substrates from Cubitus interruptus to Smoothened in the Hedgehog signalosome complex.

Ranieri N, Thérond PP, Ruel L.

Nat Commun. 2014 Oct 7;5:5034. doi: 10.1038/ncomms6034.

PMID:
25289679
5.

A genome-wide RNAi screen identifies regulators of cholesterol-modified hedgehog secretion in Drosophila.

Aikin R, Cervantes A, D'Angelo G, Ruel L, Lacas-Gervais S, Schaub S, Thérond P.

PLoS One. 2012;7(3):e33665. doi: 10.1371/journal.pone.0033665. Epub 2012 Mar 14.

6.

Distinct phosphorylations on kinesin costal-2 mediate differential hedgehog signaling strength.

Ranieri N, Ruel L, Gallet A, Raisin S, Thérond PP.

Dev Cell. 2012 Feb 14;22(2):279-94. doi: 10.1016/j.devcel.2011.12.002. Epub 2012 Feb 2.

7.

Dynamic phosphorylation of the kinesin Costal-2 in vivo reveals requirement of fused kinase activity for all levels of hedgehog signalling.

Raisin S, Ruel L, Ranieri N, Staccini-Lavenant L, Thérond PP.

Dev Biol. 2010 Aug 1;344(1):119-28. doi: 10.1016/j.ydbio.2010.04.021. Epub 2010 May 9.

8.

Variations in Hedgehog signaling: divergence and perpetuation in Sufu regulation of Gli.

Ruel L, Thérond PP.

Genes Dev. 2009 Aug 15;23(16):1843-8. doi: 10.1101/gad.1838109.

9.

Tow (Target of Wingless), a novel repressor of the Hedgehog pathway in Drosophila.

Ayers KL, Rodriguez R, Gallet A, Ruel L, Thérond P.

Dev Biol. 2009 May 15;329(2):280-93. doi: 10.1016/j.ydbio.2009.02.037. Epub 2009 Mar 10.

10.

Liver cirrhosis: intravoxel incoherent motion MR imaging--pilot study.

Luciani A, Vignaud A, Cavet M, Nhieu JT, Mallat A, Ruel L, Laurent A, Deux JF, Brugieres P, Rahmouni A.

Radiology. 2008 Dec;249(3):891-9. doi: 10.1148/radiol.2493080080.

PMID:
19011186
11.

Phosphorylation of the atypical kinesin Costal2 by the kinase Fused induces the partial disassembly of the Smoothened-Fused-Costal2-Cubitus interruptus complex in Hedgehog signalling.

Ruel L, Gallet A, Raisin S, Truchi A, Staccini-Lavenant L, Cervantes A, Thérond PP.

Development. 2007 Oct;134(20):3677-89. Epub 2007 Sep 19.

12.

Human receptors patched and smoothened partially transduce hedgehog signal when expressed in Drosophila cells.

De Rivoyre M, Ruel L, Varjosalo M, Loubat A, Bidet M, Thérond P, Mus-Veteau I.

J Biol Chem. 2006 Sep 29;281(39):28584-95. Epub 2006 Jul 25.

13.

Cholesterol modification is necessary for controlled planar long-range activity of Hedgehog in Drosophila epithelia.

Gallet A, Ruel L, Staccini-Lavenant L, Thérond PP.

Development. 2006 Feb;133(3):407-18. Epub 2006 Jan 5.

14.

Mouse myodulin, a new potential angiogenic factor, functionally expressed in yeast.

Pisani DF, Rivoyre MD, Ruel L, Bonino F, Bidet M, Dechesne CA, Mus-Veteau I.

Biochem Biophys Res Commun. 2005 Jun 3;331(2):552-6.

PMID:
15850795
15.

Human receptor Smoothened, a mediator of Hedgehog signalling, expressed in its native conformation in yeast.

De Rivoyre M, Bonino F, Ruel L, Bidet M, Thérond P, Mus-Veteau I.

FEBS Lett. 2005 Feb 28;579(6):1529-33.

16.

Water diffusion compartmentation at high b values in ischemic human brain.

Brugières P, Thomas P, Maraval A, Hosseini H, Combes C, Chafiq A, Ruel L, Breil S, Peschanski M, Gaston A.

AJNR Am J Neuroradiol. 2004 May;25(5):692-8.

17.

Comparison of in vitro and in vivo MRI of the spine using parallel imaging.

Ruel L, Brugières P, Luciani A, Breil S, Mathieu D, Rahmouni A.

AJR Am J Roentgenol. 2004 Mar;182(3):749-55.

PMID:
14975981
18.

Stability and association of Smoothened, Costal2 and Fused with Cubitus interruptus are regulated by Hedgehog.

Ruel L, Rodriguez R, Gallet A, Lavenant-Staccini L, Thérond PP.

Nat Cell Biol. 2003 Oct;5(10):907-13. Epub 2003 Oct 1.

PMID:
14523402
19.
20.

Virological features and clinical manifestations associated with human metapneumovirus: a new paramyxovirus responsible for acute respiratory-tract infections in all age groups.

Boivin G, Abed Y, Pelletier G, Ruel L, Moisan D, Côté S, Peret TC, Erdman DD, Anderson LJ.

J Infect Dis. 2002 Nov 1;186(9):1330-4. Epub 2002 Oct 8.

PMID:
12402203
21.

The conserved PI3'K/PTEN/Akt signaling pathway regulates both cell size and survival in Drosophila.

Scanga SE, Ruel L, Binari RC, Snow B, Stambolic V, Bouchard D, Peters M, Calvieri B, Mak TW, Woodgett JR, Manoukian AS.

Oncogene. 2000 Aug 17;19(35):3971-7.

22.
23.

Presenilin mutations associated with Alzheimer disease cause defective intracellular trafficking of beta-catenin, a component of the presenilin protein complex.

Nishimura M, Yu G, Levesque G, Zhang DM, Ruel L, Chen F, Milman P, Holmes E, Liang Y, Kawarai T, Jo E, Supala A, Rogaeva E, Xu DM, Janus C, Levesque L, Bi Q, Duthie M, Rozmahel R, Mattila K, Lannfelt L, Westaway D, Mount HT, Woodgett J, St George-Hyslop P, et al.

Nat Med. 1999 Feb;5(2):164-9.

PMID:
9930863
24.

Genetic analysis of protein kinase B (AKT) in Drosophila.

Staveley BE, Ruel L, Jin J, Stambolic V, Mastronardi FG, Heitzler P, Woodgett JR, Manoukian AS.

Curr Biol. 1998 May 7;8(10):599-602.

25.

Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells.

Stambolic V, Ruel L, Woodgett JR.

Curr Biol. 1996 Dec 1;6(12):1664-8. Erratum in: Curr Biol 1997 Mar 1;7(3):196.

26.
27.

Drosophila shaggy kinase and rat glycogen synthase kinase-3 have conserved activities and act downstream of Notch.

Ruel L, Bourouis M, Heitzler P, Pantesco V, Simpson P.

Nature. 1993 Apr 8;362(6420):557-60.

PMID:
8385271
28.

Functional significance of a family of protein kinases encoded at the shaggy locus in Drosophila.

Ruel L, Pantesco V, Lutz Y, Simpson P, Bourouis M.

EMBO J. 1993 Apr;12(4):1657-69.

29.

A dual role for the protein kinase shaggy in the repression of achaete-scute.

Simpson P, Ruel L, Heitzler P, Bourouis M.

Dev Suppl. 1993:29-39. Review.

PMID:
8049485
30.

Delta, notch, and shaggy: elements of a lateral signaling pathway in Drosophila.

Simpson P, Bourouis M, Heitzler P, Ruel L, Haenlin M, Ramain P.

Cold Spring Harb Symp Quant Biol. 1992;57:391-400. Review. No abstract available.

PMID:
1339674
31.

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